JPH0588719B2 - - Google Patents
Info
- Publication number
- JPH0588719B2 JPH0588719B2 JP63294472A JP29447288A JPH0588719B2 JP H0588719 B2 JPH0588719 B2 JP H0588719B2 JP 63294472 A JP63294472 A JP 63294472A JP 29447288 A JP29447288 A JP 29447288A JP H0588719 B2 JPH0588719 B2 JP H0588719B2
- Authority
- JP
- Japan
- Prior art keywords
- compound
- poultry
- growth
- compound according
- cattle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 244000005700 microbiome Species 0.000 claims abstract description 21
- 238000000855 fermentation Methods 0.000 claims abstract description 20
- 230000004151 fermentation Effects 0.000 claims abstract description 20
- 241000283690 Bos taurus Species 0.000 claims abstract description 15
- 150000001875 compounds Chemical class 0.000 claims description 50
- 238000000034 method Methods 0.000 claims description 30
- 244000144977 poultry Species 0.000 claims description 23
- 239000000203 mixture Substances 0.000 claims description 20
- 241000282887 Suidae Species 0.000 claims description 11
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 10
- 235000016709 nutrition Nutrition 0.000 claims description 8
- 241000187362 Actinomadura Species 0.000 claims description 7
- 208000015181 infectious disease Diseases 0.000 claims description 7
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 6
- 125000002091 cationic group Chemical group 0.000 claims description 6
- 239000012043 crude product Substances 0.000 claims description 6
- 238000004519 manufacturing process Methods 0.000 claims description 6
- 229910052757 nitrogen Inorganic materials 0.000 claims description 5
- 230000001737 promoting effect Effects 0.000 claims description 5
- 239000011734 sodium Substances 0.000 claims description 5
- 229910052799 carbon Inorganic materials 0.000 claims description 4
- 235000015097 nutrients Nutrition 0.000 claims description 4
- 229910052708 sodium Inorganic materials 0.000 claims description 4
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical class [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 claims description 3
- 238000001914 filtration Methods 0.000 claims description 2
- 238000004108 freeze drying Methods 0.000 claims description 2
- 239000002244 precipitate Substances 0.000 claims description 2
- 150000003385 sodium Chemical class 0.000 claims 1
- 238000001694 spray drying Methods 0.000 claims 1
- 230000003115 biocidal effect Effects 0.000 abstract description 22
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract description 13
- 241000287828 Gallus gallus Species 0.000 abstract description 9
- 235000013330 chicken meat Nutrition 0.000 abstract description 9
- 125000003367 polycyclic group Chemical group 0.000 abstract description 6
- 230000002378 acidificating effect Effects 0.000 abstract description 3
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- 241000282898 Sus scrofa Species 0.000 abstract 1
- 230000001165 anti-coccidial effect Effects 0.000 abstract 1
- 238000002424 x-ray crystallography Methods 0.000 abstract 1
- 239000002609 medium Substances 0.000 description 24
- 229920001817 Agar Polymers 0.000 description 23
- 239000008272 agar Substances 0.000 description 23
- 235000013594 poultry meat Nutrition 0.000 description 18
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 16
- 239000000049 pigment Substances 0.000 description 16
- 239000003814 drug Substances 0.000 description 15
- 235000010633 broth Nutrition 0.000 description 13
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 12
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 12
- XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 12
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- 229940079593 drug Drugs 0.000 description 11
- 235000019698 starch Nutrition 0.000 description 10
- 239000008107 starch Substances 0.000 description 10
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 9
- 239000002253 acid Substances 0.000 description 9
- 239000006071 cream Substances 0.000 description 9
- 150000003839 salts Chemical class 0.000 description 9
- 210000004767 rumen Anatomy 0.000 description 8
- 238000012360 testing method Methods 0.000 description 8
- 239000002054 inoculum Substances 0.000 description 7
- 235000012054 meals Nutrition 0.000 description 7
- 159000000000 sodium salts Chemical class 0.000 description 7
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 6
- SRBFZHDQGSBBOR-IOVATXLUSA-N D-xylopyranose Chemical compound O[C@@H]1COC(O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-IOVATXLUSA-N 0.000 description 6
- 239000003242 anti bacterial agent Substances 0.000 description 6
- PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 description 6
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- 239000012141 concentrate Substances 0.000 description 6
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- 235000019260 propionic acid Nutrition 0.000 description 6
- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 description 6
- 241000201754 Actinomadura citrea Species 0.000 description 5
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- 238000011282 treatment Methods 0.000 description 5
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 4
- 241001465754 Metazoa Species 0.000 description 4
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 description 4
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 4
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 4
- 239000005018 casein Substances 0.000 description 4
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 description 4
- 235000021240 caseins Nutrition 0.000 description 4
- 239000003795 chemical substances by application Substances 0.000 description 4
- 239000003651 drinking water Substances 0.000 description 4
- 235000020188 drinking water Nutrition 0.000 description 4
- 239000012530 fluid Substances 0.000 description 4
- 239000008103 glucose Substances 0.000 description 4
- 239000001963 growth medium Substances 0.000 description 4
- 238000000338 in vitro Methods 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 239000012074 organic phase Substances 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- 241000894007 species Species 0.000 description 4
- 229940124597 therapeutic agent Drugs 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- 241001327993 Actinomadura livida Species 0.000 description 3
- 241000201779 Actinomadura macra Species 0.000 description 3
- 244000245659 Arcangelisia flava Species 0.000 description 3
- 244000063299 Bacillus subtilis Species 0.000 description 3
- 235000014469 Bacillus subtilis Nutrition 0.000 description 3
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 3
- 241000223932 Eimeria tenella Species 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- 229930091371 Fructose Natural products 0.000 description 3
- 239000005715 Fructose Substances 0.000 description 3
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 3
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 3
- 229930195725 Mannitol Natural products 0.000 description 3
- NTIZESTWPVYFNL-UHFFFAOYSA-N Methyl isobutyl ketone Chemical compound CC(C)CC(C)=O NTIZESTWPVYFNL-UHFFFAOYSA-N 0.000 description 3
- UIHCLUNTQKBZGK-UHFFFAOYSA-N Methyl isobutyl ketone Natural products CCC(C)C(C)=O UIHCLUNTQKBZGK-UHFFFAOYSA-N 0.000 description 3
- 241000282849 Ruminantia Species 0.000 description 3
- 229930006000 Sucrose Natural products 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 3
- PYMYPHUHKUWMLA-WDCZJNDASA-N arabinose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)C=O PYMYPHUHKUWMLA-WDCZJNDASA-N 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 3
- 229910000019 calcium carbonate Inorganic materials 0.000 description 3
- 238000007796 conventional method Methods 0.000 description 3
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- 239000000975 dye Substances 0.000 description 3
- 238000000921 elemental analysis Methods 0.000 description 3
- 238000011534 incubation Methods 0.000 description 3
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- 229910052500 inorganic mineral Inorganic materials 0.000 description 3
- 239000000594 mannitol Substances 0.000 description 3
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- 239000011707 mineral Substances 0.000 description 3
- 235000010755 mineral Nutrition 0.000 description 3
- 239000007003 mineral medium Substances 0.000 description 3
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 3
- 239000003921 oil Substances 0.000 description 3
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- 239000000243 solution Substances 0.000 description 3
- 235000012424 soybean oil Nutrition 0.000 description 3
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- 229960004793 sucrose Drugs 0.000 description 3
- 239000013589 supplement Substances 0.000 description 3
- MWOOGOJBHIARFG-UHFFFAOYSA-N vanillin Chemical compound COC1=CC(C=O)=CC=C1O MWOOGOJBHIARFG-UHFFFAOYSA-N 0.000 description 3
- FGQOOHJZONJGDT-UHFFFAOYSA-N vanillin Natural products COC1=CC(O)=CC(C=O)=C1 FGQOOHJZONJGDT-UHFFFAOYSA-N 0.000 description 3
- 235000012141 vanillin Nutrition 0.000 description 3
- GMKMEZVLHJARHF-UHFFFAOYSA-N (2R,6R)-form-2.6-Diaminoheptanedioic acid Natural products OC(=O)C(N)CCCC(N)C(O)=O GMKMEZVLHJARHF-UHFFFAOYSA-N 0.000 description 2
- BBBFYZOJHSYQMW-LGDQNDJISA-N (2s)-2,4-diamino-4-oxobutanoic acid;(2r,3s,4r,5r)-2,3,4,5,6-pentahydroxyhexanal Chemical compound OC(=O)[C@@H](N)CC(N)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O BBBFYZOJHSYQMW-LGDQNDJISA-N 0.000 description 2
- LRFVTYWOQMYALW-UHFFFAOYSA-N 9H-xanthine Chemical compound O=C1NC(=O)NC2=C1NC=N2 LRFVTYWOQMYALW-UHFFFAOYSA-N 0.000 description 2
- 241000187256 Actinomadura cremea Species 0.000 description 2
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- 230000002829 reductive effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 150000003297 rubidium Chemical class 0.000 description 1
- 229910052701 rubidium Inorganic materials 0.000 description 1
- IGLNJRXAVVLDKE-UHFFFAOYSA-N rubidium atom Chemical compound [Rb] IGLNJRXAVVLDKE-UHFFFAOYSA-N 0.000 description 1
- WPFGFHJALYCVMO-UHFFFAOYSA-L rubidium carbonate Chemical compound [Rb+].[Rb+].[O-]C([O-])=O WPFGFHJALYCVMO-UHFFFAOYSA-L 0.000 description 1
- 229910000026 rubidium carbonate Inorganic materials 0.000 description 1
- NGFMICBWJRZIBI-UJPOAAIJSA-N salicin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=CC=CC=C1CO NGFMICBWJRZIBI-UJPOAAIJSA-N 0.000 description 1
- 229940120668 salicin Drugs 0.000 description 1
- 229960001548 salinomycin Drugs 0.000 description 1
- 235000019378 salinomycin Nutrition 0.000 description 1
- 238000007790 scraping Methods 0.000 description 1
- CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 description 1
- 201000010153 skin papilloma Diseases 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 235000011152 sodium sulphate Nutrition 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 239000004550 soluble concentrate Substances 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 230000003595 spectral effect Effects 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000003892 spreading Methods 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 239000008399 tap water Substances 0.000 description 1
- 235000020679 tap water Nutrition 0.000 description 1
- 229940126585 therapeutic drug Drugs 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 241001446247 uncultured actinomycete Species 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 229940075420 xanthine Drugs 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/195—Antibiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/825—Actinomadura
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Fodder In General (AREA)
- Saccharide Compounds (AREA)
- Feed For Specific Animals (AREA)
- Cold Air Circulating Systems And Constructional Details In Refrigerators (AREA)
- Light Receiving Elements (AREA)
- Steroid Compounds (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Detergent Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US1987/003095 WO1993012800A1 (en) | 1987-11-20 | 1987-11-20 | An acidic polycyclic ether useful as an anticoccidial agent and as a growth promotant |
| WO87/03095 | 1987-11-20 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH01165392A JPH01165392A (ja) | 1989-06-29 |
| JPH0588719B2 true JPH0588719B2 (en, 2012) | 1993-12-24 |
Family
ID=22202679
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP63294472A Granted JPH01165392A (ja) | 1987-11-20 | 1988-11-21 | 抗胞子虫症剤および成長促進剤として有益な酸性多環エーテル |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5147858A (en, 2012) |
| EP (1) | EP0317231B1 (en, 2012) |
| JP (1) | JPH01165392A (en, 2012) |
| AT (1) | ATE91687T1 (en, 2012) |
| DE (1) | DE3882490T2 (en, 2012) |
| DK (1) | DK644288A (en, 2012) |
| ES (1) | ES2058310T3 (en, 2012) |
| IE (1) | IE61964B1 (en, 2012) |
| PT (1) | PT89032B (en, 2012) |
| WO (1) | WO1993012800A1 (en, 2012) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5298524A (en) * | 1988-06-09 | 1994-03-29 | Pfizer Inc. | Acidic polycyclic ether antibiotic having an anticoccidial and growth promotant activity |
| US5043353A (en) * | 1989-10-10 | 1991-08-27 | Eli Lilly And Company | A80789 polyether antibiotic |
| US5242814A (en) * | 1989-10-10 | 1993-09-07 | Eli Lilly And Company | Polyether antibiotic |
| CA2091567A1 (en) * | 1990-10-04 | 1992-04-05 | Walter P. Cullen | Acidic polycyclic ether antibiotic |
| EP0558525B1 (en) * | 1990-11-16 | 1994-12-28 | Pfizer Inc. | Semduramicin premix |
| FR3078629B1 (fr) | 2018-03-12 | 2020-07-31 | Adisseo France Sas | Additif alimentaire a base de saponines pour le traitement de la coccidiose |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH579147A5 (en) * | 1973-03-09 | 1976-08-31 | Sandoz Ag | Antiparasitic streptomyces hygroscopicus metabolite - i.e. septamycine, as antibacterials, antiprotozoals, anthelminthics and coccidiostats |
| AR206353A1 (es) * | 1974-08-09 | 1976-07-15 | Pfizer | Un procedimiento para producir el compuesto 38295 antibiotico |
| US4148882A (en) * | 1977-06-24 | 1979-04-10 | Pfizer Inc. | Polycyclic ether antibiotics produced by new species of actinomycete |
| US4195079A (en) * | 1979-01-31 | 1980-03-25 | Pfizer Inc. | New polycyclic ether antibiotic |
| JPS577492A (en) * | 1980-06-13 | 1982-01-14 | Shionogi & Co Ltd | K-41 derivative |
| GB8417785D0 (en) * | 1984-07-12 | 1984-08-15 | Pfizer Ltd | Polycyclic ether antibiotic |
-
1987
- 1987-11-20 US US07/487,947 patent/US5147858A/en not_active Expired - Lifetime
- 1987-11-20 WO PCT/US1987/003095 patent/WO1993012800A1/en unknown
-
1988
- 1988-11-14 ES ES88310717T patent/ES2058310T3/es not_active Expired - Lifetime
- 1988-11-14 EP EP88310717A patent/EP0317231B1/en not_active Expired - Lifetime
- 1988-11-14 AT AT88310717T patent/ATE91687T1/de active
- 1988-11-14 DE DE88310717T patent/DE3882490T2/de not_active Expired - Fee Related
- 1988-11-18 IE IE346488A patent/IE61964B1/en not_active IP Right Cessation
- 1988-11-18 DK DK644288A patent/DK644288A/da not_active Application Discontinuation
- 1988-11-18 PT PT89032A patent/PT89032B/pt not_active IP Right Cessation
- 1988-11-21 JP JP63294472A patent/JPH01165392A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| DK644288D0 (da) | 1988-11-18 |
| WO1993012800A1 (en) | 1993-07-08 |
| US5147858A (en) | 1992-09-15 |
| ATE91687T1 (de) | 1993-08-15 |
| DE3882490D1 (de) | 1993-08-26 |
| EP0317231B1 (en) | 1993-07-21 |
| PT89032A (pt) | 1988-12-01 |
| IE883464L (en) | 1989-05-20 |
| PT89032B (pt) | 1993-02-26 |
| JPH01165392A (ja) | 1989-06-29 |
| IE61964B1 (en) | 1994-11-30 |
| DK644288A (da) | 1989-06-27 |
| EP0317231A3 (en) | 1990-04-18 |
| DE3882490T2 (de) | 1993-11-11 |
| ES2058310T3 (es) | 1994-11-01 |
| EP0317231A2 (en) | 1989-05-24 |
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