JPH05503629A - 抗ウィルス剤及び免疫原として使用される、非複製組換え製レトロウィルス粒子 - Google Patents

抗ウィルス剤及び免疫原として使用される、非複製組換え製レトロウィルス粒子

Info

Publication number
JPH05503629A
JPH05503629A JP3501082A JP50108291A JPH05503629A JP H05503629 A JPH05503629 A JP H05503629A JP 3501082 A JP3501082 A JP 3501082A JP 50108291 A JP50108291 A JP 50108291A JP H05503629 A JPH05503629 A JP H05503629A
Authority
JP
Japan
Prior art keywords
hiv
recombinant
particles
gene
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP3501082A
Other languages
English (en)
Japanese (ja)
Inventor
ハッファー,オマール,ケイ.
フ,シウ―ロク
セニア,アレン,ダブリュー
トラビス,ブルース,エム.
Original Assignee
オンコーゲン リミテッド パートナーシップ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by オンコーゲン リミテッド パートナーシップ filed Critical オンコーゲン リミテッド パートナーシップ
Publication of JPH05503629A publication Critical patent/JPH05503629A/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16111Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP3501082A 1989-11-20 1990-11-20 抗ウィルス剤及び免疫原として使用される、非複製組換え製レトロウィルス粒子 Pending JPH05503629A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43920589A 1989-11-20 1989-11-20
US439,205 1989-11-20

Publications (1)

Publication Number Publication Date
JPH05503629A true JPH05503629A (ja) 1993-06-17

Family

ID=23743729

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3501082A Pending JPH05503629A (ja) 1989-11-20 1990-11-20 抗ウィルス剤及び免疫原として使用される、非複製組換え製レトロウィルス粒子

Country Status (14)

Country Link
EP (1) EP0502105A4 (fi)
JP (1) JPH05503629A (fi)
KR (1) KR920703639A (fi)
AU (1) AU636944B2 (fi)
CA (1) CA2068713A1 (fi)
ES (1) ES2052478T1 (fi)
FI (1) FI922277A0 (fi)
GR (1) GR930300005T1 (fi)
HU (1) HUT60506A (fi)
NO (1) NO921969L (fi)
OA (1) OA09698A (fi)
TW (1) TW216446B (fi)
WO (1) WO1991007425A1 (fi)
ZA (1) ZA909302B (fi)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3034025B2 (ja) * 1989-06-01 2000-04-17 アプライド・バイオテクノロジー・インコーポレーテツド 自己アセンブルド欠損非自己増殖性ウイルス粒子
US5861282A (en) * 1989-10-16 1999-01-19 Whitehead Institute For Biomedical Research Non-infectious HIV particles and uses therefor
WO1991019803A1 (en) * 1990-06-19 1991-12-26 Applied Biotechnology, Incorporated Self assembled, defective, nonself-propagating viral particles
DE4124817A1 (de) * 1991-07-26 1993-01-28 Basf Ag Waessrige polymerisatdispersionen
ES2177530T3 (es) * 1991-11-08 2002-12-16 Upjohn Co Vacunas contra el virus de la leucemia felina.
AU2462392A (en) * 1992-04-14 1993-11-18 British Biotech Pharmaceuticals Limited Induction of CTL responses
US7001759B1 (en) 1993-01-26 2006-02-21 The Trustees Of The University Of Pennsylvania Compositions and methods for delivery of genetic material
EP1473369B1 (en) 1993-01-26 2009-01-07 The Trustees of the University of Pennsylvania (a corporation of Pennsylvania) Compositions and methods for delivery of genetic material
WO1994016737A1 (en) 1993-01-26 1994-08-04 Weiner David B Compositions and methods for delivery of genetic material
GB9304239D0 (en) * 1993-03-01 1993-04-21 British Bio Technology Viral particles
US5955342A (en) * 1994-08-15 1999-09-21 Connaught Laboratories Limited Non-infectious, replication-defective, self-assembling HIV-1 viral particles containing antigenic markers in the gag coding region
US6291157B1 (en) 1998-02-23 2001-09-18 Connaught Laboratories Limited Antigenically-marked non-infectious retrovirus-like particles
US5858838A (en) 1998-02-23 1999-01-12 Taiwan Semiconductor Manufacturing Company, Ltd. Method for increasing DRAM capacitance via use of a roughened surface bottom capacitor plate
US6080408A (en) 1994-08-22 2000-06-27 Connaught Laboratories Limited Human immunodeficiency virus type 1 nucleic acids devoid of long terminal repeats capable of encoding for non-infectious, immunogenic, retrovirus-like particles
WO1996030523A2 (en) * 1995-03-31 1996-10-03 Hans Wolf Antigen presentation system based on retrovirus-like particles
US6013506A (en) * 1995-06-05 2000-01-11 Wardley; Richard C. Feline leukemia virus vaccines
US6121021A (en) * 1997-12-16 2000-09-19 Connaught Laboratories Limited Constitutive expression of non-infectious HIV-like particles
DE69938062T2 (de) 1998-12-31 2009-01-15 Novartis Vaccines and Diagnostics, Inc., Emeryville Modifizierte hiv env polypeptide
JP2003523721A (ja) 1998-12-31 2003-08-12 カイロン コーポレイション 抗原性hivc型ポリペプチドをコードするポリヌクレオチド、ポリペプチド、およびそれらの使用
US8623379B2 (en) 2000-03-02 2014-01-07 Emory University Compositions and methods for generating an immune response
CA2401974C (en) 2000-03-02 2013-07-02 Emory University Dna expression vectors and methods of use
DE60234018D1 (de) * 2001-03-08 2009-11-26 Univ Emory Mva-exprimierende modifizierte hiv-envelope-, gag-, und pol-gene
AU2002320314A1 (en) 2001-07-05 2003-01-21 Chiron, Corporation Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof
US20030170614A1 (en) 2001-08-31 2003-09-11 Megede Jan Zur Polynucleotides encoding antigenic HIV type B polypeptides, polypeptides and uses thereof
US9839684B2 (en) 2011-04-06 2017-12-12 Biovaxim Limited Pharmaceutical compositions comprising inactivated HIV viral particles and non-pathogenic lactobacilli for the induction of antigen-specific immunotolerance
WO2017015463A2 (en) 2015-07-21 2017-01-26 Modernatx, Inc. Infectious disease vaccines
WO2018170256A1 (en) 2017-03-15 2018-09-20 Modernatx, Inc. Herpes simplex virus vaccine
US11045540B2 (en) 2017-03-15 2021-06-29 Modernatx, Inc. Varicella zoster virus (VZV) vaccine
EP3938379A4 (en) * 2019-03-15 2023-02-22 ModernaTX, Inc. HIV RNA VACCINE

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4752565A (en) * 1986-04-07 1988-06-21 The United States Of America As Represented By The Department Of Health And Human Services Cell line producing AIDS viral antigens without producing infectious virus particles
JPH02203783A (ja) * 1989-02-02 1990-08-13 Banyu Pharmaceut Co Ltd 抗原性を有する非感染性エイズウイルス産生クローン化ヒトt細胞
JP3140757B2 (ja) * 1989-02-06 2001-03-05 デイナ・フアーバー・キヤンサー・インステイテユート パッケージング欠陥hivプロウイルス、細胞系及びその使用
GB8923123D0 (en) * 1989-10-13 1989-11-29 Connaught Lab A vaccine for human immunodeficiency virus
EP0496794A1 (en) * 1989-10-16 1992-08-05 Whitehead Institute For Biomedical Research Non-infectious hiv-1 particles and uses therefor

Also Published As

Publication number Publication date
EP0502105A1 (en) 1992-09-09
WO1991007425A1 (en) 1991-05-30
ZA909302B (en) 1991-09-25
CA2068713A1 (en) 1991-05-21
ES2052478T1 (es) 1994-07-16
FI922277A (fi) 1992-05-19
GR930300005T1 (fi) 1993-04-28
AU636944B2 (en) 1993-05-13
EP0502105A4 (en) 1993-02-24
OA09698A (en) 1993-08-30
TW216446B (fi) 1993-11-21
FI922277A0 (fi) 1992-05-19
AU6905591A (en) 1991-06-13
KR920703639A (ko) 1992-12-18
NO921969D0 (no) 1992-05-19
HUT60506A (en) 1992-09-28
NO921969L (no) 1992-06-26
HU9201659D0 (en) 1992-08-28

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