JPH053905A - Liquid transfer device - Google Patents

Abstract

PURPOSE:To simplify and facilitate the communication of vessels, in a liquid transfer device for titration and injection, by forming communicating parts to a flexible vessel for solution or dilution and to a drug vessel respectively, and by fitting the respictive communicating parts by relatively moving them, so that both vessels are allowed to communicate with each other via both the communicating parts. CONSTITUTION:A vial (drug vessel) 5 is relatively approched to a bag (flexible vessel) 3. Thereby, a second communicating passage 11 that has been allowed to communicate with the inside of the bag 3 is slidably moved and fitted to a first communicating passage 8 that has been allowed to communicate with the inside of the vial 5, and a communicating hole 15 is opened to the inside of the vial 5. Thus, the vial 5 is allowed to communicate with the bag 3, and by applying a pressure to the bag 3, the solution inside the bag 3 can be transferred inside the vial 5.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an infusion device, and more particularly to an infusion device (container) used for drip injection.

[0002]

2. Description of the Related Art Conventionally, in medical institutions such as hospitals,
The powdered drug or freeze-dried drug contained in a container such as a vial is dissolved and used as an infusion solution for drip injection. At this time, the container containing the drug and the container containing the solution of the drug are double-ended needles or Connection is made using a connecting tool such as a connecting pipe, and the solution is transferred to a container containing the drug to dissolve the drug.

However, this operation is complicated and time-consuming, and in addition, the operation of making a connection hole in the container containing the drug in the open air may contaminate the drug.

Therefore, as a solution to the above problems, an infusion device (container) as disclosed in Japanese Patent Publication No. 61-501129 is proposed.

As shown in FIG. 3, this infusion device has a capsule (102) for accommodating a vial (101) as a drug container and a flexible container (103) containing a solution having a drug outlet. ) Are connected by a tube (104). And in the tube (104)
A hollow puncture needle (105) is attached to the vial (101) side, and a breaking member (10) is attached to the flexible container (103) side.
6) is installed. The breaking member (106) closes the passage in the tube (104) and blocks the flow of liquid.

In use, the cap (107) on top of the capsule (102) is pressed with a finger to vial (101).
Is pushed down, the rubber stopper (108) of the vial (101) is penetrated by the puncture needle (105), and the flexible container (103) and the vial (101) are first connected. Then, the tube (1
The breaking member (106) in 04) is manually bent, thereby opening the passage in the tube (104) to mix the drug and the solution.

[0007]

However, regarding the point that the drug container and the flexible container containing the dissolution liquid are communicated and mixed in the infusion device, it is said to be improved by the puncture needle (105). After piercing the rubber stopper (108) of the vial (101), the breaking member (106) must be broken by hand to open the passage, which is still quite troublesome. In addition, if the breaking member (106) is incompletely bent, it is difficult for the liquid to pass through, and there is a problem that it takes time to dissolve the liquid. Further, there is a problem that the cost becomes high because the number of parts is large.

The present invention has been made in view of the above problems, and makes it possible to surely and easily communicate a drug container with a solution or diluent (hereinafter referred to as solution) container with a simple structure.
It is an object of the present invention to provide an infusion device that can mix a drug and a solution after communication in a short time and is low in cost.

[0009]

SUMMARY OF THE INVENTION The present invention is directed to a flexible container having a solution or a diluent contained therein, a drug container having a drug contained therein, a flexible container and a drug container. A first communication passage communicating with one of the containers, and a second communication passage communicating with the other container and slidably fitted and locked in the first communication passage in the direction of the one container. The second communication passage is closed by the inner wall of the first communication passage so that the road end is closed and the road side wall is opened in the one container by moving toward the one container. The infusion device is provided with a communication hole.

That is, according to the present invention, by connecting a drug container and a flexible container through a specific communication passage formed in each container, when both containers are moved relative to each other, the insides of both containers are made to communicate with each other. The drug can be mixed with the solution or diluent to prepare an infusion solution.

Communication between the two containers is carried out by relatively moving the drug container and the flexible container, that is, the first communication passage communicating with either one of the containers and the second communication passage communicating with the other container. When it is moved toward the container, the communication hole of the second communication passage is opened in the one container, and the inside of the drug container and the inside of the flexible container can be communicated with each other. in short,
The infusion solution can be reliably prepared by a simple operation of moving the drug container and the flexible container relatively.

[0012]

DESCRIPTION OF THE PREFERRED EMBODIMENTS The present invention will be described in detail below based on the embodiments shown in the drawings. The present invention is not limited to this.

First, referring to FIG. 1, an infusion device (container)
(1) is a flexible container (hereinafter referred to as a bag) (3) in which a solution is stored therein in a sterile state, and a drug vial as a drug container in which a solid drug is stored therein in a sterile state. It is provided with (5) (hereinafter referred to as a vial) and a communication part (2) for communicating the vial and the bag (3). In addition, (4) is a cap provided on the upper part of the vial (5), (6) is a suspender made of soft polypropylene resin, and (7) is an infusion outlet provided on the lower part of the bag (3).

The bag (3) is a container made of a flexible material such as a soft vinyl chloride resin, a polyolefin resin, or an ethylene vinyl acetate copolymer. A polyolefin resin is preferable because it has excellent chemical resistance and a small amount of eluate in the solution. Examples of the solution to be put in the bag (3) include physiological saline, 5% glucose solution,
In addition to distilled water for injection, solutions containing various electrolytes are used.

The vial (5) (main body of the container) is a vial made of plastic or glass, and a solid medicine is put therein. Antibiotics, anti-tumor agents, anti-ulcer agents and the like are examples of the medicine to be placed in the vial (5). Antibiotics include cefazolin sodium, ceftizoxime sodium, cefotiam hydrochloride, cefmenoxime hydrochloride, cefacetril sodium, cefamandole sodium, cephaloridine, cefataxime sodium, cefatetan sodium, cefoperazone sodium, cefsulodin sodium, cef Cefem antibiotics such as tezole sodium, cefpyramide sodium, cefmetazole sodium, cefuroxime sodium, etc. is there. As an antitumor agent, mitomycin C,
Examples include fluorouracil, tegafur, and cytarabine. As an anti-ulcer agent, famotidine, ranitidine hydrochloride,
There is cimetidine.

The communication part (2) is connected to the first communication path (8) which communicates with the inside of the vial (5) and the first communication path (8) which is communicated with the inside of the bag (3) and the first communication path. A second communication passage (11) movably fitted to the second communication passage, extends outward from the root of the second communication passage on the bag (3) side, and is slidably fitted and locked together with the first communication passage (8). It consists mainly of a flange (9).

The first communication passage (8) has a ring-shaped ridge (10) protruding outward at the tip opening, while the flange (9) has a ring-shaped ridge (10) at the tip thereof on the side of the vial (5). It has an inward ring-shaped ridge (12) slidably locked to.
The second communication passage (11) has a large diameter portion (13) communicating with the bag (3), a small diameter portion (14) that is reduced in diameter from the large diameter portion and extends integrally, and further extends integrally from the small diameter portion, A rubber plug portion (16) having a communication hole (15) closed at the tip (road end) in the vial (5) direction and closed at the trunk wall (road side wall) by the inner wall of the first communication passage (8); Consists of. This rubber stopper is molded with a communication hole (15) and is integrally joined to the small diameter portion and the tip of (14) with an adhesive. Eventually, the rubber plug portion (16) is formed with a passage bent at a substantially right angle. The cap (4) includes a stopper (18) fitted in the upper opening (17) of the vial (5) and a cover (19) for covering and holding the stopper in the upper opening (17).
And a cap body (20) engaged on the cover
Consists of.

Next, a method of using the infusion device (1) having the above structure will be described. In FIG. 1, when the vial (5) is moved relatively closer to the bag (3), the second communication passage (11) slides in the direction of the vial (5), and the communication hole (15) moves to the vial (5). 5) and the inside of the vial (5) and the inside of the bag (3) are in communication with each other. Thus by applying intermittent compression to the bag (3),
The solution in the bag (3) is moved back and forth to the vial (5) to dissolve the drug in the vial (5), and a uniform infusion solution is provided between the infusion device (1), that is, the vial (5) and the bag (3). It is obtained in the connecting container of. In addition, this infusion device (1)
When a C-shaped stopper (not shown) is fitted on the outside of the flange (9) until use, and the fitting and locking state of the first communication passage (8) and the second communication passage (11) is maintained, It is possible to prevent the vial (5) and the bag from moving toward each other and communicating with each other due to some shock.

As described above, the infusion device (1) has a small number of parts, so that the cost is low, and the infusion can be prepared by simply moving the vial side (5) and the bag (3) side relatively. Therefore, it is simple and can be done in a short time.

[0020]

According to the present invention, easy and extremely reliable communication can be obtained, and the number of parts is small and the cost is low.

[Brief description of drawings]

FIG. 1 is a vertical sectional view showing one embodiment of the present invention.

FIG. 2 is a front view including a partial cross section showing a conventional example.

[Explanation of symbols]

1 Infusion device 3 bags (flexible container) 5 drug vials (drug containers) 8 first passage 11 Second passage 15 communication holes

Claims (3)

[Claims] 1. A flexible container having a dissolution liquid or a diluting liquid stored therein, a drug container having a drug stored therein, and a first container communicating with either one of the flexible container and the drug container. A communication passage and a second communication passage that communicates with the other container and is fitted and locked in the first communication passage so as to be slidably fitted in the direction of the one container. An infusion solution which is closed at its end and which is provided with a communication hole on the side wall of the road which is closed by the inner wall of the first communication passage so as to be opened in the one container by sliding toward the one container. apparatus. 2. A flexible container having a dissolution liquid or a diluting liquid stored therein, a drug container having a drug stored therein, a first communication passage communicating with the drug container, and a flexible container communicating with the flexible container. A second communication passage slidably fitted in the first communication passage,
A flange extending outward from the root of the second communication passage on the side of the flexible container, and fitted to the outer peripheral edge of the first communication passage so as to be slidably fitted and locked together with the second communication passage in the direction of the drug container. The second communication passage is closed by the inner wall of the first communication passage so that the second communication passage is closed at the end of the road and can be opened in the medicine container by sliding the passage side wall toward the medicine container. The infusion device according to claim 1, comprising a hole. 3. The second communication passage includes a large-diameter portion communicating with the flexible container, and a small-diameter portion that is integrally reduced in diameter from the large-diameter portion.
A communication which further extends integrally from the small diameter portion, closes the tip, and is slidable along the small diameter portion in the direction of the drug container with the small diameter portion so as to be opened in the drug container and closed by the inner wall of the first communication passage. The infusion device according to claim 2, comprising a plug portion having a hole.