JPH05329181A - Adhesive stretch bandage for medical use - Google Patents

Abstract

PURPOSE:To obtain the subject bandage with well peelability, by a method wherein sticker layers are formed on one side of a ground fablic made of cloth knitted with organic fibers longitudinally at regular intervals, part of a sticker is allowed to permeate into the ground fablic, and these layers are irradiated with radioactive rays, are jointly bridged and are sterilized. CONSTITUTION:For the objective bandage 3, sticker layers 2 are formed on one side of a ground fablic 1 longitudinally at regular intervals and part of a sticker is allowed to permeate into the ground fablic 1. In addition, these sticker layers 2 are irradiated with radioactive rays. In this way, the sticker layers 2 are crosslinked and the whole of the bandage 3 is sterilized. Cloth knitted with organic fibers, the so-called stockinette, is used as the ground fabric 1 and an acrylic, rubber, urethane, or silicone-based adhesive agent is used as the sticker. It is desirable that the adhesive agent made of a gelled polymer containing water is used, if possible. Gamma-rays or electron rays are used as the radioactive rays and these layers 2 are treated so that absorbed doses of 0.5 to 20 Mrad can be irragiated thereon.

Description

Detailed Description of the Invention

[0001]

FIELD OF THE INVENTION The present invention relates to an adhesive stretchable bandage. More particularly, it relates to a sterilized medical adhesive stretchable bandage which is a combination of an organic fiber and an adhesive and has good peelability.

[0002]

2. Description of the Related Art As a medical bandage or bandage for protecting the skin surface, an adhesive bandage has been proposed in which an adhesive layer is provided on the surface of a base material made of cloth or a plastic film. As such an adhesive bandage, a woven fabric or a non-woven fabric which has good breathability to prevent a rash and has a large shrinkability so as to follow bending such as knees and elbows is preferably used.
For example, Japanese Utility Model Publication No. 52-34,384 discloses, as a base material for stretchable plasters, 150-60 in at least one direction.
A substrate having 0% stretchability is disclosed. This base material is a stretchable woven fabric in which both warp and weft yarns are woven. The non-woven fabric of the base material of the non-woven bandage disclosed in Japanese Utility Model Publication No. 55-1,627 is a stretchable non-woven fabric made of nylon, polyester, acetate or the like and having a stretchability of 50 to 500%.

However, among such highly stretchable woven fabrics and nonwoven fabrics, for example, the production of woven fabrics requires the use of special yarns such as spandex and twisted yarns, resulting in high cost. Furthermore, a special loom is required to manufacture a woven fabric having a large stretchability, particularly in the length direction (warp method). On the other hand, in order to obtain the above-mentioned nonwoven fabric, in addition to the step of laminating fibers having rubber elasticity and thermally adhering the fibers to each other, various pretreatments and post-processings are required, and the manufacturing process is complicated and The non-woven fabric is poor in strength.

Moreover, when an adhesive bandage having an adhesive layer formed on the entire surface of such a highly stretchable woven or non-woven fabric substrate is wrapped around an arm or the like, the substrate has a large stretching force. As a result, there is a drawback that the skin feels tightened, pulled, pressed, and the like.

Further, the medical adhesive stretchable bandage must be one that can be used immediately in a sterilized state. However, the conventional product has a problem that when heat sterilized, the adhesive layer is deformed or deteriorated by heating. It was

[0006]

Accordingly, it is an object of the present invention to provide a novel adhesive stretch bandage.
Another object of the present invention is to provide a sterilized medical adhesive stretchable bandage, which is formed by forming an adhesive layer on a stretchable fiber substrate and has good peelability.

[0007]

SUMMARY OF THE INVENTION These objects are to provide a space on one side of a base cloth made of organic fiber knitted cloth,
A medical adhesive stretchable bandage formed by forming an adhesive layer so that a part of the adhesive penetrates into the base cloth, and irradiating the adhesive layer to crosslink the adhesive layer and sterilize the adhesive layer at the same time. To be achieved.

[0008]

The present invention will be described in detail with reference to the drawings. That is, as shown in FIGS. 1 and 2, a pressure-sensitive adhesive layer 2 is formed such that a part of the pressure-sensitive adhesive penetrates into the base cloth 1 with a space on one side of the base cloth 1, and A medical adhesive stretchable bandage obtained by irradiating the agent layer 2 with radiation to crosslink the adhesive layer 2 and at the same time sterilize the entire bandage 3.

The base fabric 1 used in the present invention is a knitted fabric made of organic fibers, and is usually called knitted fabric. As the material thereof, synthetic fibers such as polyamide, polyester, polyacrylonitrile, spandex and vinylon, semi-synthetic fibers such as acetate and rayon, cotton,
There are natural fibers such as silk, hemp, and wool, but synthetic fibers are preferable from the viewpoint of radiation resistance.

Examples of the pressure sensitive adhesive include acrylic pressure sensitive adhesive, rubber pressure sensitive adhesive, urethane pressure sensitive adhesive and silicone pressure sensitive adhesive.

Acrylic pressure-sensitive adhesives are monomers having a low glass transition point that impart tackiness (for example, n-butyl acrylate,
Copolymerization of 2-ethylhexyl acrylate, etc.) with a monomer having a high glass transition point (for example, vinyl acetate, (meth) acrylic acid, styrene, hydroxyalkyl (meth) acrylate, etc.) that gives adhesiveness and cohesive force. The main component is coalescence. In particular, a hydrogel-like copolymer made of a copolymer of hydroxyalkyl (meth) acrylate and other (meth) acrylic acid ester gives excellent results in terms of tackiness and releasability.

Examples of hydroxyalkyl (meth) acrylate include 2-hydroxyethyl (meth) acrylate and 2-hydroxypropyl (meth) acrylate. Other (meth) acrylic acid esters include methyl (meth) acrylate, ethyl (meth) acrylate,
Isopropyl (meth) acrylate, n-propyl (meth) acrylate, n-butyl (meth) acrylate, hexyl (meth) acrylate, heptyl (meth) acrylate, 2-ethylhexyl (meth) acrylate, (meth )
Isononyl acrylate, dimethylaminoethyl acrylate (meth), glycidyl acrylate (meth),
There are tert-butylaminoethyl acrylate and the like. In addition to these, (meth) acrylamide, methylol (meth) acrylamide, maleic anhydride, itaconic acid, vinyl acetate, (meth) acrylonitrile, styrene, vinylidene chloride, (meth) Acrylic acid or the like can also be used.

If necessary, ethylene glycol di (meth) acrylate, propylene glycol di (meth) acrylate, diethylene glycol di (meth) acrylate, dipropylene glycol di (meth) acrylate, glycerol tri (meth) acrylate, methylenebisacrylamide, A polyfunctional monomer such as trimethylolpropane triacrylate, ethylene glycol diglycidyl ether, or polyethylene glycol diglycidyl ether may be added as a crosslinking agent. The blending amount of the cross-linking agent is 5% by weight or less, preferably 0.002 to 1.5% by weight, based on the whole monomer.

Polymerization of these monomers is carried out by a usual polymerization method such as solution polymerization or bulk polymerization. The reaction temperature of the polymerization is 50 to 85 ° C, preferably 60 to 80 ° C.

When carrying out solution polymerization, acetone, benzene, toluene, ethyl acetate, hexane, heptane,
In a solvent such as methanol, ethanol or isopropanol, the monomer concentration is 0.5 to 50% by weight, preferably 5 to 50% by weight.
45% by weight, using a polymerization initiator such as azobisisobutyronitrile or benzoyl peroxide. When the polymerization rate reaches 75-95%, reprecipitate with cold methanol or cold ethanol and then dry under reduced pressure or freeze-dry to recover the copolymer, or after completion of the polymerization, dry under reduced pressure, freeze-dry or warm-air dry. And remove the solvent.

As the rubber-based adhesive, natural rubber (polyisoprene), styrene-butadiene rubber, butyl rubber,
Examples include polyisobutylene. These can be used alone or by mixing rubber-based pressure-sensitive adhesives, but can also be used by blending with the acrylic pressure-sensitive adhesive.

Further, a tackifier may be added to these pressure-sensitive adhesives. Examples of the tackifier include rosins, gum rosins, tall oil rosins, hydrogenated rosins, maleated rosins, rosin-based resins such as rosin esters, terpenes-phenol resins, α-pinene-based, β-pinene-based, and limonene-based terpenes. Resins, aromatic hydrocarbon-modified terpene resins, petroleum resins, coumarone-indene resins, styrene-based resins, alkylphenol resins, phenol resins such as rosin-modified phenol resins, and xylene resins. Further, a water retention function-imparting agent may be added. Examples of the water retention function-imparting agent include starch and carboxymethyl cellulose.

The above-mentioned pressure-sensitive adhesive or a pressure-sensitive adhesive composition obtained by blending this with other pressure-sensitive adhesives and / or tackifiers is provided on one side of the base cloth placed on the support at a predetermined interval. Apply. Then, it is placed in a closed container, degassed to permeate the pressure-sensitive adhesive or the pressure-sensitive adhesive composition into the base cloth, and then irradiation is performed to carry out the crosslinking reaction and sterilization at the same time, and the base cloth and the pressure-sensitive adhesive or pressure-sensitive adhesive The agent composition is fixed.

The radiation to be used includes gamma rays, electron rays and the like, but gamma rays are preferable. The irradiation dose is 0.5 to 20 Mrad, preferably 0.7 to 10 M
It is rad. The adhesive or the amount of adhesive applied to the base cloth is 0.05 to 0.5 g / cm ² as solid content,
It is preferably 0.1 to 0.4 g / cm ² .

The adhesive stretchable bandage thus obtained is usually placed in a container by attaching a release paper to the surface of the adhesive layer, but conversely, instead of the base cloth, a gel is applied on the release paper. After this, it may be brought into close contact with the base cloth.

The release paper is a base material coated with a release agent, and the base material is a single film or composite film of various synthetic resins such as polyethylene film and polypropylene film, glassine paper, paper,
There is kraft paper etc. When paper, kraft paper, or the like is used as the base material, sealing is required. Examples of the release agent include silicone type (silicone alone, silicone-organic resin copolymer or blend, etc.) and non-silicone type (polyolefin, alkyd resin, long chain alkyl group-containing resin, fluorine resin, etc.).

[0022]

EXAMPLES Next, the present invention will be described in more detail with reference to examples.

Example 1 100 parts by weight of butyl acrylate and 8.5 parts by weight of 2-hydroxyethyl acrylate were dissolved in 163 parts by weight of benzene, and then 2,2'-azobisisobutyronitrile 0.7 was added. Part by weight was added, and solution polymerization was carried out at a temperature of 60 ° C. for 5 hours. The polymerization rate at this time was 85%. After completion of the reaction, the reaction solution was cooled to 0 ° C., then filtered, reprecipitated with cold ethanol, and dried under reduced pressure.

Water was added to the copolymer thus obtained.
After containing 0% by weight, it was applied to a knitted fabric having a width of 3.5 cm at intervals of 3 cm, and applied over 500 cm at regular intervals at a basis weight of 0.3 g / cm ² .
Then, after putting in a closed container, deaeration and partially permeating the pressure-sensitive adhesive into the base cloth, a release paper coated with silicone on a polyethylene sheet having a thickness of 80 μm is attached to the surface of the pressure-sensitive adhesive layer, and gamma rays ( Cobalt 60) 1.5 Mrad
Crosslinking was performed by irradiation, and the base cloth and the adhesive were fixed to each other, and sterilization was completed at the same time to obtain a medical adhesive stretchable bandage.

Example 2 100 parts by weight of butyl acrylate, 15 parts by weight of 2-hydroxyethyl methacrylate, 50 parts by weight of starch and 0.7 parts by weight of 2,2'-isobisisobutyronitrile were added to 800 parts of a 70% tetrahydrofuran aqueous solution. It was dissolved in 1 part by weight and solution polymerization was carried out at 60 ° C. for an hour. The polymerization rate at this time was 90%. After the reaction is completed, the reaction solution is heated
The mixture was cooled to room temperature, filtered, filtered, reprecipitated with cold ethanol, and dried under reduced pressure.

Water was added to the copolymer thus obtained.
After containing 5% by weight, a release paper coated with silicone on a polyethylene sheet with a thickness of 80 μm is attached to the surface of the adhesive layer, and gamma rays (cobalt 60) of 1.5 M are applied.
Cross-linking was performed by radiating rad, and the base cloth and the adhesive were fixed, and sterilization was also completed to obtain a medical adhesive stretch bandage.

Example 3 100 parts by weight of butyl acrylate, 20 parts by weight of 2-ethylhexyl acrylate, 60 parts by weight of starch and 2,2
'-Asobisisobutyronitrile 0.7 parts by weight, 50
% Tetrahydrofuran solution, and solution polymerization was carried out at 65 ° C. for an hour. The polymerization rate at this time was 89%. After completion of the reaction, the reaction solution was cooled to 0 ° C., then filtered, reprecipitated with cold ethanol, and dried under reduced pressure.

Water was added to the copolymer thus obtained.
After containing 0% by weight, release paper coated with silicone on a polyethylene sheet with a thickness of 80 μm is attached to the surface of the adhesive layer, and gamma rays (cobalt 60) of 1.3 M are applied.
Crosslinking was performed by radiating rad, and the base cloth and the adhesive were fixed to each other, and sterilization was completed at the same time to obtain a medical adhesive stretchable bandage.

Example 4 The physical properties during use of the adhesive medical elastic bandages, ordinary bandages, and bandages obtained in Examples 1 to 3 were examined, and the results shown in Table 1 were obtained. It was

[0030]

[Table 1]

[0031]

EFFECT OF THE INVENTION The medical adhesive stretchable bandage according to the present invention is an adhesive that allows a part of the adhesive to penetrate into the base cloth at a certain interval on one side of the base cloth made of organic fiber knitted cloth. Since the layer is formed and the pressure-sensitive adhesive layer is irradiated with radiation to hang the pressure-sensitive adhesive layer and at the same time the entire bandage is sterilized, even if the bandage partially extends at each part of the body during use. Since the part without the adhesive layer is mainly stretched, the adhesive layer is not affected so much, and the adhesive layer is bonded to the base fabric at the same time as cross-linking, so there is no fear of falling off.

When a water-containing gel adhesive is used as the adhesive, it does not cause discomfort during peeling and has good removability, even though it has good adhesiveness to the skin, and is safe and It does not change with time and is soft. Further, since it is sterilized by radiation, there is no problem such as generation of mold.

[Brief description of drawings]

FIG. 1 is a perspective view of a medical adhesive stretch bandage according to the present invention.

FIG. 2 is a sectional view taken along the line AA of FIG.

[Explanation of symbols]

 1 ... Base cloth, 2 ... Adhesive layer, 3 ... Elastic bandage.

 ─────────────────────────────────────────────────── ─── Continuation of the front page (72) Inventor Toyoaki Suzuki 56 Imaiuecho, Nakahara-ku, Kawasaki-shi, Kanagawa Fuji Mori Kogyo Co., Ltd.

Claims (4)

[Claims] 1. A pressure-sensitive adhesive layer is formed on one side of a base fabric made of a knitted fabric of organic fibers so that a part of the pressure-sensitive adhesive penetrates into the base fabric, and the pressure-sensitive adhesive layer is formed. A medical adhesive stretchable bandage obtained by irradiating with radiation to crosslink the adhesive layer and sterilizing the adhesive layer at the same time. 2. The medical adhesive stretchable bandage according to claim 1, wherein the adhesive is made of a hydrogel polymer. 3. The medical adhesive stretchable bandage according to claim 1, wherein the radiation is a gamma ray or an electron beam. 4. The medical adhesive stretchable bandage according to claim 1, which is irradiated with 0.5 to 20 Mrad of radiation.