JPH05123398A - Throat protection inhalation agent and inhalation instrument - Google Patents

Abstract

PURPOSE:To provide a mucous membrane protection drug which has a disease treatment effect and a phlegm effect together with a basic treatment effect and does not have side effects at all, by conducting inhalation by making a water-soluble liquid whose primary ingredient is calcium, spraylike, making the ingredient adsorb harmful substance and pollen or the like attached to the mucous membrane of a respiratory organ, and discharging it to the outside of a body. CONSTITUTION:The spraylike inhalation of a water-soluble liquid inhalation drug 1 whose primary component is calcium, is conducted, for example, by means of a spray type inhaler 2 with a folding cover 3. The solution is attached to the mucous membrane of a respiratory organ by becoming minute particles, and as the solution is strong, it retains the nature of calcium as it is, and adjoining harmful substance such as alkene is made to be attached to the solution, and the substance becomes phlegm and is discharged simply to the outside of a body by means of coughing that is the natural reaction of the living body. Calcium carbonate in the solution is comparatively hard to be absorbed into the body, thus as soon as it is attached to the mucous membrane, it adsorbs harmful substance, and conducts the action of carrying it out of the body.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION The present invention relates to symptomatic therapeutic agents for sore throat caused by waste gas from automobiles, bronchitis caused by living in a pollution zone, bronchial senso, and hay fever, and their supplements. As a therapeutic treatment,
In addition, the present invention relates to an inhalant for protecting mucous membranes and an inhaler which have all the effects such as a fundamental therapeutic agent with physical constitution improvement.

[0002]

2. Description of the Related Art Conventionally, sympathomimetics such as adrenaline as a symptomatic agent for bronchial sengoku, hay fever, etc. have the drawbacks that they are not long-lasting, their effects gradually decrease with use, and their side effects are large. .. In addition, even xanthine derivatives only suppress seizures, have no improving effect, and have side effects. Antihistamines are said to have no therapeutic effect by themselves. Steroids are only effective as symptomatic treatments, and are side effects because they are hormones. Regarding desensitization therapy as a fundamental treatment method, it takes a long time to identify the causative substance, it is not always effective for all people, the therapy itself also takes a long time, and it is a symptomatic treatment. Because it has no effect
There was no choice but to rely on other drugs, and other physical condition improvement treatments had the same content.

[0003]

Among the conventional drugs of the same kind, drugs that control symptoms such as cough, runny nose, and sputum are used. These symptoms are harmful substances such as allergens in the living body. It is a defense reaction to protect yourself from
Controlling these things will lead to an imbalance in the body, causing side effects. In addition, there is a problem in that by suppressing cough and runny nose, the period in which harmful substances such as allergens adhere to the body is prolonged, and after the drug effect is lost, the symptoms worsen. Many people are not able to identify allergens even with regard to the radical treatment method.
More than one substance may be involved, and there was no effective therapy for all.

The present invention relates to causative substances such as allergens,
For example, the organ mucous membrane to which harmful substances such as soot in the air, dust in the room, and pollen are attached is supplemented with components that promote the discharge of these substances, and the harmful substances are attached to the components. Since this component has an action as a sooting agent that makes tan a silky, low-viscosity substance, it immediately discharges harmful substances out of the body along with cough and tan, which are the original functions of the living body. This work is effective for most people because there is no individual difference. In this ingredient, a substance with immediate effect,
By distributing a slow-acting substance, the mucous membrane's ability to discharge harmful substances is enhanced, and the symptomatic treatment effect
It is an object of the present invention to provide a mucosa-protecting inhalant having both simple and fundamental therapeutic effects and no side effects, and a device for effectively inhaling this.

[0005]

In order to achieve the above-mentioned object, the present invention attaches harmful substances such as allergens,
As a substance to be carried out of the body, an inhalant composed of an aqueous solution containing calcium as a main component is carried out by an inhaler suitable for inhaling this component.

As an inhalant, calcium carbonate, which is considered to be relatively difficult to be absorbed in the body, has a ratio of 70 to 80%, and calcium phosphate, which is considered to be relatively absorbed in the body, is 10 to 20%, Other calcium,
An aqueous solution prepared by dissolving a powder having a particle diameter of 0.1 micron or less and containing 10 to 20% of other components is atomized into a respiratory organ such as nostrils, throat and bronchi. Concentration is 10
About 0 g (10%) of the powder is very effective for 0 cc of water.

Since the particle size of the jetted liquid is as large as several microns to several hundreds of microns, the aqueous solution has a high drop rate. Therefore, inhalation can be performed by a normal inhaler, but can be performed in an effective manner by using a dedicated inhaler with a cover. In a dedicated inhaler, a cover covering the nose and mouth is attached to the inhaler in order to prevent the drop of the ejected medicine from adhering to clothes or the like and to prevent the drug solution from being unnecessarily diffused. A fold-back part is attached to the part where the cover comes into contact with the face to prevent leakage of the solution. Vent on the side opposite the face to facilitate inhalation. The entire cover has a flexible structure, can be bent back and forth, left and right, and the connecting part with the inhaler can freely rotate and the direction of the spout can be changed by 360 degrees. A cover provided with a connecting ring may be attached so that the cover can be easily attached and detached.

As a cover of another structure, the connection part is folded back to prevent the solution from leaking, and a vent is provided on the side opposite to the face to facilitate inhalation, and a curved trumpet type hard plastic. The inhaler can be kept horizontal even if the posture is changed and the inhaler is changed by using a rotating structure for the two joints and a rotating structure for the inhaler mounting part. A cover with a connecting ring is convenient so that the inhaler can be attached and detached.

Further, as the inhaler, a pressure vessel (spray) type which can cope with an emergency is convenient.
The top of the spray container is equipped with a connection ring receiver for attaching the cover, and the structure allows the cover to be easily attached and detached, so that the size can be reduced, it can be carried, and treatment can be immediately performed in an emergency. The cover is attached to the container, the folded portion is placed on the face, and the head of the spray is pressed through the ventilation hole to inhale. Since the cover and the inhaler can be separated, it is convenient to carry, you can easily inhale anywhere, and you do not have to soil your clothes.

As another inhaler, in the case of a rubber ball pressurizing mist blow type inhaler, similarly, by providing a receiving portion for the connecting portion of the cover, the cover can be mounted and effectively Inhalation can be performed. In this case, the drug solution is not disposable but can be packaged in powder, packaged in concentrated solution, in tubes, etc., and can be diluted to a predetermined concentration in a container, which is economical. It is also portable and convenient.

As another inhaler, a mist blow type inhaler is provided with a receiver for mounting a cover, so that the cover can be easily mounted and inhalation can be performed. In this case, a sanitary problem occurs unless the disposable type is used. A plastic disposable mist-type inhaler is filled with a drug solution, and a receiver for connecting a cover is provided on the upper part, the cover is attached, and the head of the mist-blow is pushed through the ventilation port for inhalation.

As another inhaler, a nebulizer type inhaler is provided with a cover mounting receiver, and the cover can be easily mounted for inhalation. In this case, too, if not thrown away, a sanitary problem will occur. It can be easily assembled by enclosing the drug solution in a plastic disposable atomizer, providing a cover mounting receiver on the upper part, and setting the connecting ring of the cover. Inhalation is performed by pushing the lever of the atomizer through the ventilation port.

As another inhaler, an inhaler utilizing the fumes of an electric air compressor can also be used in the case of this chemical solution. On top of the same inhaler,
A cover connection ring mounting receiver is provided, and the cover is mounted for inhalation. In this case, the drug solution is a powder sachet,
It is economical because it can be used by diluting the concentrated solution into tubes, putting it in tubes, etc.

[0014]

When inhaled with the solution or device constructed as described above, the solution becomes fine particles and adheres to the mucous membrane of the respiratory tract, but since it is a concentrated solution, it has the property of calcium as it is. , Harmful substances such as allergens in the vicinity are adhered to the solution, and are simply excreted out of the body by cough which is a natural reaction of the living body. Of the solutions, calcium carbonate is relatively difficult to be absorbed into the body, and therefore has a strong action of adsorbing harmful substances immediately after adhering to the mucous membrane and carrying them out of the body. Therefore, it has an immediate and symptomatic effect. On the other hand, calcium phosphate has a high absorption rate in the body, but when harmful substances such as allergens that enter the body later adhere to the mucous membrane, they are immediately supplied from the body to the mucous membrane and adsorb the harmful substance. And carry it out of the body. Therefore, it has a fundamental therapeutic effect.

When harmful substances such as allergens frequently adhere to the mucous membrane of the respiratory organs, calcium in the mucous membrane is used, calcium deficiency occurs, nasal discharge and sputum become highly viscous, and nasal congestion and congestion occur. By inhalation of the drug solution of the present invention, calcium is replenished, stuffy nose, stuffiness is resolved, normal flow of nasal discharge from the nose to the throat, healthy flow of bronchus to the trachea and throat is smooth. Is carried out, and the Kyotan action works.

[0016]

EXAMPLES Examples will be described with reference to the drawings. FIG. 1 shows an example in which a spray type inhaler 2 is attached to a folding cover 3 via a connecting ring 4 and used. The foldable cover 3 is a bellows,
It can be folded. The part in contact with the face is folded back 5 to prevent the solution from leaking, to serve as the liquid reservoir 6 and to have a structure that conforms to the face. On the side opposite to the face, there is a vent hole 8 that allows air to enter, so that it is easy to inhale and the head of the spray can be pressed from there. Inhaler 2
Keep the orientation as it is, 360 with the rotating unit 10.
Can be rotated once.

In FIG. 2, the inhaler 2 is removed from the foldable cover 3 and is folded for convenient carrying.

FIG. 3 shows a cover having another structure. This is where the cover 25 is attached to the receiver 9 of the spray inhaler 2 via the connecting ring 24. The hard plastic cover 25 has a trumpet-shaped curved structure, and includes two rotating portions A22 and B23 that rotate 360 degrees. The part that comes into contact with the face is folded back 19, and also serves as a liquid pool 20 for preventing liquid leakage, and
The structure fits your face. Vent 2 on the side opposite the face
Since it is 1, air can be inhaled easily, and the head of the spray can be pressed. By rotating the rotating part A22 and the rotating part B23, the inhaler can be kept horizontal even if the posture is changed.

In FIG. 4, the rotating portion A2 of the cover 25 is shown.
2 shows that the rotating portion B23 is rotated and the posture is changed to perform inhalation. In FIG. 4, the upper half of the body is lying down for inhalation, but since the inhaler 2 is kept substantially horizontal, the inhalation can be performed without any trouble.

In the embodiment shown in FIG. 5, by connecting the receptacle 9 of the spray type inhaler 2 containing the solution 1 to the connecting ring 4, the foldable cover 3 is attached and inhalation is performed. It is an example of use. When the folded head 5 is applied to the face and the spray head 7 is pressed from the open ventilation hole 8 to eject the solution 1 in the form of a spray, and at the same time breathing in, air enters from the ventilation hole 8 and inhalation is performed. it can. The liquid medicine that has not been inhaled through the nose and fell down hits the folding back 5 and accumulates in the liquid reservoir 6, so that clothes or the like are not soiled. Since the inhaled solution has large particles and a large specific gravity, the falling speed is fast, and the lung is simplified, and if it is represented by two alveoli, the lower part of the nasal cavity, oral cavity, bronchus, and alveoli indicated by diagonal lines. Although the portion 11 of is in contact with the chemical liquid, the upper portion is relatively less exposed to the chemical liquid.

In order to compensate for this, it is necessary to change the posture for inhalation. In the embodiment shown in FIG. 6, therefore, inhalation is performed with the upper body lying down. In this case, the foldable cover 3 is bent downward, and the rotating unit 10 is turned upside down by 180 degrees. In this state, even if the face is turned downward, the inhaler is kept horizontal and inhalation is possible. In FIG. 6, the inhaler 12 of a rubber ball pressurizing type is used for inhalation. In this case, the liquid reservoir 6 is near the inhaler. The rubber ball 13 is projected rearward from the vent hole 8 and connects the cover and the inhaler by the connection ring 4. In this case, the nasal cavity, the oral cavity, the bronchus, and the like come into contact with the drug solution at 11 parts.

In addition to this, in order to spread the drug solution to each part of the nasal cavity, oral cavity, bronchus, etc., (1) lie on the upper body with the right side up and inhale (2) lie with the left side up Inhalation, (3) Inhalation with the upper body on the back, etc. While changing the posture, and in each posture, take a breath from the mouth, close the mouth, take a breath from the nose, etc.
It is necessary to change the method and perform inhalation. This is because the particle size of the chemical liquid is large and the dropping speed is high. In the embodiment shown in FIG. 7, the user is inhaling with his right side up and his upper body lying down. Only 11 parts come into contact with the chemical solution. In this case, the cover 25 is used, the rotating part B23 is rotated 90 degrees to keep the inhaler horizontal, and the disposable mist-blown inhaler 14 is attached to the receiver 9 by the connecting ring 25, and the vent 21 The head 15 of the inhaler is pressed to perform inhalation. In this case, the liquid pool 20 is on the left side of the cover 25.

In the embodiment shown in FIG. 8, the user is inhaling with his left side up and his upper body lying down. It is the portion 11 that is in contact with the chemical solution. In this case, the cover 25 is used and the rotating portion B23 is rotated 90 degrees to perform suction.

In the embodiment shown in FIG. 9, the disposable atomizer type inhaler 16 is attached to the folding cover 3 by the connecting ring 4 and the upper half of the body is placed on the back for inhalation. In this case, when the foldable cover 3 is bent downward with the inhaler left as it is and the body is laid on its back, the inhaler is in a horizontal state and inhalation is possible. The handle 17 of the sprayer is pushed through the vent hole 8 to introduce air into the sprayer. Further, the lever 18 is pulled to eject the chemical solution. It is only 11 portions where the drug solution comes into contact with the nasal cavity, oral cavity, bronchus and the like.

[0025]

EFFECTS OF THE INVENTION Since the present invention has the operation and configuration as described above, it has the following effects.

Those who have bronchitis or bronchitis, who have a sore throat or nose, or who have a professional respiratory injury due to waste gas, and hay fever caused by living in a pollution zone. As a treatment method for people, by inhaling an inhalant containing calcium as a main component, which has a function of adsorbing harmful substances such as allergens, which are the causative substances, it is possible to use natural agents such as cough, sputum, and runny nose. Using physical strength, symptomatic effect, that is, these harmful substances,
It can be immediately discharged outside the body to relieve symptoms.

Further, by inhaling the medicinal solution into the nose, the nasal discharge has a low normal viscosity, and the flow of the nasal discharge from the nose to the throat can be maintained. In addition, by inhaling the drug solution into the bronchi,
It has a low viscosity, and it has a
The flow of sputum to the bronchi, trachea, and throat is restored, eliminating the stagnation that can interfere with treatment.

When a harmful substance such as an allergen enters the body after inhaling the drug solution, the calcium content once absorbed from the respiratory mucous membrane is immediately supplied from the body to the mucous membrane to adsorb the harmful substance. And discharge it out of the body. By this action, the symptom is relieved, and by repeating this, a fundamental therapeutic effect is produced and a strong constitution capable of counteracting allergen can be obtained.

In order to effectively inhale the liquid medicine having a large particle size of spray particles and a large specific gravity, it has a fold in the face-contact portion, has a vent hole in the rear portion, and has a liquid pool of the liquid medicine that has fallen without being inhaled. With a part, covering the nose and mouth, bendable,
By attaching a foldable cover to the inhaler and performing inhalation, the leakage of inhaled medicine is suppressed, the dirt of clothes etc. is suppressed to a minimum, and the posture at the time of inhalation is changed to supine, lying down, sideways, etc. As a result, the inhaled drug can be spread to all parts of the respiratory organs.

In order to improve the operability of the inhaler,
It is effective to attach a transparent cover made of hard plastic to the inhaler so that the other side of the cover can be seen through. The face-contact part is folded back, the lower part is provided with a liquid pool part, the rear part is provided with a ventilation port, and two curved rotary parts, that is, a rotary part A and a rotary part B are provided. Even if you change your posture to supine, lying down, sideways, etc., you can inhale and spread the inhaled drug to all parts of the respiratory organs.

Further, by attaching a receiver of the connecting ring to a portable spray inhaler containing pressure gas,
Either of the two types of covers can be attached, and inhalation can be easily performed anytime and anywhere. By the cover, it is possible to prevent unnecessary diffusion, and to spread the drug solution to each part of the respiratory organ by inhaling by changing the posture without injuring clothes and performing effective inhalation.

Further, a rubber ball pressurization type mist blow type inhaler is provided with a connection ring receiver, and by attaching a cover of any one of the two types, it can be inhaled anytime anywhere as a reusable portable inhaler. Becomes The cover makes the inhalation of the medicinal solution effective, and the medicinal solution can be spread to each part of the respiratory organ by changing the posture and inhaling, and it is economical because the medicinal solution is replenished.

Further, a disposable atomizer type inhaler is provided with a receptacle for a connecting ring, and a cover for either of these two types is attached, so that it is less irritating by gas and more urgent inhalation than the spray type. It can be used immediately, is hygienic because it is disposable, and can be used as a relatively inexpensive inhaler that can spread the drug solution to each part of the respiratory organ by inhaling while changing the posture.

Furthermore, in a disposable nebulizer type inhaler,
Compared to the spray type, by using a cover connection receiver and attaching one of the two types of covers, gas is not used, so there is less irritation, and it is convenient because you can spray with one touch, and the posture By changing and inhaling, it can be used as an inhaler that can spread the drug solution to each part of the respiratory organ.

By attaching either of the two types of covers to the electric air compressor type inhaler, the leakage of the liquid medicine is small, and the liquid can be delivered to the respiratory part by inhaling while changing the posture. It can be used as an economical inhaler that can be spread over and can be refilled with a liquid medicine.

[Brief description of drawings]

FIG. 1 is a perspective view of a folding cover attached to a spray inhaler.

FIG. 2 is a side view showing a state in which the folding cover is folded.

FIG. 3 is a side sectional view of the cover attached to the spray inhaler.

FIG. 4 is a side view in which the cover is attached to an electric air compressor type inhaler and the upper half of the body is lying down to perform inhalation.

FIG. 5 is a side cross-sectional view in which a folding cover is attached to the spray inhaler to perform inhalation.

FIG. 6 is a side cross-sectional view of a rubber ball pressurizing inhaler with a folding cover attached and the upper half of the body lying down to perform inhalation.

FIG. 7 is a side cross-sectional view in which a cover is attached to the mist-blown inhaler and the upper body is laid sideways for inhalation.

8A and 8B are a front perspective view and a cross-sectional view in which a cover is attached to a mist-blowing type inhaler, and the upper body is laid down to perform inhalation.

FIG. 9 is a side cross-sectional view in which a cover is attached to the nebulizer type inhaler and the upper half of the body is placed on the back for inhalation.

[Explanation of symbols] 1 inhalation drug 26 electric air compressor type 2 spray type inhaler inhaler 3 foldable cover 4 foldable cover connecting ring 5 foldable cover fold part 6 foldable cover liquid pool part 7 spray head Part 8 Folding type cover vent 9 Receiving part 10 Folding type cover rotating part 11 Inhalation solution 12 Rubber ball pressure type inhaler 13 Rubber ball 14 Mist blow type inhaler 15 Mist blow type inhaler head 16 Atomizer type inhaler 17 Atomizer type inhaler Vessel handle 18 Nebulizer type inhaler lever 19 Cover folding part 20 Cover liquid collecting part 21 Cover vent 22 Cover rotating part A 23 Cover rotating part B 24 Cover connecting ring 25 Cover

[Procedure amendment]

[Submission date] January 4, 1993

[Procedure Amendment 1]

[Document name to be amended] Statement

[Name of item to be corrected] 0002

[Correction method] Change

[Correction content]

[0002]

Conventionally, bronchial asthma, such as adrenaline as symptomatic therapy agents, such as hay fever, sympathomimetic agent, there is no persistence, gradually decreasing effect due to use, there is a disadvantage that the side effects large It was In addition, even xanthine derivatives only suppress seizures, have no improving effect, and have side effects. Antihistamines are said to have no therapeutic effect by themselves. Steroids are only effective as symptomatic treatments, and are side effects because they are hormones. Regarding desensitization therapy as a fundamental treatment method, it takes a long time to identify the causative agent, and
Since it is not always effective for all people, the treatment itself takes a long time, and there is no immediate effect as a symptomatic treatment, it is unavoidable to resort to other drugs, and other constitution improving treatments have similar contents. Met.

[Procedure Amendment 2]

[Document name to be amended] Statement

[Name of item to be corrected] 0022

[Correction method] Change

[Correction content]

In addition to this, in order to spread the drug solution to each part of the nasal cavity, oral cavity, bronchus, etc., (1) the upper half of the body is laid on its right side and inhaled. (2) Similarly, lie on your left side and inhale. (3) Inhale with your upper body on your back. Inspire through your mouth, close your mouth, inhale through your nose, etc.
It is necessary to change the method and perform inhalation. This is because the particle size of the chemical liquid is large and the dropping speed is high. In the embodiment shown in FIG. 7, the user is inhaling with his right side up and his upper body lying down. 11 contact with chemicals
It becomes the part of. In this case, the cover 25 is used, the rotating part B23 is rotated 90 degrees to keep the inhaler horizontal, and the disposable mist-blown inhaler 14 is attached to the receiver 9 by the connecting ring 24 , and the vent 21 The head 15 of the inhaler is pressed to perform inhalation. In this case, the liquid pool 20 is on the left side of the cover 25.

[Procedure 3]

[Document name to be amended] Statement

[Name of item to be corrected] 0023

[Correction method] Change

[Correction content]

In the embodiment shown in FIG. 8, the user is inhaling with his right side up and his upper body lying down. It is the portion 11 that is in contact with the chemical solution. In this case, the cover 25 is used and the rotating portion B23 is rotated 90 degrees to perform suction.

[Procedure amendment 4]

[Document name to be amended] Statement

[Correction target item name] Figure 9

[Correction method] Change

[Correction content]

FIG. 9: Attaching a foldable cover to the nebulizer inhaler,
It is sectional drawing of the side surface which is performing inhalation with the upper half of body lying on his back.

Claims (8)

[Claims] 1. An aqueous solution (1) containing calcium as a main component.
Is sprayed and inhaled, invading from outside the body, nasal cavity,
For the purpose of treatment of bronchial fever, bronchitis, hay fever, etc. by adsorbing harmful substances such as allergens and pollen adhering to the mucous membrane of the respiratory tract such as throat and bronchus to the component and discharging it out of the body A mucosal protective inhalant (1). 2. A fold back (5) is attached to the face-to-face portion, a liquid pool (6) is provided at the bottom, and a vent (8) is provided at the rear,
Foldable type for inhalation, which is provided with a connecting ring (4) that can be flexibly bent in the front-rear direction, left-right direction, and can be connected to a receiver (9) of a connecting part of an inhaler, and the ring part can be freely rotated up, down, left-right Cover (3). 3. A folding structure (19) is attached to the face-contacting part, a liquid pool (20) is provided in the lower part, and a ventilation port (21) is provided in the rear part, and a curved structure, a rotating part A (22), and a rotating part. B (2
With the structure of 3), the suction cover (25) includes a connecting ring (24) that can be bent back and forth and left and right and can be connected to the receiver (9) of the connecting portion of the inhaler, and the ring portion can be rotated vertically and horizontally. .. 4. A spray type inhaler (2) containing pressure gas.
A receiver (9) for attaching a cover is provided on the upper part of the cover, and the foldable cover (3) or the cover (25) is attached to the receiver,
A portable inhaler (2) in which a mucosal protective inhalant (1) is enclosed. 5. A rubber ball pressurizing mist-blowing inhaler (12) is provided with a cover mounting receiver (9) on the upper part thereof, and the folding cover (3) or the cover (25) is attached to the receiver. Put on,
Portable inhaler (12). 6. A disposable mist-blown inhaler (14) is provided with a cover mounting receiver (9) on the upper part thereof, and the folding cover (3) or cover (25) is mounted on the receiver. A portable inhaler (14) in which a mucosal protection inhalant (1) is enclosed. 7. A disposable nebulizer type inhaler (16) is provided with a cover mounting receiver (9) on an upper part thereof, and the folding cover (3) or the cover (25) is mounted on the receiver. A portable inhaler (1) encapsulating a mucosal protection inhalant (1)
6). 8. An inhaler using the fumes of an electric air compressor is provided with a cover mounting receptacle (9), and the folding cover (3) or the cover (2) is attached to the receptacle.
An inhaler for wearing the 5) and for inhaling the mucosal protection inhalant (1).