JPH0489413A - Method for killing drug-resistant spider mite - Google Patents

Abstract

PURPOSE:To obtain an acaricidal composition capable of exhibiting high control effect on spider mite with drug resistance by combinedly using fenpropathrin, fluvalinate or bifenthrin with tetradifon. CONSTITUTION:Fenpropathrin, fluvalinate or bifenthrin [2-methylbiphenyl-3- ylmethyl (z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl-2,2- dimethylcyclopropanecarboxylate] respectively expressed by formula I to formula III as an active ingredient is blended with (B) tetradifon which is an active ingredient at a ratio of the ingredient A (I, II) to the ingredient B of 10:1 to 1:10, preferably 2:1 to-1:2 and wt. ratio of ingredients A+B of 1-80wt.% to provide the objective acaricide capable of retarding or preventing the development of drug resistance of spider mites.

Description

DETAILED DESCRIPTION OF THE INVENTION <Industrial Application Field> The present invention relates to a method for killing drug-resistant spider mites.

<Prior Art> Spider mites that parasitize agricultural crops cause great damage to the crops, so controlling them is essential in maintaining agricultural production at a high level. However, organophosphorus compounds and drug resistance have significantly developed, and acaricides that were effective in the past are now forced to lose their effectiveness.

Under these circumstances, various new acaricides other than those mentioned above are being developed, but not only do these new compounds require a huge amount of cost to develop, but as mentioned above, the spider mites associated with the new compounds are The development of drug resistance in this class is generally rapid.

On the other hand, many acaricidal compositions containing existing compounds have been developed. These active ingredients are advantageous in that they are inexpensive to develop because there is already a lot of data on their toxicity and effects on the environment, and they exhibit synergistic effects. However, these mixed acaricidal compositions do not necessarily have sufficient practical effects, and the technology as a solution to drug resistance has not yet been completed.

<Problems to be Solved by the Invention> An object of the present invention is to provide an excellent acaricide that does not cause the development of drug resistance in spider mites.

<Means for solving the problem> As a result of various studies in view of the above situation, the present inventor has found that
We have completed the present invention by discovering that the following active ingredients can be used in combination without worrying about drug resistance, as each active ingredient is highly effective against spider mites that have developed drug resistance. .

That is, the present invention provides α-cyano-3-phenoxybenzyl 2 represented by the formula (a).
, 2,3,3-tetramethylcyclopropanecarboxylate (hereinafter referred to as "fenpropathrin"), α-cyano-8-phenoxybenzyl N
-(2-chloro-" + "IQ -trifluoro-
p-1yl) valinate (hereinafter referred to as "fluparinate J") or 2-methylbiphenyl-8-ylmef(
Z) (iR8)-cis-3-(2-chloro-a,
α,α-hlifluoroprob-1-enyl)-2,2-
The present invention provides dimethylcyclopropane carboxylate (hereinafter referred to as "bifenthrin") and +b) (hereinafter referred to as "bifenthrin").

JP-A-58-19480 discloses that fenbropathrin and tetradifon can be mixed and used as an acaricide.
Although it is described in Publication No. 2, there is no mention of control of drug-resistant spider mites at all in the publication, and the control of drug-resistant spider mites was not recognized.

The drug resistance of spider mites to tetrachlor is widespread in various places, and when fenbropathrin, fluparinate, or bifenthrin is used extensively against these spider mites and against these tetradifon-resistant spider mites, each of them becomes A method for killing drug-resistant spider mites using a composition containing 4,5,4'-tetrachlordiphenylsulfone (hereinafter referred to as "tetradifone") as an active ingredient (hereinafter referred to as the method of the present invention and the method of the present invention). Since the method is highly effective in controlling spider mites that are resistant to each of the active ingredients, it can be said that it is a miticide method that can be used without worrying about the development of drug resistance.In other words, the method of the present invention is a) If spider mites develop drug resistance to fenbropathrin, fluparinate or pifenthrin, ■) Recognition that the acaricidal effect of tetradifon against spider mites will increase, i.e., if spider mites develop a drug resistance to the active ingredient (a) and the Cross-resistance (negative Cr088resistance)
This is based on the discovery that ce).

Spider mites that can be effectively controlled by the method of the present invention include citrus spider mite, apple spider mite, red spider mite, two-spotted spider mite,
Examples include spider mites that parasitize fruit trees, vegetable crops, other crops, garden plants, trees, etc., including false red spider mites and rust mites.

When actually applying the composition used in the method of the present invention,
It can be applied by mixing with a carrier. The commonly used forms are similar to general agricultural chemicals and do not require any special conditions, and can be prepared as emulsions, wettable powders, etc. by methods well known to those skilled in the art.
It can be prepared into any desired dosage form, such as a powder, and can be used for various purposes by using an appropriate shape and carrier.

As the carrier that can be used in the composition used in the method of the present invention, any solid or liquid carrier commonly used for agricultural and horticultural chemicals can be used, and the carrier is not limited to a specific carrier.

Examples include polymers and waxes.

In addition, liquid carriers include water, alcohols, aromatic hydrocarbons, halogenated hydrocarbons, ethers, ketones, esters, nitriles, alcohol ethers,
Examples include aliphatic or cycloaliphatic hydrocarbons, industrial gasoline and petroleum fractions.

In addition, although it has high stability against light, heat, oxidation, etc., if it is especially necessary under extremely oxidative conditions, antioxidants or ultraviolet absorbers, such as Bf(T, phenol derivatives such as BHA, bis- Phenol a conductor or phenyl-
a-naphthylamine, phenyl-β-naphthylamine,
By adding an appropriate amount of arylamines such as a condensate of phenetidine and acetone or benzophenone compounds as a stabilizer, a composition with more stable effects can be obtained.

The mixing ratio of fenbropatrine or fluparinate and tetradifon in these preparations is usually 1021 to 1:10, preferably 2:1 to 1:2 by weight, and the total content of active ingredients in the preparation is is 1 to 80% by weight. The mixing ratio of bifenthrin and tetradifon is usually 1:1 to 1:20, preferably 1:2 to 1:10 by weight.
The total content of active ingredients in the preparation is usually 1 to 80% by weight.

Furthermore, the composition used in the method of the present invention can be used in combination with other acaricides, insecticides, attractants, repellents, fungicides, plant growth regulators, fertilizers, etc. (Applicable pests, usage methods, usage times, etc.) can be expanded.

When applying the composition used in the present invention, the amount of application varies depending on the size of the crop, etc., but the total amount of active ingredients per 10 ares of fenbrobatrin or friparinate and tetradifon is usually 0.3 to 550 g. , preferably 2 to 150 f, and the total amount of bifuentrin and tetradifone is usually 0.8 to 500 f, preferably 2 to 150 g. To spray this, use an emulsion or wettable powder, dilute it with water, and spray it on crops during the period when spider mites appear, usually at a rate of 80 to 20,000 ml per 10 are. Preferably 5
Treat with an application amount of 0 to 5001.

Among the active ingredients used in the method of the present invention, fenbropathrin, fluparinate, and bifuentrin have geometric isomers and/or optical isomers based on asymmetric carbon atoms. All mixtures containing proportions are also included in the present invention.

Practical Examples> The present invention will be explained in more detail below using formulation examples and test examples, but the present invention is not limited to these examples.

First, a formulation example will be given, but the blending ratio of active ingredients, auxiliary ingredients and their addition amounts are not limited to the following formulation examples. In addition, all parts in the formulation examples represent parts by weight.

Formulation Example 1 10 parts of tetradifone is mixed with 10 parts of fue, nbropathrin or fluorine, and toxanone PWS-
Add 66 parts of 46 (Sanyo Kasei Co., Ltd. Oride @ 200C Showa Kagaku Co., Ltd. Keio Haido) and mix thoroughly in an apparatus to obtain each wettable powder.

Formulation Example 2 2 parts of pifentrin and 10 parts of tetradifone were mixed, and to this were added 4 parts of toxanone (same as PWS-46Cn), 10 parts of Toxil GU-N (same as above), and 74 parts of Radiolyte 200 (same as above). 1 part and stir thoroughly to obtain a wettable powder.

Formulation Example 3 Add 10 parts of tetradifone to 10 parts of fenpropathrin or fluparinate, dissolve in 70 parts of xylene, and mix with 10 parts of Trupol 8005X (registered trademark of Toho Chemical Co., Ltd.) to obtain each emulsion.

Formulation Example 4 Add 10 parts of tetradifone to 2 parts of bifenthrin, dissolve in 78 parts of xylene, and mix with 10 parts of Trupol 8005x (same as above) to obtain an emulsion.

Next, test examples will show that the method of the present invention is useful as a method for killing drug-resistant spider mites.

Test Example 1 Ten female adult two-spotted spider mites (a strain showing resistance to tetradifon) were released on a green bean leaf cut into a circle with a diameter of 3 cnI, and after spawning for 24 hours, the adults were removed. This was sprayed with 3 CC of a diluted solution of the emulsion prepared according to Formulation Example 3 at a predetermined concentration using a rotary spraying machine. The treated kidney bean leaves were placed in the center of a kidney bean leaf fixed on agar gel (a circular hole with a diameter of 3 dll was made in the center) and stored at room temperature for 7 days. Calculate the mortality rate of
The synergistic action number was calculated.

Calculated value (LCso) when mixing fenbropatrin and tetradifon = 10 LCso value of fenbropatrin L of tetradifon
The results of Cso values are shown in Table 1.

Test Example 2 When the tetradifone-resistant two-spot spider mites used in Test Example 1 were culled indoors with fenbropathrin 50 times,
A clear reduction in drug sensitivity to fenpropathrin was demonstrated. Eggs obtained using this system in the same manner as Test Example 1 were treated with an emulsion obtained according to Formulation Example 3 diluted with water to a predetermined concentration, and the ovicidal rate of 2 was applied to the predetermined mortar.
The surface action coefficient was determined.

The results are shown in Table 2.

As is clear from Table 2, this strain of two-spotted spider mite showed drug resistance to fenpropathrin, fluparinate, and bifenthrin, and also showed a clear synergistic effect.

Test Example 3 An emulsion prepared according to Formulation Example 8 or 4 was added to a predetermined concentration of green beans planted in pots with a diameter of 93 infested with tetradifon-resistant or fenpropathrin-, fluparinate-, and bifenthrin-resistant two-spotted spider mites. The chemical solution diluted with was sprayed at a ratio of 8ocr:,/8 pots. Before spraying, 7 days after spraying, and 15 days after spraying, the number of adult female two-spotted spider mites parasitic on the plants was investigated.

Control efficiency was calculated from the change in spider mite density using the following formula.

All experiments were conducted using an 8-ward system.

1=1 n: Number of surveys after spraying Cb: Spreading density in untreated area Ca: Density after spraying in untreated area Tb: Spreading density of treated area Ta: Density after spraying in treated area The results are shown in Tables 8 to 5.

<Effects of the Invention> The method of the present invention is extremely effective in killing spider mites such as drug-resistant Sj/N mites, Nisena i 7% mites, Kanzawa spider mites, citrus spider mites, apple spider mites, etc., which occur on fruit trees, tea plants, shiso, flowering trees, etc. The method of the present invention can serve as a technology for delaying or preventing the development of drug resistance in spider mites.

[Brief explanation of drawings]

Figures 1, 2, and 8 are the 8th in Test Example 3, respectively.
The figure was drawn based on the values of control efficiency against drug-resistant spider mites in Table 4, Table 4 qi, and Table 5. The horizontal axis represents the mixed concentration (ppm) of the composition of the present invention, ie, fenbropathrin/tetradifon, fluparinate/tetradifon, or bifenthrin/tetradifon, and the vertical axis represents the control efficiency of drug-resistant spider mites by each mixed drug. Further, the solid line represents the control efficiency against tetradifon-resistant spider mites, and the broken line represents the control efficiency against fenbropathrin-, fluparinate-, and bifuentrin-resistant spider mites. Fluparinate/tetranfone mixed concentration (ppm) chart Bifenthrin/tetradifone mixed concentration (ppm) chart

Claims (2)

[Claims] (1) (a) α-cyano-3-phenoxybenzyl 2,
2,3,3-tetramethylcyclopropanecarboxylate, α-cyano-3-phenoxybenzyl N-(2-
Chloro-α,α,α-trifluoro-p-tolyl)parinate or 2-methylbiphenyl-3-ylmethyl(Z)-(1RS)-cis-3-(2-chloro-3,
3,3-trifluoroprop-1-enyl)-2,2-
A method for killing drug-resistant spider mites using a composition containing dimethylcyclopropanecarboxylate and (b) 2,4,5,4'-tetrachlorodiphenylsulfone as active ingredients. (2) α-cyano-3-phenoxybenzyl 2,2,3
, 3-tetramethylcyclopropanecarboxylate, and 2,4,5,4'-tetrachlordiphenylsulfone as active ingredients.