JP5735335B2 - Insecticide potency enhancer - Google Patents

Description

  The present invention relates to an insecticide efficacy enhancer, an insecticide efficacy enhancement method and an insecticide composition used in the field of agriculture and horticulture.

  Conventionally, in the field of agriculture and horticulture, various insecticides have been used to control pests such as aphids, beetles, damselfly, moths, etc., for example, carbamate insecticides, pyrethroid insecticides, neonicotinoid insecticides, etc. It has been known. These pesticides have a neurotoxic effect on pests and can effectively control pests, but they have persistence and need to be used with due consideration to the effects on the environment and human livestock.

  In recent years, the importance of safety to the environment and human livestock has been emphasized when using insecticides, and there is a tendency to reduce the amount of insecticides used. Various studies have been made. For example, a spreading agent is used in combination so that the insecticide can easily adhere to and penetrate plants and pests (see, for example, Patent Documents 1 and 2). As these spreading agents, various surfactants are mainly used, but it is necessary to use different types and amounts of spreading agents depending on the type of plant. May cause phytotoxicity.

  On the other hand, a technique for attaching a drug to an object without using a spreading agent mainly composed of a surfactant has been studied. For example, a shearable gel containing a drug is formed using a smectite clay mineral. And the technique which adheres a chemical | medical agent to a target object by spraying this gel on a spray target object is known (for example, refer patent document 3).

JP-A-6-329503 JP 2004-300073 A JP 2008-296115 A

However, even if smectite clay minerals are used, the concentration disclosed in the above literature may cause phytotoxicity depending on the type of plant, and if the amount used is reduced, no gel is formed and adhesion to the object is obtained. There is a problem that the effect of the drug is not exhibited.
Therefore, the present invention has been made in view of the above-described problems, and does not cause phytotoxicity on plants, exhibits a high insecticidal effect, and can reduce the amount of insecticide used. An insecticidal efficacy enhancer, a method for enhancing the insecticidal efficacy of an insecticide, and an insecticide composition are provided.

  As a result of intensive studies to solve the above-mentioned problems, the present inventors have combined the insecticide and oxidized cellulose to act synergistically to increase the insecticidal efficacy of the insecticide, and to prevent damage to plants. Thus, the present inventors have found that pests can be safely controlled and have completed the present invention.

That is, the present invention is achieved by the following (1) to (3).
(1) An insecticidal efficacy enhancer for an insecticide, characterized by comprising oxidized cellulose.
(2) A method for enhancing the insecticidal efficacy of an insecticide, which comprises adding the insecticidal efficacy enhancing agent according to (1) to the insecticide.
(3) An insecticide composition comprising the insecticide and the insecticide efficacy enhancer according to (1) above.

  Since the insecticidal efficacy enhancer of the insecticide of the present invention can synergistically increase the insecticidal efficacy of the insecticide, the insecticide composition containing this insecticidal efficacy enhancer prevents the pests that attach to or approach the plant. It can be effectively controlled. Moreover, since oxidized cellulose does not cause a phytotoxicity to plants, an insecticide composition excellent in safety can be provided. Furthermore, since the amount of insecticide used can be reduced, the safety to the environment and human livestock is high, and the product cost can be reduced.

  Hereinafter, the insecticidal efficacy enhancer of the present invention, the insecticidal efficacy enhancing method of the insecticide and the insecticide composition will be described in detail.

The insecticidal efficacy enhancer of the insecticide of the present invention consists of oxidized cellulose.
In the oxidized cellulose used in the present invention, at least a part of the C6 hydroxyl group of cellulose is substituted with a carboxyl group or a metal salt of a carboxyl group. The said oxidized cellulose has the effect | action which increases the insecticidal efficacy synergistically by using together with an insecticide. Examples of the metal salt of the carboxyl group include sodium salt and aminomethylpropanol salt.

  The oxidized cellulose can be obtained by, for example, catalytic oxidation treatment of cellulose with an N-oxyl compound. As the N-oxyl compound, 2,2,6,6-tetramethyl-1-piperidine-N-oxyl (TEMPO) is used. And 4-acetamido-TEMPO can be used (Akira Akai, “TEMPO Oxidized Cellulose Nanofiber”, Polymer, Society of Polymer Sciences, February, Vol. 58, No. 2, p. 90-91. Etc.).

  The insecticide composition of the present invention contains at least the insecticidal efficacy enhancer of the present invention and an insecticide, and is a spray, aerosol, full-injection aerosol, hand pump, liquid, gel, sol Preparations such as preparations, pastes, creams, coatings and ULV preparations.

  The insecticidal efficacy enhancer of the insecticide of the present invention may be appropriately selected according to the effect of enhancing the efficacy against the insecticide to be used, but generally 0.05 to 2 in the insecticide composition. It is preferable to make it contain so that it may become 0.1 mass%, Preferably it is 0.1-1 mass%. If the content of the insecticidal efficacy enhancer is 0.05% by mass or more, it is preferable because the insecticidal efficacy enhancing effect of the insecticide is obtained by the insecticidal efficacy enhancing agent. On the other hand, when the content exceeds 2% by mass, the insecticidal effect is achieved. The fluidity of the agent composition may be lost, and it may not be possible to treat the plant or the like. In addition, if it is the said range, when processing to a plant or a building material, it can fully adhere to a leaf surface, a leaf back, a wall, a pillar, etc., and it does not flow down. Moreover, when spraying using a pump etc., a moderate spray characteristic can be acquired.

Insecticides include, for example, pesticide chrysanthemum extract, natural pyrethrin, praretrin, imiprothrin, phthalthrin, allethrin, transfluthrin, resmethrin, phenothrin, ciphenothrin, permethrin, cypermethrin, etofenprox, cyfluthrin, deltamethrin, bifenthrin, fenvalerate, empens Pyrethroid compounds such as nitrofluophene, methoflutrin, profluthrin, phenpropatriline; organophosphorus compounds such as fenitrothion, diazinon, marathon, pyridafenthion, prothiophos, oxime, chlorpyrifos, dichlorvos; carbamate compounds such as carbaryl, propoxur, mesomil, thiodicarb Oxadiazole compounds such as methoxadiazone; fipro Phenylpyrazole compounds such as sulfene; sulfonamide compounds such as amidoflumet; neonicotinoid compounds such as dinotefuran, imidacloprid, acetamiprid, thiamethoxam, nitenpyram, thiamethoxam; insect growth control compounds such as metoprene, hydroprene, pyriproxyfen; Pyrrol compounds such as chlorfenapyr; isomers or derivatives of these compounds; insecticidal essential oils such as orange oil, mint oil, and benzyl alcohol can be used.
Among the insecticides, it is preferable to use a water-soluble neonicotinoid compound such as dinotefuran, acetamiprid, imidacloprid, nitenpyram, thiamethoxam and the like. By using these water-soluble insecticides, it is not necessary to use surfactants or organic solvents in formulation, and it is highly safe for the environment and human livestock, and may cause phytotoxicity to plants. There is no impact on building materials.

  It is preferable to contain the said insecticide so that it may become 0.0001-10 mass% in an insecticide composition, and preferably 0.001-1 mass%. If the content of the insecticide is within the above range, a sufficient insecticidal effect can be exhibited, the residue on the plant is small, and the safety to human livestock is high.

  Moreover, in the insecticide composition of the present invention, the insecticidal efficacy enhancer of the present invention is contained so that the mass ratio is 1: 1000 to 10: 1 (insecticide: insecticidal efficacy enhancer) with respect to the insecticide. Is preferred. By including an insecticidal efficacy enhancer so as to be in the above range, the synergistic insecticidal efficacy against pests is excellent.

In the insecticide composition of the present invention, as long as the effects of the present invention are exhibited, desired components can be appropriately blended.
For example, pest gate sequestering agents such as machine oil and capric acid ester; antiseptics such as paraoxybenzoic acid ester, dehydroacetic acid, propionic acid, and ε-polylysine; antioxidants such as BHT and BHA; pepper extract, benzoic acid An anti-corrosion agent such as denatonium can be used. In addition, bactericides, nutrients, stabilizers, fragrances, pigments, antifoaming agents, carriers and the like may be used.

  The insecticide composition of the present invention can be obtained, for example, by putting a predetermined amount of the insecticide and the insecticide efficacy enhancer into a carrier such as water, mixing and stirring them, and uniformly dissolving them. Moreover, a solubilizer and an emulsifier can be added as needed, or can be forcibly dispersed and dissolved using a stirring device such as a mixer or a homogenizer.

  The insecticide composition of the present invention may be used as it is, and may be diluted and applied as necessary. When diluting and applying, adjust the dilution so that the pesticide has the desired concentration, and attach it by spraying directly on the target pest or plant as a mist or shower droplet. . Moreover, in order to attach an insecticide composition to a plant, the method of immersing a part of plant may be used.

  The insecticide composition of the present invention includes, for example, agricultural and horticultural pests such as aphids such as peach aphid and cotton aphid, mites such as leafhoppers, leafhoppers, scallops, mites, spider mites; The present invention can be applied to pests; sanitary pests such as flies, mosquitoes and cockroaches; stored pests such as weevil and moth; wood pests such as termites and bark beetles; however, the present invention is not limited to these examples.

  Examples of the plant to which the insecticide composition of the present invention is applied include vegetables such as cabbage, Chinese cabbage, radish, lettuce, carrot, eggplant, tomato, cucumber, pepper, strawberry; potato, sweet potato, taro, yam Legumes such as soybeans, broad beans, kidney beans, peas; fruit trees such as apples, pears, peaches, grapes, lemons, blueberries; roses, pansies, tulips, chrysanthemum, periwinkle, petunia, gerbera, marigold, Flower plants and ornamental plants such as celosia, salvia, verbena, pothos, asiatum, pachira; trees such as azalea, camellia, moxei, sakura, etc., but the present invention is limited by these examples is not.

  EXAMPLES Hereinafter, although an Example demonstrates this invention in more detail, this invention is not limited to an Example.

<Sample preparation>
In accordance with the prescription in Table 1 below, each component was uniformly mixed and stirred with a stirrer to prepare specimens of Examples 1 to 5, Comparative Examples 1 to 6, and Reference Examples 1 to 6. In the case of using oxidized cellulose, other components were dissolved in water in advance, and then the oxidized cellulose was mixed and stirred (about 5000 rpm) with a high-speed stirrer (homomic mixer). When using clay minerals or agar, disperse in water in advance and heat and stir at about 85 ° C (propeller stirrer, about 400 rpm for about 30 minutes), then stop heating and mix other ingredients Stirring (propeller stirrer, about 400 rpm).

<Basic performance evaluation>
Using the above Example 1, Comparative Examples 1 to 3, and Reference Examples 1 to 6, the following basic performance evaluation (Test Examples 1 to 4) was performed.

<Test Example 1: Spray test>
100 mL each of the prepared specimens was filled in a trigger container equipped with “T-650-10 (trade name, discharge amount 0.65 cc / time)” manufactured by Mitani Valve Co., Ltd.
Each specimen was sprayed toward the black board from a position 30 cm before the black board of 0.5 m in length and 0.5 m in width, and the spray pattern was visually evaluated. Evaluation was made as “◯” when sprayed in a fine mist, “Δ” when the particles were coarse and sprayed in the form of water droplets, and “X” when sprayed linearly without being sprayed. The results are shown in Table 2.

<Test Example 2: Adhesion test>
100 mL each of the prepared specimens was filled in a trigger container equipped with “T-650-10 (trade name, discharge amount 0.65 cc / time)” manufactured by Mitani Valve Co., Ltd.
For each specimen, four true leaves of cabbage at the 4th to 6th leaf stage were prepared, and the specimens in the trigger container were sprayed 10 times each to adhere to the whole, and then the dripping of the drug specimen was visually confirmed. Evaluations were made as “◯” for those that did not sag from the treated surface, “Δ” for those that were attached to the treated surface but found to sag, and “x” for those that did not adhere to the treated surface and flowed immediately. The results are shown in Table 2.

<Test example 3: phytotoxicity test>
100 mL each of the prepared specimens was filled in a trigger container equipped with “T-650-10 (trade name, discharge amount 0.65 cc / time)” manufactured by Mitani Valve Co., Ltd.
For each specimen, prepare two true leaves of cabbage at the 4th to 6th leaf stage, a rose seedling (potted plant, height of about 150 mm), and a pansy seedling (potted plant, height of 100 mm). The specimen was sprayed 10 times to adhere to the whole. After cabbage leaves, rose seedlings and pansy seedlings were allowed to stand for 24 hours, the presence or absence of phytotoxicity was confirmed by visual comparison with a non-treated sample (no treatment). Compared with no treatment, “○” indicates that the appearance is almost unchanged, slightly discoloration and deformation occur, but “△” indicates that there is no effect on growth, discoloration and deformation occur, and the portion is withered Was evaluated as “×”. The results are shown in Table 2.

<Test Example 4: Efficacy evaluation test>
100 mL each of the prepared specimens was filled in a trigger container equipped with “T-650-10 (trade name, discharge amount 0.65 cc / time)” manufactured by Mitani Valve Co., Ltd.
Each specimen was prepared by fixing about 10 peach aphids on one true leaf of cabbage at the 4th to 6th leaf stage, and the specimen in the trigger container was sprayed three times. The true leaves of cabbage were left for 24 hours, and the lethality (%) of peach aphid was confirmed by the following formula. In addition, the peach aphid used what was bred in succession in the earth pharmaceutical company. The test was repeated twice. Table 2 shows the result of the average value of two repeated tests.
Fatality (%) = number of dead aphids / number of aphids before test x 100

<Comprehensive evaluation>
Based on the evaluation of Test Examples 1 to 4, as evaluation for usefulness at the time of product, “○” when there is no phytotoxicity and sufficient insecticidal efficacy, and there is no phytotoxicity but insufficient efficacy “ “△” indicates that there is a phytotoxicity and is not useful as a product. The results are shown in Table 2.

From the results in Table 2, it was found that Example 1 had a lethality (efficacy) of 100%, no phytotoxicity to plants, and excellent sprayability and adhesion.
Specifically, the efficacy of the insecticide in Example 1 is enhanced more than combining the lethality of Comparative Example 1 with only the insecticide (dinotefuran) and the lethality of Comparative Example 2 with only oxidized cellulose. all right. Moreover, since the lethality of only polyoxyethylene tristyryl phenyl ether which is a surfactant is 0% as can be seen from Comparative Example 3, the efficacy of the insecticide of Example 1 is enhanced by oxidized cellulose. all right.

  Further, as can be seen from Reference Examples 1 to 4, the clay mineral did not show a synergistic effect of the insecticidal efficacy with the insecticide. Moreover, since the phytotoxicity with respect to a plant body comes out, it is not desirable practically. As can be seen from Comparative Example 1 and Reference Examples 5 and 6, when agar free from phytotoxicity is used, a slight improvement in lethality is observed, but the effect is not sufficient. On the other hand, Example 1 showed a remarkable effect, and it was found that Example 1 has a high synergistic effect between the insecticide and oxidized cellulose.

<Semi-effectiveness evaluation 1>
Using Examples 1 to 3 and Comparative Examples 1 to 4, the following quasi-actual efficacy evaluation 1 was performed.

  An efficacy evaluation test was conducted in the same manner as in Test Example 4 except that the peach aphid that had been bred in succession at Earth Pharmaceutical Co., Ltd. was used instead of the peach aphid collected in the field. The results are shown in Table 3.

From the results in Table 3, it was found that Examples 1 to 3 were superior to Comparative Examples 1 to 4 in lethal efficacy against outdoor peach aphids. It was also found that the lethal efficacy was enhanced as the blending amount of oxidized cellulose was increased.
Specifically, in Comparative Examples 2 and 4 in which no insecticide (dinotefuran) was blended and only oxidized cellulose was blended, there was no lethal effect, but in Examples 1 to 3, blended with oxidized cellulose. As compared with the mortality rate of Comparative Example 1 using only the insecticide (dinotefuran), the mortality rate was improved. Further, as can be seen from Comparative Example 3, since the lethality of the surfactant polyoxyethylene stritylyl phenyl ether alone is 0%, the efficacy of the insecticides of Examples 1 to 3 is enhanced by oxidized cellulose. I found out.

<Quasi-practical evaluation 2>
The following quasi-practical efficacy evaluation 2 was performed using Examples 4 and 5 and Comparative Examples 2, 5, and 6 described above.

  An efficacy evaluation test was conducted in the same manner as in Test Example 4 except that the peach aphid that had been bred in succession at Earth Pharmaceutical Co., Ltd. was used instead of the peach aphid collected in the field. The results are shown in Table 4.

From the results of Table 4, it was found that high mortality was shown in Example 4 (using acetamiprid as an insecticide) and Example 5 (using fenpropatoline as an insecticide) against outdoor peach aphids. .
Specifically, Examples 4 and 5 are more than combined with the lethality of Comparative Example 5 and Comparative Example 6 in which only the insecticide (acetamipride or fenpropatoline) is combined with the lethality of Comparative Example 2 in which only oxidized cellulose is used. Then it was found that the efficacy of the insecticide was enhanced.

  Since the insecticide efficacy enhancer of the present invention has a high insecticidal efficacy enhancing effect, the insecticide composition containing the insecticide efficacy enhancing agent has an excellent insecticidal efficacy and has no phytotoxicity to plants. Since it can safely control pests, it can be used effectively in the field of agriculture and horticulture.

Claims (1)

An insecticidal efficacy enhancer for synergistically enhancing the insecticidal effect of at least one insecticide selected from the group consisting of dinotefuran, acetamiprid and fenpropatoline, characterized by comprising oxidized cellulose.