JPH0482127B2 - - Google Patents

Description

[Detailed Description of the Invention] [Technical Field] The present invention relates to a microbial antifungal agent that is harmless to the human body and can suppress the growth of mold and bacteria and suppress the generation of bad odors. This is related to drugs.

[Prior Art] For example, after sweating, urea contained in sweat, dead cells, etc. remain on underwear, socks, etc., or on the skin.
A portion of it is easily decomposed within a few minutes by the action of bacteria that exist in the natural world, such as in the air, and encourages the growth of new bacteria, mold, etc. Therefore, they emit bad odors such as ammonia odor, causing discomfort to those around them, and may also cause skin damage, such as athlete's foot, ringworm, diaper rash, and other inflammations.

Conventionally, tributyl oxide-based chemicals, for example, have been known as microscopic antifungal agents to inhibit the growth of mold and bacteria, and were put into practical use for deodorizing socks and underwear until the 1950s. Since this chemical is an organic compound containing heavy metals, its use is prohibited because it is permeable and harmful if it comes into direct contact with the human body. Since then, salicylic acid-based chemicals have been used, and several proposals have been made to develop antifungal agents that are harmless to the human body and can inhibit the growth of bacteria. I have not yet found anything that is completely satisfying.

[Problems to be Solved and Means for Solving] In view of the above-mentioned circumstances, the inventors of the present invention particularly aimed to suppress the growth of bacteria caused by substances produced by perspiration, thereby preventing the occurrence of bad odors and reducing skin inflammation. As a result of various studies to obtain a microbial and fungicidal agent that is harmless to the human body and can prevent the above, the purpose of the present invention was achieved by using a mixture of a specific component and an acid as an active ingredient. The present invention was completed based on this discovery.

[Summary of the Invention] That is, the gist of the present invention resides in a microbial and fungicidal agent containing a mixture of saponin and an acid as an active ingredient.

[Structure of the Invention] The antifungal agent of the present invention contains saponin and acid, but the saponin is usually diluted to about 5 to 20 times or 100 to 50,000 times depending on the purpose of use. things are used. The present invention is characterized by the discovery that saponin itself has a growth inhibiting effect and a buffering effect on mold and bacteria; however, when this concentration is too low, it inhibits the growth of mold and bacteria. Even if there is no effect and it is too strong, there is no big change in the effect.

On the other hand, the acid is not particularly limited as long as it is harmless to the human body, such as acetic acid, propionic acid, succinic acid, citric acid, oxalic acid,
Examples include organic acids such as tartaric acid, and inorganic acids such as boric acid, among which acetic acid is particularly preferred. Although these acids are generally known to have a certain degree of bactericidal effect, in the case of the present invention, a more significant bactericidal effect is exhibited by the combination with Yatsuka sap.

The concentration of acid is usually around 3 to 10%, and if this concentration is too low, not only will it not have a sufficient bactericidal effect, but it will also not have a synergistic effect with Yatsuka sap; on the other hand, if it is too high, is unfavorable to the human body. Further, the ratio of acid to Yatsuka sap can be selected depending on the purpose of use.

The microbial and fungicidal agent of the present invention can usually be constituted using an aqueous medium as a base material, but as a base material, for example, an alcoholic medium, a creamy medium, an aqueous gel medium, etc. etc. can be applied. In addition, various other additives and active ingredients other than those of the present invention may be used in combination.

[Effects of the Invention] As described above, according to the microbial and fungicidal agent of the present invention, it is possible to sufficiently suppress the growth of bacteria and stains caused by urea, etc. produced by sweating, dead cells, and the like. Therefore, not only can the bad odor caused by these substances be suppressed, but also skin inflammation and the like can be prevented. Moreover, since the microbial and fungicidal agent of the present invention is harmless to the human body,
For example, it can be applied directly to the skin or impregnated into underwear or socks.
Its field of use is very wide.

[Experimental Examples] Next, the present invention will be explained in more detail using experimental examples, but the present invention is not limited to the description of the following experimental examples unless it exceeds the gist thereof.

Example In order to investigate the growth inhibitory effect on bacteria, the inhibition zone of bacteria that decompose proteins, carbohydrates, fats, etc. was measured on an agar medium.

1 Experimental medium: Using a potato agar medium with Saccharose added,
The above-mentioned bacteria were mixed with this medium, and 15 ml was dispensed into each 9 cm diameter shear dish, and the solidified medium was used as an experimental medium.

2. Test paper A circular filter paper (Toyo Roshi No. 131) with a diameter of 5.5 mm was soaked in saponin, acetic acid, and a mixture of the two for 10 minutes, placed on a dry filter paper, and the excess test solution was removed before use.

3 Experimental method Place test papers treated with the same test solution on the experimental medium at intervals of approximately 3 cm, cover and incubate at 30°C for 12 hours, then measure the diameter of the inhibition circle. Then, the average value in each shear dish was taken and compared with that of each test solution. The same method was repeated twice and the results are shown in Table 1.

Although the size of the inhibition circle differs depending on the type of bacteria, since mixed bacteria were used, the diameter of the smallest inhibition circle (bacterium most resistant to the reagent) was measured for each shear test.

Claims (1)

[Scope of Claims] 1. An antimicrobial agent comprising a mixture of saponin and acid as an active ingredient. 2. The antimicrobial detergent according to claim 1, wherein the acid is an organic acid that is harmless to the human body. 3. The anti-microbial detergent according to claim 1 or 2, wherein the acid is acetic acid.