JPH0470585B2 - - Google Patents
Info
- Publication number
- JPH0470585B2 JPH0470585B2 JP57078105A JP7810582A JPH0470585B2 JP H0470585 B2 JPH0470585 B2 JP H0470585B2 JP 57078105 A JP57078105 A JP 57078105A JP 7810582 A JP7810582 A JP 7810582A JP H0470585 B2 JPH0470585 B2 JP H0470585B2
- Authority
- JP
- Japan
- Prior art keywords
- container
- stirring
- liquid
- sample
- nozzle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000007788 liquid Substances 0.000 claims description 87
- 238000003756 stirring Methods 0.000 claims description 70
- 238000005259 measurement Methods 0.000 claims description 34
- 238000012937 correction Methods 0.000 claims description 27
- 239000003085 diluting agent Substances 0.000 claims description 18
- 239000012085 test solution Substances 0.000 claims description 18
- 238000000034 method Methods 0.000 claims description 17
- 239000000126 substance Substances 0.000 claims description 11
- 239000000243 solution Substances 0.000 claims description 7
- 239000000523 sample Substances 0.000 description 29
- 239000002699 waste material Substances 0.000 description 23
- 238000012360 testing method Methods 0.000 description 22
- 238000004140 cleaning Methods 0.000 description 10
- 238000010586 diagram Methods 0.000 description 4
- 238000007599 discharging Methods 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 238000012545 processing Methods 0.000 description 4
- 238000010790 dilution Methods 0.000 description 2
- 239000012895 dilution Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 238000005086 pumping Methods 0.000 description 2
- 238000012546 transfer Methods 0.000 description 2
- 230000002411 adverse Effects 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 239000012468 concentrated sample Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000012488 sample solution Substances 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Description
【発明の詳細な説明】
本発明は化学分析装置の撹拌装置に関するもの
である。DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a stirring device for a chemical analysis device.
従来より、化学分析装置において、分析すべき
液体試料を容器に収容し、この液体試料をノズル
内に微量吸引し、ノズルを移動させて稀釈液と共
に測定容器に吐出させ化学分析測定を行う方法が
ある。ところで高濃度の試料、反応が緩慢な試
料、または試料が微量な場合にはノズル先端から
吐出する噴射力だけでは混合が不完全となり、正
しい測定値が得られない場合がある。このとき一
般には撹拌機構により試料と稀釈液を十分に混合
して正しい測定値が得られるようにしている。従
来のこのような化学分析装置に採用されている検
液の撹拌方法には、モータに撹拌棒を取付け、測
定容器内で回転する方法、マグネツト撹拌子を測
定容器に入れこの容器の下部より磁力によつて撹
拌子を回転させる方法、測定容器内に空気を送り
込ませ液体中気泡の上昇により撹拌する方法、測
定容器自体を振動または回転することにより撹拌
する方法等目的に応じて各種用いられている。例
えば、特開昭53−111786号公報に開示されている
例では、撹拌棒を撹拌機構に用いている。 Conventionally, in chemical analyzers, chemical analysis measurements have been carried out by storing a liquid sample to be analyzed in a container, sucking a small amount of this liquid sample into a nozzle, moving the nozzle, and discharging it together with a diluent into a measurement container. be. However, in the case of a highly concentrated sample, a sample with a slow reaction, or a small amount of sample, mixing may be incomplete with only the jetting force ejected from the nozzle tip, and accurate measurement values may not be obtained. At this time, a stirring mechanism is generally used to sufficiently mix the sample and diluent to obtain correct measured values. Conventional methods of stirring the test liquid used in such chemical analyzers include attaching a stirring rod to a motor and rotating it inside the measuring container, and placing a magnetic stirrer in the measuring container and applying magnetic force from the bottom of the container. Various methods are used depending on the purpose, such as a method of rotating a stirrer using a screwdriver, a method of stirring by pumping air into the measuring container to cause air bubbles to rise in the liquid, and a method of stirring by vibrating or rotating the measuring container itself. There is. For example, in the example disclosed in JP-A-53-111786, a stirring rod is used as the stirring mechanism.
しかしながら、撹拌棒を用いる方法は、撹拌棒
の回転装置、撹拌棒の上下動装置、撹拌棒を撹拌
位置から洗浄位置へ移動させる装置等が必要とな
り装置全体が複雑で大型化し製造コストが高くな
る欠点がある。またマグネツト撹拌子を用いる方
式では測定容器の下面に磁界を回転させる機能を
常時設置しておかねばならないと共に撹拌子の投
入、洗浄にも注意する必要があり、処理が面倒と
なる欠点がある。さらに、測定容器内の検液中に
空気を送り込む方式では、空気の吐出の仕方によ
つては検液中に細かな気泡が混入し測定値に悪影
響を与えると共に短時間で十分な撹拌を行い難い
欠点がある。また、測定容器自体を回転又は揺動
させる方法も余り大きな撹拌効果を上げることが
できない欠点がある。 However, the method using a stirring bar requires a device for rotating the stirring bar, a device for moving the stirring bar up and down, a device for moving the stirring bar from the stirring position to the cleaning position, etc., making the entire device complicated and large, and the manufacturing cost increases. There are drawbacks. In addition, in the method using a magnetic stirrer, a function to rotate the magnetic field must be always installed on the bottom surface of the measuring container, and care must be taken when inserting and cleaning the stirrer, which has the disadvantage of making the process troublesome. Furthermore, with the method of pumping air into the test liquid in the measurement container, depending on the way the air is discharged, small air bubbles may be mixed into the test liquid, which may have an adverse effect on the measured value, and it may not be possible to stir sufficiently in a short time. There are some serious drawbacks. Furthermore, the method of rotating or rocking the measuring container itself also has the disadvantage that it is not possible to achieve a very large stirring effect.
いずれにしても上述した従来の撹拌方法は撹拌
効果が十分でないので撹拌に要する時間が長くか
かり、必然的に分析時間も長くかかり、分析能率
が低くなるという欠点がある。特にイオン濃度の
測定を行う分析機において、測定容器において検
液の撹拌を行うと、分析能率の低下は甚だしくな
る欠点がある。 In any case, the above-mentioned conventional stirring method has the drawback that the stirring effect is not sufficient, and therefore the time required for stirring is long, which inevitably results in a long analysis time, resulting in low analysis efficiency. Particularly in an analyzer that measures ion concentration, if the test solution is stirred in the measurement container, there is a drawback that the analysis efficiency will be significantly reduced.
本発明の目的は試料および少なくとも稀釈液よ
り成る検液を短時間で撹拌することができ、しか
も撹拌を撹拌専用の容器で行うことにより十分な
撹拌ができると共に検液の撹拌と補正液の測定と
を同時に行うことにより分析能率を向上すること
ができる化学分析装置の撹拌装置を提供しようと
するものである。 The object of the present invention is to be able to stir a test solution consisting of a sample and at least a diluted solution in a short period of time, and to achieve sufficient stirring by using a container exclusively for stirring, as well as to stir the test solution and measure the correction solution. It is an object of the present invention to provide a stirring device for a chemical analyzer that can improve analysis efficiency by simultaneously performing the following steps.
本発明は、液体試料を少なくとも希釈液と混合
して検液を作成し、この検液のイオン濃度を測定
するための化学分析用検液の撹拌方法において、
試料を収容する試料容器と、希釈液を収容する希
釈液容器と、試料と希釈液を移送するためのノズ
ルと、ノズルによつて移送された試料と希釈液と
を混合して作成した検液を撹拌するための撹拌容
器と、撹拌された検液のイオン濃度を測定するた
めのイオン選択電極と参照電極とを有する測定容
器と、測定容器に連通した補正液を収容する補正
液容器とを備え、検液を撹拌している間に、測定
容器に補正液を移送して、撹拌中の検液に関する
補正液のイオン濃度を測定することを特徴とする
ものである。 The present invention provides a method for stirring a test solution for chemical analysis for preparing a test solution by mixing a liquid sample with at least a diluent and measuring the ion concentration of the test solution.
A sample container containing a sample, a diluent container containing a diluent, a nozzle for transferring the sample and diluent, and a test solution prepared by mixing the sample and diluent transferred by the nozzle. a stirring container for stirring the sample solution, a measurement container having an ion selection electrode and a reference electrode for measuring the ion concentration of the stirred test solution, and a correction liquid container communicating with the measurement container and containing a correction liquid. The method is characterized in that, while the test liquid is being stirred, a correction liquid is transferred to a measurement container, and the ion concentration of the correction liquid with respect to the test liquid being stirred is measured.
以下図面を参照して本発明を詳細に説明する。
なお説明を簡明にするため同一部分には同一の符
号を付す。 The present invention will be described in detail below with reference to the drawings.
In order to simplify the explanation, the same parts are given the same reference numerals.
第１図は本発明の化学分析用検液の撹拌方法を
適用する装置の実施例を示す模式的線図である。
ターンテーブル、エンドレスチエーン等により、
液体試料１を収容した試料容器２を試料吸引位置
ａに順次位置決めして搬送する。液体試料１を吸
排するノズル３を、試料吸引位置ａ、撹拌洗浄位
置ｂ、測定位置ｃのそれぞれの位置を経て往復移
動するノズル移送機構４を設ける。撹拌洗浄位置
ｂには逆円錐形に底面を形成した撹拌容器５を配
置し、測定位置ｃには測定容器６を配置する。こ
の測定容器６はモータ７により回転させる。この
測定容器６内にはイオン選択電極８ａ、参照電極
８ｂを挿入し、これら電極は信号処理回路９およ
び表示装置１０に接続する。また測定容器６には
補正液分注用ノズル１１を臨ませ、補正液容器１
３に収容した補正液１２をポンプ１４により測定
容器６に分注できるようにする。稀釈液１５を収
容した稀釈液容器１６をバルブ１７を介してシリ
ンジ１８に連結し、このシリンジをバルブ１９を
介してノズル３に連結する。シリンジ１８のピス
トン１８ａは両矢印方向に適当な駆動機構により
上下動させる。廃液ポンプ２０は、しごきポンプ
で、撹拌容器５内に配設した廃液ノズル２１およ
び測定容器６内に配設した廃液ノズル２２と廃液
容器２３との間に介在させ、これを矢印方向に回
転させることにより、撹拌容器５および測定容器
６内の廃液を共に廃液容器２３に排出することが
できる。しごきポンプ２０と廃液ノズル２１との
間には三方バルブ２５を介挿する。 FIG. 1 is a schematic diagram showing an embodiment of an apparatus to which the method of stirring a test liquid for chemical analysis of the present invention is applied.
With turntables, endless chains, etc.
The sample containers 2 containing the liquid sample 1 are sequentially positioned at the sample suction position a and transported. A nozzle transfer mechanism 4 is provided that reciprocates a nozzle 3 that sucks and discharges a liquid sample 1 through a sample suction position a, an agitation cleaning position b, and a measurement position c. A stirring container 5 having an inverted conical bottom is placed at the stirring cleaning position b, and a measuring container 6 is placed at the measuring position c. This measurement container 6 is rotated by a motor 7. An ion selection electrode 8a and a reference electrode 8b are inserted into the measurement container 6, and these electrodes are connected to a signal processing circuit 9 and a display device 10. In addition, a correction liquid dispensing nozzle 11 is placed facing the measurement container 6, and the correction liquid container 1
The correction liquid 12 contained in the container 3 can be dispensed into the measuring container 6 by the pump 14. A diluent container 16 containing a diluent 15 is connected to a syringe 18 via a valve 17, and this syringe is connected to a nozzle 3 via a valve 19. The piston 18a of the syringe 18 is moved up and down in the directions of both arrows by a suitable drive mechanism. The waste liquid pump 20 is a straining pump, which is interposed between a waste liquid nozzle 21 disposed in the stirring container 5, a waste liquid nozzle 22 disposed in the measurement container 6, and a waste liquid container 23, and rotates in the direction of the arrow. As a result, the waste liquid in the stirring container 5 and the measuring container 6 can both be discharged into the waste liquid container 23. A three-way valve 25 is inserted between the squeezing pump 20 and the waste liquid nozzle 21.
次に第２図に示すフローチヤートをも参照して
本例装置の動作を説明する。先ず瞬時t0において
バルブ１７を開き、シリンジ１８のピストン１８
ａを両矢印の下方向に降下させたシリンジ１８の
上部に稀釈液１５を定量吸引する。ノズル３は試
料吸引位置ａにあり、試料吸引位置ａに停止して
いる試料容器２に収容されている液体試料１中に
ノズル３を侵入させ、次に時刻t1においてバルブ
１９を開きピストン１８ａをさらに降下させ、液
体試料１の設定量をノズル３内に吸引する。次に
ノズル３は上方に移動した後撹拌洗浄位置ｂに移
送される。時刻t2においてピストン１８ａは上昇
しノズル３内の液体試料１と今までシリンジ１８
内に貯留しておいた前述の定量の稀釈液１５を撹
拌容器５内に注入する。この時バルブ１７は閉と
しておく。つづいてピストン１８ａの上下動を一
定回数行うことにより、ノズル３は撹拌容器５内
の検液２４の吸・排動作を繰返し行うことによ
り、検液２４を短時間の間に十分に撹拌すること
ができる。一定回数の撹拌を終了した後、ピスト
ン１８ａが下降しノズル３内に所定量の検液２４
を吸引する。次にノズル３は上昇し、さらに測定
位置ｃに移送される。時刻t3において、ピストン
１８ａが上昇しノズル３内に吸引されている検液
２４を測定容器６の上部に注入する。この注入終
了後バルブ１９は閉とする。モータ７は常時回転
し測定容器６を回転させている。これは短時間で
測定容器６内での検液撹拌を行わせ、かつ後述の
補正液１２による洗浄の撹拌のためにも有効であ
るが必ずしも必要でない。測定容器６に注入され
た検液２４は時刻t4においてイオン選択電極８ａ
および参照電極８ｂで測定され信号処理回路９を
経て表示装置１０に測定値が表示される。次に時
刻t5において廃液ポンプ２０を矢印方向にしご
き、測定を終了した検液２４を廃液ノズル２２か
ら廃液容器２３に排出する。 Next, the operation of the apparatus of this example will be explained with reference to the flowchart shown in FIG. First, at the moment t0 , the valve 17 is opened and the piston 18 of the syringe 18 is opened.
A fixed amount of the diluent 15 is aspirated into the upper part of the syringe 18, which is lowered in the downward direction of the double arrow. The nozzle 3 is at the sample suction position a, and the nozzle 3 is inserted into the liquid sample 1 contained in the sample container 2 which is stopped at the sample suction position a. Then, at time t1 , the valve 19 is opened and the piston 18a is further lowered, and a set amount of liquid sample 1 is sucked into nozzle 3. Next, the nozzle 3 moves upward and is then transferred to the stirring cleaning position b. At time t2 , the piston 18a rises and the liquid sample 1 in the nozzle 3 and the syringe 18
The above-mentioned fixed amount of the diluent 15 stored in the stirring container 5 is injected into the stirring container 5. At this time, the valve 17 is kept closed. Next, by moving the piston 18a up and down a certain number of times, the nozzle 3 repeatedly sucks and discharges the test liquid 24 in the stirring container 5, thereby sufficiently stirring the test liquid 24 in a short period of time. I can do it. After stirring a certain number of times, the piston 18a descends and a predetermined amount of test liquid 24 is deposited in the nozzle 3.
aspirate. Next, the nozzle 3 is raised and further transferred to the measurement position c. At time t 3 , the piston 18 a rises and the test liquid 24 drawn into the nozzle 3 is injected into the upper part of the measurement container 6 . After this injection is completed, the valve 19 is closed. The motor 7 is constantly rotating to rotate the measurement container 6. This is effective for stirring the test liquid in the measurement container 6 in a short time and also for stirring the washing with the correction liquid 12, which will be described later, but is not necessarily necessary. The test liquid 24 injected into the measurement container 6 reaches the ion selective electrode 8a at time t4 .
The measured value is measured by the reference electrode 8b, and the measured value is displayed on the display device 10 via the signal processing circuit 9. Next, at time t 5 , the waste liquid pump 20 is pushed in the direction of the arrow, and the test liquid 24 that has been measured is discharged from the waste liquid nozzle 22 into the waste liquid container 23 .
ノズル３は測定容器６へ検液２４を注入した
後、撹拌洗浄位置ｂへ移動する。この移動終了と
同期して時刻t7およびt8においてバルブ１７，１
９を交互に開閉させ、同時にピストン１８ａを上
下動させ、稀釈液１５を撹拌容器５内にノズル３
より排出する。この稀釈液１５の排出によりノズ
ル３内を洗浄し、撹拌容器５内に貯留した稀釈液
１５によりノズル３の外壁と、撹拌容器５内の洗
浄を行い、一定回数の洗浄後、時刻t9において廃
液ポンプ２０を駆動し廃液ノズル２１より廃液容
器２３内へ排出する。洗浄されたノズル３はさら
に試料吸引位置ａに搬送され、次の試料の吸引に
備える。 After injecting the test liquid 24 into the measurement container 6, the nozzle 3 moves to the stirring cleaning position b. At times t7 and t8 , valves 17 and 1 are synchronized with the end of this movement.
9 alternately open and close, and at the same time move the piston 18a up and down, the diluted liquid 15 is introduced into the stirring container 5 through the nozzle 3.
Emit more. The inside of the nozzle 3 is cleaned by discharging this diluted liquid 15, and the outer wall of the nozzle 3 and the inside of the stirring vessel 5 are cleaned with the diluted liquid 15 stored in the stirring container 5. After a certain number of cleanings, at time t9. The waste liquid pump 20 is driven to discharge the waste liquid from the waste liquid nozzle 21 into the waste liquid container 23. The cleaned nozzle 3 is further transported to the sample suction position a, and is prepared for suctioning the next sample.
本例においては、検液２４を撹拌している間に
補正液の測定を行うことができる。すなわち、時
刻t10においてポンプ１４を駆動し補正液１２を
補正液ノズル１１を経て測定容器６に注入し測定
容器６と電極８ａ，８ｂの検液２４との接液部を
補正液１２で満たし、次に時刻t11において廃液
ポンプ２０を動作させ廃液ノズル２２から廃液容
器２３内に排出する。これを一定回数繰返すこと
により測定容器６と電極８ａ，８ｂの洗浄を行
う。前述のようにモータ７は常時測定容器６を回
転させているので、補正液１２による電極８ａ，
８ｂと測定容器６の洗浄も有効かつ迅速に行われ
る。洗浄終了後、時刻t12においてポンプ１４を
駆動し、新たな補正液１２を測定容器６へ注入
し、時刻t13において電極８ａ，８ｂにより補正
液１２を測定する。先に測定した検液２４の測定
値から補正液１２の測定値を信号処理回路９で減
算して表示装置１０により液体試料１の補正した
測定値を表示する。この補正液による洗浄および
測定中はバルブ２５を大気側に切換え、撹拌容器
５内の検液は排出されないようにする。 In this example, the correction liquid can be measured while the test liquid 24 is being stirred. That is, at time t10 , the pump 14 is driven and the correction liquid 12 is injected into the measurement container 6 through the correction liquid nozzle 11, so that the liquid contact part between the measurement container 6 and the test liquid 24 of the electrodes 8a and 8b is filled with the correction liquid 12. Then, at time t 11 , the waste liquid pump 20 is operated to discharge the waste liquid from the waste liquid nozzle 22 into the waste liquid container 23 . By repeating this a certain number of times, the measurement container 6 and the electrodes 8a, 8b are cleaned. As mentioned above, since the motor 7 constantly rotates the measurement container 6, the electrodes 8a,
8b and the measurement container 6 are also effectively and quickly cleaned. After the cleaning is completed, the pump 14 is driven at time t12 , new correction liquid 12 is injected into the measurement container 6, and the correction liquid 12 is measured by the electrodes 8a and 8b at time t13 . The signal processing circuit 9 subtracts the measured value of the correction liquid 12 from the previously measured measured value of the test liquid 24, and the corrected measured value of the liquid sample 1 is displayed on the display device 10. During cleaning and measurement with this correction liquid, the valve 25 is switched to the atmosphere side so that the test liquid in the stirring container 5 is not discharged.
上述したように試料液体と稀釈液との撹拌は分
注ノズルにより吸排することにより行うため、き
わめて短時間で有効に撹拌することができると共
に撹拌を測定容器とは別個に設けた撹拌専用の容
器で行うため、或る検液を撹拌している間に補正
液の測定を同時に行うことができ、分析能率は非
常に高くなる。さらに、別個に撹拌装置を設ける
必要がないので装置全体が簡易化すると共に小型
になる。 As mentioned above, the sample liquid and diluent are stirred by sucking and discharging them with a dispensing nozzle, so stirring can be done effectively in a very short time, and the stirring is done in a separate container from the measurement container. Therefore, while a certain test solution is being stirred, the correction solution can be measured at the same time, which greatly increases analysis efficiency. Furthermore, since there is no need to provide a separate stirring device, the entire device becomes simpler and smaller.
第３図は本発明の撹拌方法の他の例を実施する
分析機の構成を示す模式的線図である。この例で
は第１図に示す検液２４の撹拌をノズル３の吸排
によらず、撹拌容器５内の検液２４を撹拌棒３１
の回転により行うようにする。すなわち、撹拌棒
３１を歯車３２に枢着し、この歯車３２と噛合す
る歯車３３をモータ３４の駆動軸に枢着する。 FIG. 3 is a schematic diagram showing the configuration of an analyzer implementing another example of the stirring method of the present invention. In this example, the test liquid 24 shown in FIG.
This is done by rotating the . That is, the stirring rod 31 is pivotally attached to a gear 32, and the gear 33 that meshes with the gear 32 is pivotally attached to the drive shaft of the motor 34.
撹拌容器５内にノズル３が液体試料１と稀釈液
１５との混合液を吐出するのに同期してモータ３
４を駆動し歯車３３，３２を経て撹拌棒３１を回
転させて検液２４を撹拌することができる。本発
明においては撹拌専用の容器を設けたため、撹拌
と補正液による洗浄、測定とをほぼ同時に行うこ
とができるので、分析能率は向上する。また、撹
拌は撹拌専用の容器で行うため、短時間で有効に
撹拌することができる。 The motor 3 is activated in synchronization with the nozzle 3 discharging a mixture of the liquid sample 1 and the diluent 15 into the stirring container 5.
4 to rotate the stirring rod 31 via the gears 33 and 32 to stir the test liquid 24. In the present invention, since a container exclusively for stirring is provided, stirring, cleaning with a correction liquid, and measurement can be performed almost simultaneously, improving analytical efficiency. Further, since stirring is performed in a container exclusively for stirring, stirring can be performed effectively in a short period of time.
以上述べたように本発明の化学分析装置の撹拌
装置では、撹拌専用の容器を設けたため、検液の
撹拌能率を向上することができるとともに撹拌動
作と同時に補正液の測定を行うことができ、分析
時間を短縮することができるという効果がある。 As described above, in the stirring device of the chemical analyzer of the present invention, since a container exclusively for stirring is provided, the stirring efficiency of the test liquid can be improved, and the correction liquid can be measured at the same time as the stirring operation. This has the effect of shortening analysis time.
なお、本発明は前述の例に限定されるものでな
く幾多の変更や変形が可能である。例えば上述し
た例では測定容器をモータにより回転させたが、
このようにすることは必ずしも必要でない。さら
に上述した例では１個の廃液ポンプにより撹拌容
器および測定容器から廃液するようにしたが、そ
れぞれ別個の廃液ポンプを用いることもできる。 It should be noted that the present invention is not limited to the above-mentioned example, and can be modified and modified in many ways. For example, in the example mentioned above, the measurement container was rotated by a motor, but
It is not necessary to do this. Further, in the example described above, one waste liquid pump is used to drain liquid from the stirring vessel and the measuring vessel, but separate waste liquid pumps may be used for each.
第１図は本発明の化学分析用検液の撹拌方法を
適用する装置の一実施例を示す模式的線図、第２
図は同じくその動作を説明するためのタイムチヤ
ートを示す図、第３図は本発明の他の例を実施す
る分析機の構成を示す模式的線図である。
１……液体試料、２……試料容器、３……ノズ
ル、４……ノズル移送機構、５……撹拌容器、６
……測定容器、７……モータ、８ａ，８ｂ……イ
オン測定用電極、９……信号処理回路、１０……
表示装置、１１……補正液分注用ノズル、１２…
…補正液、１３……補正液容器、１４……ポン
プ、１５……稀釈液、１６……稀釈液容器、１７
……バルブ、１８……シリンジ、１８ａ……ピス
トン、１９……バルブ、２０……廃液ポンプ、２
１，２２……廃液ノズル、２３……廃液容器、２
４……検液、２５……三方バルブ、３１……撹拌
棒、３２，３３……歯車、３４……モータ。
FIG. 1 is a schematic diagram showing an embodiment of an apparatus to which the method of stirring a test solution for chemical analysis of the present invention is applied, and FIG.
The figure also shows a time chart for explaining its operation, and FIG. 3 is a schematic diagram showing the configuration of an analyzer implementing another example of the present invention. DESCRIPTION OF SYMBOLS 1... Liquid sample, 2... Sample container, 3... Nozzle, 4... Nozzle transfer mechanism, 5... Stirring container, 6
...Measurement container, 7...Motor, 8a, 8b...Ion measurement electrodes, 9...Signal processing circuit, 10...
Display device, 11... Correction liquid dispensing nozzle, 12...
... Correction liquid, 13 ... Correction liquid container, 14 ... Pump, 15 ... Dilution liquid, 16 ... Dilution liquid container, 17
... Valve, 18 ... Syringe, 18a ... Piston, 19 ... Valve, 20 ... Waste liquid pump, 2
1, 22... Waste liquid nozzle, 23... Waste liquid container, 2
4... Test liquid, 25... Three-way valve, 31... Stirring rod, 32, 33... Gear, 34... Motor.
Claims (1)
を作成し、この検液のイオン濃度を測定するため
の化学分析用検液の撹拌方法において、試料を収
容する試料容器と、希釈液を収容する希釈液容器
と、試料と希釈液を移送するためのノズルと、ノ
ズルによつて移送された試料と希釈液とを混合し
て作成した検液を撹拌するための撹拌容器と、撹
拌された検液のイオン濃度を測定するためのイオ
ン選択電極と参照電極とを有する測定容器と、測
定容器に連通した補正液を収容する補正液容器と
を備え、検液を撹拌している間に、測定容器に補
正液を移送して、撹拌中の検液に関する補正液の
イオン濃度を測定することを特徴とする化学分析
用検液の撹拌方法。1 In a method of stirring a test solution for chemical analysis in which a test solution is prepared by mixing a liquid sample with at least a diluent and the ion concentration of this test solution is measured, a sample container containing a sample and a sample container containing a diluent are used. a diluent container for transferring the sample and the diluent; a stirring container for stirring the test solution prepared by mixing the sample and diluent transferred by the nozzle; A measurement container having an ion selection electrode and a reference electrode for measuring the ion concentration of a test solution, and a correction solution container communicating with the measurement container and containing a correction solution, and while stirring the test solution, A method for stirring a test solution for chemical analysis, which comprises transferring the correction solution to a measurement container and measuring the ion concentration of the correction solution with respect to the test solution being stirred.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP57078105A JPS58196461A (en) | 1982-05-12 | 1982-05-12 | Agitation of sample liquid for chemical analysis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP57078105A JPS58196461A (en) | 1982-05-12 | 1982-05-12 | Agitation of sample liquid for chemical analysis |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP29716090A Division JPH03170046A (en) | 1990-11-05 | 1990-11-05 | Method for stirring specimen liquid for chemical analysis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS58196461A JPS58196461A (en) | 1983-11-15 |
| JPH0470585B2 true JPH0470585B2 (en) | 1992-11-11 |
Family
ID=13652601
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP57078105A Granted JPS58196461A (en) | 1982-05-12 | 1982-05-12 | Agitation of sample liquid for chemical analysis |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS58196461A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011108720A1 (en) | 2010-03-05 | 2011-09-09 | Jx日鉱日石金属株式会社 | Positive-electrode active material for lithium ion battery, positive electrode for lithium battery, and lithium ion battery |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2795564B2 (en) * | 1991-10-08 | 1998-09-10 | アロカ 株式会社 | Dilution method for highly viscous liquid |
| JP4203826B2 (en) * | 2003-09-29 | 2009-01-07 | 独立行政法人産業技術総合研究所 | Automatic analysis method and apparatus |
| US8863595B2 (en) | 2007-08-05 | 2014-10-21 | Kuwait University | Sample extraction device |
| JP5850786B2 (en) * | 2012-04-04 | 2016-02-03 | 京都電子工業株式会社 | Automatic titrator |
| JP5789635B2 (en) | 2013-04-26 | 2015-10-07 | 株式会社堀場製作所 | Whole blood blood cell immunoassay device |
| JP6427573B2 (en) * | 2014-07-18 | 2018-11-21 | 株式会社日立ハイテクノロジーズ | Liquid stirring method |
| JP7292195B2 (en) * | 2019-12-06 | 2023-06-16 | 株式会社日立ハイテク | automatic analyzer |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5235693A (en) * | 1975-09-16 | 1977-03-18 | Hitachi Ltd | Automatic analysis apparatus of a wide range of quantitative determinati on |
| JPS5355189A (en) * | 1976-10-29 | 1978-05-19 | Toa Medical Electronics | Diluting device |
| JPS56163744A (en) * | 1980-04-18 | 1981-12-16 | Beckman Instruments Inc | Method and device for mixing sample liquid and diluted liquid |
-
1982
- 1982-05-12 JP JP57078105A patent/JPS58196461A/en active Granted
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5235693A (en) * | 1975-09-16 | 1977-03-18 | Hitachi Ltd | Automatic analysis apparatus of a wide range of quantitative determinati on |
| JPS5355189A (en) * | 1976-10-29 | 1978-05-19 | Toa Medical Electronics | Diluting device |
| JPS56163744A (en) * | 1980-04-18 | 1981-12-16 | Beckman Instruments Inc | Method and device for mixing sample liquid and diluted liquid |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011108720A1 (en) | 2010-03-05 | 2011-09-09 | Jx日鉱日石金属株式会社 | Positive-electrode active material for lithium ion battery, positive electrode for lithium battery, and lithium ion battery |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS58196461A (en) | 1983-11-15 |
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