JPH0449213A - Skin protecting agent composition - Google Patents

Abstract

PURPOSE:To obtain a composition protecting chapped skin in scrubbing and washing, a skin cleaning process, etc., especially chapped skin of hand by combining a specific oily substance as an oily component with a perfluoropolyether in a specific weight ratio. CONSTITUTION:A skin protecting agent composition comprising >=80wt.% total amounts based on whole oily components of an oily substance (e.g. vaseline or solid paraffin) having >=35 deg.C softening point and a value of organic nature/ inorganic nature of >=4 as an oily component and an oily perfluoropolyether in a weight ratio of (10:1) to (1:2). The composition has high effects of protecting skin from scrubbing and washing, a skin cleaning process, etc., excellent feeling in use such as slip and little greasiness.

Description

[Detailed Description of the Invention] [Industrial Application Field] The present invention relates to a skin protection agent, and more particularly, to a skin protection agent for protecting the skin from rough skin (mainly rough hands) during washing, washing the skin, etc. Regarding the composition.

[Prior art and problems to be solved by the invention] Conventionally,
Hand creams are commonly used to protect the skin from roughness caused by water work. Hand creams protect the skin by replenishing sebum lost due to water work, etc., and by adding a moisturizing agent, it replenishes the skin with an appropriate amount of moisture.

However, since conventional hand creams are easily washed away with water, their skin protection effects are not always satisfactory. In fact, many housewives suffer from rough hands due to frequent tasks with water such as cooking and washing. In addition, many hairdressers complain of irritation due to hair dye, perm solution, etc., in addition to rough hands due to excessive shampooing.

As a skin protective agent that improves the drawbacks of conventional hunt creams, it has been proposed that an acrylic polymer consisting of ethyl acrylate and methacrylic acid and a cellulose derivative are dissolved in aqueous alcohol. 2-9006). However, since the acrylic polymer that is the main component of this skin protectant is alkali-soluble, it is difficult to clean the skin with soap, which is commonly used as a base for skin cleansers, or when the liquid is usually alkaline. It has the disadvantage that its protective function is not sufficient when it comes into contact with perm solution.

Therefore, the present invention is capable of forming a film that spreads easily and has a good feeling of use with less stickiness, that is not easily washed away even by washing the skin with water or soap, and that protects the skin for a long period of time. The present invention aims to provide a protective agent composition.

[Means for Solving the Problems] Under these circumstances, the present inventors conducted intensive research and found that a skin protection solution that satisfies the above requirements can be achieved by using a combination of a specific oily substance and perfluoropolyether as the oily component. The present invention was completed based on the discovery that a drug composition can be obtained.

That is, the present invention provides a skin protectant composition containing the following components (A) and (B) in a total weight ratio of 1O:1 to 1:2 in an amount of 80% by weight or more in the total oily component. It provides:

(A) Oily substance having a softening point of 35°C or higher and an organic/inorganic value of 4 or higher (B) Oily perfluoropolyether In the present invention, "softening point" refers to the "ring and ball method". (Cosmetic raw material standard general sample method 30. A method in which a steel ball of a certain weight is placed on a sample of a certain thickness, heated, and the temperature is measured when the steel ball hangs down a certain distance) The value of

Furthermore, "organic/inorganic" refers to Fujita's "Domain of Chemistry 1".
Volume 1, No. 10, pages 719-725 (1957)
This refers to the value in the organic concept shown in ``. this is,
The properties of organic compounds are understood to be determined by two factors: the ``organic nature'' of hydrocarbons, which is based on the accumulation of covalent bonds, and the ``inorganic nature'', which is the effect of electrostatic properties present in substituents.

The calculation method is that for organic properties, the number is 20 multiplied by the number of carbon atoms, and for inorganic properties, it is a number determined for each substituent (for example, 10 times the hydroxyl group).
Generally speaking, 0 and 150 carboxyl groups are added.

Examples of oily substances used as component (A) in the present invention include vaseline, solid paraffin, and ceresin (because the inorganic value is O, the organic/inorganic value is infinite. Below, the numbers in parentheses indicate organic ), stearyl stearate (12,0), cetyl palmitate (10,
7), myristyl balmitate (10,0), cetyl myristate (10,0), myristyl myristate (9
3), glyceryl tripalmitate (57), glyceryl trimyristate (5,0), cholesteryl isostearate (8,8), and the like. These alone are
Alternatively, two or more types can be used in combination. In addition, oily substances with a softening point of 35°C or higher or an organic/inorganic value of less than 4 and which do not fall under component (A) include cetyl alcohol (3,2), stearyl alcohol (3,2), and stearyl alcohol (3,2). , 6), palmitic acid (2,1), stearic acid (24), glyceryl civalmitate (32), and the like.

The oily perfluoropolyether as the component (B) used in the present invention is characterized by the poor spreadability of the oily substance as the component (A);
It has the effect of improving the sticky feeling, poor skin feel after washing, etc., and improving the water resistance of the composition, for example, the following general formula % [where R1, R3, R4 and R5 may be the same or different, and each represents a fluorine atom, a perfluoroalkyl group, or a perfluoroalkyloxy group, R2 represents a fluorine atom or a perfluoroalkyl group, and p, q, and r represent a molecular weight of 500 to 100,000. Indicates a number greater than or equal to 0.

However, p-q=r=o is never satisfied. ] Note that the perfluoro groups shown in parentheses here do not need to be arranged in this order, and random polymerization or block polymerization may be used. As the perfluoropolyether that is susceptible to sagging, a liquid one having a viscosity of 5 to 5,000 cSt is particularly preferable.For example, it has the following general formula (I[) F3 CF30? -fcF, oteCF3(II
) (In the formula, m and n represent numbers with a molecular weight of 500 to 10,000, and 07m is 0.2 to 2.)
), HC-25 (3,200) and HC-R (6,600) (manufactured by Montefros), and the following general formula (m) F-+CFzCF2CF20h-CFzCF
Demnum 5-20 (weight average molecular weight 25,000) Demnum 5-65 (weight average molecular weight 4,500) represented by s (m) (in the formula, p represents a number from 4 to 500),
Same S-100 (5.600) and S-200 (8
, 400) (manufactured by Daikin Industries, Ltd.) and the like can be used.

Component (A) and component (B) are blended in the skin protectant composition of the present invention at a weight ratio in the range of 10:1 to 1:2, but the preferred blending ratio is 4:1 to 2:3. It is. (A
) If the amount of component (B) exceeds 10 times the amount of component (B), the feeling of use such as spread and stickiness will worsen, and if the amount of component (B) exceeds twice the amount of component (A) In this case, the storage stability of the skin protectant composition of the present invention decreases. Also,
The skin protectant composition of the present invention contains component (A) and component (B).
It is preferable that the total amount of both components is 80% by weight or more, particularly 90% by weight or more of the total oily component. Note that amphiphilic substances blended for the purpose of emulsification, such as glyceryl monostearate, are not included in the oily substances.

In addition to the above-mentioned essential components, the skin protectant composition of the present invention may contain optional components such as aqueous components, emulsifiers, preservatives, antioxidants, fragrances, powders, etc., depending on the purpose and within the range that does not impair the effects of the present invention. By appropriately blending the components, it can be made into various forms such as solid, paste, water-in-oil, or oil-in-water emulsions.

[Examples] Hereinafter, the present invention will be explained in more detail by way of Examples, but the present invention is not limited thereto.

Example 1 Among the compositions shown in Table 1, all components except purified water were 70 to 80%
After stirring and dissolving at °C, purified water at 70 to 80 °C was added under stirring, and the mixture was cooled while stirring to obtain each hand cream.

A practical test and a skin protection effect test were conducted on each of the obtained hand creams based on the following test methods.

(1) Practical test (panel test) Each hand cream was actually used on the hands by 10 expert panelists, and a practical evaluation was conducted. The evaluation items were 3 items: ease of application, lack of stickiness, and moist feeling on the skin after washing with soap. The evaluation results are shown in Table 2 according to the following four-level criteria.

◎: The number of people who answered good was 10 out of 10 or more.
0 out of 5 people ×: Less than 10 out of 10 people who answered good The cylinder was placed in close contact with the cylinder, filled with a certain amount of 1% sodium dodecyl sulfate (abbreviated as SDS) aqueous solution, and shaken at a rate of 180 times per minute for 5 minutes.

After removing the SDS aqueous solution, the test site was washed three times with purified water and dried for 10 minutes. Subsequently, the test site was tape-stripped three times to collect the stratum corneum. The amount of SDS in the obtained stratum corneum was determined by the nibton method. Table 2 shows the average value (N·5) of the measured values. Note that a small value means that the effect of suppressing the penetration of SDS into the stratum corneum and protecting the skin is high.

*: FOMBLIN HC-04 manufactured by Montefloss (blank below) Table 2 As is clear from Table 2, the skin protectant composition of the present invention has a better feeling of use and an excellent skin protection effect than the comparative products. ing.

Example 2 Skin protection ointment (% by weight) ■Vaseline 700■
Cholesteryl isostearate 10.0 ■ Glyceryl trimyristate 30 ■ Ceresin
20 ■ Perfluoropolyether (FOMBLfN IC-25 manufactured by Montefloss)
15.0 Ingredients (1) to (2) were heated and dissolved at 70 to 80°C, and then component (2) was added with stirring, and the mixture was cooled while stirring to obtain a skin protection ointment.

The ointment thus obtained spreads easily, has little sticky feeling, and maintained smoothness on the skin even after washing with soap three times.

Example 3 Lip protection stick (% by weight) ■Cetyl palmitate 5゜■Myristyl myristate 25.0■Solid paraffin 10.0■Vaseline
35.0 ■ Perfluoropolyether (FOMBLIN HC-25 manufactured by Monte70s)
23.0 ■Titanium oxide
2.0 Ingredients ■ to ■ were heated and melted at 70 to 80 ''C, mixed uniformly, and component ■ was added and kneaded with a roll mill to uniformly disperse. Subsequently, after melting again, it was poured into a container,
A lip protection stick was obtained by molding.

The obtained stick was highly water-resistant and oil-resistant, and was excellent in preventing dryness of the lips for a long period of time.

Example 4 Oil-in-water body lotion (% by weight) ■ Glycerin tribalmitate 50 ■ Solid paraffin 40 ■ Perfluoropolyether (FOMBLIN IC-R manufactured by Monteflos)
2.0 ■ Polyoxyethylene monooleate (10E, 0.) 2
．． 0■ Methylparaben 03■
Glycerin 30■ Carboxyvinyl polymer (Carbopol 941 manufactured by Gutdrich) 0,2■
Potassium hydroxide 0.1■ Purified water 834 Ingredients (1) and (2) were added to component (1), mixed with heat, and maintained at 70-80°C. On the other hand, after mixing and heating components (1) to (2) to 70 to 80°C, component (2) was gradually added with strong stirring to uniformly disperse the mixture. This oil phase was added to the aqueous phase for preliminary emulsification, then component (2) was added to neutralize it, and the mixture was uniformly emulsified using a homomixer. The obtained emulsion was heated in a heat exchanger for 30 minutes.
It was cooled to °C and filled into containers to obtain a body lotion.

[Effects of the Invention] As described above, the skin protectant composition of the present invention can
It is highly effective in protecting the skin from skin cleansing processes, etc., and is also excellent in terms of feel, such as good spreadability and low stickiness.

that's all

Claims (1)

[Claims] (1) Add 1 part of the following ingredients (A) and (B) into the total oily ingredients.
1. A skin protectant composition comprising a total of 80% by weight or more in a weight ratio of 0:1 to 1:2. (A) Oily substance with a softening point of 35°C or higher and an organic/inorganic value of 4 or higher (B) Oily perfluoropolyether