JPH04338337A - Antidermatomycotic agent - Google Patents
Antidermatomycotic agentInfo
- Publication number
- JPH04338337A JPH04338337A JP3141158A JP14115891A JPH04338337A JP H04338337 A JPH04338337 A JP H04338337A JP 3141158 A JP3141158 A JP 3141158A JP 14115891 A JP14115891 A JP 14115891A JP H04338337 A JPH04338337 A JP H04338337A
- Authority
- JP
- Japan
- Prior art keywords
- agent
- antidermatomycotic
- alcohol
- flowers
- sesame
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 13
- 241000207961 Sesamum Species 0.000 claims abstract description 8
- 235000003434 Sesamum indicum Nutrition 0.000 claims abstract description 8
- 229940098465 tincture Drugs 0.000 claims abstract description 4
- 239000003795 chemical substances by application Substances 0.000 claims description 8
- 239000000645 desinfectant Substances 0.000 claims description 5
- 230000002538 fungal effect Effects 0.000 claims description 5
- 238000002791 soaking Methods 0.000 claims description 3
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 abstract description 10
- 235000019441 ethanol Nutrition 0.000 abstract description 8
- 208000002474 Tinea Diseases 0.000 abstract description 4
- BWMISRWJRUSYEX-SZKNIZGXSA-N terbinafine hydrochloride Chemical compound Cl.C1=CC=C2C(CN(C\C=C\C#CC(C)(C)C)C)=CC=CC2=C1 BWMISRWJRUSYEX-SZKNIZGXSA-N 0.000 abstract description 2
- 201000004647 tinea pedis Diseases 0.000 abstract description 2
- 208000007163 Dermatomycoses Diseases 0.000 abstract 1
- 206010039509 Scab Diseases 0.000 abstract 1
- 241000130764 Tinea Species 0.000 abstract 1
- 206010067409 Trichophytosis Diseases 0.000 abstract 1
- 201000003929 dermatomycosis Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 description 5
- 229940079593 drug Drugs 0.000 description 5
- 241000287828 Gallus gallus Species 0.000 description 2
- 208000031888 Mycoses Diseases 0.000 description 2
- 241000893966 Trichophyton verrucosum Species 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 229940121375 antifungal agent Drugs 0.000 description 2
- 239000003429 antifungal agent Substances 0.000 description 2
- 235000007215 black sesame Nutrition 0.000 description 2
- IPCSVZSSVZVIGE-UHFFFAOYSA-N hexadecanoic acid Chemical compound CCCCCCCCCCCCCCCC(O)=O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 description 2
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 2
- 239000008159 sesame oil Substances 0.000 description 2
- 235000011803 sesame oil Nutrition 0.000 description 2
- 230000000699 topical effect Effects 0.000 description 2
- OYHQOLUKZRVURQ-NTGFUMLPSA-N (9Z,12Z)-9,10,12,13-tetratritiooctadeca-9,12-dienoic acid Chemical compound C(CCCCCCC\C(=C(/C\C(=C(/CCCCC)\[3H])\[3H])\[3H])\[3H])(=O)O OYHQOLUKZRVURQ-NTGFUMLPSA-N 0.000 description 1
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 description 1
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 description 1
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 description 1
- 206010001557 Albinism Diseases 0.000 description 1
- 240000005979 Hordeum vulgare Species 0.000 description 1
- 235000007340 Hordeum vulgare Nutrition 0.000 description 1
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 description 1
- 239000005642 Oleic acid Substances 0.000 description 1
- 235000021314 Palmitic acid Nutrition 0.000 description 1
- 235000002245 Penicillium camembertii Nutrition 0.000 description 1
- 239000004264 Petrolatum Substances 0.000 description 1
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 description 1
- 239000004327 boric acid Substances 0.000 description 1
- 230000000249 desinfective effect Effects 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 description 1
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 1
- WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
- 235000021313 oleic acid Nutrition 0.000 description 1
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 1
- 229940066842 petrolatum Drugs 0.000 description 1
- 235000019271 petrolatum Nutrition 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 229960004889 salicylic acid Drugs 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
Landscapes
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Description
【０００１】0001
【産業上の利用分野】この発明は、皮膚真菌症に有効な
外用の抗皮膚真菌剤、特にみずむし、たむし、しらくも
、はたけなどの白せん菌に有効な外用の抗白せん菌剤の
改良に関するものである。[Industrial Application Field] This invention provides a topical anti-skin anti-fungal agent effective for skin mycoses, especially a topical anti-dermal anti-fungal agent effective against athlete's foot, ringworm, ringworm, white mold, etc. It is about improvement.
【０００２】0002
【従来の技術】この種の薬剤としては、ヨードチンキ、
サルチル酸ワセリン、ホウ酸水、むくげの木きん（皮、
花、果実）を生薬として用いたチンキ剤など数多くのも
のが知られている。[Prior art] This type of drug includes iodine tincture,
Salicylic acid petrolatum, boric acid solution, barley wood (skin,
Many tinctures and other medicines are known that use flowers, fruits) as herbal medicines.
【０００３】0003
【発明が解決しようとする課題】しかとこれらの公知の
薬剤に、今一つ薬効が芳しくないことから、より薬効の
あるものが求められている。[Problems to be Solved by the Invention] However, since these known drugs have poor medicinal efficacy, there is a need for a drug with even higher medicinal efficacy.
【０００４】この発明は上記の点に鑑み、一段と薬効が
優れた抗皮膚真菌剤、特に抗白せん菌剤を提供すること
を目的としている。[0004] In view of the above-mentioned points, an object of the present invention is to provide an anti-skin fungal agent, particularly an anti-white mold agent, which has even better medicinal efficacy.
【０００５】[0005]
【課題を解決するための手段】この発明によれば上記の
目的は、ごま（胡麻）の花を消毒用アルコールに浸漬し
て製造したチンキ剤からなる抗皮膚真菌剤、特に抗白せ
ん菌剤によって達成する。[Means for Solving the Problems] According to the present invention, the above object is to provide an anti-skin fungal agent, especially an anti-white mold agent, comprising a tincture prepared by soaking sesame flowers in disinfectant alcohol. achieved by.
【０００６】ここでごまの花としては、一般に食用やご
ま油採取用として栽培されている白ごまうや黒ごまの花
等を用いることができる。[0006] As the sesame flowers, white sesame flowers, black sesame flowers, etc., which are generally cultivated for food or for extracting sesame oil, can be used.
【０００７】また消毒用アルコールとしては、エチルア
ルコールやイソプロパノール（イソプロピルアルコール
）などを用いることができる。[0007] As the disinfecting alcohol, ethyl alcohol, isopropanol (isopropyl alcohol), etc. can be used.
【０００８】なおごまの花のエチルアルコールにおける
浸漬は、一般には容器における密封状態で１ケ月以上行
なう。[0008] Sesame flowers are generally soaked in ethyl alcohol for one month or more in a sealed container.
【０００９】[0009]
【作用】この発明の抗皮膚真菌剤では、消毒用アルコー
ル中に浸出（溶出）したごまの花の含有成分（未確認で
あるが、ごま油の成分からオレイン酸、リノール酸、パ
ルミチン酸などが予測される）と、消毒用アルコールと
が相乗的な殺菌ないし抗菌作用を奏するものと推定され
る。[Action] The anti-skin fungal agent of this invention contains components of sesame flowers leached (eluted) into disinfectant alcohol (although unconfirmed, oleic acid, linoleic acid, palmitic acid, etc. are predicted from the components of sesame oil). It is presumed that disinfectant alcohol and disinfectant alcohol have a synergistic bactericidal or antibacterial effect.
【００１０】0010
【実験例１】白ごまの花を５００ｇをエチルアルコール
（７０パーセント）１ｌに１ケ月以上漬けて製造したチ
キン剤を、数人の軽症のみずむし部（足部）に１日三回
ずつ塗布し続けたところ、約１０〜１５日で完治した。[Experiment Example 1] A chicken agent prepared by soaking 500 g of white sesame flowers in 1 liter of ethyl alcohol (70%) for over a month was applied three times a day to the mildly affected athlete's feet (feet) of several people. After continued treatment, it completely healed in about 10 to 15 days.
【００１１】また数人の重症のみずむし部（足部）に同
じ頻度で塗布を続けたところ、約６ケ月〜１年でほぼ治
癒した。[0011] When several people continued to apply the product at the same frequency to the severely affected parts of their feet, they were almost cured in about 6 months to 1 year.
【００１２】0012
【実験例２】黒ごまの花を用いた以外は実験例１と同様
の条件で製造したチンキ剤について、同様の試験を行な
ったところ、ほぼ同等の結果が得られた。[Experimental Example 2] A similar test was conducted on a tincture prepared under the same conditions as in Experimental Example 1 except that black sesame flowers were used, and almost the same results were obtained.
【００１３】[0013]
【実験例３】イソプロパノール（５０パーセント）を用
いた以外は実験例１と同じ条件で製造したチキン剤を用
いて、同様の試験を行なったところ、ほぼ同じ結果が得
られた。[Experimental Example 3] A similar test was conducted using a chicken preparation prepared under the same conditions as in Experimental Example 1, except that isopropanol (50%) was used, and almost the same results were obtained.
【００１４】[0014]
【発明の効果】以上のようにこの発明の抗皮膚真菌剤は
、皮膚真菌症、特に白せん症を公知の薬剤よりも短期間
でほぼ完全に治療することができるという優れた薬効を
有している。[Effects of the Invention] As described above, the antidermal fungal agent of the present invention has excellent medicinal efficacy in that it can almost completely treat skin fungal diseases, especially albinism, in a shorter period of time than known drugs. ing.
Claims (1)
造したチンキ剤からなる抗皮膚真菌剤。Claim 1: An anti-skin fungal agent comprising a tincture prepared by soaking sesame flowers in disinfectant alcohol.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3141158A JPH07103040B2 (en) | 1991-05-15 | 1991-05-15 | Worm remedy |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3141158A JPH07103040B2 (en) | 1991-05-15 | 1991-05-15 | Worm remedy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH04338337A true JPH04338337A (en) | 1992-11-25 |
| JPH07103040B2 JPH07103040B2 (en) | 1995-11-08 |
Family
ID=15285483
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP3141158A Expired - Lifetime JPH07103040B2 (en) | 1991-05-15 | 1991-05-15 | Worm remedy |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH07103040B2 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008247783A (en) * | 2007-03-29 | 2008-10-16 | Naris Cosmetics Co Ltd | External preparation composition |
-
1991
- 1991-05-15 JP JP3141158A patent/JPH07103040B2/en not_active Expired - Lifetime
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008247783A (en) * | 2007-03-29 | 2008-10-16 | Naris Cosmetics Co Ltd | External preparation composition |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH07103040B2 (en) | 1995-11-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Burlando et al. | Honey in dermatology and skin care: a review | |
| JPS6087204A (en) | Highly fungicidal composition comprising biguanide andpyrimidine | |
| EP1095660A3 (en) | Therapeutic combination containing terpinen-4-ol and medicinal plants | |
| MY131702A (en) | Combinations of a fungicide containing an azole group with an insecticide containing a pyrazole,pyrrole 0r phenylimidazole group. | |
| CN103585058A (en) | Lavender compound essential oil | |
| JPH04338337A (en) | Antidermatomycotic agent | |
| CN103585056A (en) | Bergamot composite essential oil | |
| ES2156446T3 (en) | SEMISOLID PHARMACEUTICAL FORMULATION CONTAINING TROMETHANOL DEXKETOPROPHENE. | |
| CN103585057A (en) | Mint compound essential oil | |
| CN105920075A (en) | Externally-used drug of ozone antibacterial agent | |
| El Sheikha | Rumex nervosus: an overview | |
| US20130052289A1 (en) | Medicine containing extracts of Ficus microcarpa for healing wounds of a diabetic patient | |
| Taufan et al. | Utilization of Antiseptic Soap as an Effort to Maintain Community Economic Stability in Padang Lampe Village, Pangkep-South Sulawesi Province | |
| CN101204470B (en) | Application of grape fermented product on skin sterilization and health protection products filed | |
| GB2584599A (en) | Alcohol gels for the treatment of athletes foot | |
| CN1977849A (en) | Kibe ointment with bactericidal-bacteriostasis function | |
| CN103948607A (en) | Germicidal and bacteriostatic chilblain cream | |
| KR20220083020A (en) | Pharmaceutical composite formulation for treating vascular dementia with alzheimer's disease | |
| Sagar et al. | Cytotoxic and Antimicrobial Effects of Herbal Formulation (Ficus benghalenis, Azadirachta indica and Menthapiperita) Based Mouthwash | |
| FR2224169A1 (en) | Antimicrobial fatty acid/amino acid compounds - for use against microorganisms (bacteria, fungi, viruses) in humans, animals and plants | |
| KR20230090187A (en) | Pharmaceutical composite formulation for treating vascular dementia with alzheimer's disease | |
| Lakkakula et al. | Role of Panchashirisha Agada in Dermatological Toxicity wsr to Visha-A Review | |
| Chowdappa et al. | Proceedings of the Workshop on Arecanut and Human Health | |
| KR101913564B1 (en) | Ointment composition for treatment of tinea pedis | |
| DE68916443T2 (en) | MEDICINES FOR TREATING CRYPTOSPORIDIOSIS. |