JPH04189766A - Impact resisting ptp package - Google Patents

Abstract

PURPOSE:To prevent almost completely the contents of PTP package from suffering physical impairments by providing a heat-sealable resin layer having a specific height and an irregular surface on one side of an aluminum foil. CONSTITUTION:In the manufacture of a lid, a heat-sealable resin layer having an irregular surface is formed on one side of the aluminum foil being a base material and the raised part of such surface is made at least 90mum high to impart a cushioning action against impact.

Description

DETAILED DESCRIPTION OF THE INVENTION (Industrial Field of Application) The present invention relates to packaging, particularly PTP packaging. More specifically, it is a packaging type mainly used for packaging solid medicines and foods, and is a container with a recess (pocket) for storing the contents in a plastic sheet and a container for sealing the opening. It consists of a lid material based on aluminum foil or glassine paper, etc., and by pressing the bottom of the container, the lid material at the opening of the container ruptures and the contents can be taken out. P T P (Press Through Pac
k) It concerns a form of packaging called packaging.

(Prior art) PTP packaging, which is widely used as individual containers for food and pharmaceutical packaging, is a plastic sheet made of vinyl chloride resin, polypropylene, etc. that becomes the container part for storing the contents, and is made by air-forming. A plastic sheet with pockets (concavities) formed by a vacuum forming method, etc., and a sheet made of aluminum foil or glassine paper, etc. as a base material, which becomes the indigo part to seal the opening of the pocket. It consists of parts.

Plastic sheets used for PTP packaging containers include vinyl chloride resin, polyester resin, polyamide resin,
Thermoplastic resin sheets such as polyaclonitrile resin and polypropylene resin can be used, but vinyl chloride resin has good moldability, relatively good moisture permeability and air permeability, and is low grade. and polypropylene resins are commonly used.

Lid materials are usually made by printing letters or designs on a base material such as aluminum foil or glassine paper, with or without an undercoat on one or both sides as required, and on one side, the flange of a plastic container is printed. Applying a thermoplastic resin composition to heat-seal the lid by heat-sealing the lid, or heat-sealing a thermoplastic resin film that is easy to tear, or bonding or adhering. It is manufactured by forming a heat-sealable resin layer by adhering it through an agent.

The resin component forming the heat-sealable resin layer is mainly a thermoplastic resin, but for example, when aluminum foil is used as the lid material and a vinyl chloride resin sheet is used as the container material, vinyl chloride-vinyl acetate- The main component is a maleic acid terpolymer, etc., and is appropriately selected depending on the materials of the container base material and the lid material and other required performances.

Furthermore, a clear heat-resistant overcoat agent or plastic film, either colorless or colored, is usually applied to the opposite side to protect the printed film.

PTP packaging is made by storing the contents in the recesses of a pocket of a plastic sheet such as a vinyl chloride resin sheet or a polypropylene sheet that forms the pocket that becomes the container, and then applying the above-mentioned lid material to the opening side of the pocket with a heat-sealing resin layer. This is accomplished by stacking the plastic containers so that they are in contact with each other, heating them from the opposite side of the heat-sealable resin layer of the lid material with a heat-sealing bar or heat-sealing roll, and applying pressure at the same time to fuse them to the flange of the plastic container and heat-seal them. be done.

The heating and pressing conditions, that is, the heat sealing conditions, vary depending on the material of the container to be adhered, but the heat sealing temperature is 100°C to 200°C, usually 120°C to 180°C, and the heat sealing pressure is 1 to 6 kg. / cm2, usually 1 to 3 kg
/ cm It is often set to m2.

(Problems to be Solved by the Invention) Items stored in PTP packaging include tablets, pellets, and capsules for pharmaceuticals, foods, and confectionery, and they are protected from physical, chemical, and biological damage. used for protection purposes.

Conventionally, strip packaging was often used for individual packaging of tablets, but it is gradually being replaced by PTP packaging, which significantly reduces damage such as cracks and chips caused by external physical impact and pressure, and The visibility of the contents has made them easier to handle.

However, even in PTP packaging, relatively large tablets such as sublingual tablets often suffer physical damage during transportation and handling at a considerable rate.

(Means for solving the problem) The present inventors have developed a PTP package for packaging large tablets as described above.
After observing the state of damage to the contents of the package, we found that the most likely case of damage is when the lid material collides with a hard surface. After repeated studies, we have arrived at the present invention.

In other words, tablets and the like stored in ordinary commercially available PTP packaging bodies that use lidding materials whose heat-sealing resin layer has a thickness of at most several micrometers may suffer from physical stability during transportation and handling of such packaging bodies. According to a test method used as an alternative test for strength, in which the lid material is dropped onto a smooth concrete surface from a height of 1 m, the breakage rate of tablets is more than 50%. The heat-sealing resin layer provided on one side of the aluminum foil that is the base material has an uneven shape, and the height of the convex portion is 9.
They completed the present invention by discovering that tablets and the like stored in a PTP package using a lid material that has a shock-reducing effect by having a thickness of 0 μ or more are not damaged at all.

(Functions and Effects) As described above, the PTP packaging body of the present invention has a heat-sealable resin layer provided on one side of aluminum foil in an uneven shape, and the packaging material has a convex portion height of at least 90 μm as a lid material. This is an impact-resistant PTP packaging body characterized by the following.

The heat-sealing resin layer provided on the lid of the PTP package of the present invention is provided in an uneven shape, but even if the protrusions are discontinuously arranged, the convex portions, that is, high portions, and the concave portions, that is, low portions, are continuous. The parts may be arranged alternately without being disconnected. Further, the shape of the convex portion is not limited to a cylinder, a cone, a prism, a pyramid, etc., and may be in the shape of a strip or a rib. If the concave portions are not continuously formed to have an appropriate thickness or less, the ease of opening the PTP package, that is, the characteristic of the PTP package that the cover material is not easily burstable will be lost.

In order to almost completely prevent physical damage to the contents of the PTP package, the height of the convex portion of the heat sealable resin layer needs to be 90μ or more, but there is no particular upper limit and the height of the heat sealable resin composition Since there are inevitably restrictions due to issues such as the physical properties of the product, the ability of the coating machine, the handling of the coated substrate, and economic efficiency,
μ.

The resin composition for forming the heat-sealable resin layer of the lid material used in the PTP package of the present invention is appropriately selected depending on the combination of the material of the container and the material of the lid material, as described above. However, its form is also arbitrary. However, solution-type resin compositions are difficult to use because they are limited by solid content concentration and have high fluidity, and in the case of easily ruptured adhesive films, it is difficult to form irregularities.

Therefore, heat melt coating using a gravure plate of a solid resin composition, screen powder coating, etc. are appropriate.

Alternatively, a solution-type heat-sealable resin composition may be applied by a conventional method, or an adhesive film may be applied to the base material of the lid material by thermocompression bonding or dry lamination, and then a solid resin composition may be heated on top of the adhesive film. It is also possible to combine various coating methods, such as providing unevenness by melt coating or screen powder coating.

Hereinafter, the present invention will be explained in more detail with reference to Examples.

[Example 1] <Manufacture of heat-sealable resin composition (A>) A stainless steel-made heating jacket equipped with a partial condenser, a total condenser, an inert gas introduction line, a bottom outlet, and an anchor-shaped stirring blade. Capacity 120
Put the raw materials into a Little Mixer according to the following formula,
Introduction of nitrogen gas was started, and heat transfer oil was passed through the jacket to raise the temperature as quickly as possible.

Paraffin wax (manufactured by Hiki Seirogami, 39kg, melting point 1)
45Cα) Ethylene-vinyl acetate copolymer (manufactured by San 44kg Petrochemical Industry ■, product name: Evaflex EV150, softening point: 120cα, melt index: 30, vinyl acetate content: 33%) Hydrogenated terpene resin (cheap crude oil Made by Kogyo ■, 17kgProduct name: Clearon M-105, softening point 105Cα)Total 100kg After about 30 minutes,
When the internal temperature reached 180°C and it was confirmed that the contents were starting to melt, stirring was started. During stirring and mixing, the indoor bath is heated to 18
It was maintained at 0°C. -After a period of time, after confirming that the contents are in a uniform transparent liquid state, the solid heat-sealable resin composition (A) is poured out into a duralumin pan from the bottom outlet.
I got it.

<Preparation of coated aluminum foil for lid material> Apply a heat-resistant varnish of the following composition to the glossy surface of a hard aluminum foil with a thickness of 20μ so that the dry film thickness is 3μ, and heat-dry at 180°C for 10 seconds. A coated aluminum foil for lidding material was prepared by processing.

Phenoxy resin (manufactured by Dainippon Ink Chemical Co., Ltd. 3 (parts by weight) Gakkogyo ■, Evicron EXA-415, 55% solution) Butyl etherified melamine resin 14 (manufactured by Dainippon Ink Chemical Co., Ltd. ■, Super Beckamine J-820-60, 60 % solution) Methyl ethyl ketone 20 toluene
24 isopropyl alcohol
4 cyclohexane 4 total
100 <Preparation of lid material> Using a coating machine equipped with a gravure plate with a depth of 180 μm and a 34-mesh coating solution prepared by melting the heat-sealable resin composition (A) at 170° C., apply the coating solution as described above. It was applied to the matte surface of coated aluminum foil.

The height of the convex portion of the heat sealable resin layer of the obtained lid material was 129μ
Met.

<Creation of PTP packaging> A hard vinyl chloride resin sheet (VSS1202 manufactured by Sumitomo Bakelite ■) with a thickness of 250μ is used as a base material, and a 24 wxa
X 24 squares with a diameter of 19m5 and a depth of 5m in the center
A PTP container was formed by forming a thin cylindrical pocket.

Tablets formed by using calcium carbonate and carboxymethylcellulose as excipients to give a hardness value of 15 kg as measured by a Honya type hardness tester (Utility Model Registration No. 174886) are stored in this container, and the lid material is heated. The sealing resin layer was placed so as to face the opening of the container, and a heat sealing temperature of 130°C and a heat sealing pressure of 5.5 kg/cr [r'
and PTP by flat sealing under the conditions of pressurization time of 1 second.
A package sample was created.

<Impact resistance test of PTP packaging> The PTP packaging described above was dropped onto a smooth concrete surface from a height of 1 m with the lid facing down to check for cracks. No damage such as cracks or chips occurred.

[Example 2] In Example 1, when creating the lid material, the molten coating liquid of the heat-sealable resin composition (A) was applied to a depth of 1 with 40 meshes.
A PTP packaging sample was prepared in the same manner except that it was carried out using a 20μ gravure plate and the height of the convex part of the heat sealable resin layer of the lid material was 98μ, and an impact test was conducted. There was no physical damage such as cracks or chips to the samples.

[Comparative Example 1] In Example 1, when creating the lid material, the molten coating liquid of the heat-sealable resin composition (A) was applied using a gravure plate with a depth of 110 μm to improve the heat sealability of the lid material. The height of the convex part of the resin layer is 85
PTP package samples were prepared in the same manner except that μ was used, and an impact test was conducted, but physical damage such as cracks and chips was observed in 6 out of 50 samples. .

[Comparative Example 2] Instead of the heat sealable resin composition (A) of Example 1,
As an example of a composition used to provide a sealing resin layer of a lidding material for PTP, the following composition is blended and stirred and dissolved under heating at 60 to 70°C to form a heat sealable resin. Composition (B) was produced.

Ethylene-vinyl acetate copolymer 37 parts (Taisei Kayaku, trade name: Swalex CH40T 40% toluene solution) Vinyl chloride-vinyl acetate copolymer 85 parts (U.S.
(manufactured by CC Corporation, trade name: Vinyrite VMCH) Toluene 139 parts Methyl ethyl ketone 139 parts Total 400 parts In Example 1, the heat-sealable resin composition (B) was used instead of the heat-sealable resin composition (A). PTP packaging samples were prepared using the same method except that the thickness of the heat-sealable resin layer of the lid material was 3μ, and an impact resistance test was conducted. Physical damage such as cracks and chips was observed in 36 of the pieces.

[Example 3] In creating a lid material, a carboxy-modified ethylene-vinyl acetate copolymer (manufactured by Mitsui Petrochemical Industries, Ltd., trade name Atomer 300) was molded onto the matte surface of a coated aluminum foil to a thickness of 30 μm. The films were laminated together by a dry lamination method, and the heat-sealable resin composition (A) was applied thereon in the same manner as in Comparative Example 1, the height of the convex portion of the coated resin layer was set to 85μ, and heat-sealed. The height of the convex part as a resin layer is 1
15μ, otherwise treated in the same manner as in Example 1, and PT
When a P package sample was created and an impact test was conducted, it was 5.
No abnormalities were observed in any of the 0 samples.

Patent applicant Leader Co., Ltd.

Claims (1)

[Claims] An impact-resistant PTP packaging body, characterized in that a lidding material is a packaging material in which a heat-sealing resin layer is provided on one side of an aluminum foil in an uneven pattern and the height of the convex portion is at least 90 μm.