JPH04114350U - Heat exchanger and blood reservoir - Google Patents

Abstract

(57) [Summary] [Structure] The blood storage tank 1 includes a housing 2 having a blood storage space 5 for storing blood therein, and a heat exchanger 9 for heating or cooling the blood. The heat exchanger 9 connects the lower blood storage space 5
It has a plurality of metal tubes 10 installed in parallel and inclined at a predetermined angle with respect to the horizontal plane H. A reduced diameter portion 101 having a smaller diameter than other parts is formed at the vertically upper end of each tube body 10. As a result, a passage 102 in which air bubbles can float is formed in the gap between adjacent reduced diameter portions 101 .
Both ends of each tube body 10 communicate with a heat medium chamber 16 within the housing 14 and a heat medium chamber 17 within the housing 15, respectively. When the blood storage space 5 is primed, air bubbles mixed in the priming liquid gather obliquely upward along the slope of each tube body 10, float up through the passage 102, and are discharged. [Effect] Excellent bubble removal performance and high heat exchange efficiency.

Description

[Detailed explanation of the idea]

0001

[Industrial application field]

This invention is a heat exchanger that is installed in an extracorporeal blood circulation circuit and heats or cools blood. and a blood storage tank provided with the same.

0002

[Conventional technology]

For example, in cardiac surgery, a blood pump is activated to remove blood from the patient's veins. This blood is then returned to the patient's artery after gas exchange is performed using an oxygenator. Extracorporeal blood circulation is performed through the artificial lung. This oxygenator extracorporeal blood circulation circuit has a It is equipped with a blood storage tank that temporarily stores the collected blood, and a heat exchanger that adjusts the temperature of the blood. be placed.

0003 The blood reservoir has a buffer function that adjusts the amount of blood in the circuit and keeps the amount of blood returned constant. At the same time, it also has the ability to defoam the blood that has been drained.

0004 In addition, heat exchangers can be used, for example, to cool blood to around 20°C during surgery, and to At the end of surgery, it is used to warm the blood to return it to body temperature.

[0005] In such an extracorporeal blood circulation circuit, the circuit is designed to reduce the burden on the patient. The challenge is to minimize the amount of blood priming within the body. Therefore, blood storage tanks with built-in heat exchangers have been developed. This blood reservoir is The housing has a blood storage space in the blood storage space, and a coiled metal tube is installed in the blood storage space. A heat exchange medium (hereinafter referred to as a heat medium) is passed through the metal tube, and the metal tube Blood in the blood storage space is heated by exchanging heat between the heat medium and the blood through the tube wall. heating or cooling.

[0006] In addition, in order to further improve heat exchange efficiency, instead of using coiled metal tubes, we installed parallel tubes. Developed a heat exchanger using multiple metal straight pipes and a blood storage tank with built-in heat exchanger. has been done.

[0007] In such heat exchangers and blood storage tanks, straight pipes are used to increase heat exchange efficiency. In addition to increasing the installation density, the gap distance between the inner wall of the housing and the adjacent straight pipe It is necessary to minimize channeling and prevent channeling. A problem arises.

[0008] In other words, before starting extracorporeal blood circulation, the blood circulation circuit is filled with physiological saline. Priming is done with a priming liquid such as water, but the priming liquid itself contains bubbles. priming, or air bubbles generated at the joints of tubes or parts. These air bubbles may get mixed in with the cleaning fluid, and these air bubbles can be found in the gaps between straight pipes or between straight pipes and hoses. It cannot float through the gap with the inner wall of the heat exchanger and remains inside the heat exchanger.

[0009] If these air bubbles remain, blood may not be returned to the artery when extracorporeal blood circulation is started. There is a risk that the bubbles may get mixed into the blood, which is extremely dangerous for living organisms. In addition, to remove such bubbles, the heat exchanger and blood storage tank are shaken or vibrated. However, the equipment becomes complicated and the results are not sufficiently effective. won.

0010

[Problem that the idea aims to solve]

The purpose of the present invention is to provide a heat exchanger and a blood storage tank in which no air bubbles remain. It is in.

[0011]

[Means to solve the problem]

Such objects are achieved by the present invention described in (1) to (3) below. (1) A housing with a blood storage space formed therein, and blood communicating with the blood storage space. A fluid inlet, a blood outlet, and a tube constructed within the blood storage space and mainly composed of a straight pipe section. a plurality of tube bodies; a heat medium supply section that supplies a heat medium into the tube bodies; A heat exchanger comprising a heat medium discharge part that discharges the heat medium that has passed through the heat exchanger, The straight pipe portion of each pipe body is installed inclined with respect to the horizontal plane, and A heat exchanger characterized in that the outer diameter of the vertically upper end of the straight pipe portion is reduced. .

0012 (2) A housing with a blood storage space formed therein, and blood communicating with the blood storage space. It is constructed in the blood storage space with an inflow port and a blood outflow port, and is mainly composed of a straight pipe section. a plurality of tube bodies; a heat medium supply section that supplies a heat medium into the tube bodies; A heat exchanger comprising a heat medium discharge part for discharging the heat medium that has passed through the heat exchanger, The straight pipe portion of each pipe body is installed inclined with respect to the horizontal plane, and A heat exchanger characterized in that the vertically upper end of the straight pipe part has a flat shape. vessel.

[0013] (3) Each of the pipe bodies is a straight pipe arranged in parallel, and the openings at both ends of each straight pipe are closed. (1) or (2) above, in which both ends of each straight pipe are supported by partition walls without Heat exchanger described in.

[0014] (4) Features a heat exchanger according to any one of (1) to (3) above. blood reservoir.

[0015]

[Effect]

According to the present invention having such a configuration, the straight pipe portion of each pipe constructed within the blood storage space is , because it is inclined with respect to the horizontal plane, the space below the pipe body, the gap between the pipe bodies, and Microscopic air bubbles existing in the gap between the pipe body and the inner wall of the housing are The liquid then moves diagonally upward and gathers near the vertically upper part of each straight pipe section.

[0016] The vertically upper end of this straight pipe section has a reduced or uneven outer diameter. It has a flat shape, and there is a path between these reduced diameter parts or flat parts where air bubbles can float. As a result, the collected air bubbles float through this passage and are discharged above the heat exchanger. be done.

[0017] Note that this passage is formed in a part of the straight pipe section in the longitudinal direction, so it is difficult to walk inside the passage. The amount of blood flowing is small, so there is almost no decrease in heat exchange efficiency due to channeling. It's not easy.

[0018]

[Structure of the idea]

Hereinafter, the heat exchanger and blood storage tank of the present invention will be explained based on the preferred embodiments shown in the attached drawings. Explain in detail.

[0019] FIG. 1 is a perspective view showing an example of the configuration of the blood storage tank of the present invention, and FIG. 2 is taken along line A-A in FIG. 3 is a cross-sectional view taken along the line B-B in FIG. 2, and FIG. 4 is a cross-sectional view taken along the line C-C in FIG. FIG. As shown in these figures, the blood reservoir 1 of the present invention has a housing main body. It has a housing 2 composed of a body 3 and a lid 4. Inside this housing 2 A blood storage space 5 for storing blood is formed.

[0020] The housing body 3 has a box shape with a protrusion 31 on the upper right side in FIG. .

[0021] The lid body 4 is placed so as to cover the upper opening of the housing body 3, and the lid body 4 is placed so as to cover the upper opening of the housing body 3, and the lid body 4 is placed so as to cover the upper opening of the housing body 3. Instead of sealing the space 5, for example, through the gap between the housing body 3 and the lid body 4. This allows ventilation between the blood storage space 5 and the outside. As a result, the blood storage space 5 The amount of blood stored in the body can be increased or decreased. Note that the housing 2 is connected to the blood storage space 5 and the outside. A vent hole (not shown) may be provided to allow the air to pass through.

[0022] A tubular blood inlet 6 communicating with the blood storage space 5 is fixed to the lid 4 . child For example, the blood inlet 6 is connected to a tube of a blood removal line in an extracorporeal blood circulation circuit. Connected.

[0023] In addition, a tubular blood outflow port communicating with the blood storage space 5 is provided at the bottom of the housing body 3. 7 is formed. This blood outflow port 7 is used, for example, in an extracorporeal blood circulation circuit. Connected to a tube to an artificial lung, etc.

[0024] The volume of the blood storage space 5 is not particularly limited, but is approximately 3000 to 5000 ml for adults. For children, the volume is preferably about 1,000 to 2,000 ml.

[0025] In addition, the space in the part where the pipe bodies 10 described later are arranged (the gap between the pipe bodies 10 and and the gap between the pipe body 10 and the inner wall of the housing) and the space 51 below it. The actual volume of the blood storage space is about 300 ml or less, especially about 100 to 200 ml (adults) It is preferable that the The reason why such a small volume can be achieved is as described below. This is because the heat exchanger 9 is small and has high performance. The low limit blood storage volume can be lowered than before, reducing the amount of circuit priming. Contribute.

[0026] The constituent materials of the housing body 3 and the lid body 4 include polycarbonate and acrylic. Ril resin, polyethylene terephthalate, polyethylene, polypropylene, poly Styrene, polyvinyl chloride, acrylic-styrene copolymer, acrylic-butadiene Among these, polycarbonate and styrene copolymers are particularly preferred. Polyvinyl chloride is preferred.

[0027] Furthermore, the housing body 3 and lid body 4 allow for visual confirmation of the amount of blood stored. It is preferable that it be transparent so that it can be seen.

[0028] Note that a scale (not shown) is provided on the side surface of the housing body 3 to indicate the amount of blood stored. You can also

[0029] The lower part of the protrusion 31 of the housing body 3 in the figure has a diameter of 1 to 4, for example, with respect to the horizontal plane H. An inclined surface 32 inclined by about 5 degrees is formed.

[0030] The blood storage space 5 in the protrusion 31 also contains blood that has flowed in from the blood inflow port 6. A defoaming member 8 is installed to remove air bubbles contained in the air. This defoaming member 8 A pair of holes are formed on opposite inner walls of the housing body 3, respectively. It is fixed by being inserted between the ribs 33. Moreover, the lower end of the defoaming member 8 is It is in contact with the inclined surface 32.

[0031] As this defoaming member 8, for example, foamed polyurethane, foamed polyethylene, foamed polyethylene, etc. Foamed materials such as foamed polypropylene and foamed polystyrene, woven fabrics, nonwoven fabrics, mesh, and Alternatively, porous materials such as porous ceramics can be mentioned, among which In particular, foamed polyurethane and foamed polyethylene are preferred.

[0032] When using a foam or porous material as the defoaming member 8, the pore diameter is 20 μm to 5 μm. It is preferably about 30 μm to 2 mm, particularly about 30 μm to 2 mm.

[0033] Such a blood storage tank 1 is equipped with a heat exchanger 9 of the present invention. This heat exchanger 9 , the blood stored in the blood storage space 5 is heated or cooled as necessary.

[0034] The heat exchanger 9 includes a plurality of heat exchange tubes 10 installed in the blood storage space 5, and A pair of partition walls 11 that support the tube bodies 10, and a heat source that supplies a heat medium into each tube body 10. A medium supply section 12 and a heat medium discharge section 13 that discharges the heat medium that has passed through each tube body 10. It is equipped with Each component of the heat exchanger 9 will be explained below.

[0035] The pipe body 10 is mainly composed of a straight pipe part, and in the illustrated configuration example, the pipe body 10 is a straight pipe part. be. Note that the pipe body in this invention is not limited to a straight pipe. For example, if the opening angle is 160 to 175 in the middle of a U-shaped pipe that is bent back or a straight pipe, If most of the pipe is straight, such as a V-shaped pipe bent into a mountain shape of about It can be anything.

[0036] Each tube body 10 is installed in parallel and on a horizontal plane (blood level) H. On the other hand, it is installed inclined at a predetermined angle.

[0037] The inclination angle θ of the tube body 10 with respect to the horizontal plane H is about 3 to 20 degrees, particularly 5 to 15 degrees. It is preferable to set it to about . If θ is less than 3°, the bubbles will flow along the inclination of the tube body 10. It becomes difficult to move upward, and even if θ exceeds 20°, the effect will not improve any further. In fact, this is because it becomes difficult to manufacture.

[0038] Note that due to the inclination of the tubular body 10, etc., the tubular body 10 is located near the blood outflow port 7. Preferably, there is a space 51 that does not exist. As a result, blood flows from the blood outlet 7. Pressure loss during outflow is reduced, and blood circulates and stays in the blood storage space 5. can be prevented.

[0039] The heat exchanger 9 of the present invention is small and has high heat exchange efficiency. It is preferable to subject the body 10 to the following conditions.

[0040] The tube body 10 is made of a material with high thermal conductivity, such as stainless steel, aluminum, or copper. , made of metals such as titanium.

[0041] The outer diameter of the tubular body 10 (other than the reduced diameter part 101) is approximately 0.5 to 10 mm, particularly 2 to 5 mm. The inner diameter (other than the reduced diameter part 101) is preferably about 0.1 to 9.0 mm. The thickness is preferably about 1 to 4 mm.

[0042] The length (effective length) of the tubular body 10 within the blood storage space 5 is approximately 30 to 300 mm, especially In particular, it is preferably about 70 to 150 mm.

[0043] In addition, a spiral member is provided on the inner wall of the tube body 10 to generate a swirling flow in the heat medium. (not shown) may be provided.

[0044] The number of pipe bodies 10 arranged is about 10 to 2000, particularly about 50 to 1000. It is preferable that

[0045] It is preferable that the arrangement density of the tube bodies 10 is uniform throughout, and the arrangement density of the tube bodies 10 is preferably uniform throughout. The minimum gap distance between zeros (other than the reduced diameter part 101) is about 0.3 to 3.0 mm, especially when zero ．． It is preferably about 6 to 2.0 mm. If this gap distance is less than 0.3mm Blood circulation becomes difficult, and if the gap exceeds 3.0 mm, the speed of blood passing through the gap decreases. Depending on other conditions such as the number of pipes 10, heat exchange with the heat medium becomes faster. It becomes insufficient.

[0046] The inner wall 34 of the housing body 3 and the tube body 10 (reduced diameter portion 10 ) adjacent to the inner wall 34 The gap distance between the It is preferable to set it as approximately. If this gap distance is less than 0.2mm, there is no need to worry about it. Bubbles are more likely to be trapped, and if the gap exceeds 3.0 mm, blood will take priority in this gap. This causes channeling, which reduces heat exchange efficiency.

[0047] At the vertically upper end (right side in FIG. 2) of each tube 10, its outer diameter is A reduced diameter portion 101 is formed which is smaller in diameter than other parts. This allows the adjacent diameter reduction A passage 102 is formed between the portions 101 in which air bubbles can float.

[0048] The outer diameter of the reduced diameter portion 101 is about 10 to 95% of the outer diameter of the tube body 10 described above, particularly, It is preferably about 20 to 90%, specifically about 0.25 to 8.0 mm, In particular, it is preferably about 0.5 to 5.0 mm.

[0049] The inner diameter of the reduced diameter portion 101 is about 10 to 95% of the inner diameter of the tube body 10 described above, particularly, It is preferably about 20 to 90%, specifically about 0.1 to 2.5 mm, particularly about 0.1 to 2.5 mm. The thickness is preferably about 0.2 to 2.0 mm.

[0050] The minimum gap distance between adjacent reduced diameter portions 101 is approximately 0.6 to 5.0 mm, particularly, It is preferably about 1.2 to 2.5 mm. This gap distance is less than 0.6mm In this case, the area (cross-sectional area) of the passage 102 where bubbles float is not sufficiently secured, and If it exceeds 5.0 mm, the arrangement density of the tube body 10 will become coarse, and the heat exchange rate will decrease. Because it will be lowered.

[0051] The length of the reduced diameter portion 101 is approximately 1 to 30% of the effective length of the tube body 10 described above, particularly, It is preferably about 2 to 25%, specifically about 1 to 50 mm, particularly 1. It is preferably about 5 to 20 mm. The length of the reduced diameter portion 101 is the effective length of the tube body 10. If it is less than 1%, a sufficient area of the passage 102 for bubbles to float will not be secured, and , exceeds 30%, the amount of blood flowing through the passage 102 increases and the heat exchange efficiency decreases. This is because it decreases.

[0052] FIG. 5 is a partial cross-sectional side view showing another example of the structure of the tube body 10, and FIG. It is a sectional view taken along the D line. As shown in these figures, the vertically upper side of each pipe body 10 In place of the reduced diameter portion 101, a flat portion 103 having a flat shape is formed at the end of the ing.

[0053] This flat part 103 extends in the vertical direction, and the flat part 103 adjacent to the horizontal direction The shields are arranged almost parallel to each other. As a result, air bubbles are formed between adjacent flat parts 103. A path 104 is formed that can float.

[0054] In addition, when such a flat part 103 is formed in the tube body 10, the inside of the flat part 103 The cross-sectional area of the heat medium flow path 105 is approximately the same as the cross-sectional area of the flow path in other parts of the tube body 10. Since the values can be made equal, the heat medium passes through the flow path 105 in the flat part 103. There is an advantage that there is no increase in flow resistance when doing so.

[0055] The thickness T of the flat part 103 is about 10 to 95% of the outer diameter of the tube body 10 described above, especially , is preferably about 20 to 90%, specifically about 0.1 to 8.0 mm, In particular, it is preferably about 0.4 to 5.0 mm.

[0056] The gap distance S (width of the passage 104) between the horizontally adjacent flat parts 103 is 0. ．． It is preferably about 6 to 5.0 mm, particularly about 1.2 to 2.5 mm. gap distance When the separation S is less than 0.6 mm, the area (cross-sectional area) of the passage 104 where bubbles float is If the diameter is not sufficiently secured and exceeds 5.0 mm, the arrangement density of the pipe body 10 will be reduced due to this. This is because the heat exchange efficiency becomes rough and the heat exchange efficiency decreases.

[0057] The length of the flat portion 103 in the tube axis direction is 1 to 30% of the effective length of the tube 10 described above. It is preferably about 2 to 25%, specifically about 1 to 50 mm. In particular, it is preferably about 1.5 to 20 mm. The length of the flat part 103 is the length of the tube body 1 If it is less than 1% of the effective length of 0, a sufficient area of the passage 104 for bubbles to float is ensured. If it exceeds 30%, the amount of blood flowing through the passage 104 will increase, This is because heat exchange efficiency decreases.

[0058] Note that the reduced diameter portion 101 and the flat portion 103 are not formed in all the tube bodies 10. You don't have to.

[0059] Although the illustrated tube 10 has a circular cross section, the present invention is not limited to this. The cross section of 0 is a polygon such as an ellipse, a triangle, a quadrangle, a hexagon, an octagon, etc. It may be.

[0060] Such a tube body 10 has both ends connected to a pair without closing the openings at both ends. It is supported by being embedded in the partition wall 11 and fixed in a liquid-tight manner. This partition wall 11 , for example, from polymeric materials such as polyurethane, silicone rubber, and epoxy resin. Preferably, the potting material is made of a potting material. As a result, each tube body 10 is fixed. The liquid-tightness of the partition wall 11 is also maintained.

[0061] Further, the thickness of the partition wall 11 is preferably about 5 to 50 mm, more preferably about 10 mm. It is said to be about 30mm.

[0062] A heat medium supply section 12 is provided at one end of the tube body 10, and a heat medium discharge section is provided at the other end. 13 are provided.

[0063] The heat medium supply unit 12 has a housing 14 that is liquid-tightly fixed to the side surface of the housing body 3. The heat medium chamber 16 is regulated by the housing 14 and the partition wall 11. Also, the housing A tubular heat medium inlet 18 communicating with the heat medium chamber 16 is installed in 14 .

[0064] The heat medium discharge part 13 has a casing 15 that is liquid-tightly fixed to the side surface of the housing body 3. The heat medium chamber 17 is regulated by the housing 15 and the partition wall 11. Also, the housing A tubular heat medium outlet 19 communicating with the heat medium chamber 17 is installed in 15 .

[0065] The constituent materials of the housings 14 and 15 are the same as those of the housing body 3. can be mentioned.

[0066] Further, the volumes of the heat medium chambers 16 and 17 are not particularly limited, but each has a volume of 10 It is preferably about 200 ml, particularly about 30 to 150 ml.

[0067] As a heat medium, liquids such as water and alcohol that have been adjusted to a specified temperature are preferably used. However, it may also be a gas such as air.

[0068] The total amount of heat medium flowing through each tube body 10 (heat medium supply amount) is the heat medium of the heat exchanger 9. It is determined appropriately depending on the pressure loss of the body flow path, the capacity of the heat medium pump, etc., but usually 5~ It is preferably about 30 liters/minute, especially about 8 to 20 liters/minute. stomach.

[0069] Next, the function of the blood reservoir 1 will be explained. For example, blood flowing into the housing 2 from the blood inlet 6 through the blood removal line is , first passes through the foam-defoaming member 8 to be defoamed, then flows down along the slope 32 to collect blood. It is stored in space 5. In addition, a pump installed in the line connected to the blood outlet 7 Blood in the upper part of the blood storage space 5 is moved between the tube bodies 10 by suction from a tube (not shown), etc. The housing passes through the gap, the gap between the tube body 10 and the inner wall 34 of the housing body 2, etc. The blood gradually flows downward from the blood outlet 7 into the housing after reaching the space 51. 2 It flows out.

[0070] Note that blood flows through the passage 1, which is the gap between the reduced diameter portions 101 (or the flattened portions 103). 02 (or 104) also flows, but these are formed in a part of the entire length of the pipe body 10. Since the amount of blood flowing through this passage 102 is small, the channel There is almost no decrease in heat exchange efficiency due to cooling.

[0071] On the other hand, when the heat medium is supplied to the heat medium chamber 16 from the heat medium inlet 18, this heat medium passes through each pipe body 10 and the heat medium chamber 17 sequentially, and is discharged from the heat medium outlet 19. . When the heat medium passes through each tube 10, the heat medium and blood pass through the tube wall of the tube 10. Heat exchange is performed between the blood storage space 5 and the blood in the blood storage space 5 to warm or cool the blood.

[0072] For example, in the case of a blood storage tank 1 installed in an extracorporeal blood circulation circuit, a heat medium is used during surgery. The temperature of the blood is cooled to about 20℃ using cold water, and at the end of the surgery, a heat medium is used. The operation of heating the blood at about 20°C to bring it back to body temperature using warm water. Do the following.

[0073] Prior to starting such blood circulation, saline is introduced into the blood circulation circuit. Prime with a priming solution such as Priming liquid to blood storage space 5 The injection is performed, for example, through the blood inlet 6.

[0074] Air bubbles generated during priming operation or air mixed in the priming liquid in advance When priming the blood storage space 5, bubbles are formed in the space 51, the gaps between the tube bodies 10, and The bubble enters the gap between the tube body 10 and the inner wall 34, but due to its buoyancy, the bubble tilts. It naturally moves obliquely upward (to the right in FIG. 2) along each tube 10, and vertically moves along each tube 10. Gather in the upper direction. As a result, the bubbles combine to form large bubbles, which creates buoyancy. increases. Furthermore, this bubble rises through passage 102 (or 104) and The bubbles float to the surface of the liming liquid (above each tube 10) and break.

[0075] In this way, most of the bubbles in the priming liquid in the blood storage space 5 are removed. It is discharged without being retained. Also, even if there are residual air bubbles, the blood reservoir should not be vibrated. The bubbles can be easily expelled in the same manner as described above by applying vibration or shaking.

[0076] The above is a description of the illustrated configuration example of the heat exchanger of the present invention and the blood storage tank equipped with the same. However, the present invention is not limited thereto.

[0077] Note that the heat exchanger of this invention is not limited to being incorporated into a blood storage tank; it can also be used as a standalone heat exchanger. It can also be applied to what you use. As such a heat exchanger, for example, In the oxygenator extracorporeal blood circulation circuit, it is installed between the blood storage tank (without heat exchanger) and the oxygenator. For example, a heat exchanger installed in the

[0078]

【Example】

Hereinafter, specific embodiments of the present invention will be described. (Example 1) Blood reservoirs having the configurations shown in FIGS. 1, 2, 3, and 4 were prepared. The conditions for each part of the blood storage tank are as follows: It is as follows. Housing volume: 4000ml Volume of the pipe installation part and the space below it: 200ml in total Housing material: Polycarbonate (transparent) Partition wall material: Polyurethane (two-component mixture type) Defoaming member: Polyurethane foam (pore diameter 1000μm) Pipe shape: Straight pipe with circular cross section Tube material: stainless steel Tube inner diameter: 2.00mm Pipe outer diameter: 2.38mm Tube length: 116mm (effective length 78mm) Number of tubes installed: 405 Pipe installation angle (angle of inclination with respect to horizontal plane): θ = 10° Minimum gap distance between adjacent pipes: 0.9mm Gap distance between housing inner wall and adjacent pipe body: 0.5mm Inner diameter of reduced diameter part of tube body: 0.5mm Outer diameter of reduced diameter part of tube body: 1.0mm Length of tube body diameter reduction part: 2.0mm Minimum gap distance between adjacent reduced diameter parts: 2.28mm Housing material: Polycarbonate (transparent) Heat medium chamber volume (heat medium supply side): 100ml Heat medium chamber volume (heat medium discharge side): 100ml

[0079] (Example 2) Except that the tube installation angle θ was 15° and the dimensions of the reduced diameter part of each tube were as follows. prepared a blood reservoir similar to that in Example 1 above. Inner diameter of reduced diameter part of tube body: 0.3mm Outer diameter of tube body reduced diameter part: 0.8mm Length of tube body diameter reduction part: 2.5mm Minimum gap distance between adjacent reduced diameter parts: 2.48mm

(Example 3) A blood reservoir similar to that of Example 1 was produced, except that instead of the diameter-reduced portion, a tubular body having a flattened portion having the structure shown in FIGS. 5 and 6 was used. The dimensions of the flat part were as follows. Tube flat part thickness T: 1.0 mm Tube flat part length: 2.0 mm Cross-sectional area of channel in flat part: 4.0 mm Gap distance S between ^two horizontally adjacent flat parts: 2.28 mm

[0081] (Comparative example 1) Each pipe is installed horizontally (tube installation angle θ = 0), and each pipe has a reduced diameter part and a flat part. A blood reservoir similar to that of Example 1 above was prepared except for the difference.

[0082] (Comparative example 2) The above except that the gap distance between the inner wall of the housing and the adjacent pipe body was 1.5 mm. A blood reservoir similar to that of Comparative Example 1 was prepared.

Experiment 1 A priming solution (physiological saline) was injected into the blood storage space from the blood outlet of each of the blood storage tanks of Examples 1, 2, and 3 and Comparative Examples 1 and 2 above. This priming liquid contained minute air bubbles with a diameter of about 1 to 3 mm.

[0084] Visual observation of the state of the bubbles revealed that the blood reservoirs of Examples 1, 2, and 3 In this case, about 95% of the bubbles move obliquely upward along each inclined tube, and further A small amount of air bubbles floats up through the passage between the reduced diameter part or the flat part, and a small amount of air bubbles are formed on the inner wall of the housing or It was attached to the tube surface. In addition, in the blood storage tank of Comparative Example 1, most of the bubbles were Below the body, gaps between tubes, and gaps between the inner wall of the housing and adjacent tubes In the blood reservoir of Comparative Example 2, air remains below the tubes and in the gaps between the tubes. Bubbles remained.

[0085] Next, vibrate each blood reservoir and visually observe how well the air bubbles come out. The gender was evaluated. The results are shown in Table 1 below.

[0086] Note that the evaluation of air bubble removal properties in Table 1 is as follows. ○: No bubbles remaining △: Some air bubbles remain ×: There are quite a lot of bubbles remaining.

Experiment 2 For each of the above blood storage tanks, while maintaining the blood storage volume of 2000 ml, 20°C bovine blood (Ht = 12 g/dl) was supplied into the blood storage space from the blood inlet at a flow rate of 4000 ml/min. A tube and a roller pump were connected to the blood outlet side, and the same amount of blood as the supplied amount was discharged from the blood outlet.

[0088] On the other hand, at the same time as the inflow and outflow of blood, the heat medium flows from the heat medium inlet. water at a temperature of 37°C is supplied at a flow rate of 15,000 ml/min, and the blood in the blood storage space is pumped through each tube. The liquid was heated.

[0089] After 15 minutes from the start of the above operation, measure the temperature of the blood flowing out from the blood outlet. The heat exchange performance of the heat exchanger was then investigated. The results are shown in Table 1 below. In addition, Table 1 In this case, the temperature of the blood flowing out from the blood outlet (heat exchange performance) is the temperature of the heat medium ( 37° C.), the higher the heat exchange efficiency of the heat exchanger.

[0090]

[Table 1]

[0091] As shown in Table 1 above, in the blood reservoirs of Examples 1, 2 and 3 of the present invention, air bubbles were removed. It has excellent heat exchange properties and high heat exchange efficiency of the heat exchanger.

[0092] On the other hand, in the blood storage tank of Comparative Example 1, although the heat exchange efficiency of the heat exchanger is high, On the other hand, the blood storage tank of Comparative Example 2 has almost good air bubble removal properties, but The heat exchange efficiency of the exchanger is low.

[0093]

[Effect of the idea]

As described above, the heat exchanger of the present invention and the blood storage tank equipped with the same For example, it has excellent ability to remove air bubbles, especially minute air bubbles that get mixed in during priming. High heat exchange rate.

[Brief explanation of drawings]

FIG. 1 is a perspective view showing an example of the configuration of a blood reservoir according to the present invention.

FIG. 2 is a cross-sectional view taken along line AA in FIG. 1.

FIG. 3 is a sectional view taken along line BB in FIG. 2;

FIG. 4 is a sectional view taken along line CC in FIG. 2;

FIG. 5 is a partially sectional side view showing another example of the structure of the tube according to the present invention.

6 is a sectional view taken along line DD in FIG. 5. FIG.

[Explanation of symbols]

1 Blood storage tank 2 Housing 3 Housing body 31 Projection 32 Slope 33 Rib 34 Inner wall 4 Lid body 5 Blood storage space 51 Space 6 Blood inlet 7 Blood outlet 8 Defoaming member 9 Heat exchanger 10 Tube body 101 Reduced diameter part 102 Passage 103 Flat part 104 Passage 105 Flow path 11 Bulkhead 12 Heat medium supply section 13 Heat medium discharge part 14, 15 Housing 16, 17 Heat medium room 18 Heat medium inlet 19 Heat medium outlet H horizontal plane

Claims (4)

[Scope of utility model registration request] 1. A housing having a blood storage space formed therein, a blood inlet and a blood outlet communicating with the blood storage space, and a plurality of housings constructed within the blood storage space and mainly consisting of straight pipe sections. A heat exchanger comprising a tube body, a heat medium supply section that supplies a heat medium into the tube body, and a heat medium discharge section that discharges the heat medium that has passed through the tube body, A heat exchanger characterized in that a pipe section is installed to be inclined with respect to a horizontal plane, and the outer diameter of the vertically upper end of the inclined straight pipe section is reduced. 2. A housing having a blood storage space formed therein, a blood inlet and a blood outlet communicating with the blood storage space, and a plurality of tubes constructed within the blood storage space and mainly composed of straight pipe sections. A heat exchanger comprising a heat medium supply section that supplies a heat medium into the tube body, and a heat medium discharge section that discharges the heat medium that has passed through the tube body, the heat exchanger comprising a straight tube of each tube body. 1. A heat exchanger characterized in that the section is installed to be inclined with respect to a horizontal plane, and the vertically upper end of the inclined straight pipe section has a flat shape. 3. Each of the tube bodies is a straight tube arranged in parallel, and both ends of each straight tube are supported by partition walls without closing the openings at both ends of each straight tube. Heat exchanger described in. 4. A blood storage tank comprising the heat exchanger according to claim 1.