JPH03171032A - Washing method and device therefor - Google Patents

Abstract

PURPOSE:To improve washing efficiency by sealing liberated deposits into a hydrophilic gel or colloidal sol by electrophoresis. CONSTITUTION:The deposits of protein and inorg. matter sticking to a lens 10 are removed by utilizing the electrolytic effect of an acidic treatment. The deposits electrolyzed by the electrophoresis in the hydrophilic gel or colloidal sol are drawn out and sealed into the gel by energization. For example, a 1st vessel 1 made of a synthetic resin is previously bored with plural small holes 14 for increasing the contact area of a buffer sol. and the gel. After the contact lens 10 as a body to be washed is perpendicularly held by a lens holding body 6, the holding body 6 is imposed into the 1st vessel 1 and the hydrophilic gel or colloidal sol as an electrophoresis member P is put into the vessel 1. The 1st vessel 1, a pair of electrode plates 12, 13 and a washing liquid Q are put into a 2nd vessel 11 made of a synthetic resin having a cap body 11A. The lens is rapidly washed in this way without damaging the lens and the washing efficiency is enhanced.

Description

Detailed Description of the Invention (Industrial Application Field) The present invention relates to contact lenses, intraocular lenses, spectacle lenses,
This article relates to a cleaning method and device for cleaning medical optical lenses, etc. (Conventional Technique 1#) Conventional methods for cleaning medical optical lenses, especially contact lenses, include cleaning by hand with a solution containing a surfactant or applying ultrasound or heat to the solution. 53-1
No. 6629) and a method for disinfection by passing an electric current through saline water to create hypochlorite (Special Publication No. 60-2055)
No.), or a method of separating the electrolytic solution into acid and alkaline solutions using an ion exchange membrane and cleaning with the alkaline solution and ultrasonic waves (Japanese Patent Application Laid-open No. 63-254417), and also. Commonly known as enzyme treatment agents (which mainly contain proteolytic enzymes and ionolytic enzymes)
There is a cleaning method using JP-A-50-31834, JP-A-50-64303, JP-A-57-48712). (Problems to be Solved by the Invention) As mentioned above, in the past, washing hands with surfactants was not very effective and often caused damage or damage to the lenses themselves. Furthermore, even when an ultrasonic cleaner was used, cavitation effects were observed, but proteins, mainly lysozyme, were not removed. In addition, even in methods that focus on ionization, there are difficulties in liberating the lysozyme layer. On the other hand, when it comes to enzyme treatment agents, the higher the temperature of the solution, for example around 6
Although it is said that a temperature around 0°C is preferable for its activity, most of its uses are carried out at room temperature, and it cannot be sufficiently effective. Furthermore, in each of the above-mentioned methods, even if the adhering matter is dissolved and removed, the current situation is that no consideration is given to the re-adhesion of the substance. In view of the above-mentioned problems, the present invention utilizes electrophoresis to quickly clean proteins, inorganic substances, etc. that have adhered to lenses that have become dirty due to wear, without having to touch the lenses with hands or fingers during cleaning, without damaging the lenses. The purpose of this invention is to provide a cleaning method and device that enhances the cleaning effect while taking into account the adverse effects on the eyes due to re-deposition. (Means for Solving the Problems) Accordingly, in the present invention, free deposits are sealed in a hydrophilic gel or colloid sol by electrophoresis to prevent re-deposition to optical lenses, etc., and improve the cleaning effect. It's as intimidating as possible. (Function) Utilizes the electrolysis effect caused by acidic treatment to remove protein and inorganic deposits attached to the lens, and removes deposits electrolyzed by electrophoresis in hydrophilic gels and colloidal sol by applying electricity. The gel is pulled out and sealed in the gel to prevent the removed adhesion from re-adhering, and to perform cleaning efficiently. (Example) In the example shown in Figures 1 to 5, 1 is a first container made of Hewei resin, and the side wall surfaces 2 and 3 are designed to increase the contact area between the buffer solution and the gel. Multiple small holes 4 are drilled in the hole. The number of the small holes 4 is preferably 5 or more per 1 square cm, and considering the effect, the diameter is 0.5 mm to 3.5 mm. O
Preferably around mm. Note that the number and diameter of the small holes 4 are not limited. 5 is a paper-like material that does not affect conductivity, and 2t paper is placed on the side walls 2 and 3 of the container 1 described above. This is to prevent leakage of the electrophoretic material, which will be described later. It goes without saying that the side wall surfaces 2 and 3 of the first container 1 having the small holes 4 formed therein may be replaced with the mesh member 4A. (See Fig. 2(b)) Reference numeral 6 denotes a lens holder made of synthetic resin, which is composed of a base plate 7 and a pair of U-shaped holding arms 8 that are rotatable left and right.
The slit 9 of the holding arm 8 is designed to hold a contact lens 10 as a lens body. After the contact lens 10 as a dirty object to be cleaned is vertically held by the lens holder 6, the holder 6 is placed in the first container 1. The above-mentioned holding arm 8 is designed to be rotatable 3,600 degrees in order to enable the user to freely select the positive (+) and negative (-) poles of the electrode plate, which will be described later. After placing the above-mentioned holder 6 in the first container 1, a hydrophilic gel or colloidal sol as the electrophoretic member P is placed in the container 1. Therefore, the surface toa of the contact lens 10. g side 10
B is in close contact with the electrophoretic member P. (Figure 4,
(See Figure 5) The hydrophilic gel or colloidal sol as the electrophoretic member P mentioned above includes polyacrylic acid, amidomethyl cellulose,
Ethyl cellulose, hydroxyethyl acrylate, hydroxyprobyl acrylate, CMC (carpoxymethyl methacrylate). HEMA (hydroxyethyl methacrylate), dihydroxyethyl methacrylate
, AGAR (agar), starch gel, etc. These electrophoretic members PI:II! By doing so (fluid state), it becomes easier for the adhering matter attached to the lens body to move into the gel, and it becomes easier to conduct electricity. In addition, the anionic surfactant that is the electrophoresis member P has the function of cutting protein bonds, and a specific example thereof is SDS.
(sodium lauryl sulfate). This SDS charges the attached protein as an anion and decomposes it. Furthermore, the chelating agent that is the electrophoretic member P has the function of incorporating inorganic substances into the gel, and a specific example thereof is E.
DTA-2Na (disodium ethylenediaminetetraacetic acid), CYDTA (cyclohexanediaminetetraacetic acid),
DE-TAPAC (diethylenetriaminopentaacetic acid)
．． The gel contains bile acids such as Ampotin, cholic acid, and deoxycholic acid. Furthermore, β is a reducing substance for proteins in the electrophoretic member P.
-Mercaptoethanol, dithiothreitol, etc. Therefore, the above-mentioned gel components include an anionic surfactant,
Contains chelating agents, acidic buffers, etc. Reference numeral 11 denotes a second container made of synthetic resin that holds the lid 11A, and has various shapes such as square and elliptical.
2.13) and cleaning solution Q. The cleaning solution Q uses an acidic buffer, which has the function of converting bonded deposits attached to the lens body into free deposits, and also contains the same buffer as the buffer contained in the gel described above. Since it is a buffer solution, it aids in the cleaning action of the gel (in the buffer solution). Specific examples of buffer solutions include Tris-HCl buffer,
Sodium acetate hydrochloride buffer, disodium hydrogen phosphate,
Examples include citrate buffer, Tris/Tris hydrochloride buffer, and various other buffers. The electrode plate (12.13) described above is made of highly durable platinum, silver chloride, or the like. The voltage applied to this electrode plate (12.13) is DC2V~1
It is 00■. The energization time is 30 minutes to 4 hours, preferably about 2 hours. A lens body such as the contact lens 10 described above and an electrode plate (
12.13) means the surface 10 of the lens body as shown in Figure 4.
A. The electrode plate (12.13) is arranged so as to be substantially perpendicular and perpendicular to the back surface 10B. In addition, the electrode plate (1
2.13) may of course be arranged parallel to the side wall surfaces 2 and 3 as shown in FIG. However, even in this case, the lens body must be at right angles to the electrode plates (l2, 13) as shown in FIG. In other words, the electrode plate (12.13) is arranged at a position of approximately 90° and perpendicular to the front and back surfaces (10A, IOB) of the lens body, and whether the attached material is polarized in the positive or negative direction. Also, the front and back surfaces of the lens body (10A, 10
This is to allow movement on any surface of B). By shortening the distance between the electrode plate (12.13) and the gel and lens body, the electrical resistance due to the buffer solution can be reduced and cleaning efficiency can be improved. Additionally, the entire container can be made compact and portable. 14 is a third container containing cooling water W or gel-like endothermic coolant WA. This is the same as the first and second containers (1.1
1) This is to remove the heat generated during electrophoresis in the gel to increase the speed of electrophoresis and to prevent swelling of the gel and impact on the lens body. Usually, the water is designed to be lukewarm at 30'-40'C. In addition, this cooling water W9.
It is of course possible to use other cooling means instead of the agent WA, such as an electronic cooling device, a fin mechanism for air cooling, a fan mechanism for flowing cooling air, or a gas circulation mechanism that uses other cooling gas. be. Next, we will explain how the device of the present invention is used. The lens body is supported by the lens holder 6 and placed in the first container l, and the paper 5 is inserted inside the side wall surface (2.3) of the container 1 in which the small hole 4 is made. Thereafter, the loosened electrophoretic member P is filled into the container l, and the lens body and the electrophoretic member P are brought into close contact.
Next, the container 1 is placed in the second container 11, and a pair of electrode plates (12.13) are placed on the front and back surfaces of the lens body (10A, IO
A third container 1 is disposed perpendicularly and perpendicularly to B) (see Figures 4 and 5) and into which the cleaning liquid Q is poured.
4. Inject cooling water W or endothermic coolant WA. After that, DC voltage is applied to the electrode plate (12.13) to energize it. At that time, V
: Electrolyze the adhesion on the lens body using an Il solution. Furthermore, the decomposition power is increased with the same buffer solution in which the lens body is immersed, and the dissolved deposits are sealed in the gel by the electrophoretic force to prevent the released deposits from re-attaching to the lens body. It is for cleaning. (Effects of the Invention) Since the present invention has the configuration as described above, it has the following effects. (a) Since an electrophoretic material such as a hydrophilic gel or colloidal sol is brought into close contact with the lens body, it is possible to enhance the electrification effect on proteins, liquid extracts, inorganic substances, etc. attached to the lens body. (b) Since an acidic buffer solution is used, the bound substance adhering to the lens body is changed to a free form, making it easier for the adhesion substance to separate from the lens body. (C) Also, since the electrophoretic member is brought into close contact with the lens body, the entire device can be made extremely compact.
Convenient to carry. (d) Since the electrophoretic member is brought into close contact with the lens body, the lens body can be cleaned without touching the lens body with fingers, so there is no possibility of damaging or damaging the lens body.

[Brief explanation of the drawing]

FIG. 1 is a perspective view of the apparatus of the present invention, FIG. 2(a) is a perspective view of a first container, and FIG. 2(b) is a perspective view of another embodiment. Fig. 3 is a perspective view showing the arrangement relationship between the first container and a pair of electrodes, Fig. 4 is a plan view of the device of the present invention, Fig. 5 is a vertical cross-sectional front view of Fig. 4, and Fig. 6 is a lens holder. It is a perspective view of the body. FIG. 7 is a plan view of another embodiment showing the relationship between the electrode plate, the lens body, and the side wall surface. 1... First container 6... Lens holder 10●●
●Contact lens P●●●Electrophoretic material 1l
●●●Second container 12.13●●・Electrode plate Q・
...Washing liquid W...Cooling water WA...Endothermic coolant Fig. 4

Claims (1)

[Claims] (1) Electrophoretic member P such as hydrophilic gel or colloidal sol
is brought into close contact with the object to be cleaned, immersed in a buffer solution constituting the cleaning solution Q, and then energized to cause electrophoresis to liberate the adherents from the object to be cleaned. Method (2) Electrophoretic member P such as hydrophilic gel or colloidal sol
is brought into close contact with the lens body, immersed in a buffer solution constituting the cleaning solution Q, and by applying electricity, the deposits on the lens body are released with electrophoresis and are sealed and stopped in the electrophoresis member P. A cleaning method characterized by cleaning the lens body while preventing re-adhesion to the lens body (3) Electrophoretic member P such as hydrophilic gel or colloidal sol
is brought into close contact with the lens body, immersed in a buffer solution constituting the cleaning solution Q, and the lens body is placed between a pair of electrode plates, with the front and back surfaces of the lens body being approximately perpendicular to the electrode plates. A cleaning method (4) in which, by positioning the lens vertically and energizing it, deposits on the lens body are released through electrophoresis and sealed in the electrophoretic member P, while cooling the cleaning liquid Q. A lens body and an electrophoretic member P are placed in a first container 1 having a through hole, and the container 1
is placed between the pair of electrode plates (12, 13) in the second container 11 and the cleaning liquid Q is placed therein, while the second container 11 is placed in a third container containing the cooling water W or the endothermic coolant WA. A cleaning device (5) placed in the electrode plate (12, 13) and configured to release deposits from the lens body through electrophoresis by applying electricity to the electrode plate (12, 13) and the lens body. The cleaning device (6) according to claim (4), wherein the electrode plates (12, 13) are arranged so as to be substantially perpendicular to and perpendicular to the front and back surfaces (10A, 10B) of the lens body. Claims (2) to (5) wherein the lens body is a contact lens 10.
Cleaning equipment described