JPH03130051A - Functional food - Google Patents
Functional foodInfo
- Publication number
- JPH03130051A JPH03130051A JP1187906A JP18790689A JPH03130051A JP H03130051 A JPH03130051 A JP H03130051A JP 1187906 A JP1187906 A JP 1187906A JP 18790689 A JP18790689 A JP 18790689A JP H03130051 A JPH03130051 A JP H03130051A
- Authority
- JP
- Japan
- Prior art keywords
- oil
- capsule
- natural
- gymnema
- soluble polymer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 235000013376 functional food Nutrition 0.000 title claims description 11
- 239000002775 capsule Substances 0.000 claims abstract description 25
- 239000000203 mixture Substances 0.000 claims abstract description 14
- 229920003169 water-soluble polymer Polymers 0.000 claims abstract description 13
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical class CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims abstract description 8
- 241000208251 Gymnema Species 0.000 claims description 16
- 150000003839 salts Chemical class 0.000 claims description 5
- 150000007524 organic acids Chemical class 0.000 claims description 3
- 241000208253 Gymnema sylvestre Species 0.000 abstract description 23
- 239000003921 oil Substances 0.000 abstract description 18
- 235000019198 oils Nutrition 0.000 abstract description 18
- 235000019658 bitter taste Nutrition 0.000 abstract description 6
- 239000000796 flavoring agent Substances 0.000 abstract description 5
- 235000019634 flavors Nutrition 0.000 abstract description 5
- 244000215068 Acacia senegal Species 0.000 abstract description 4
- 229920000084 Gum arabic Polymers 0.000 abstract description 4
- 235000010489 acacia gum Nutrition 0.000 abstract description 4
- 239000000205 acacia gum Substances 0.000 abstract description 4
- 239000004373 Pullulan Substances 0.000 abstract description 3
- 229920001218 Pullulan Polymers 0.000 abstract description 3
- 235000019485 Safflower oil Nutrition 0.000 abstract description 3
- 235000013305 food Nutrition 0.000 abstract description 3
- 239000004615 ingredient Substances 0.000 abstract description 3
- 235000019423 pullulan Nutrition 0.000 abstract description 3
- 235000005713 safflower oil Nutrition 0.000 abstract description 3
- 239000003813 safflower oil Substances 0.000 abstract description 3
- 229920001817 Agar Polymers 0.000 abstract description 2
- 239000008272 agar Substances 0.000 abstract description 2
- 235000010419 agar Nutrition 0.000 abstract description 2
- 239000005018 casein Substances 0.000 abstract description 2
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 abstract description 2
- 235000021240 caseins Nutrition 0.000 abstract description 2
- 238000002156 mixing Methods 0.000 abstract 2
- YYGNTYWPHWGJRM-UHFFFAOYSA-N (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene Chemical compound CC(C)=CCCC(C)=CCCC(C)=CCCC=C(C)CCC=C(C)CCC=C(C)C YYGNTYWPHWGJRM-UHFFFAOYSA-N 0.000 abstract 1
- BHEOSNUKNHRBNM-UHFFFAOYSA-N Tetramethylsqualene Natural products CC(=C)C(C)CCC(=C)C(C)CCC(C)=CCCC=C(C)CCC(C)C(=C)CCC(C)C(C)=C BHEOSNUKNHRBNM-UHFFFAOYSA-N 0.000 abstract 1
- DTOSIQBPPRVQHS-PDBXOOCHSA-N alpha-linolenic acid Chemical compound CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O DTOSIQBPPRVQHS-PDBXOOCHSA-N 0.000 abstract 1
- 235000020661 alpha-linolenic acid Nutrition 0.000 abstract 1
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N dodecahydrosqualene Natural products CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 abstract 1
- 229960004488 linolenic acid Drugs 0.000 abstract 1
- KQQKGWQCNNTQJW-UHFFFAOYSA-N linolenic acid Natural products CC=CCCC=CCC=CCCCCCCCC(O)=O KQQKGWQCNNTQJW-UHFFFAOYSA-N 0.000 abstract 1
- 229940031439 squalene Drugs 0.000 abstract 1
- TUHBEKDERLKLEC-UHFFFAOYSA-N squalene Natural products CC(=CCCC(=CCCC(=CCCC=C(/C)CCC=C(/C)CC=C(C)C)C)C)C TUHBEKDERLKLEC-UHFFFAOYSA-N 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 9
- 230000000694 effects Effects 0.000 description 7
- 239000011248 coating agent Substances 0.000 description 6
- 239000000284 extract Substances 0.000 description 6
- 239000000047 product Substances 0.000 description 6
- 241000196324 Embryophyta Species 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 239000008280 blood Substances 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- 239000008213 purified water Substances 0.000 description 4
- 229920001353 Dextrin Polymers 0.000 description 3
- 239000004375 Dextrin Substances 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 3
- 239000010775 animal oil Substances 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 235000019425 dextrin Nutrition 0.000 description 3
- 239000006185 dispersion Substances 0.000 description 3
- 239000000839 emulsion Substances 0.000 description 3
- 235000008524 evening primrose extract Nutrition 0.000 description 3
- 239000010475 evening primrose oil Substances 0.000 description 3
- 229940089020 evening primrose oil Drugs 0.000 description 3
- -1 furcellulan Polymers 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 235000015112 vegetable and seed oil Nutrition 0.000 description 3
- 239000008158 vegetable oil Substances 0.000 description 3
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 description 2
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 2
- JLPULHDHAOZNQI-ZTIMHPMXSA-N 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCC\C=C/C\C=C/CCCCC JLPULHDHAOZNQI-ZTIMHPMXSA-N 0.000 description 2
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 description 2
- 108010010803 Gelatin Proteins 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 2
- 244000269722 Thea sinensis Species 0.000 description 2
- 241000209140 Triticum Species 0.000 description 2
- 235000021307 Triticum Nutrition 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 239000003513 alkali Substances 0.000 description 2
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 239000000084 colloidal system Substances 0.000 description 2
- 238000007796 conventional method Methods 0.000 description 2
- 230000002255 enzymatic effect Effects 0.000 description 2
- 239000008273 gelatin Substances 0.000 description 2
- 229920000159 gelatin Polymers 0.000 description 2
- 235000019322 gelatine Nutrition 0.000 description 2
- 235000011852 gelatine desserts Nutrition 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 239000001630 malic acid Substances 0.000 description 2
- 235000011090 malic acid Nutrition 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 238000004080 punching Methods 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 229940083466 soybean lecithin Drugs 0.000 description 2
- 235000019640 taste Nutrition 0.000 description 2
- 230000008719 thickening Effects 0.000 description 2
- 239000010497 wheat germ oil Substances 0.000 description 2
- JQWAHKMIYCERGA-UHFFFAOYSA-N (2-nonanoyloxy-3-octadeca-9,12-dienoyloxypropoxy)-[2-(trimethylazaniumyl)ethyl]phosphinate Chemical compound CCCCCCCCC(=O)OC(COP([O-])(=O)CC[N+](C)(C)C)COC(=O)CCCCCCCC=CCC=CCCCCC JQWAHKMIYCERGA-UHFFFAOYSA-N 0.000 description 1
- 241000252073 Anguilliformes Species 0.000 description 1
- 241000208327 Apocynaceae Species 0.000 description 1
- 241001474374 Blennius Species 0.000 description 1
- 108010076119 Caseins Proteins 0.000 description 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 1
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 description 1
- 108010082495 Dietary Plant Proteins Proteins 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 208000004930 Fatty Liver Diseases 0.000 description 1
- 108010068370 Glutens Proteins 0.000 description 1
- 244000068988 Glycine max Species 0.000 description 1
- 235000010469 Glycine max Nutrition 0.000 description 1
- 229920002907 Guar gum Polymers 0.000 description 1
- 241001670157 Gymnura Species 0.000 description 1
- 206010019708 Hepatic steatosis Diseases 0.000 description 1
- 229920000161 Locust bean gum Polymers 0.000 description 1
- 229920000715 Mucilage Polymers 0.000 description 1
- 241000772415 Neovison vison Species 0.000 description 1
- 108010073771 Soybean Proteins Proteins 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 240000004584 Tamarindus indica Species 0.000 description 1
- 235000004298 Tamarindus indica Nutrition 0.000 description 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 1
- 229930003427 Vitamin E Natural products 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 238000004220 aggregation Methods 0.000 description 1
- 230000002776 aggregation Effects 0.000 description 1
- 239000005456 alcohol based solvent Substances 0.000 description 1
- 235000010443 alginic acid Nutrition 0.000 description 1
- 239000000783 alginic acid Substances 0.000 description 1
- 229920000615 alginic acid Polymers 0.000 description 1
- 229960001126 alginic acid Drugs 0.000 description 1
- 150000004781 alginic acids Chemical class 0.000 description 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 210000001557 animal structure Anatomy 0.000 description 1
- 230000000170 anti-cariogenic effect Effects 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 235000021302 avocado oil Nutrition 0.000 description 1
- 239000008163 avocado oil Substances 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 235000010418 carrageenan Nutrition 0.000 description 1
- 239000000679 carrageenan Substances 0.000 description 1
- 229920001525 carrageenan Polymers 0.000 description 1
- 229940113118 carrageenan Drugs 0.000 description 1
- 235000013339 cereals Nutrition 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 229960001231 choline Drugs 0.000 description 1
- OEYIOHPDSNJKLS-UHFFFAOYSA-N choline Chemical compound C[N+](C)(C)CCO OEYIOHPDSNJKLS-UHFFFAOYSA-N 0.000 description 1
- 235000020971 citrus fruits Nutrition 0.000 description 1
- 230000009194 climbing Effects 0.000 description 1
- 239000003240 coconut oil Substances 0.000 description 1
- 235000019864 coconut oil Nutrition 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 238000013329 compounding Methods 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 238000007598 dipping method Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 210000002969 egg yolk Anatomy 0.000 description 1
- 235000013345 egg yolk Nutrition 0.000 description 1
- 238000005538 encapsulation Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 208000010706 fatty liver disease Diseases 0.000 description 1
- 235000007983 food acid Nutrition 0.000 description 1
- 235000003599 food sweetener Nutrition 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 239000001530 fumaric acid Substances 0.000 description 1
- 235000011087 fumaric acid Nutrition 0.000 description 1
- 229940098330 gamma linoleic acid Drugs 0.000 description 1
- VZCCETWTMQHEPK-UHFFFAOYSA-N gamma-Linolensaeure Natural products CCCCCC=CCC=CCC=CCCCCC(O)=O VZCCETWTMQHEPK-UHFFFAOYSA-N 0.000 description 1
- VZCCETWTMQHEPK-QNEBEIHSSA-N gamma-linolenic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/CCCCC(O)=O VZCCETWTMQHEPK-QNEBEIHSSA-N 0.000 description 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 1
- 235000021312 gluten Nutrition 0.000 description 1
- 239000000665 guar gum Substances 0.000 description 1
- 235000010417 guar gum Nutrition 0.000 description 1
- 229960002154 guar gum Drugs 0.000 description 1
- 229930183009 gymnemic acid Natural products 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 229940119170 jojoba wax Drugs 0.000 description 1
- 229940025902 konjac mannan Drugs 0.000 description 1
- 239000000787 lecithin Substances 0.000 description 1
- 235000010445 lecithin Nutrition 0.000 description 1
- 229940067606 lecithin Drugs 0.000 description 1
- 235000010420 locust bean gum Nutrition 0.000 description 1
- 239000000711 locust bean gum Substances 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 150000007522 mineralic acids Chemical class 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- 239000001814 pectin Substances 0.000 description 1
- 235000010987 pectin Nutrition 0.000 description 1
- 229920001277 pectin Polymers 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 230000002787 reinforcement Effects 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
- 239000001488 sodium phosphate Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000000638 solvent extraction Methods 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 239000003549 soybean oil Substances 0.000 description 1
- 235000012424 soybean oil Nutrition 0.000 description 1
- 235000019710 soybean protein Nutrition 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 231100000240 steatosis hepatitis Toxicity 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
- 229910000406 trisodium phosphate Inorganic materials 0.000 description 1
- 235000019801 trisodium phosphate Nutrition 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 238000003809 water extraction Methods 0.000 description 1
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 description 1
Landscapes
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
Description
【発明の詳細な説明】
[産業上の利用分野]
本発明は機能性食品として有用なカプセルを提供するも
のである。DETAILED DESCRIPTION OF THE INVENTION [Industrial Field of Application] The present invention provides a capsule useful as a functional food.
[従来の技術]
ギムネマは、血糖値上昇制御作用をもち、いわゆる糖尿
症の治療に有用な物質である。[Prior Art] Gymnema has a blood sugar level increase control effect and is a substance useful in the treatment of so-called diabetes.
ギムネマを他の茶製品あるいは薬用植物と併用し、お茶
の様に使用する方法とギムネマを抽出分離したエキスや
成分等を用いて錠剤化された物が提供されている。これ
らの、使用形態ではギムネマ特有の苦み、風味成分によ
り長期間摂取することが困難である。There are methods of using gymnema in combination with other tea products or medicinal plants to use it like tea, and products made into tablets using extracts and ingredients extracted and separated from gymnema. In these usage forms, it is difficult to ingest gymnema for a long period of time due to its unique bitterness and flavor components.
[発明が解決しようとする課題]
ギムネマは、特有の味質を有する物質であり、ギムネマ
を口に入れ噛んだ後、甘味剤を飲しても甘さを感しさせ
ない特徴が有る植物である。しかしギムネマには、特有
の苦み成分や風味等のため、気柱に飲むのには少し抵抗
となっている。[Problem to be solved by the invention] Gymnema is a substance with a unique taste, and it is a plant that has the characteristic that even if you put it in your mouth and chew it, you will not feel the sweetness even if you drink a sweetener. . However, gymnema has a unique bitterness and flavor, which makes it a bit difficult to drink it in the air.
ギムネマを熱水抽出、アルコール系溶媒での抽出等の方
法で得られたエキスや、ギムネマ葉の粉末物を錠剤化し
た物であっても口中に入れると錠剤中のギムネマ成分が
溶出し、味覚を抑制したり苦味性のため長期間の服用が
出来ない。Even if you have an extract obtained from gymnema by hot water extraction or alcohol-based solvent extraction, or a tablet made from powdered gymnema leaves, when you put it in your mouth, the gymnema ingredients in the tablet will dissolve and the taste will be affected. It cannot be taken for a long period of time due to its bitter taste.
ギムネマは血糖値上昇抑制作用、抗う蝕性作用等優れた
薬理作用を保持しているにもかかわらず、上記の理由に
より使用が制限されている。血糖値上昇を抑制するため
には長期間の飲用することが不可能であり、ギムネマの
苦味性が強い機能性食品及び医薬品としての適用に大き
な妨げとなっている。Although gymnema has excellent pharmacological effects such as blood sugar level increase suppressing effect and anti-cariogenic effect, its use is restricted for the above reasons. It is impossible to drink gymnema for a long period of time in order to suppress the rise in blood sugar levels, and the strong bitter taste of gymnema is a major hindrance to its application as a functional food or medicine.
[課題を解決するための手段]
本発明は上記の問題点をカプセル化技術の利用により解
決したもので、本発明はギムネマと天然水溶性高分子を
含有し、この組成物にレシチン誘導体を配合した天然油
分中に乳化してなるカプセル内容物とした機能食品を提
供することにある。[Means for Solving the Problems] The present invention solves the above-mentioned problems by using encapsulation technology. To provide a functional food whose capsule contents are emulsified in natural oil.
すなわち、本発明のギムネマはギムネマ シルベスタ(
Gymnema 5ylvestre R、Br 、
H以下GSと省略)でガガイモ科に属するつる性植物
でインド、東南アジア等の熱帯、亜熱帯に自生する植物
である。That is, the gymnema of the present invention is Gymnema sylvestre (
Gymnema 5ylvestre R, Br,
It is a climbing plant belonging to the Asclepiadaceae family (abbreviated as GS below) and is a plant that grows naturally in tropical and subtropical regions such as India and Southeast Asia.
本発明のGSとしては、乾燥したGSS集葉微粉砕した
物(例えば150〜250メンシユ〉や、GSS集葉生
また乾燥した物を水、又はアルコール/水系溶媒等で冷
浸ないし温浸しGS抽出液を得ることが出来る。The GS of the present invention includes dried GSS leaves that have been finely ground (for example, 150 to 250 grains), or fresh or dried GSS leaves that are cold-soaked or hot-soaked in water or an alcohol/water-based solvent, etc., for GS extraction. liquid can be obtained.
このGS抽出液は目的によって濃縮1分離あるいは$!
製した物であっても良い。またGS成分を分離した物を
化学的(例えば酸・アルカリ処理)あるいは酵素的処理
等によってGSを改質した物を使用することが出来る。This GS extract can be concentrated by 1 separation or $! depending on the purpose.
It may be a manufactured product. Furthermore, it is possible to use a product obtained by separating the GS component and modifying the GS by chemically (for example, acid/alkali treatment) or enzymatic treatment.
GSの使用量は、製造の意図により任意に定められる。The amount of GS used is arbitrarily determined depending on the manufacturing intention.
GSの微粉末を使う場合には、2〜70重量%が好まし
く20〜40重量%がさらに好ましい。また、GSの抽
出エキス等で添加する場合GSの有効成分であるギムネ
ム酸誘導体として0゜01〜2.0重量%含有が好まし
く、0.05〜1.0M量%がさらに好ましい。When using fine GS powder, the content is preferably 2 to 70% by weight, more preferably 20 to 40% by weight. In addition, when adding as an extract of GS, the content of the gymnemic acid derivative, which is an active ingredient of GS, is preferably 0.01 to 2.0% by weight, more preferably 0.05 to 1.0M%.
本発明の天然水溶性高分子としては糊料、ゲル化性、増
粘安定性、賦形性等の作用を示す物であれば特に限定さ
れない。The natural water-soluble polymer used in the present invention is not particularly limited as long as it exhibits functions such as thickening, gelling properties, thickening stability, and shaping properties.
例えば海藻粘質物としては寒天、カラギーナン、ファー
セルラン、アルギン酸等を挙げることが出来る、植物性
水溶性高分子としてはアラビアガム、グアガム、ローカ
ストビーンガム、タマリンドウ、ペクチン、コンニャク
マンナン、デンプン、デキストリン等を挙げることが出
来る。微生物生産水溶性高分子としては、プルラン、キ
サンタガム等を挙げることが出来る。For example, seaweed mucilages include agar, carrageenan, furcellulan, alginic acid, etc., and vegetable water-soluble polymers include gum arabic, guar gum, locust bean gum, tamarind, pectin, konjac mannan, starch, and dextrin. etc. can be mentioned. Examples of water-soluble polymers produced by microorganisms include pullulan and xanta gum.
その他動植物性タンパク質水溶性高分子としては、カゼ
イン、ゼラチン、大豆タンパク質、小麦グルテン等を挙
げることが出来る。これらの天然水溶性高分子は、ギム
ネマ組成物を天然油成分の分離ないし油成分同士の凝集
を妨げ乳化安定させる組合せが特に好ましい。その使用
料はGSの配合形態によって決められるGS成分と天然
水溶性高分子の組成物粘度が30℃で1000センチポ
イズ以上に成る様な量である。粘度1000センチポイ
ズ以下であると、カプセル内容物の安定性が低下し、カ
プセルを熔解したり変形するため好ましくない。Other animal and vegetable protein water-soluble polymers include casein, gelatin, soybean protein, and wheat gluten. It is particularly preferred that these natural water-soluble polymers are used in combination to stabilize the emulsion of the gymnema composition by preventing separation of natural oil components or aggregation of oil components. The amount used is such that the viscosity of the composition of the GS component and the natural water-soluble polymer determined by the formulation of the GS becomes 1000 centipoise or more at 30°C. If the viscosity is less than 1000 centipoise, the stability of the capsule contents decreases, and the capsule may melt or deform, which is not preferable.
該天然水溶性高分子に有機酸及びまたは、その塩を配合
することはカプセル内容物を安定化させるために添加さ
れる。その例としてはリンゴ酸、酒石酸、フマル酸、食
用酸やかんきつ系果汁等はその塩も挙げることが出来る
。また無機酸またはその塩(例えばリン酸、リン酸三ナ
トリウム等)も使用することが出来るが機能性食品であ
るためあまり好ましくない。An organic acid and/or a salt thereof is added to the natural water-soluble polymer in order to stabilize the contents of the capsule. Examples include malic acid, tartaric acid, fumaric acid, food acids, citrus fruit juices, and their salts. Inorganic acids or their salts (for example, phosphoric acid, trisodium phosphate, etc.) can also be used, but they are not so preferred because they are functional foods.
有機酸またはその塩の使用量は、カプセル内容物を安定
化させる量であり特に限定されない。好ましくはカプセ
ル内容物のPHが1.7〜3.6になる様な量である。The amount of the organic acid or its salt to be used is an amount that stabilizes the contents of the capsule and is not particularly limited. Preferably, the amount is such that the pH of the capsule contents is 1.7 to 3.6.
本発明の天然油としては、カプセル内容物中の水分がカ
プセル皮膜剤に移行しないように油相を形成するために
添加される。また天然油が持っ薬理、栄養効果を併用す
るために配合する。The natural oil of the present invention is added to form an oil phase so that water in the capsule contents does not migrate to the capsule coating agent. It is also blended to combine the medicinal and nutritional effects of natural oils.
天然油としては、動物油、植物油、動植物由来の油であ
り、植物油としては、紅花油、サフラワー油、月見草油
、ヤシ油、大豆油、オリーブ油、ホホバ油、アボガド油
、小麦胚芽油等であり、動物油としては、スクリーン、
スツポン油、ミンク油、ウナギ油等であり、動植物油由
来の油としては、リルン酸、リノール酸、エイコペンク
エン酸、ドコサヘキサエン酸等を挙げることが出来る。Natural oils include animal oils, vegetable oils, and oils derived from animals and plants, and vegetable oils include safflower oil, safflower oil, evening primrose oil, coconut oil, soybean oil, olive oil, jojoba oil, avocado oil, and wheat germ oil. , as animal oil, screen;
Examples of oils derived from animal and vegetable oils include stingray oil, mink oil, and eel oil.
好ましくは、低温で結晶が析出しない様な天然油であり
単独ないし数種類配合することも出来る。Preferably, it is a natural oil that does not precipitate crystals at low temperatures, and can be used alone or in combination.
天然油の使用量は、カプセル内容物の重量に対して2%
以上で好ましくは30〜60重量%である。添加量が2
M量%以下では製品の安定性が良くなく、水分の移動が
起こりやすくカプセル皮膜剤を熔解したり変形するため
好ましくない。The amount of natural oil used is 2% based on the weight of the capsule contents.
The above amount is preferably 30 to 60% by weight. Addition amount is 2
If the amount of M is less than %, the stability of the product is not good, moisture movement is likely to occur, and the capsule coating agent is undesirably melted or deformed.
本発明のレシチン誘導体としては、大豆、卵黄、小麦胚
芽、ウナギ、動物m器等に含有している物から抽出、分
離されたものである。また抽出、分離ならびに精製等さ
れたレシチンを化学的修飾(例えば酸、アルカリ処理)
酵素的処理等に改質を行った物も使用することが出来る
。The lecithin derivatives of the present invention are extracted and separated from substances contained in soybeans, egg yolks, wheat germs, eels, animal organs, etc. Additionally, extracted, separated, and purified lecithin is chemically modified (e.g., acid or alkali treatment).
Products modified by enzymatic treatment etc. can also be used.
レシチン誘導体の作用は、GS天然水溶性高分子の組成
物と天然油成分のバランスを変え、水に対する分散性を
向上させ、またカプセル内容物の物性を改良することが
出来る。The action of the lecithin derivative can change the balance between the composition of the GS natural water-soluble polymer and the natural oil component, improve the dispersibility in water, and improve the physical properties of the capsule contents.
また、レシチン誘導体の構$、戒分であるコリン質の効
果により脂肪肝を予防し、更に血中コレステロール低下
作用も併有している。In addition, due to the composition of lecithin derivatives and the effect of choline, which is a precept, it prevents fatty liver and also has the effect of lowering blood cholesterol.
レシチン誘導体の使用量はカプセル内容重量に対し1〜
30%であり、好ましくは3〜20%がさらに好ましい
。The amount of lecithin derivative used is 1 to 10% of the weight of the capsule contents.
30%, preferably 3 to 20% is more preferred.
1重量%以下であると、上記の効果が期待しにくく、3
0重量%であると、レシチン誘導体の風味が強く出て、
不快感を与え、製造コストも上昇する。If it is less than 1% by weight, it is difficult to expect the above effects, and 3
When it is 0% by weight, the flavor of the lecithin derivative comes out strongly,
This causes discomfort and increases manufacturing costs.
天然油とGS、天然水溶性高分子の組成物を均一混合す
るのは通常の方法が行われる。例えば、デイスパー混合
攪拌機、ホモ主キサ−、コロイドミル等を使用すること
が出来る。A conventional method is used to uniformly mix the natural oil, GS, and natural water-soluble polymer composition. For example, a disper mixer, a homogen mixer, a colloid mill, etc. can be used.
カプセル内容物において本発明の目的を損なわない範囲
で他の配合剤、例えば栄養補強にビタえン類、ミネラル
類、アミノ酸類等、着色剤や酸化防止剤等を添加するの
は任意である。It is optional to add other compounding agents to the capsule contents, such as vitamins, minerals, amino acids, etc. for nutritional reinforcement, coloring agents, antioxidants, etc., within a range that does not impair the purpose of the present invention.
次に常法に従って、主機のカプセル内容物を充填するこ
とが出来る。例えば、浸漬法、打ち抜き法、滴下法等の
充填法で製造することが出来る。The capsule contents of the main machine can then be filled according to conventional methods. For example, it can be manufactured by a filling method such as a dipping method, a punching method, or a dropping method.
〈実施例〉 以下実施例によって本発明を更にくわしく説明する。<Example> The present invention will be explained in more detail below with reference to Examples.
本発明は、これ等の実施例によって限定されるものでは
ない。The present invention is not limited to these examples.
実施例 l
ギムネマ シルベスタ(GS)微粉末200メツシユパ
ス50B、精製水50部、アラビアガム1部、プルラン
4部、デキストリン10部、及びクエン酸2.5部を分
散させ、60℃に加熱し分散液とする。Example 1 Gymnema sylvestre (GS) fine powder 200, meshupas 50B, 50 parts of purified water, 1 part of gum arabic, 4 parts of pullulan, 10 parts of dextrin, and 2.5 parts of citric acid were dispersed and heated to 60°C to form a dispersion liquid. shall be.
一方月見草油50部60℃に加熱し大豆レシチンを7.
5部均一に乳化液とする。この乳化液中に調整した分散
液を均一になるまでコロイドミルで攪拌し、カプセル内
容物を得た。Meanwhile, heat 50 parts of evening primrose oil to 60°C and add soybean lecithin to 7.
Mix 5 parts uniformly to make an emulsion. The dispersion prepared in this emulsion was stirred with a colloid mill until it became homogeneous to obtain capsule contents.
一方カプセル皮膜剤の調整として、精製ゼラチン80部
、ソルビトール25部、精製水60部を吸水膨潤させ8
0″Cに加熱し、均一にf4解させ、カプセル皮膜剤を
得る。On the other hand, to prepare a capsule coating agent, 80 parts of purified gelatin, 25 parts of sorbitol, and 60 parts of purified water were swollen by water absorption.
Heat to 0''C to uniformly decompose F4 to obtain a capsule coating agent.
カプセル皮膜剤に先に調整したカプセル内容物を用いて
ロータリー式打ち抜き法により充填成形し、本発明によ
る機能食品を製造した。A functional food according to the present invention was produced by filling and molding the capsule coating agent with the previously prepared capsule contents using a rotary punching method.
このカプセルの内容物は400trgでカプセル皮膜剤
は120■であった。The content of this capsule was 400 trg and the capsule coating agent was 120 tg.
実施例 2
ギムネマ シルベスタ100gに精製水500meを加
え24時間加熱抽出し濾過後、ロータリーエバポレータ
ーで濃縮を行いGSエキス180gを得た。Example 2 500g of purified water was added to 100g of Gymnema sylvestre, extracted by heating for 24 hours, filtered, and concentrated using a rotary evaporator to obtain 180g of GS extract.
このGSエキス30部、精製水30部、アラビアガム4
部デキストリン11部及びリンゴ酸2.3部を加え分散
させ、60℃に加熱し分散液とする。30 parts of this GS extract, 30 parts of purified water, 4 parts of gum arabic
11 parts of dextrin and 2.3 parts of malic acid were added and dispersed, and heated to 60°C to form a dispersion.
以下実施例1と同様にして、本発明のi脂性食品を製造
した。The i-fat food of the present invention was produced in the same manner as in Example 1.
実施例 3
実施例2で用いた月見草油を小麦胚芽油40部、γ−リ
ノール酸10部、天然ビタミンE1.0部に変えた以外
同様にして本発明の機能性食品を製造した。Example 3 A functional food of the present invention was produced in the same manner as in Example 2, except that the evening primrose oil used in Example 2 was replaced with 40 parts of wheat germ oil, 10 parts of γ-linoleic acid, and 1.0 part of natural vitamin E.
実施例 4
実施例3で用いた大豆レシチンを卵黄レシチン6、0部
に変えた以外同様にして本発明の機能性食品を製造した
。Example 4 A functional food of the present invention was produced in the same manner as in Example 3, except that 6.0 parts of egg yolk lecithin was used instead of soybean lecithin.
[発明の効果]
本発明に係るギムネマ シルベスタをカプセル化するこ
とで苦味成分や風味を抑制することで、不快感がなく長
期間持続して、服用可能にした機能性食品を特徴する[Effects of the Invention] The functional food of the present invention is characterized by suppressing bitterness components and flavor by encapsulating Gymnema sylvestre, thereby making it possible to take it for a long period of time without causing discomfort.
Claims (1)
シチン誘導体を配合して成る組成物をカプセル内に充填
した機能性食品。 2)該天然水溶性高分子に有機酸及びまたはその塩を含
有してなる請求項1記載の機能性食品。[Scope of Claims] 1) A functional food in which a capsule is filled with a composition comprising a mixture of gymnema and a natural water-soluble polymer, combined with a natural oil and a lecithin derivative. 2) The functional food according to claim 1, wherein the natural water-soluble polymer contains an organic acid and/or a salt thereof.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1187906A JPH03130051A (en) | 1989-07-19 | 1989-07-19 | Functional food |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1187906A JPH03130051A (en) | 1989-07-19 | 1989-07-19 | Functional food |
Publications (1)
Publication Number | Publication Date |
---|---|
JPH03130051A true JPH03130051A (en) | 1991-06-03 |
Family
ID=16214273
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP1187906A Pending JPH03130051A (en) | 1989-07-19 | 1989-07-19 | Functional food |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPH03130051A (en) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH06343421A (en) * | 1993-06-08 | 1994-12-20 | Yasutake Hichi | High fat food having antiobestic function |
EP0826372A3 (en) * | 1996-09-03 | 1998-07-08 | Emil Flachsmann AG | Process for the preparation of a stable, homogeneous, from secondary reaction products free or nearly free extract |
US6887307B1 (en) | 1999-07-22 | 2005-05-03 | Warner-Lambert Company, Llc | Pullulan film compositions |
JP2006519867A (en) * | 2003-03-04 | 2006-08-31 | アユールベデイツク−ライフ・インターナシヨナル・エルエルシー | Therapeutic composition |
JP4787361B2 (en) * | 2007-08-07 | 2011-10-05 | 富士通株式会社 | Portable device |
JP2012051945A (en) * | 2003-11-21 | 2012-03-15 | Wakunaga Pharmaceut Co Ltd | Capsule, method for manufacturing the same, and capsule wall |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5588666A (en) * | 1978-12-27 | 1980-07-04 | Ueno Seiyaku Oyo Kenkyusho:Kk | Coated organic acid preparation having improved quality, and its preparation |
JPS6438026A (en) * | 1987-07-31 | 1989-02-08 | Nitto Denko Corp | Glucide absorption inhibitor |
-
1989
- 1989-07-19 JP JP1187906A patent/JPH03130051A/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5588666A (en) * | 1978-12-27 | 1980-07-04 | Ueno Seiyaku Oyo Kenkyusho:Kk | Coated organic acid preparation having improved quality, and its preparation |
JPS6438026A (en) * | 1987-07-31 | 1989-02-08 | Nitto Denko Corp | Glucide absorption inhibitor |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH06343421A (en) * | 1993-06-08 | 1994-12-20 | Yasutake Hichi | High fat food having antiobestic function |
EP0826372A3 (en) * | 1996-09-03 | 1998-07-08 | Emil Flachsmann AG | Process for the preparation of a stable, homogeneous, from secondary reaction products free or nearly free extract |
US6887307B1 (en) | 1999-07-22 | 2005-05-03 | Warner-Lambert Company, Llc | Pullulan film compositions |
US7267718B2 (en) | 1999-07-22 | 2007-09-11 | Warner-Lambert Company, Llc | Pullulan film compositions |
JP2006519867A (en) * | 2003-03-04 | 2006-08-31 | アユールベデイツク−ライフ・インターナシヨナル・エルエルシー | Therapeutic composition |
JP2012051945A (en) * | 2003-11-21 | 2012-03-15 | Wakunaga Pharmaceut Co Ltd | Capsule, method for manufacturing the same, and capsule wall |
JP4787361B2 (en) * | 2007-08-07 | 2011-10-05 | 富士通株式会社 | Portable device |
US8188684B2 (en) * | 2007-08-07 | 2012-05-29 | Fujitsu Limited | Portable device, recording medium storing light emission control program and light emission control method thereof |
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