JPH0310602B2 - - Google Patents

Description

[Detailed description of the invention]

INDUSTRIAL APPLICATION FIELD The present invention relates to a dental cement composition that is effective and has features in dental treatment in that it is less irritating, particularly irritating odor, has high strength and excellent removability. Conventional technology A variety of dental cements are in practical use, and one of them is agent A, which is zinc white (ZnO).
The BB agent is a combination preparation consisting of eugenol (also called eugenol; it is the main component of clove oil, so it is sometimes referred to as clove oil itself), and agents A and B are mixed together before use. Eugenol cement, which is used in the form of a paste, has a long history and is still indispensable clinically today. The clinical uses of this cement include gingival bandages, pulp capping, temporary sealing, root canal filling, denture lining, and impressions, but the cement contains eugenol and has a characteristic odor and temporary Research is being conducted to replace Eugenol with other substances because it has a pungent taste, and because it is a natural product, there are fluctuations in price, quality, and supply and demand. Organic acids are known as such substitutes, and products using orthoethoxybenzoic acid (EBA) as an agent (EBA cement: Evacement:
OPOTOW (USA) is in practical use.
The EBA cement contains powder containing zinc oxide and EBA
This is a so-called powder-liquid dental cement that uses a liquid agent containing EBA and Eugenol as a hardening agent. Eugenol is prescribed in the EBA cement because if EBA is used alone as a hardening agent, the hardening reaction proceeds extremely rapidly, so it is to suppress it, and although it is not practical, it is suitable as a reaction retarder. Since I don't have any, dilute EBA with eugenol,
The curing reaction is delayed without compromising operability. However, as mentioned above, the odor and taste peculiar to Eugenol remain, and the strength of the hardened cement increases due to the joint action of Eugenol and EBA, so it does not meet the purpose of temporary sealing, which will be described later. The composition of the present invention is a dental cement that does not require the combined use of eugenol, and since it does not contain eugenol, it is necessary to devise a formulation for the base agent and curing agent. That is, in the present invention, in particular, in addition to EBA, organic unsaturated and/or saturated fatty acids, as well as polyhydric alcohols and/or polyalkylene glycols are blended into the curing agent, thereby creating a temporary curing agent that does not contain any eugenol. A cement composition has been successfully produced which exhibits suitable strength for sealing purposes. The cement according to the invention is primarily used for temporary sealing purposes. Temporary sealing is a temporary seal (several hours to a week) that seals the hole (socket) in the tooth that has been cut for treatment, sealing it off for a period of time (several hours to a week) to prevent saliva, bacteria, and This method is used to prevent food from coming into direct contact with the treated tooth structure. The material used for this purpose is called a temporary sealant, and various materials are used, but one of the materials that satisfies most of the requirements for this material is zinc oxide eugenol cement. List a few of these conditions. (a) Sealability (ability to seal the affected area by adhering closely to the tooth structure): The sealability depends not only on the adhesion of the cement to the tooth structure, but also on the hardness of the hardened cement itself (fracture resistance: Strength: 70-200
Kg/cm ² ), and as long as the removability described below is good, the harder the seal, the better the sealing performance will be. (b) Strength: As mentioned above, it must withstand occlusal pressure during eating. As long as the removability described below is ensured, the harder the better. (c) Removability: Temporary sealants must be removed for treatment at the next visit. During removal, a metal device (called an excavator) with an L-shaped tip is usually heated to red with a flame, inserted into the cement when it is hot, wait until it cools, and remove the excavator from the cement. When the cement is removed, it is entangled in the excavator and removed as a lump. Necessary conditions include that the excavator can be inserted easily and that no smoke is emitted during insertion. As described above, the performance required of a temporary sealant is mutually contradictory; if the cement is not strong, it will not be able to withstand occlusal pressure, and conversely, if the cement is too strong, it will be difficult to remove. Therefore, in reality, zinc oxide eugenol cement is most widely used today as a temporary sealing agent that does not require much increase in strength and has a certain level of removability, and has good sealing properties. When the above cement is used as a temporary sealant, appropriate amounts of Agents A and B are kneaded during treatment to form a hard paste, which quickly hardens after being applied to the oral cavity and reduces occlusal pressure. It must have the strength to withstand. After application, it must have the ability to be easily removed as a lump by poking it with an excavator heated with a flame, if necessary. Manufacturers are making efforts to provide this performance to the cement, but there are limits to this, and commercially available products have both advantages and disadvantages. The applicant is JP-A-60-181004
In No. 1, a composition that does not use eugenol in agent B does not exhibit the characteristic irritating odor and coloring derived from eugenol, and can be suitably used for clinical purposes in the same way as cement compositions that use eugenol. This is disclosed. However, as mentioned above, the temporary sealant should have better performance than the cement, that is, the performance as a temporary sealant. In particular, sealing properties that completely seal the application site, strength that can withstand occlusal pressure, and removability are required. Problems to be Solved by the Invention As a result of various studies on the above points, the present inventors decided not to use eugenol in agent B in order to reduce the irritating odor caused by eugenol. We succeeded in satisfying the requirements of sealability, strength to withstand occlusal pressure, and ease of removal. Means for Solving the Problems The present invention comprises (a) zinc oxide, (b) a water-insoluble oxide,
and (c) a part A containing rosin, (d) a curing agent selected from orthoethoxybenzoic acid or orthomethoxybenzoic acid, (e) a mixture of organic unsaturated fatty acids and organic saturated fatty acids, and (f) a polyhydric alcohol. This dental cement composition consists of a polyalkylene glycol or a B agent containing a mixture thereof, and the A agent and B agent are mixed together before use. Examples of the oxide include magnesium oxide and silicic acid. The organic unsaturated fatty acids used in the present invention include oleic acid, elaidic acid, erucic acid, and undecylenic acid corresponding to the general formula CnH _2o-1 COOH, linoleic acid corresponding to CnH _2o-3 COOH,
CnH _2o-5 is linolenic acid, etc., which corresponds to COOH,
Since these can be easily obtained on the market, they can be preferably used. However, n in the above formula means a numerical value of 1 to 22. Organic saturated fatty acids are acids corresponding to the general formula CnH _2o+1 COOH (n = 10 to 22), such as stearic acid, isostearic acid,
These are palmitic acid and myristic acid. Examples of polyhydric alcohols used in the invention are propylene glycol or glycerin, and examples of polyalkylene glycols are polyethylene glycol or polypropylene glycol. The aromatic carboxylic acid is benzoic acid having a methoxyl group and/or an ethoxyl group at the ortho position. These constitute the composition of B agent, which is a curing agent, and B
The content of organic unsaturated fatty acids in the agent is 5 to 50% by weight, and the content of organic saturated fatty acids is 5 to 50% by weight.
50% by weight, the content of polyhydric alcohol or polyalkylene glycol or a mixture thereof is 5-50% by weight, and the content of aromatic carboxylic acid is 20-80% by weight. Next, we will explain the case where this agent is used as a temporary sealant. The temporary sealant hardens in about 3 to 5 minutes after filling, and the hardened material is non-irritating, can withstand the bite of food, does not break or wear away, and adheres tightly to the tooth structure, leaving the cement intact until it is removed. The margin of the tooth and the gap between the teeth must be completely sealed (referred to as margin sealing) to completely prevent the invasion of bacteria in the oral cavity. The degree of adhesion of the cement composition or the strength of the cement after hardening are largely related to the edge sealing properties. Also, if the strength is too large (for example, 300Kg or 500Kg exceeding 200Kg)
This makes it difficult to remove it at a later date. However, according to the present invention, a temporary sealant that has high strength and is easy to remove has been developed. The following methods are used to measure sealability, strength, and removability. a Measurement of sealability: Fill a glass tube with an inner diameter of 4 mm and a length of 70 mm with dehydrated copper sulfate powder, seal one end with the test cement and the other end with silicone rubber, and then place it in hot water at 37°C for 7 days.
After soaking for a day, the degree of discoloration of copper sulfate in the glass tube is examined. b Measurement of cement strength (JIS T-6602): A cylindrical test piece with an outer diameter of 6 mm and a length of 12 mm was created using a mold, and after being immersed in hot water at 37°C for 24 hours, it was heated at a speed of 0.25 mm per minute. The test piece is compressed and the compressive strength is measured by a conventional method. c. Measurement of removability: Fill a glass tube with an inner diameter of 4 mm and a length of 30 mm with the test cement, and after hardening, poke it with an excavator heated with a flame to check how easily the hardened material can be removed. The above A test measures the sealing properties, and if the copper sulfate changes color, it means that moisture has entered from the interface between the cement and the tooth structure. judge. Furthermore, it is said that the compressive strength of cement for temporary sealing according to the b test is required to be at least 70 to 200 kg/cm ² . Furthermore, since there are individual differences in the evaluation of removability using the c test, evaluations are performed on at least five or more subjects. Of course, the dental temporary sealing cement composition used in the present invention passed the A test, and the strength was approximately
It weighs 300Kg//cm ² and is also easy to remove.
If the temporary sealant is too strong, it will be difficult to remove it at a later date. However, the seemingly contradictory properties of high strength and easy removal are required in clinical practice. The present invention has succeeded in imparting this property to the cement. Example 1 Agent A was produced by mixing 85 g of JP zinc white and 15 g of JP rosin and grinding the mixture into 150 meshes. Part B was produced by uniformly mixing 5 g of linoleic acid (first class reagent), 50 g of isostearic acid (first class reagent), 5 g of propylene glycol (special grade reagent), and 40 g of O-ethoxybenzoic acid (first class reagent). Example 2 Agent A was produced by mixing 80 g of JP zinc white, 15 g of JP rosin, and 5 g of JP magnesium oxide and grinding the mixture into 150 meshes. Part B is 34g of linoleic acid (first class reagent), 5g of isostearic acid (first class reagent), and 40g of propylene glycol (special class reagent).
It was produced by mixing and further dissolving 20 g of o-methoxybenzoic acid and mixing the whole mixture evenly. Example 3 Agent A was produced by mixing 80 g of JP zinc white, 15 g of JP rosin, and 5 g of silicic acid (first class reagent) and grinding the mixture into 150 meshes. Part B is linoleic acid (first class reagent) 5g, isostearic acid (first class reagent) 15g, polyethylene glycol (Japanese Pharmacopoeia reagent)
10g of o-ethoxybenzoic acid and 70g of o-ethoxybenzoic acid were mixed evenly throughout. Table 1 shows the curing time, sealing properties, strength values, and removability evaluations measured for the compositions obtained in Examples 1, 2, and 3 above. Table 2 shows the evaluation results and a comparison with the conventional technology.

【table】

【table】

[Table] The cement based on the composition of the present invention produced as in the above examples passed the sealing property test, showed a strength of 300 kg/cm ² or more, and was easy to remove. It has high utility value as an excellent temporary sealant that improves on conventional technology. The cement composition of the present invention in Example 2 (hereinafter referred to as Cement Composition 1) was compared with the cement composition described in Example 3 of JP-A-60-181004 (hereinafter referred to as Cement Composition 2). Cement composition B was manufactured according to the method described in the above document. Cement compositions 1 and 2 were mixed in the following proportions in a conventional manner to produce mixed mud, which was poured into stainless steel molds to obtain cylindrical hardened cement products A and 6 mm in diameter and 12 mm in height.

[Table] Cement composition 2 3: 1

Claims (1)

[Claims] 1 (a) zinc oxide, (b) a water-insoluble oxide, and (c)
A agent containing rosin and (d) 20 selected from orthoethoxybenzoic acid or orthomethoxybenzoic acid.
~80% by weight of curing agent, (e) 5-50% by weight of a mixture of organic unsaturated fatty acids and organic saturated fatty acids, and (f) 5
A dental cement composition comprising a B agent containing ~50% by weight of polyhydric alcohol, polyalkylene glycol, or a mixture thereof, and which is used by mixing A and B agents at the time of use. 2. The composition according to claim 1, wherein the agent A is in powder form and the agent B is in liquid form. 3 Organic unsaturated fatty acids have 10 to 22 carbon atoms and their general formulas are C _o H _2o-1 COOH, C _o H _2o-3 COOH, _Co
The composition according to claim 1, which corresponds to any one of H _2o-5 COOH. 4. The composition according to claim 1, wherein the organic saturated fatty acid has the general formula C _o H _2o+1 COOH (where n represents an integer of 10 to 22). 5. The composition according to claim 1, wherein the polyhydric alcohol is propylene glycol, glycerin, or a mixture thereof. 6. The composition according to claim 1, wherein the polyalkylene glycol is polyethylene glycol, polypropylene glycol, or a mixture thereof. 7. The composition according to claim 1, wherein the oxide is magnesium oxide or silicic acid.