JPH0283315A - Solubilized substance of tocopherol - Google Patents
Solubilized substance of tocopherolInfo
- Publication number
- JPH0283315A JPH0283315A JP63237271A JP23727188A JPH0283315A JP H0283315 A JPH0283315 A JP H0283315A JP 63237271 A JP63237271 A JP 63237271A JP 23727188 A JP23727188 A JP 23727188A JP H0283315 A JPH0283315 A JP H0283315A
- Authority
- JP
- Japan
- Prior art keywords
- tocopherol
- weight
- solubilized
- water
- ethanol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229930003799 tocopherol Natural products 0.000 title claims abstract description 33
- 239000011732 tocopherol Substances 0.000 title claims abstract description 33
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 title claims abstract description 30
- 229960001295 tocopherol Drugs 0.000 title claims abstract description 30
- 235000010384 tocopherol Nutrition 0.000 title claims abstract description 30
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 title claims abstract description 30
- 239000000126 substance Substances 0.000 title abstract description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 20
- 239000003995 emulsifying agent Substances 0.000 claims abstract description 11
- 238000002156 mixing Methods 0.000 claims abstract description 8
- 235000000346 sugar Nutrition 0.000 claims description 6
- 150000008163 sugars Chemical class 0.000 claims description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 12
- -1 sucrose Chemical class 0.000 abstract description 8
- 150000001720 carbohydrates Chemical class 0.000 abstract description 7
- 235000013305 food Nutrition 0.000 abstract description 7
- 239000003963 antioxidant agent Substances 0.000 abstract description 5
- 230000003078 antioxidant effect Effects 0.000 abstract description 5
- 229930006000 Sucrose Natural products 0.000 abstract description 3
- 239000000654 additive Substances 0.000 abstract description 3
- 150000007524 organic acids Chemical class 0.000 abstract description 3
- 230000003381 solubilizing effect Effects 0.000 abstract description 3
- 239000005720 sucrose Substances 0.000 abstract description 3
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 abstract description 2
- 150000001413 amino acids Chemical class 0.000 abstract description 2
- LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000005063 solubilization Methods 0.000 description 7
- 230000007928 solubilization Effects 0.000 description 7
- 235000014113 dietary fatty acids Nutrition 0.000 description 6
- 229930195729 fatty acid Natural products 0.000 description 6
- 239000000194 fatty acid Substances 0.000 description 6
- 235000006708 antioxidants Nutrition 0.000 description 4
- 238000002360 preparation method Methods 0.000 description 4
- 230000000052 comparative effect Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 239000000839 emulsion Substances 0.000 description 3
- 235000019149 tocopherols Nutrition 0.000 description 3
- QUEDXNHFTDJVIY-UHFFFAOYSA-N γ-tocopherol Chemical class OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1 QUEDXNHFTDJVIY-UHFFFAOYSA-N 0.000 description 3
- IMQLKJBTEOYOSI-UHFFFAOYSA-N Diphosphoinositol tetrakisphosphate Chemical compound OP(O)(=O)OC1C(OP(O)(O)=O)C(OP(O)(O)=O)C(OP(O)(O)=O)C(OP(O)(O)=O)C1OP(O)(O)=O IMQLKJBTEOYOSI-UHFFFAOYSA-N 0.000 description 2
- 239000012736 aqueous medium Substances 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- DNIAPMSPPWPWGF-UHFFFAOYSA-N monopropylene glycol Natural products CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 2
- 150000002772 monosaccharides Chemical class 0.000 description 2
- 239000003921 oil Substances 0.000 description 2
- 230000000704 physical effect Effects 0.000 description 2
- 150000004043 trisaccharides Chemical class 0.000 description 2
- PIGTXFOGKFOFTO-FVFWYJKVSA-N (2S,3S,4S,5R,6R)-6-[[(3S,4S,4aR,6aR,6bS,8R,8aR,12aS,14aR,14bR)-8a-carboxy-4-formyl-8-hydroxy-4,6a,6b,11,11,14b-hexamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound O([C@H]1CC[C@]2(C)[C@H]3CC=C4[C@@]([C@@]3(CC[C@H]2[C@@]1(C=O)C)C)(C)C[C@@H](O)[C@]1(CCC(C[C@H]14)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O PIGTXFOGKFOFTO-FVFWYJKVSA-N 0.000 description 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerol Natural products OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000004945 emulsification Methods 0.000 description 1
- 239000003889 eye drop Substances 0.000 description 1
- 239000003925 fat Substances 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 229920001206 natural gum Polymers 0.000 description 1
- 229920001542 oligosaccharide Polymers 0.000 description 1
- 150000002482 oligosaccharides Chemical class 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 229930182490 saponin Natural products 0.000 description 1
- 150000007949 saponins Chemical class 0.000 description 1
- 235000017709 saponins Nutrition 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 150000005846 sugar alcohols Chemical class 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
Abstract
Description
【発明の詳細な説明】
〔産業上の利用分野〕
本発明はトコフェロールを水溶性媒体に可溶化した透明
で安定かつ低粘度のトコフェロール可溶化物に関し、特
に食品に適するトコフェロール可溶化物に関するもので
ある。[Detailed Description of the Invention] [Industrial Application Field] The present invention relates to a transparent, stable and low-viscosity tocopherol solubilized product in which tocopherol is solubilized in an aqueous medium, and in particular to a tocopherol solubilized product suitable for foods. be.
トコフェロールは安全性、物性、効果の点で優れた抗酸
化物質であり、特に食品用抗酸化剤として最も広く用い
られている。Tocopherol is an antioxidant substance with excellent safety, physical properties, and effectiveness, and is most widely used as an antioxidant for foods.
ところが、トコフェロールは油溶性であるため、多水分
系の対象物に添加するためには、Ｏ／Ｗ（水中油）型に
乳化する必要がある。However, since tocopherol is oil-soluble, it is necessary to emulsify it into an O/W (oil-in-water) type in order to add it to a polyhydric object.
トコフェロールのＯ／Ｗ型乳化について特開昭６２−１
０６０１８号公報には、トコフェロールに脂肪酸エステ
ルを含有させた点眼剤等の水性製剤が開示されている。On O/W type emulsification of tocopherol JP-A-62-1
Publication No. 06018 discloses an aqueous preparation such as an eye drop containing tocopherol and a fatty acid ester.
また特開昭６２−１１１６７６号公報には、トコフェロ
ールとフィチン）′ｄ！とを含有し、天然ガム質を乳化
安定剤に用いた○／Ｗ型の乳液状の酸化防止剤が開示さ
れている。Furthermore, JP-A-62-111676 discloses tocopherol and phytin)'d! A ○/W type emulsion-like antioxidant containing the following and using a natural gum substance as an emulsion stabilizer is disclosed.
ところが、上記従来の技術には、流動性などの物性が不
適当であったり、乳化安定性が劣るなどの問題点がある
。However, the above-mentioned conventional techniques have problems such as inadequate physical properties such as fluidity and poor emulsion stability.
本発明の目的は、上記のような従来品の問題点を解決し
、透明で安定かつ低粘度の可溶化物で。The purpose of the present invention is to solve the problems of conventional products as described above, and to provide a transparent, stable, and low-viscosity solubilized product.
水への分散性に優れたトコフェロール可溶化物を提供す
ることである。An object of the present invention is to provide a tocopherol solubilized product having excellent dispersibility in water.
本発明は、トコフェロール１〜５０重量％、糖類１〜９
０重量％、乳化剤０．１〜３０重量％およびエタノール
１〜１０重量％を混合して可溶化したことを特徴とする
トコフェロール可溶化物である。The present invention contains 1 to 50% by weight of tocopherol, 1 to 9 saccharides,
The tocopherol solubilized product is characterized by being solubilized by mixing 0% by weight, 0.1 to 30% by weight of an emulsifier, and 1 to 10% by weight of ethanol.
本発明で用いるトコフェロールとしては、α、β、γ、
δのいずれの型のトコフェロールも使用できるが、天然
濃縮トコフェロール、およびこれを油脂で希釈したもの
が好ましい。これらのトコフェロールはいずれも市販さ
れており、市販品をそのままは独で、あるいは適宜組合
わせて用いることができる。トコフェロールの配合量と
しては、全体の１〜５０重景％、好ましくは５〜４０重
景％とするのが好ましい。］重量％未満では、トコフェ
ロールの効果を発揮することが難しくなり、５０重量％
を超えると可溶化が困難となる。The tocopherols used in the present invention include α, β, γ,
Although any form of tocopherol δ can be used, naturally concentrated tocopherols and those diluted with fats and oils are preferred. All of these tocopherols are commercially available, and commercially available products can be used alone or in appropriate combinations. The amount of tocopherol to be blended is preferably 1 to 50%, preferably 5 to 40% of the total. ] If the amount is less than 50% by weight, it will be difficult to exhibit the effect of tocopherol, and if the amount is less than 50% by weight,
If the amount exceeds 100%, solubilization becomes difficult.
本発明で用いる糖類としては、糖アルコール、ｔ）１糖
類、三糖類、三糖類、転化糖など、またはその水溶液を
それぞれ単独で、あるいは適宜組合わせて用いることが
できるが、シュークロースなどの単糖類またはオリゴ糖
類が好ましい。また、水溶液として用いる場合の糖類の
濃度は高い程良い。As the saccharide used in the present invention, sugar alcohols, monosaccharides, trisaccharides, trisaccharides, invert sugars, etc., or aqueous solutions thereof can be used alone or in appropriate combinations, but monosaccharides such as sucrose can be used. Sugars or oligosaccharides are preferred. Furthermore, when used as an aqueous solution, the higher the concentration of saccharides, the better.
糖類の配合量は１〜９０重散％、好ましくは１〜８０重
敗％とする。１重量％未満では可溶化ができず、９０重
量％を越えると逆に可溶化を抑制する。The blending amount of saccharides is 1 to 90% by weight, preferably 1 to 80% by weight. If it is less than 1% by weight, solubilization cannot be achieved, and if it exceeds 90% by weight, solubilization is inhibited.
本発明で用いる乳化剤としては、グリセリン脂肪酸エス
テル、ショ糖脂肪酸エステル、ソルビタン脂肪酸エステ
ル、プロピレングリコール脂肪酸エステル、ポリグリセ
リン脂肪酸エステル、サポニン類などがあるが、有機酸
モノグリセリド、キラヤサポニンが好ましい。乳化剤の
配合量は０．１〜３０重量％、好ましくは１〜２０重斌
％とする。Examples of emulsifiers used in the present invention include glycerin fatty acid esters, sucrose fatty acid esters, sorbitan fatty acid esters, propylene glycol fatty acid esters, polyglycerin fatty acid esters, saponins, and organic acid monoglycerides and Quillaja saponin are preferred. The blending amount of the emulsifier is 0.1 to 30% by weight, preferably 1 to 20% by weight.
０．１重量％未満では可溶化が困難であり、３０重に％
を超えるとコスト的に好ましくない。If it is less than 0.1% by weight, it is difficult to solubilize, and if it is less than 30% by weight,
Exceeding this is not desirable in terms of cost.
本発明で用いるエタノールとしては、天然および合成の
ものを利用できる。また、多少の水分を含んでいてもよ
いが、水分が１０重量％以下のエタノールが好ましい。Natural and synthetic ethanol can be used in the present invention. Further, although it may contain some water, ethanol with a water content of 10% by weight or less is preferable.
エタノールの配合量は１〜１０重量％、好ましくは２〜
８重量％とする。１重量％未満では可溶化効果が十分で
なく、１０重量％を超えると逆に可溶化を抑制する。The amount of ethanol blended is 1 to 10% by weight, preferably 2 to 10% by weight.
8% by weight. If it is less than 1% by weight, the solubilizing effect will not be sufficient, and if it exceeds 10% by weight, solubilization will be suppressed.
本発明のトコフェロール可溶化物には、可溶化を妨げな
い範囲で、有機酸、アミノ酸等の他の添加剤を配合する
ことができる。また本発明のトコフェロール可溶化物に
は水が含まれていても含まれていなくてもよく、いずれ
の場合も水に対する分散性が良好である。The tocopherol solubilized product of the present invention may contain other additives such as organic acids and amino acids within a range that does not interfere with solubilization. Further, the tocopherol solubilized product of the present invention may or may not contain water, and in either case, the tocopherol solubilized product has good dispersibility in water.
本発明のトコフェロール可溶化物は、上記各成分、なら
びに必要により配合される他の添加剤を混合して可溶化
したものである。調製法としては、トコフェロール中に
一部の乳化剤、その他の油溶性成分を溶解し、一方糖類
水溶液中、または糖類を５０〜７０℃に加温して粘度を
下げた液状物中に残りの乳化剤、エタノール、その他の
水溶性成分を溶解し、両者を１．Ｂ合すれば、可溶化が
起こる。混合には高速撹拌機、ホモジナイザーなどを用
いることができる。The tocopherol solubilized product of the present invention is obtained by mixing and solubilizing the above-mentioned components as well as other additives added as necessary. The preparation method involves dissolving a part of the emulsifier and other oil-soluble components in tocopherol, while dissolving the remaining emulsifier in an aqueous sugar solution or in a liquid obtained by heating the sugar to 50 to 70°C to lower its viscosity. , ethanol, and other water-soluble components, and both were dissolved in 1. If B is combined, solubilization occurs. A high-speed stirrer, a homogenizer, etc. can be used for mixing.
こうして得られたトコフェロール可溶化物は、白濁状の
乳化物とは異なり、トコフェロールが水溶性媒体中に安
定に可溶化して透明で低粘度の可溶化物となっており、
水に対する分散性が良好で、多水分系の食品等に任意の
割合で均一に混合することができる。このため食品、飼
料その他の用途に、抗酸化剤、ビタミン剤などとして用
いることができる。The tocopherol solubilized product thus obtained differs from a cloudy white emulsion in that tocopherol is stably solubilized in an aqueous medium, resulting in a transparent and low-viscosity solubilized product.
It has good dispersibility in water and can be uniformly mixed into high-moisture foods in any proportion. Therefore, it can be used as an antioxidant, vitamin agent, etc. in foods, feeds, and other uses.
本発明のトコフェロール可溶化物は糖類、乳化剤および
エタノールを用いることにより、非常に安定で、かつ低
粘度の状態に可溶化することができ、このため水への分
散性も優れており、食品などの風味を害することがない
などの効果がある。The tocopherol solubilized product of the present invention is extremely stable and can be solubilized to a low viscosity state by using sugars, emulsifiers, and ethanol. Therefore, it has excellent dispersibility in water, and can be used in foods, etc. It has the effect of not harming the flavor of the food.
〔実施例〕 次に実施例および比較例により本発明を説明する。〔Example〕 Next, the present invention will be explained with reference to Examples and Comparative Examples.
実施例１〜３、比較例１〜３
第１表に示す配合割合の原料を用いて、ホモジナイザー
により前記調製法に基づいて可溶化物を調製した。すな
わちトコフェロールに油溶性乳化剤を溶解し、一方糖類
に水溶性乳化剤、エタノールを溶解し、６０℃に加温後
両者をホモジナイザーで混合した。得られた可溶化物を
ガラス製メスシリンダーに入れて６０℃中で１０日間保
存し、可溶化状態および粘度を比較した。なお、粘度は
調製直後に２０℃にて、東京計器株式会社製Ｂ型粘度計
により相定した。結果を第１表に示した。Examples 1 to 3, Comparative Examples 1 to 3 Solubilized materials were prepared using a homogenizer based on the above-mentioned preparation method using raw materials in the proportions shown in Table 1. That is, an oil-soluble emulsifier was dissolved in tocopherol, and a water-soluble emulsifier and ethanol were dissolved in saccharide, and after heating to 60° C., both were mixed using a homogenizer. The obtained solubilized product was placed in a glass graduated cylinder and stored at 60° C. for 10 days, and the solubilized state and viscosity were compared. The viscosity was determined immediately after preparation at 20° C. using a B-type viscometer manufactured by Tokyo Keiki Co., Ltd. The results are shown in Table 1.
第１表の可溶化状態の観察結果および粘度のｉｌｌ！１
定結果から明らかなように１本発明により、トコフェロ
ールは完全に可溶化でき、また粘度が低いため、流動性
が僅れていることがわかる。Observation results of solubilization state and viscosity ill! in Table 1! 1
As is clear from the results, according to the present invention, tocopherol can be completely solubilized, and since the viscosity is low, the fluidity is low.
また実施例１〜３の可溶化物を１重斌％濃度で水に溶解
し、室温で１０日間保存したが、オイルオフなどの異常
は認められなかった。ところが、比較例１〜３で同じ試
験を行ったところ、オイルオフを起こし、油滴が浮上し
た。Further, the solubilized products of Examples 1 to 3 were dissolved in water at a concentration of 1% by weight and stored at room temperature for 10 days, but no abnormalities such as oil-off were observed. However, when the same test was conducted in Comparative Examples 1 to 3, oil-off occurred and oil droplets floated to the surface.
Claims (1)
量％、乳化剤０．１〜３０重量％およびエタノール１〜
１０重量％を混合して可溶化したことを特徴とするトコ
フェロール可溶化物。(1) 1 to 50% by weight of tocopherol, 1 to 90% by weight of sugars, 0.1 to 30% by weight of emulsifier, and 1 to 1% of ethanol
A tocopherol solubilized product characterized by being solubilized by mixing 10% by weight.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP63237271A JPH0283315A (en) | 1988-09-21 | 1988-09-21 | Solubilized substance of tocopherol |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP63237271A JPH0283315A (en) | 1988-09-21 | 1988-09-21 | Solubilized substance of tocopherol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH0283315A true JPH0283315A (en) | 1990-03-23 |
Family
ID=17012921
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP63237271A Pending JPH0283315A (en) | 1988-09-21 | 1988-09-21 | Solubilized substance of tocopherol |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH0283315A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006030850A1 (en) * | 2004-09-15 | 2006-03-23 | San-Ei Gen F.F.I., Inc. | Method of preparing solution of lipid-soluble ingredient |
-
1988
- 1988-09-21 JP JP63237271A patent/JPH0283315A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006030850A1 (en) * | 2004-09-15 | 2006-03-23 | San-Ei Gen F.F.I., Inc. | Method of preparing solution of lipid-soluble ingredient |
| JPWO2006030850A1 (en) * | 2004-09-15 | 2008-05-15 | 三栄源エフ・エフ・アイ株式会社 | Method for preparing solubilized product of fat-soluble component |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4379755A (en) | Gelatinizing agent composition, and gel and aqueous emulsion prepared therefrom | |
| JP4963958B2 (en) | Stable concentrated and diluted oil-in-water emulsions, processes for their preparation, and formulation processes using these emulsions | |
| JP2009505809A (en) | Emulsifier system, its emulsion and its use | |
| CN104661739A (en) | Lycopene-containing oil-in-water emulsion composition and production method therefor | |
| JPS62419A (en) | Water-soluble agent containing fat-soluble vitamin | |
| JPS60183032A (en) | Emulsified composition | |
| US6193986B1 (en) | Oily composition with increased stability and process for producing the same | |
| CN111643376A (en) | Nano-emulsion composition and application thereof | |
| JPH09501100A (en) | Water / oil emulsions and water / oil / water emulsions with high internal phase content | |
| JPS62250941A (en) | Preparation of emulsified or solubilized solution | |
| EP0084341A2 (en) | Emulsion-type composition for external use | |
| JPH0451853A (en) | Production of emulsion composition for food and drink | |
| CN104582827A (en) | Carotenoid-containing oil-in-water emulsion composition | |
| CN104114145A (en) | Oil-in-water emulsion composition | |
| US2143651A (en) | Food spread base | |
| JPS641173B2 (en) | ||
| JPH0283315A (en) | Solubilized substance of tocopherol | |
| JP4228435B2 (en) | Powdered oil and fat composition and method for producing the same | |
| JPS6160619A (en) | Dispersible powder | |
| JPH02102290A (en) | Solubilized tocopherol | |
| JPH0570494B2 (en) | ||
| JP2001069912A (en) | Thickener for oil and fat, and thickened oil and fat composition | |
| JPH09220464A (en) | Polyhydric alcohol gel-in-oil type emulsified composition and its production | |
| JP2546269B2 (en) | Tocopheroic acid emulsion | |
| JP2007275020A (en) | Oil-in-water type emulsified oil and fat composition containing fat-soluble vitamins |