JPH0241398A - Liquid, stabilized enzyme detergent composition - Google Patents
Liquid, stabilized enzyme detergent compositionInfo
- Publication number
- JPH0241398A JPH0241398A JP29479988A JP29479988A JPH0241398A JP H0241398 A JPH0241398 A JP H0241398A JP 29479988 A JP29479988 A JP 29479988A JP 29479988 A JP29479988 A JP 29479988A JP H0241398 A JPH0241398 A JP H0241398A
- Authority
- JP
- Japan
- Prior art keywords
- detergent composition
- composition according
- enzyme
- detergent
- amphoteric surfactant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102000004190 Enzymes Human genes 0.000 title claims abstract description 39
- 108090000790 Enzymes Proteins 0.000 title claims abstract description 39
- 239000000203 mixture Substances 0.000 title claims abstract description 34
- 239000003599 detergent Substances 0.000 title claims description 41
- 239000007788 liquid Substances 0.000 title claims description 10
- 229940088598 enzyme Drugs 0.000 claims abstract description 38
- 239000002280 amphoteric surfactant Substances 0.000 claims abstract description 13
- 108091005804 Peptidases Proteins 0.000 claims abstract description 12
- 239000004365 Protease Substances 0.000 claims abstract description 12
- 241000193830 Bacillus <bacterium> Species 0.000 claims abstract description 9
- 102000004882 Lipase Human genes 0.000 claims abstract description 8
- 239000004367 Lipase Substances 0.000 claims abstract description 8
- 108090001060 Lipase Proteins 0.000 claims abstract description 8
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims abstract description 8
- 235000019421 lipase Nutrition 0.000 claims abstract description 8
- 108010059892 Cellulase Proteins 0.000 claims abstract description 7
- 241000223198 Humicola Species 0.000 claims abstract description 7
- 229940106157 cellulase Drugs 0.000 claims abstract description 7
- 125000000217 alkyl group Chemical group 0.000 claims abstract description 6
- 102000013142 Amylases Human genes 0.000 claims abstract description 5
- 108010065511 Amylases Proteins 0.000 claims abstract description 5
- 235000019418 amylase Nutrition 0.000 claims abstract description 5
- 239000004382 Amylase Substances 0.000 claims abstract description 4
- UHPMCKVQTMMPCG-UHFFFAOYSA-N 5,8-dihydroxy-2-methoxy-6-methyl-7-(2-oxopropyl)naphthalene-1,4-dione Chemical compound CC1=C(CC(C)=O)C(O)=C2C(=O)C(OC)=CC(=O)C2=C1O UHPMCKVQTMMPCG-UHFFFAOYSA-N 0.000 claims abstract description 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 claims abstract description 3
- 241000223218 Fusarium Species 0.000 claims abstract description 3
- 229910052783 alkali metal Inorganic materials 0.000 claims abstract description 3
- 150000001340 alkali metals Chemical class 0.000 claims abstract description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 7
- 125000000129 anionic group Chemical group 0.000 claims description 6
- 239000003945 anionic surfactant Substances 0.000 claims description 6
- 229910052739 hydrogen Inorganic materials 0.000 claims description 6
- 239000001257 hydrogen Substances 0.000 claims description 6
- 230000000813 microbial effect Effects 0.000 claims description 5
- 239000002904 solvent Substances 0.000 claims description 5
- 239000000126 substance Substances 0.000 claims description 5
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 4
- 239000002736 nonionic surfactant Substances 0.000 claims description 4
- 230000002538 fungal effect Effects 0.000 claims description 3
- 229910052784 alkaline earth metal Inorganic materials 0.000 claims description 2
- 150000001342 alkaline earth metals Chemical group 0.000 claims description 2
- 150000003863 ammonium salts Chemical class 0.000 claims description 2
- 159000000007 calcium salts Chemical class 0.000 claims description 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims description 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims 1
- 125000003161 (C1-C6) alkylene group Chemical group 0.000 claims 1
- 125000002947 alkylene group Chemical group 0.000 abstract description 2
- 239000004753 textile Substances 0.000 abstract description 2
- 238000005406 washing Methods 0.000 abstract description 2
- 125000000954 2-hydroxyethyl group Chemical group [H]C([*])([H])C([H])([H])O[H] 0.000 abstract 1
- 238000004321 preservation Methods 0.000 abstract 1
- 235000019419 proteases Nutrition 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 6
- -1 alkylbenzene sulfonates Chemical class 0.000 description 6
- 102000035195 Peptidases Human genes 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 238000009472 formulation Methods 0.000 description 3
- 241000194108 Bacillus licheniformis Species 0.000 description 2
- 108010084185 Cellulases Proteins 0.000 description 2
- 102000005575 Cellulases Human genes 0.000 description 2
- 229910019142 PO4 Inorganic materials 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 239000011575 calcium Substances 0.000 description 2
- 239000002563 ionic surfactant Substances 0.000 description 2
- 235000021317 phosphate Nutrition 0.000 description 2
- 229920000058 polyacrylate Polymers 0.000 description 2
- 230000006641 stabilisation Effects 0.000 description 2
- 238000011105 stabilization Methods 0.000 description 2
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 2
- 150000003871 sulfonates Chemical class 0.000 description 2
- 239000010457 zeolite Substances 0.000 description 2
- 239000004711 α-olefin Substances 0.000 description 2
- IEORSVTYLWZQJQ-UHFFFAOYSA-N 2-(2-nonylphenoxy)ethanol Chemical compound CCCCCCCCCC1=CC=CC=C1OCCO IEORSVTYLWZQJQ-UHFFFAOYSA-N 0.000 description 1
- DUAWRLXHCUAWMK-UHFFFAOYSA-N 2-iminiopropionate Chemical compound CC(=[NH2+])C([O-])=O DUAWRLXHCUAWMK-UHFFFAOYSA-N 0.000 description 1
- TXPKUUXHNFRBPS-UHFFFAOYSA-N 3-(2-carboxyethylamino)propanoic acid Chemical compound OC(=O)CCNCCC(O)=O TXPKUUXHNFRBPS-UHFFFAOYSA-N 0.000 description 1
- CNGYZEMWVAWWOB-VAWYXSNFSA-N 5-[[4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-2-yl]amino]-2-[(e)-2-[4-[[4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-2-yl]amino]-2-sulfophenyl]ethenyl]benzenesulfonic acid Chemical compound N=1C(NC=2C=C(C(\C=C\C=3C(=CC(NC=4N=C(N=C(NC=5C=CC=CC=5)N=4)N(CCO)CCO)=CC=3)S(O)(=O)=O)=CC=2)S(O)(=O)=O)=NC(N(CCO)CCO)=NC=1NC1=CC=CC=C1 CNGYZEMWVAWWOB-VAWYXSNFSA-N 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 241000055915 Heterocoma lanuginosa Species 0.000 description 1
- 241001480714 Humicola insolens Species 0.000 description 1
- QPCDCPDFJACHGM-UHFFFAOYSA-N N,N-bis{2-[bis(carboxymethyl)amino]ethyl}glycine Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(=O)O)CCN(CC(O)=O)CC(O)=O QPCDCPDFJACHGM-UHFFFAOYSA-N 0.000 description 1
- ABLZXFCXXLZCGV-UHFFFAOYSA-N Phosphorous acid Chemical class OP(O)=O ABLZXFCXXLZCGV-UHFFFAOYSA-N 0.000 description 1
- 235000009470 Theobroma cacao Nutrition 0.000 description 1
- 229910021536 Zeolite Inorganic materials 0.000 description 1
- 239000011149 active material Substances 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 102000004139 alpha-Amylases Human genes 0.000 description 1
- 108090000637 alpha-Amylases Proteins 0.000 description 1
- 229940024171 alpha-amylase Drugs 0.000 description 1
- 229940025131 amylases Drugs 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 239000003899 bactericide agent Substances 0.000 description 1
- 244000240602 cacao Species 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 239000003093 cationic surfactant Substances 0.000 description 1
- CRQQGFGUEAVUIL-UHFFFAOYSA-N chlorothalonil Chemical compound ClC1=C(Cl)C(C#N)=C(Cl)C(C#N)=C1Cl CRQQGFGUEAVUIL-UHFFFAOYSA-N 0.000 description 1
- 150000001860 citric acid derivatives Chemical class 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical compound O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 description 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
- LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Natural products OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 1
- 239000002979 fabric softener Substances 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 230000010196 hermaphroditism Effects 0.000 description 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 229920000847 nonoxynol Polymers 0.000 description 1
- OSBMVGFXROCQIZ-UHFFFAOYSA-I pentasodium;[bis(phosphonatomethyl)amino]methyl-hydroxyphosphinate Chemical compound [Na+].[Na+].[Na+].[Na+].[Na+].OP([O-])(=O)CN(CP([O-])([O-])=O)CP([O-])([O-])=O OSBMVGFXROCQIZ-UHFFFAOYSA-I 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- UEZVMMHDMIWARA-UHFFFAOYSA-M phosphonate Chemical compound [O-]P(=O)=O UEZVMMHDMIWARA-UHFFFAOYSA-M 0.000 description 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 description 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000003760 tallow Substances 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
- C11D3/38663—Stabilised liquid enzyme compositions
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/88—Ampholytes; Electroneutral compounds
- C11D1/94—Mixtures with anionic, cationic or non-ionic compounds
Abstract
Description
【発明の詳細な説明】
〔産業上の利用分野〕
本発明は、商業および家庭用の双方の織物の如き硬い表
面および柔い品物を含む広範囲の品目を洗浄するための
安定化酵素水性液体組成物に関する。DETAILED DESCRIPTION OF THE INVENTION Field of the Invention The present invention provides a stabilized enzyme aqueous liquid composition for cleaning a wide variety of items, including hard surfaces and soft items such as textiles, both commercial and domestic. relating to things.
〔従来技術および発明が解決しようとする課題〕水性液
体酵素洗剤は、周知技術である。液体洗剤に配合される
酵素は、大部分バシラスプロテアーゼであるが、従来技
術はまたバシラスブロテアーゼ以外の酵素、例えば他の
酵素タイプ（例えばアミラーゼ、リパーゼおよびセルラ
ーゼ）並びに非バシラス起源の酵素（例えば真菌酵素）
の配合が有用であることも公知である。このような組成
物が出あう主な問題は、かかる組成物中の酵素の十分な
る保存安定性の確保の問題である。[Prior Art and Problems to be Solved by the Invention] Aqueous liquid enzyme detergents are well known in the art. Although the enzymes formulated in liquid detergents are mostly Bacillus proteases, the prior art also uses enzymes other than Bacillus proteases, such as other enzyme types (e.g. amylases, lipases and cellulases) as well as enzymes of non-Bacillus origin (e.g. fungal enzyme)
It is also known that formulations of The main problem encountered with such compositions is that of ensuring sufficient storage stability of the enzymes in such compositions.
〔従来技術および発明が解決しようとする課題〕従来技
術は、液体洗浄中の酵素の安定性を広範囲に扱っている
。以下の内容は公知である。すなわち、多数の普通に用
いられる洗剤成分、例えばアニオン界面活性剤および洗
剤用ビルダーは、洗剤の安定性を減少させる。従来技術
はまた、洗浄力活性のない種々の物質が酵素安定剤とし
て配合され得ることをも捉案じている。PRIOR ART AND PROBLEM TO BE SOLVED BY THE INVENTION The prior art has extensively addressed the stability of enzymes during liquid washing. The following content is publicly known. That is, many commonly used detergent ingredients, such as anionic surfactants and detergent builders, reduce detergent stability. The prior art also recognizes that various substances without detersive activity may be formulated as enzyme stabilizers.
また次の内容も言及されうる。すなわち、特開昭５８−
１９４．８０６および特開昭５８−０６９，８０Ｂは、
アミラーゼの保存安定性を改善するため歯科用ペースト
にイミダシリン両性界面活性剤の配合を提案している。The following may also be mentioned: That is, JP-A-58-
194.806 and JP-A-58-069,80B,
In order to improve the storage stability of amylase, we have proposed incorporating imidacillin amphoteric surfactant into dental paste.
この教示は、明らかに洗剤において用いられるものでは
ない。This teaching is clearly not intended for use in detergents.
本発明の目的は、改良された保存安定性を有する洗剤を
含有する液体洗剤組成物を提供することにある。It is an object of the present invention to provide liquid detergent compositions containing detergents with improved storage stability.
本発明の目的は、以下の要素（ａ）および（ｂ）からな
る安定化酵素水性液体洗剤組成物を提供することによっ
て達成される：
（ａ）微生物酵素の有効量
（ｂ、）次式■：
以下余ｅ
Ｂ
（式中、Ｒは所望によりヒドロキシルまたはカルボキシ
ルによって置換されていてもよいｃｌ、２アルキル基で
あり、
ＡはＣＯもしくは０ＣＨｚＣＨｔであり、ｎはＯ又は１
であり、
Ｒ８は水素もしくはｃ＋−ｈアルキル基でありＸは２も
しくは３であり、
ｙは０〜４であり、
ＱはＣＨｚＣＨｚＯＨ又ハｌｈｃＯＯＭ （コ、：、
テＲ！ ハＣＩ〜＆アルキレン基であり、Ｍは水素又は
アルカリ金属、アルカリ土類金属、アンモニウムもしく
は置換アンモニウムである）であり、更に
Ｂは水素であるか又は上記意味の基Ｑである）で表わさ
れる両性界面活性剤約１〜５０重量％。The objects of the present invention are achieved by providing a stabilized enzyme aqueous liquid detergent composition consisting of the following elements (a) and (b): (a) an effective amount of a microbial enzyme; (b) the following formula: : Hereinafter, R is optionally substituted with hydroxyl or carboxyl, Cl, 2 alkyl group, A is CO or 0CHzCHt, n is O or 1
, R8 is hydrogen or a c+-h alkyl group, X is 2 or 3, y is 0 to 4, and Q is CHzCHzOH or halcOOM (co, :,
TeR! is a CI~ & alkylene group, M is hydrogen or an alkali metal, alkaline earth metal, ammonium or substituted ammonium), and B is hydrogen or a group Q as defined above) About 1-50% by weight of an amphoteric surfactant.
特に好ましい式■の化合物は次式■：
（式中、Ｒは式■で定義した意味であり、ｙは３又は４
である）
を有する。Particularly preferred compounds of formula (1) are the following formula (2): (wherein R has the meaning defined in formula (2), and y is 3 or 4
).
式■において、Ｒは好ましくは飽和の、未分技でかつ未
置換Ｃ，−Ｃ，。アルキルである。基Ｒの好ましい例は
、ココ酸（主にＣＩ ｔ＋＋ ４）並びにタロー酸（主
にＣ１，−Ｉｌ＋）から誘導されるものである。In formula (1), R is preferably saturated, undivided and unsubstituted C, -C,. It is an alkyl. Preferred examples of radicals R are those derived from cocoa acid (mainly CI t++ 4) as well as tallow acid (mainly C1, -Il+).
本発明によれば、酵素安定化はそれ自身洗浄力活性であ
る成る種のタイプの両性界面活性剤の導入によって達成
される。かくして、酵素安定化の目的に対する非活性物
質のみの導入は避けることができるかもしくは減少せし
めることができる。According to the invention, enzyme stabilization is achieved by the introduction of a type of amphoteric surfactant which is itself detergent active. Thus, the introduction of only inactive substances for enzyme stabilization purposes can be avoided or reduced.
盈生皇鼠案
本組成物に対し適当な微生物酵素には、プロテアーゼ、
リパーゼ、アミラーゼおよびセルラーゼが含まれている
。酵素は微生物源、例えばバシラスおよび真菌から由来
する。洗剤酵素の幾つかの特定の例を以下に述べるが、
各々は酵素タイプ、微生物起源および商品番号および／
又は特許公報によって特定される。Suitable microbial enzymes for the composition include proteases,
Contains lipase, amylase and cellulase. Enzymes are derived from microbial sources such as Bacillus and fungi. Some specific examples of detergent enzymes are mentioned below:
Each includes enzyme type, microbial origin and product number and/or
or as specified by the patent publication.
一バシラス、特にＢ、リケニフォルミス由来のプロテア
ーゼ（例えばアルカラーゼ（商標））および米国特許３
，７２３．２５０による好アルカロイドパシラス菌株由
来のプロテアーゼ（例えばサビナーゼ（商標）およびエ
スペラーゼ（商標））（全てノボインダストリー社より
入手可能）−バシラス、特にバシラスリケニフォルミス
のα−アミラーゼ。ターミル（商標）（ノボインダスト
リー社）。Proteases from Bacillus, particularly B. licheniformis (e.g. Alcalase™) and U.S. Pat.
, 723.250 from alkalophilic Pacillas strains (such as Savinase™ and Esperase™) (all available from Novo Industries) - α-amylase of Bacillus, especially Bacillus licheniformis. Termil (trademark) (Novo Industries).
一フサリアム、特にＦ、オキシスポラムのプロテアーゼ
、米国特許３．６５２．３９９ （タケダ）−ＤＫ ６
３７６／８７によるプロテアーゼ（ノボインダストリー
社）
一ヒューミコラ、特にＨ，インソレンスのセルラーゼ、
セルザイム（商標）（ノボインダストリー社）、米国特
許４，４３５．３０７（ノボインダストリー社）。Fusarium, especially F, Oxysporum protease, US Pat. No. 3.652.399 (Takeda) - DK 6
376/87 (Novo Industries) - cellulases of Humicola, especially H. insolens;
Cellzyme(TM) (Novo Industries, Inc.), US Pat. No. 4,435.307 (Novo Industries, Inc.).
−ヒューミコラ、特にＨ，ラヌギノザのリパーゼ、リポ
ラーゼ（商標）（ノボインダストリー社）、ヨーロッパ
特許１７７．１８３（ノボインダストリー社）。- Lipase of Humicola, especially H. lanuginosa, Lipolase™ (Novo Industries), European Patent No. 177.183 (Novo Industries).
本発明の洗剤は、２種又はそれ以上の洗剤用酵素を含有
することができる０例として、上記酵素の任意の２種、
特にバシラスプロテアーゼおよび上記酵素の任意の一種
を組み合わせることができる。The detergent of the present invention may contain two or more detergent enzymes, including any two of the above enzymes,
In particular, Bacillus protease and any one of the enzymes mentioned above can be combined.
工Ｉの ゝ
式Ｉを有する両性界面活性剤の商業的に入手可能な例に
は、プリファツト１５１、プリファツト１５４、プリフ
ァツト１５１Ｃ，プリファツト１６１Ｃ（ヘンケル社か
ら入手可能製品）、アムホラムＣＰ１、グイアホラムＣ
ＰＩ、トリアムホラムＣＰＩ、およびポリアムホラム（
七カから入手可能製品）、およびアムホラク７ＴＸおよ
びアムホラクＸＣＯ−３０（ケノベルから入手可能製品
）が含まれる。後者の２製品の化学式は次の通りである
：Ｒ＝ＣＩ＆−１１１
Ｘ＝−ＣＨｚ−ＣＯＯＮａ
本発明の洗剤組成物は、また通常非イオン界面活性剤、
例えば約３〜２０重量を存する。更に、組成物は所望に
よりカチオン界面活性剤および／又は第二の両性界面活
性剤、例えば約３〜１５重世％を含有する０組成物は本
質的にアニオン性界面活性剤を含まないことが好ましい
。何故なら、これは幾分酵素を不安定化させるからであ
る。Commercially available examples of amphoteric surfactants having Formula I include Prefat 151, Prefat 154, Prefat 151C, Prefat 161C (products available from Henkel), Amphoram CP1, Guiaforam C.
PI, triamphorum CPI, and polyamphorum (
Amhorac 7TX and Amhorac XCO-30 (products available from Kenobel). The chemical formulas of the latter two products are as follows: R=CI&-111
For example, about 3 to 20 weight. Additionally, the composition may optionally contain a cationic surfactant and/or a second amphoteric surfactant, e.g., about 3 to 15%, but the composition may be essentially free of anionic surfactant. preferable. This is because this destabilizes the enzyme somewhat.
安定な界面活性剤の例は次の通りであるニー非イオン界
面活性剤：ノニルフェノールエトキシレート、アルコー
ルエトキシレート。Examples of stable surfactants are nonionic surfactants: nonylphenol ethoxylate, alcohol ethoxylate.
−アニオン界面活性剤：直鎖アルキルベンゼンスルホナ
ート、二級アルカンスルホナート、アルコールエトキシ
レートスルホナート、α−オレフィンスルホナートであ
る。- Anionic surfactants: linear alkylbenzene sulfonates, secondary alkanesulfonates, alcohol ethoxylate sulfonates, α-olefin sulfonates.
第二の両性界面活性剤：イミノジプロピオナート（例え
ばアムホラーゼＹＣＥ、ケノベルＡＢ（スウェーデン）
から人手可能）およびイミノプロピオナート。Second amphoteric surfactant: iminodipropionate (e.g. Amphorase YCE, Kenobel AB (Sweden)
) and iminopropionate.
弛１１岬分
本発明の液体洗剤は、水性であり、例えば２０〜７０％
の水および０〜２０％の溶剤を含有するか、又は１〜２
％の水および５〜２５％の溶剤を含有する。水分含量が
５０％を超えても満足な酵素安定性が得られる。別に、
木質的に水を含有しなくてもよ（（例えば、水分含ｆｆ
１１％未満）、更に典型的には１０〜３０％の溶剤を含
有する。The liquid detergent of the present invention is aqueous, for example, 20 to 70%
of water and 0-20% solvent, or 1-2
% water and 5-25% solvent. Satisfactory enzyme stability is obtained even when the water content exceeds 50%. Separately,
Wood does not have to contain water (for example, water content ff
11%), more typically 10-30%.
典型的溶剤は、−価および二価の低級アルコールおよび
グリコールエーテルである。Typical solvents are -hydric and dihydric lower alcohols and glycol ethers.
本発明の洗剤組成物は、ビルドされる（すなわち、洗剤
ビルダーを含む）こともでき、あるいはビルドされなく
ともよい（すなわち、本質的に洗剤ビルダーを含有しな
い）。酵素安定性は、−Ｓにビルダー含有組成物におい
て良好であるが、洗浄力の改善のためにはビルダーを含
むことが望ましい、ビルドされた組成物は、典型的には
約１〜４０重世％のビルダー、例えばゼオライト、ホス
フェート、ホスフォナート、シトレート、ＮＴＡ 。The detergent compositions of the present invention can be built (ie, contain detergent builders) or unbuilt (ie, essentially free of detergent builders). Although enzyme stability is better in builder-containing compositions, it is desirable to include a builder for improved detergency; the built compositions typically have about 1 to 40 % builders such as zeolites, phosphates, phosphonates, citrates, NTA.
ＥＤＴＡ又はＤＴＰＡを含有する。Contains EDTA or DTPA.
可溶性カルシウム塩は、Ｃａとして約１〜２゜μｒｒｒ
ｏｌ／Ｒを与える量で好ましく含まれる。何故なら、カ
ルシウムは洗剤酵素を安定化させるからである。Soluble calcium salt is about 1-2゜μrrr as Ca.
It is preferably included in an amount that provides ol/R. This is because calcium stabilizes detergent enzymes.
ｐＨは典型的には中性もしくはアルカリ性であり、特に
８〜工０のｐＨが好ましい。The pH is typically neutral or alkaline, with a pH of 8 to 0 being particularly preferred.
組成物はまた意図した使用に応じて、添加剤、例えば布
帛コンディショナー（例えば第四級アンモニウム塩、典
型的には１〜５％）、起泡増進剤（例えば１〜５％）、
殺菌剤（例えば１〜５％）、螢光増白剤（例えば０．１
〜１％）、洗料（例えば０．１〜１％）および香料（例
えば０．１〜１％）。The compositions may also contain additives, depending on the intended use, such as fabric conditioners (e.g. quaternary ammonium salts, typically 1-5%), suds boosters (e.g. 1-5%),
Bactericide (e.g. 1-5%), fluorescent brightener (e.g. 0.1%)
~1%), detergents (e.g. 0.1-1%) and fragrances (e.g. 0.1-1%).
種々の水分含量を有する、本質的にビルドされていない
か、あるいはゼオライトビルド液体洗剤の試料を次の組
成物（重量％、活性物質として）を調製した。Samples of essentially unbuilt or zeolite built liquid detergents with various moisture contents were prepared in the following compositions (% by weight, as active material):
以下余白
跣−」壮
水
トリエタノールアミン
脂肪酸（Ｃ１□−０１，）
エタノール
ポリアクリレート
プロピレングリコール ５３
ゼオライトＳ
ホスフェート ２１．６ＣａＣ１ｚ
・２＋１２０ ０．１ ０．１非イ
オン界面活性剤 １０８アニオン性／両性界
面活性剤 ６４．８１００％ １００％
調整ｐｉ ９．０ ９．０
ポリアクリレートは、アルコスパーゼ（Ａｌｃｏｓ−ｐ
ｅｒｓｅ） ４０９であり、更にホスホネートはデクエ
スト（Ｄｅｑｕｅｓｔ）２００６であった。非イオン界
面活性剤は、アルコールエトキシレートであり、次のド
パノールタイプ（シェル）：２５〜９．２３−６．５お
よび２３−３の３：１：１の割合から成っていた。Below are the blanks below: Sosui Triethanolamine Fatty Acid (C1□-01,) Ethanol Polyacrylate Propylene Glycol 53 Zeolite S Phosphate 21.6CaC1z
・2+120 0.1 0.1 Nonionic surfactant 108 Anionic/Ampholytic surfactant 64.8 100% 100% Adjustment pi 9.0 9.0
Polyacrylate is made of alcospase (Alcos-p).
409, and the phosphonate was Dequest 2006. The nonionic surfactant was an alcohol ethoxylate and consisted of the following dopanol types (shell): 25-9.23-6.5 and 23-3 in a 3:1:1 ratio.
Ｂ ＢＴ Ｚｌ
５４．９％ ６４．９％ ６５，６％
１０ ８ ２．８
７ ５．６
０．７
０．７
１８．９
０．１
４．２
１００％
９．０
各製剤中のアニオン性／両性界面活性剤は次の一種であ
った・
対 照ニ
ーＬＡＳ （アニオン性）、直鎖アルキルベンゼンスル
ホナート、スルホソフト（ベロール）、−３ＡＳ （ア
ニオン性）、第二級アルカンスルホナート、Ｈｏ５ｔａ
ｐｕｒ ＳＡＳ ６０（ヘキスト）ＡＥＳ （アニオン
性）、アルコールエトキシレートスルホナート、ドパノ
ール ２５−３５ （シェル）
−ＡＯ３（アニオン性）、αオレフインスルホナート（
エチル（ａｒｐ、）
本発明：
一アムホラーク７ＴＸ（本発明の両性）−アムホラーク
ＸＣ０−３０（本発明の両性）−７ＴＸ＋ＬＡＳ、２
： ｌの割合
−ＴＴＸ＋アムホラークＹＣＥ （第二の両性）、３：
１の割合、次の酵素の一つを、各洗剤試料に加えた。B BT Zl 54.9% 64.9% 65.6% 10 8 2.8 7 5.6 0.7 0.7 18.9 0.1 4.2 100% 9.0 Anionicity in each formulation /Ampholytic surfactants were one of the following: Control LAS (anionic), linear alkylbenzene sulfonate, sulfosoft (verol), -3AS (anionic), secondary alkanesulfonate, Ho5ta
pur SAS 60 (Hoechst) AES (anionic), alcohol ethoxylate sulfonate, dopanol 25-35 (shell) -AO3 (anionic), alpha olefin sulfonate (
Ethyl (arp,) Invention: 1 Amhorak 7TX (ampholytic of the invention) - Amhorak XC0-30 (ampholytic of the invention) -7TX+LAS, 2
: Proportion of l - TTX + Amhorak YCE (second hermaphrodite), 3:
One part of the following enzymes was added to each detergent sample.
一１％のサビナーゼ８．ＯＬ（好アルカロバシラスプロ
テアーゼ）
−１，５％のセルザイム（ヒューミコラセルラーゼ）−
リボラーゼ（真菌リパーゼ）。-1% Savinase8. OL (alkalobacillus protease) -1.5% Cellzyme (humicola cellulase) -
Ribolase (fungal lipase).
試料を３７°Ｃで２週間保存し、酵素活性を保存前およ
び保存後に測定し、結果を初期活性の残留活性（％）と
して表わした。Samples were stored at 37°C for 2 weeks, and enzyme activity was measured before and after storage, and results were expressed as residual activity (%) of initial activity.
試みた全ての製剤に対し、アニオン性界面活性剤を本発
明による両性界面活性剤で完全に置き代えた場合、酵素
の貯臓安定性が改善されることは明白である。It is clear that for all formulations tried, the storage stability of the enzyme is improved if the anionic surfactant is completely replaced by the amphoteric surfactant according to the invention.
Claims (1)
ルによって置換されていてもよいＣ＿７＿〜＿２＿２ア
ルキル基であり、 ＡはＣＯもしくはＯＣＨ＿２ＣＨ＿２であり、ｎは０又
は１であり、 Ｒ＿１は水素もしくはＣ＿１＿〜＿６アルキル基であり
ｘは２もしくは３であり、 ｙは０〜４であり、 ＱはＣＨ＿２ＣＨ＿２ＯＨ又はＲ＿２ＣＯＯＭ（ここで
Ｒ＿２はＣ＿１＿〜＿６アルキレン基であり、Ｍは水素
又はアルカリ金属、アルカリ土類金属、アンモニウムも
しくは置換アンモニウムである）であり、更に Ｂは水素であるか又は上記意味の基Ｑである）で表わさ
れる両性界面活性剤約１〜５０重量％を含んでなる安定
化酵素水性液体洗剤組成物。 ２、前記両性界面活性剤が次式II： ▲数式、化学式、表等があります▼（II） （式中、Ｒは式 I で定義した意味であり、ｙは３又は
４である） を有する、特許請求の範囲第１項記載の洗剤組成物。 ３、前記酵素がバシラス酵素、好ましくはプロテアーゼ
、アミラーゼもしくはセルラーゼである、特許請求の範
囲第１項又は第２項記載の洗剤組成物。 ４、前記酵素が真菌洗剤酵素、好ましくはプロテアーゼ
、リパーゼもしくはセルラーゼである、特許請求の範囲
第１項又は第２項記載の洗剤組成物。 ５、前記酵素が、フサリアムプロテアーゼ、ヒューミコ
ラリパーゼもしくはヒューミコラセルラーゼである、特
許請求の範囲第４項記載の洗剤組成物。 ６、更に第２の洗剤用酵素の有効量を含有する、特許請
求の範囲第１項から第５項までのいずれか１項に記載の
洗剤組成物。 ７、前記両性界面活性剤約３〜４０重量％を含有する、
特許請求の範囲第１項から第６項までのいずれか１項に
記載の洗剤組成物。 ８、更に非イオン性界面活性剤約１〜２０重量％を含有
する、特許請求の範囲第１項から第７項までのいずれか
１項に記載の洗剤組成物。 ９、更にアニオン性および／又は第２の両性界面活性剤
を含有する、特許請求の範囲第１項から第８項までのい
ずれか１項に記載の洗剤組成物。 １０、実質的にアニオン性界面活性剤が存しない、特許
請求の範囲第１項から第９項までのいずれか１項に記載
の洗剤組成物。 １１、約２０〜７０重量％の水および０〜約２０重量％
の溶剤を更に含有する、特許請求の範囲第１項から第１
０項までのいずれか１項に記載の洗剤組成物。 １２、約１０〜３０％の溶剤を含有し、更に本質的に水
が存在しない特許請求の範囲第１項から第１０項までの
いずれか１項に記載の洗剤組成物。 １３、実質的に洗剤用ビルダーを含まない、特許請求の
範囲第１項から第１２項までのいずれか１項に記載の洗
剤組成物。 １４、１〜４０重量％の洗剤ビルダーを含有する、特許
請求の範囲第１項から第１２項までのいずれか１項に記
載の洗剤組成物。 １５、１ｌ当たり約１〜２０ミリモルを与える量の可溶
性カルシウム塩を含有する、特許請求の範囲第１項から
第１４項までのいずれか１項に記載の洗剤組成物。[Claims] 1. (a) an effective amount of a microbial enzyme, and (b) the following formula I: ▲Mathematical formulas, chemical formulas, tables, etc.▼(I) (wherein R is optionally replaced by hydroxyl or carboxyl) is an optionally substituted C_7_-_2_2 alkyl group, A is CO or OCH_2CH_2, n is 0 or 1, R_1 is hydrogen or a C_1_-_6 alkyl group, x is 2 or 3, y is 0-4, Q is CH_2CH_2OH or R_2COOM (where R_2 is a C_1___6 alkylene group and M is hydrogen or an alkali metal, alkaline earth metal, ammonium or substituted ammonium), and B is 1. A stabilized enzyme aqueous liquid detergent composition comprising from about 1 to 50% by weight of an amphoteric surfactant represented by hydrogen or group Q as defined above. 2. The amphoteric surfactant has the following formula II: ▲Mathematical formula, chemical formula, table, etc.▼(II) (wherein R has the meaning defined in Formula I, and y is 3 or 4) , a detergent composition according to claim 1. 3. The detergent composition according to claim 1 or 2, wherein the enzyme is a Bacillus enzyme, preferably protease, amylase or cellulase. 4. A detergent composition according to claim 1 or 2, wherein the enzyme is a fungal detergent enzyme, preferably a protease, lipase or cellulase. 5. The detergent composition according to claim 4, wherein the enzyme is Fusarium protease, humicola lipase or humicola cellulase. 6. The detergent composition according to any one of claims 1 to 5, further comprising an effective amount of a second detergent enzyme. 7. Containing about 3 to 40% by weight of the amphoteric surfactant,
A detergent composition according to any one of claims 1 to 6. 8. A detergent composition according to any one of claims 1 to 7, further comprising about 1 to 20% by weight of a nonionic surfactant. 9. The detergent composition according to any one of claims 1 to 8, further comprising an anionic and/or a second amphoteric surfactant. 10. The detergent composition according to any one of claims 1 to 9, which is substantially free of anionic surfactants. 11. About 20 to 70% water and 0 to about 20% by weight
Claims 1 to 1 further comprising a solvent of
The detergent composition according to any one of items 0 to 0. 12. A detergent composition according to any one of claims 1 to 10, containing about 10-30% solvent and further essentially free of water. 13. The detergent composition according to any one of claims 1 to 12, which is substantially free of detergent builder. 14. Detergent composition according to any one of claims 1 to 12, containing from 1 to 40% by weight of detergent builder. 15. A detergent composition according to any one of claims 1 to 14, containing an amount of soluble calcium salt giving about 1 to 20 mmol per liter.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK4039/88 | 1988-07-20 | ||
| DK403988A DK403988D0 (en) | 1988-07-20 | 1988-07-20 | STABILIZED ENZYMATIC LIQUID DETERGENT |
| DK525488A DK525488D0 (en) | 1988-09-21 | 1988-09-21 | STABILIZED ENZYMATIC LIQUID DETERGENT |
| DK5254/88 | 1988-09-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH0241398A true JPH0241398A (en) | 1990-02-09 |
Family
ID=26067323
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP29479988A Pending JPH0241398A (en) | 1988-07-20 | 1988-11-24 | Liquid, stabilized enzyme detergent composition |
Country Status (2)
| Country | Link |
|---|---|
| EP (1) | EP0352244A3 (en) |
| JP (1) | JPH0241398A (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06248290A (en) * | 1993-02-26 | 1994-09-06 | Miyoshi Oil & Fat Co Ltd | Cleaning agent composition |
| JP2000169897A (en) * | 1998-12-04 | 2000-06-20 | Kao Corp | Liquid detergent composition |
| JP2002034558A (en) * | 2000-07-21 | 2002-02-05 | Nof Corp | Stabilized proteolytic enzyme and its usage |
| JP2010220607A (en) * | 2009-02-27 | 2010-10-07 | Konan Gakuen | Composition for improving enzyme activity, and use of the same |
| JP2014522896A (en) * | 2011-07-12 | 2014-09-08 | クラリアント・インターナシヨナル・リミテツド | Use of a combination of secondary paraffin sulfonate and amylase to enhance the cleaning capacity of a liquid laundry detergent |
| JP2014523469A (en) * | 2011-07-12 | 2014-09-11 | クラリアント・インターナシヨナル・リミテツド | Use of secondary paraffin sulphonate to enhance the cleaning ability of the enzyme |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5562894A (en) * | 1991-08-09 | 1996-10-08 | Regents Of The University Of California | Amino-acyl-type and catecholamine-type contrast agents for MRI |
| PL172923B1 (en) * | 1992-08-25 | 1997-12-31 | Unilever Nv | Liquid cleaning compositions containing primary alcohol sulfides and non-ionic surfactants |
| AU5175893A (en) * | 1992-10-09 | 1994-06-22 | Unilever Plc | Hard-surface cleaning compositions comprising solvent, surfactant and lipase |
| US5356800A (en) * | 1992-11-30 | 1994-10-18 | Buckman Laboratories International, Inc. | Stabilized liquid enzymatic compositions |
| ES2148479T3 (en) * | 1993-12-03 | 2000-10-16 | Buckman Labor Inc | STABILIZATION OF ENZYMES THROUGH COPOLYMER SEQUENCES. |
| US5474701A (en) * | 1994-01-21 | 1995-12-12 | Buckman Laboratories International, Inc. | Enzymes for recreational water |
| DE19529587A1 (en) | 1995-08-11 | 1997-02-13 | Henkel Ecolab Gmbh & Co Ohg | Means for cleaning protective work clothing |
| CA2242651A1 (en) * | 1997-07-22 | 1999-01-22 | Calgon Corporation | Composition and method for cleaning surfaces |
| AU2207099A (en) * | 1997-12-24 | 1999-07-19 | Genencor International, Inc. | An improved method of assaying for a preferred enzyme and/or preferred detergentcomposition |
| US6342381B1 (en) | 1998-02-27 | 2002-01-29 | Buckman Laboratories Internationals, Inc. | Enzyme stabilization with pre-superpolyamide or pre-fiber-forming polyamide oligomers |
| FI121711B (en) | 2009-04-30 | 2011-03-15 | Ab Enzymes Oy | Fungal serine protease and its use |
| FI121712B (en) | 2009-04-30 | 2011-03-15 | Ab Enzymes Oy | New fungal protease and its use |
| FI121851B (en) | 2009-07-08 | 2011-05-13 | Ab Enzymes Oy | Fungal protease and its use |
| FI123942B (en) | 2010-10-29 | 2013-12-31 | Ab Enzymes Oy | Variants of fungal serine protease |
| FI123425B (en) | 2011-03-31 | 2013-04-30 | Ab Enzymes Oy | PROTEASE ENZYME AND ITS USES |
| US9745543B2 (en) * | 2012-09-10 | 2017-08-29 | Ecolab Usa Inc. | Stable liquid manual dishwashing compositions containing enzymes |
| DE102014226293A1 (en) * | 2014-12-17 | 2016-06-23 | Henkel Ag & Co. Kgaa | Detergent with improved stain removal |
| CN114774213B (en) * | 2021-05-26 | 2023-10-31 | 浙江施维康生物医学材料有限公司 | Detergent for textiles and preparation method thereof |
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| CA940070A (en) * | 1968-12-23 | 1974-01-15 | Jim S. Berry | Stabilized aqueous enzyme composition |
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| JPS58132098A (en) * | 1982-02-01 | 1983-08-06 | 花王株式会社 | Detergent composition |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06248290A (en) * | 1993-02-26 | 1994-09-06 | Miyoshi Oil & Fat Co Ltd | Cleaning agent composition |
| JP2000169897A (en) * | 1998-12-04 | 2000-06-20 | Kao Corp | Liquid detergent composition |
| JP2002034558A (en) * | 2000-07-21 | 2002-02-05 | Nof Corp | Stabilized proteolytic enzyme and its usage |
| JP2010220607A (en) * | 2009-02-27 | 2010-10-07 | Konan Gakuen | Composition for improving enzyme activity, and use of the same |
| JP2014522896A (en) * | 2011-07-12 | 2014-09-08 | クラリアント・インターナシヨナル・リミテツド | Use of a combination of secondary paraffin sulfonate and amylase to enhance the cleaning capacity of a liquid laundry detergent |
| JP2014523469A (en) * | 2011-07-12 | 2014-09-11 | クラリアント・インターナシヨナル・リミテツド | Use of secondary paraffin sulphonate to enhance the cleaning ability of the enzyme |
Also Published As
| Publication number | Publication date |
|---|---|
| EP0352244A2 (en) | 1990-01-24 |
| EP0352244A3 (en) | 1990-12-27 |
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