JPH0239548Y2 - - Google Patents

Description

[Detailed Description of the Invention] [Industrial Application Field] The present invention relates to a stacked dialyzer.

[Conventional technology and its problems]

A conventional stacked dialyzer has a mesh having a network structure arranged as a spacer between flat dialysis membranes. Therefore, if the membrane spacing is made smaller in an attempt to increase dialysis efficiency, the flow resistance due to the mesh will increase, and problems such as bubble escape will occur.
There was a limit to reducing the distance between the membranes.

Furthermore, with stacked dialyzers, it is necessary to take precautions against liquid leakage and sideways shifting of the stacked members, but conventional dialyzers have a complex structure due to this, and it is not easy to install ports.

The present invention was developed in view of the above circumstances, and its purpose is to provide a laminated dialyzer that does not have the above-mentioned drawbacks, has a small membrane gap, and does not cause increased flow resistance or problems with bubble escape. Our goal is to provide the following.

A further object of the present invention is to provide a laminated dialyzer that has a simple configuration, can prevent liquid leakage and lateral displacement of the laminated member, and is easy to attach ports.

[Means and actions for solving problems]

According to the present invention, in order to achieve the above object,
The dialysis membrane is placed on a flat rectangular dialysis membrane with notches at the four corners or in a flat tube-shaped dialysis membrane with notches at the four corners. The fibers are arranged in parallel at a predetermined interval, and the edges of the dialysis membrane on both sides of the fiber row have a length equivalent to the length of the fibers and a thickness comparable to the diameter of the fibers. In addition, a strip-shaped side film with notches provided at both ends of the same long side is arranged facing outward so that the notches correspond to the notches of the dialysis membrane, for each layer or The fibers are laminated alternately so that the fiber arrangement direction within each tube and between the tubes is perpendicular, and a frame-shaped packing is attached to the notch of the obtained laminate, and a port is fitted into the packing. A multilayer dialyzer is provided.

In this way, by arranging a large number of fibers between the dialysis membranes in parallel in the liquid flow direction at a predetermined interval, the liquid flows smoothly, and even if the membrane spacing is small, there is no increase in flow resistance or bubble loss. High dialysis efficiency can be obtained without causing problems such as.

Furthermore, the structure is such that notches are formed at the four corners of the laminate, and frame-shaped gaskets are attached to these parts, so that liquid leakage can be easily prevented with a simple structure, and at the same time, the laminate can be easily prevented from leaking. It also prevents sideways slipping. In addition, frame-shaped gaskets are attached to the notches at the four corners of the laminate, which is alternately laminated so that the fiber arrangement direction of each layer is perpendicular. Since each port is fitted, the structure of the port is simple and its installation is also easy.

〔Example〕

Hereinafter, the present invention will be described in detail with reference to the accompanying drawings showing embodiments of the present invention.

FIG. 1 is an explanatory diagram showing the structure and arrangement of the spacer of the stacked dialyzer according to the present invention. A large number of fibers 1 having a length equal to the length of one side of the dialysis membrane 3 are arranged in parallel, and fibers are provided at the edges of the dialysis membrane 3 on both sides of the fiber row to prevent side leakage of liquid. A side film 2 in the form of a strip having a length equal to the length of the membrane and a thickness comparable to the diameter of the fibers is arranged and sealed to the dialysis membrane 3 using a sealing agent. Further, in order to facilitate the installation to the port constituting the housing of the dialyzer and to ensure tightness, notches 4 are provided at both ends of the same long side of the side film 2. are placed facing outward. In addition, dialysis membrane 3
Similar notches are also provided at the four corners. A large number of layers arranged in this manner are alternately stacked such that the fiber arrangement direction of each layer is perpendicular.
By this, blood and dialysate each have 1 fiber
As well as flowing in the axial direction of the
That is, blood flows in a fixed direction in every other layer, and dialysate flows in a direction perpendicular to the blood flow direction in every other layer across the blood flowing layer.

Furthermore, since arranging fibers one by one is complicated and difficult to operate, we developed a network structure in which either the warp or the weft can be dissolved and removed after chemical treatment, similar to how nylon is dissolved in a hydrochloric acid solution. After the mesh is placed between the dialysis membranes and the lamination is completed as described above, either the warp or the weft is dissolved and removed by chemical treatment, and the fibers are densely packed. can be arranged in

The fibers 1 arranged as described above are compressed from above and below by the dialysis membrane 3 and the film 2 because their diameter is about the same as the thickness of the side film 2, and are fixed between the dialysis membranes 3. .

By the way, when the arrangement of fibers is relatively sparse, the dialysis membrane and side film bend at the interfiber sites, creating gaps between the dialysis membrane of one layer and the side film of the other layer. , there is a risk of liquid leakage. In this case, as shown in FIG. 2, frame-shaped films 5 having a rectangular outer shape and internal space are placed above and below the fiber row and the side films on both sides thereof, and the side films 2 and the frame The shaped films 5 are adhered and laminated in the direction of the arrow. In this case, the shape of the frame-shaped film 5 is such that cutouts 6 of a shape corresponding to the cutouts 4 provided at both ends of the side film 2 are provided at the four corners of a square with side lengths equal to the length of the fibers 1. Notches 7 are similarly provided at the four corners of the dialysis membrane 3. In this case, it is better to make each of the notches 4, 6, and 7 into a rectangle with the long side approximately twice as long as the short side, so that the notches 4, 6, and 7 can be used as blood entrances and exits when attached to a port later as shown in Figure 3. This is preferable because it is easy to attach gaskets to both the inlet and outlet of the dialysate, and it is possible to completely prevent liquid leakage.

By configuring it in this way, the rigidity of the entire spacer can be increased, and even when the fibers are sparsely arranged, it is possible to prevent gaps from forming between the dialysis membrane and the side film. At the same time, outflow of fibers can also be prevented. Frame-shaped films include metal,
Various materials such as hard synthetic resin can be used. Note that it is of course possible to arrange the frame-shaped film only between the fiber row, the side film, and the dialysis membrane.

Next, the dialyzer is installed in a third manner.
As shown in the figure. Presser plates 9 are placed above and below the dialysis membrane and spacer stack 8 to apply pressure evenly to the stack 8. The shape of the presser plate 9 corresponds to the shape of the laminate 8. Reference numeral 11 denotes a liquid leakage prevention gasket that also serves to prevent the laminated member from shifting laterally. This gasket 11 is attached to the notch 10 of the laminated body 8, and is used to allow blood and dialysate to enter and exit the gasket 11. Two sets of ports 12 are fitted from all sides. One of the two corresponding ports serves as a blood outflow inlet, and the other serves as a dialysate outflow inlet.

4 to 6 show other embodiments of the laminated dialyzer of the present invention. In FIG. 4, side films 2 are arranged on both sides of a large number of fibers 1 in a tube-shaped dialysis membrane 3a. It is housed in a state of confinement. A large number of fibers 1 and side films 2 are arranged in a direction perpendicular to the fibers 1 and side films 2 between the tube-shaped dialysis membrane 3a in which these fibers 1 and side films 2 are placed. In this state, the tubular dialysis membrane 3a in which the fibers 1 and side films 2 are placed and the arrayed layers of the fibers 1 and side films 2 that are not accommodated in the tube-shaped dialysis membrane are alternately stacked. Ru. The tube-shaped dialysis membrane 3a is provided with cutouts 13 at its four corners in a flat state, each having a shape corresponding to the cutouts 4 at both ends of the side film 2.

In FIG. 5, side films 2 are arranged on both sides of a row of a large number of fibers 1, and frame-shaped films 5 as shown in FIG. It is housed in 3a.

In FIG. 6, the arranged side films 2
Cut portions 14 and 14a are provided near one end of each of the fibers and a plurality of respective ends of each fiber, and cut portions 14 and 14a are provided at intervals approximately the same as the fiber spacing, and at both ends of each side film 2a, 2b and the fiber row, the fiber direction is An end side film 15 is arranged in a direction perpendicular to this. In this case, by sealing the end side film 15 and the side film 2b and/or each fiber 1a with a urethane adhesive or the like, the liquid flows as shown by the arrow. The side films 2a, 2b, fibers 1a, and end side films 15 may be arranged between rectangular dialysis membranes as shown in FIG. 1, or as shown in FIG. It may be housed within a tube-shaped dialysis membrane. In addition, the end side film 15
As shown in FIG. 6, notches 16 are provided at both ends of the holder.

Furthermore, above and below each side film 2a, 2b, row of fibers 1a and end side film 15 arranged as described above, sides corresponding to the side length of this arrangement shape are added. A long frame-shaped film 5 may be placed between the rectangular dialysis membranes as shown in FIG.
As shown in the figure, it may be housed in a tube-shaped dialysis membrane. By providing a large number of micropores on the outer edges of the frame film 5, side films 2a, 2b, and end side films 15 arranged as described above, a sealing agent such as urethane adhesive can penetrate. It is preferable because it is easy to insert and sealing performance is improved. This is the second
Of course, the present invention can also be applied to the configuration shown in the figure.

[Effect of idea]

As described above, the stacked dialyzer according to the present invention has a structure in which a large number of fibers are arranged in parallel at predetermined intervals on the dialysis membrane or in the tube-shaped dialysis membrane, so that it can replace the spacer of conventional products. Because there is no weft thread in the mesh, there is no problem such as increased flow resistance during liquid flow and bubbles coming out, and the gap between the membranes can be made extremely small. As a result, the dialyzer can be made smaller while maintaining high dialysis efficiency.

Furthermore, the structure is such that notches are formed at the four corners of the laminate, and frame-shaped gaskets are attached to these parts, so that liquid leakage can be easily prevented with a simple structure, and at the same time, the laminate can be easily prevented from leaking. It also prevents sideways slipping. In addition, a frame-shaped gasket is attached to the above-mentioned notch, and the ports for blood flow and inflow and outflow and dialysate fluid inflow and outflow are fitted into this gasket, which simplifies the structure of the port and Installation is also easy.

[Brief explanation of drawings]

FIG. 1 is a schematic explanatory diagram showing the structure and arrangement of a spacer of a laminated dialyzer according to the present invention, FIG. 2 is a schematic explanatory diagram showing the structure and arrangement of another aspect of the spacer according to the present invention, FIG. 3 is a schematic explanatory diagram showing the installation mode of the stacked dialyzer according to the present invention, and FIGS. 4 and 5 are the structure and arrangement of other embodiments of the dialysis membrane and spacer of the stacked dialyzer according to the present invention. FIG. 6 is a schematic explanatory diagram showing the structure and arrangement of still another aspect of the spacer according to the present invention. 1, 1a are fibers, 2, 2a, 2b are side films, 3, 3a are dialysis membranes, 4, 6, 7, 13, 16
is a notch, 5 is a frame-shaped film, 8 is a laminate, 10
is the notch, 11 is the gasket, 12 is the port, 1
Reference numerals 4 and 14a indicate a cutout portion, and 15 indicates an end side film.

Claims (1)

[Scope of Claim for Utility Model Registration] (1) On a flat, rectangular dialysis membrane with notches at the four corners, or in a tube-shaped dialysis membrane with notches at the four corners in a flat state, one side of the dialysis membrane. A large number of fibers with a length corresponding to the length of the fibers are arranged in parallel at a predetermined interval, and the dialysis membrane edge portions on both sides of the fiber row have a length equivalent to the length of the fibers, and A strip-like side film having a thickness similar to the diameter of the fibers and having notches at both ends of the same long side is moved outward so that the notches correspond to the notches in the dialysis membrane. The laminates are stacked alternately in each layer or in such a way that the direction of fiber arrangement within each tube and between the tubes is perpendicular, and a frame-shaped packing is placed in the notch of the resulting laminate. A laminated dialyzer characterized in that the dialyzer is installed and a port is fitted into the gasket. (2) Between the fiber row and the side films on both sides thereof and the dialysis membrane, there should be a side length corresponding to the side length of the dialysis membrane, and notches provided at the four corners of the dialysis membrane and at both ends of the side films. The dialyzer according to claim 1, which is a utility model, and comprises a frame-shaped film having correspondingly shaped notches at the four corners. (3) Provide cutting sections at approximately the same intervals as the fiber spacing on one side of the arranged side film and near both ends of each of the plurality of fibers, and at both ends of each side film and fiber row in the fiber direction. The dialyzer according to claim 1, which is a registered utility model, comprising an end side film having notches at both ends in a direction perpendicular to . (4) Each of the arranged side films, fiber rows, and end side films has side lengths above and below that correspond to the side lengths of this arrangement shape, and a shape that corresponds to the notches at the four corners of this arrangement shape. The dialyzer according to claim 3 of the utility model registration, comprising a frame-shaped film having four notches at the four corners. (5) The dialyzer according to claim 4 of the utility model registration, which comprises a frame-shaped film, a side film, and an end side film, each of which has a large number of micropores on its outer side.