JPH02311404A - Germicide composition for industry - Google Patents

Abstract

PURPOSE:To obtain the synergistic subject composition containing PARACLOX and DBNPA or DDO as active ingredients and especially used in drain system. CONSTITUTION:The germicidal composition containing 4-hydroxyphenyl-alpha- ketoacetohydroxium acid chloride (PARACLOX) expressed by the formula, dibromonitorylopropionic amide(DBNPA) or 4,5-dichloro-1,2-dithiol-3-one(DDO) at a weight ratio of 9:1 to 1:9. The composition containing 5 to 25wt.% active ingredients in final composition containing a solvent and the dispersed agent is added to water system to be treated in an amount of 2 to 400ppm (2 to 20ppm, in circulating water for paper making).

Description

DETAILED DESCRIPTION OF THE INVENTION Field of the Invention The present invention relates to synergistic disinfectant compositions for use in industry, particularly in industrial and wastewater systems.

[Conventional technology]

Traditionally, industrial cooling water, water used in the manufacture of pulp and paper, so-called process water, and wastewater systems have been attacked by microorganisms such as various bacteria, molds, and yeasts, resulting in damage to heat exchangers. This is causing problems such as blockages and paper cuts. A number of biocides, particularly non-metallic organic biocides, are used to control microbial infestation of these drainage systems.

For example, Japanese Patent Publications No. 52-14294, No. 53-5375, and No. 62-23721;
No. 1-82723, No. 54-132230, No. 54-
No. 135223, No. 60-1105 and No. 61-9
Each publication of No. 1108 discloses various slime control agents, antimicrobials, industrial disinfectants, compositions containing two or more of these, and slime control methods for drainage systems using them. Although the chemicals used for these have their advantages and disadvantages, they are safe, toxic, foaming, pH-dependent, corrosive, water-soluble, stable, cost-effective,
Because it has some drawbacks regarding the sustainability of the effect, etc.
A satisfactory industrial disinfectant remains undeveloped.

[Problem that the invention seeks to solve]

When we searched for a safe, stable, and long-lasting disinfectant composition that is highly effective for industrial wastewater systems, we found that a specific two-component composition showed remarkable synergistic effects over a wide range of two-component combinations. They discovered that it exhibits a bactericidal effect and completed the present invention.

[Means for solving problems]

The industrial fungicidal composition of the present invention comprises 4-hydroxyphenyl-α-ketoacetohydroxyum acid chloride (PARACLO) represented by
X) and dibromnitrilopropionamide (D B N
P A) or 4,5-dichlor-1,2-diothyl-3-one (D DO) as an active ingredient, and the water-based sterilization method is PARACLOX and D
It is constructed by applying a disinfectant composition containing BNPA or DDO as an active ingredient to the aqueous system.

The composition of the present invention requires a relatively large amount to be added to obtain a satisfactory bactericidal effect when used alone, but when both are combined, it exhibits a bactericidal effect with a significantly small amount and has a wide range of effects. Effective in killing harmful microorganisms.

The composition of the invention is used in liquid form. Preferably a hydrophilic organic solvent that provides a storage stable composition is used to dissolve the active ingredient. Examples of such solvents are amides such as dimethylformamide, glycols such as ethylene glycol, propylene glycol, butyl glycol, polyethylene glycol, glycol ethers such as diethylene glycol monomethyl ether or ethylene glycol butyl ether, preferably molecules of polyethylene glycol of the order of ji200. Good.

When the composition of PARACLOX and DDO is used in an aqueous system, the addition of a dispersant is necessary to facilitate and improve the distribution of the composition into the system.

Suitable dispersants are cationic, anionic, nonionic or amphoteric surfactants, particularly preferably nonionic and anionic surfactants. An example of a suitable nonionic activator is the higher alcohol ethylene oxide (E
O)-adducts, alkylphenol E〇-adducts, propylene oxide-EO adducts, and polyglycol ethers and/or esters. Examples of anionic surfactants are alkylbenzene sulfonates, secondary alkanesulfonates, olefin sulfonates, fatty alcohol sulfates and fatty alcohol ether sulfates.

The blending ratio of active ingredients in the composition of the present invention is PARACL
Good effects were obtained when the weight ratio of OX:DBNPA and PARACLOX:DDO was within the range of 9:1 to 1 to 9.

The content of active ingredient in the final composition, including solvents and dispersants, is about 5-25% by weight, but contents up to about 50% by weight are possible.

The composition of the present invention can be added to the aqueous system to be treated in an amount of about 2 to 400 pp.
It is generally added in an amount of 2 to 20 m for papermaking circulating water.
An addition amount of ppm is sufficient.

The present invention will be explained in more detail with reference to Examples below.
These do not limit the scope of the present invention in any way.

[Example 1] 20% weight polyethylene glycol 200 of 4-hydroxyphenyl-α-ketoacetohydroxyum acid chloride (PARACLOX), 20% weight polyethylene glycol 200 of dibromnitrilopropionamide (DBNPA) and a mixing ratio of both 9:1 to 1
Polyethylene glycol 200 with an active ingredient concentration of 20% by weight was prepared according to the following method.

When used, it was diluted with water and used as is.

Next, in order to test the bactericidal effect against harmful microorganisms during the paper manufacturing process, microbial deposits collected from a papermaking system that produces high-quality paper were planted in a modified Waxman medium.
After culturing at 2°C for 4 days, three types of bacteria considered to be the preferential bacterial species were selected based on the color and shape of the colonies, and a bactericidal test was performed using the bacterial liquid that was further cultured in a broth liquid medium.

To identify the bacterial species, various physiological tests were performed to identify S, T, and Co.
It was identified according to the classification table of wan. These are Ffl avocados commonly found in the papermaking process.
ium, Pseudomonas, Al cap i
It was genes.

A pre-cultured bacterial solution was taken in sterile white water, a predetermined amount of the sterilizing composition was added thereto, and after shaking at 32°C for 30 minutes,
A modified Waxman medium was inoculated, and the concentration at which the total number of bacteria in the culture solution became zero at 32° C. for 4 days was determined, and this was determined as the minimum bactericidal concentration. The results are shown in Table-1.

Bacterial species PL:Fj 1vobacteriumPS:
Pseudomonas AL:^J cal igenes As is clear from the above results, PARACLOX and DB
It can be seen that the composition with NPA sterilizes with a significantly smaller amount added than each alone.

[Example 2] 25% weight polyethylene glycol 200 of PARACLOX and 25% weight polyethylene glycol 200 of DDO were blended at a mixing ratio of 9:1 to 1:9, and 10% of polyethylene glycol alkyl Z enol of HLB 14 was added. % weight, active ingredient concentration 20% weight polyethylene glycol 20
0 was prepared.

When used, it was diluted with water and used as is.

Then, using the same method as in Example 1, the bactericidal effect against harmful microorganisms during the paper manufacturing process was tested. However, as a fungicide composition, PARACLOX/DD prepared as above
O composition was used. The results are shown in Table-2.

Table-2 Bacterial species PL:Pj! vobacterlumPs:P
seUdO1fiOnaS AL: ^JeIJIgenes As is clear from the above results, PARACLOX and DD
It can be seen that the composition with O can be sterilized with a significantly smaller amount added than each alone.

〔Effect of the invention〕

Claims (1)

[Claims] 1. 4-hydroxyphenyl-α-ketoacetohydroxyum acid chloride (PARACLO
X) and dibromnitrilopropionamide (DBNPA
) as an active ingredient. 2. The composition according to claim 1, wherein the weight ratio of PARACLOX:DBNPA is in the range of 9:1 to 1:9. 3. 4-Hydroxyphenyl-α-ketoacetohydroxyum acid chloride (PARACLO
X) and 4,5-dichlor-1,2-diothyl-3-
1. An industrial sterilizing composition characterized by containing DDO (DDO) as an active ingredient. 4. The composition according to claim 1, wherein the weight ratio of PARACLOX:DDO is in the range of 9:1 to 1:9. 5. A water-based sterilization method characterized by using the composition according to any one of claims 1 to 4.