JPH0214020B2 - - Google Patents

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Publication number
JPH0214020B2
JPH0214020B2 JP56152308A JP15230881A JPH0214020B2 JP H0214020 B2 JPH0214020 B2 JP H0214020B2 JP 56152308 A JP56152308 A JP 56152308A JP 15230881 A JP15230881 A JP 15230881A JP H0214020 B2 JPH0214020 B2 JP H0214020B2
Authority
JP
Japan
Prior art keywords
days
egg
production
birth
feed composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP56152308A
Other languages
Japanese (ja)
Other versions
JPS5856646A (en
Inventor
Hiroshi Horikawa
Akira Suzuki
Tadahiro Masumura
Michihiro Sugawara
Tatsuo Suda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Itochu Feed Mills Co Ltd
Original Assignee
Itochu Feed Mills Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Itochu Feed Mills Co Ltd filed Critical Itochu Feed Mills Co Ltd
Priority to JP56152308A priority Critical patent/JPS5856646A/en
Publication of JPS5856646A publication Critical patent/JPS5856646A/en
Publication of JPH0214020B2 publication Critical patent/JPH0214020B2/ja
Granted legal-status Critical Current

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  • Feed For Specific Animals (AREA)
  • Fodder In General (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Description

【発明の詳細な説明】[Detailed description of the invention]

この発明は、産卵めんどり用初産促進のための
剤、方法及び飼料組成物に関する。 家禽産業において、産卵量を増加させるるため
の数多くの努力が行なわれ、種々の成果があげら
れている。めんどりは、通常、約150日令〜約160
日令より産卵を開始し、約500日令まで飼養され
る。約500日令以降は、産卵量が低下し、経済的
損失が大きすぎるために飼養を中止する。通常、
約150日令より500日令の期間に、いかに産卵量を
増加させるかの努力が行なわれているが、この期
間での産卵量増加は、ほぼ限界に達したと考えら
れる。いつぽう、育成後期の鶏に飼料を腹いつぱ
い食下させると性成熟が早くなり、初産日令も早
くなることはよく知られている。しかし飼料を制
限しないで飼養した鶏は、体重が増えすぎ、その
結果、卵は早く産み出すが、産卵成積が伸びず、
特に400日令以降の産卵が悪くなる。そこで、育
成期の体重をコントロールすることによつて性成
熟をおさえ、産卵成積の低下を防ぐ方法が一般的
に用いられているが、このような処理をした鶏
は、初産が遅れ、この初期の産卵量の減少が経済
的損失となつている。このように、飼料を制限す
る方法および飽食にする方法は、それぞれ、一長
一短がある。かくて、最も有効な初産促進方法の
関発が待たれていた。 本発明者らは、前記従来技術の問題点を考慮し
て種々検討を加えた結果、飼料を制限し、1α−
ヒドロキシコレカルシフエロール及び/又は1α,
25−ジヒドロキシコレカルシフエロールを有効成
分とする70〜140日令未満の産卵用めんどりの初
産促進剤(以下「初産促進剤」と称する。)を給
与した70〜140日令未満の産卵用鶏は、単に飼料
制限のみ行なつた鶏と比べ、初産が早くなり、な
おかつ、その後の産卵成積は、制限給与した鶏と
同等の成積が得られること、および、飼料を飽食
とし、初産促進剤を給与した70〜140日令未満の
産卵用鶏は単に飼料を飽食とした鶏と比べ、産卵
ピークに早く達し、なおかつ、その後も高産卵が
維持されることを発見し、本発明を完成した。こ
の初産促進剤は、70日〜140日令未満まで給与す
ることができるが120日〜140日令未満までの給与
が最も好ましい。この初産促進剤は、純粋な形
で、または、他の飼料成分と組合せて、結晶の形
で、溶液として、またはけん濁液として、にわと
り飼料配合物に混入させて飼料組成全体に均一に
分布するようにできる。また、植物油等に溶解し
た初産促進剤の経口投与、皮下注射および筋肉注
射によつても同じ効果が得られる。 本発明は、上記従来技術の問題点を解決した産
卵用めんどりの初産促進及び産卵量の増進方法、
初産促進剤及び初産促進用飼料組成物を提供する
ることを目的とする。 本発明によれば、次の産卵用めんどりの初産促
進剤及び産卵量の増進方法、初産促進剤及び初産
促進用飼料組成物により上記目的を達成すること
ができる。 1α−ヒドロキシコレカルシフエロール及
び/又は1α,25−ジヒドロキシコレカルシフ
エロールを有効成分とする70〜140日令未満の
産卵用めんどりの初産促進剤。 1α−ヒドロキシコレカルシフエロール及
び/又は1α,25−ジヒドロキシコレカルシフ
エロールを飼料組成物1Kg当り0.1〜25μgを含
有する70〜140日令未満の産卵用めんどりの初
産促進用飼料組成物。 1α−ヒドロキシコレカルシフエロール及
び/又は1α,25−ジヒドロキシコレカルシフ
エロールをにわとりの70〜140日令未満の期間
投与することを特徴とする産卵用めんどりの初
産促進剤及び産卵量の増進方法。 好ましくは、初産促進剤は経口投与剤又は注射
による投与剤であり、飼料組成物はにわとりの70
〜140日令未満に対応する育成用飼料組成物であ
る。 また、1α−ヒドロキシコレカルシフエロール
及び/又は1α,25−ジヒドロキシコレカルシフ
エロールを1羽1日当り0.01〜2.5μg投与するこ
と、投与は経口投与又は注射による投与により行
なうこと、及び、経口投与をにわとりの70〜140
日令未満に対応する育成用飼料に添加することに
より行うことは、夫々好ましい。初産促進剤の好
適量とは、初産をはやめ、なおかつ、高産卵を維
持させるに必要な最小量である。給与量は、飼料
組成物1Kg当り0.1〜25μgの範囲で使用できる
が、1.5μg〜5.0μgの1α−ヒドロキシコレカルシ
フエロール量が最も好ましい。 1α,25−ジヒドロキシコレカルシフエロール
(1α,25(OH)2D3)は、1α−ヒドロキシコレカル
シフエロール(1αOHD3合成品)を投与した場
合、肝臓内で25位が水酸化され1α,25(OH)2D3
となることが知られているが、この1α,25
(OH)2D3(合成品)を、1αOHD3に代り投与して
も同様の効果が得られる。 なお、鶏1羽当りの1日投与量は凡そ0.01〜
25μg好ましくは0.15〜0.5μgである。 飼料組成物1Kg当り2.5μgの1α−ヒドロキシコ
レカルシフエロール量の給与による初産ならび
に、その後の産卵におよぼす効果は、実施例1に
示したとおりである。なお、飼料組成物を150日
令以降も投与する場合、第1表に示す成鶏用配合
とすることが望ましい。 下記実施例は、この発明を説明するものであつ
て限定するものではない。 実施例 1 市販のビタミンD3を含有する育成用飼料を給
与しているめんどり100羽を4群にわけて、120日
令以降、飽食群と制限群をそれぞれ対照とし、こ
れに1α−ヒドロキシコレカルシフエロール(以
下1αOHD3と略す)を飼料1Kg当り2.5μg添加
し、160日令まで給与した。育成用および成鶏用
飼料組成を第1表に示す。なお、150日令までは
育成用飼料を給与し、これ以降は成鶏用飼料を給
与した。 その結果、1αOHD3給与群は、初産日令が早く
なり、その後の産卵率も未投与群よりも好結果が
得られた。第1図は、飼料を制限した群と、これ
と同処理した群に1αOHD3を給与したときの産卵
成績を示しており、第2図は、飼料を飽食にした
群と、これと同処理した群に1αOHD3を給与した
ときの産卵成績を示している。 その結果、生涯卵生産量は500〜600g増大し、
これは約3〜4%程度の増大となる。即ち、250
日令以降350日令では90%前後、その後も通常通
り500日令では80%程度に産卵率は低下するが、
初産が早くなつた分が生涯卵生産量の増加に寄与
する。
The present invention relates to an agent, method, and feed composition for promoting first birth for egg-laying hens. Many efforts have been made in the poultry industry to increase egg production with varying success. Hens are usually about 150 days old to about 160 days old
They start laying eggs at the age of 1 day and are kept until they are about 500 days old. After about 500 days of age, egg production decreases and the economic loss is too great, so breeding is discontinued. usually,
Efforts are being made to increase the amount of eggs laid between about 150 and 500 days of age, but it is thought that increasing the amount of eggs laid during this period has almost reached its limit. It is well known that if chickens in the later stages of rearing are fed a full diet of feed, they will reach sexual maturity earlier and the age at first production will be earlier. However, chickens raised without food restriction gain too much weight, and as a result, although they produce eggs quickly, the production of eggs does not increase.
Egg-laying becomes particularly poor after 400 days of age. Therefore, a method commonly used is to suppress sexual maturation and prevent a decline in egg production by controlling body weight during the rearing period, but chickens treated in this way delay their first production and suffer from this The reduction in early egg production is an economic loss. As described above, the method of restricting feed and the method of satiation each have advantages and disadvantages. Therefore, the most effective method for promoting first birth has been awaited. The present inventors conducted various studies in consideration of the problems of the prior art, and as a result, they decided to limit feed and 1α-
hydroxycholecalciferol and/or 1α,
A product for egg-laying hens aged 70-140 days that has been fed with a first-birth promoter (hereinafter referred to as "first-birth promoter") containing 25-dihydroxycholecalciferol as an active ingredient. Compared to chickens that are simply fed restricted feed, chickens produce their first egg earlier, and the subsequent production of eggs is equivalent to that of chickens that are fed restricted feed. It was discovered that egg-laying hens aged between 70 and 140 days old that were fed promoters reached their egg production peak earlier than hens that were simply satiated with feed, and that high egg production was maintained thereafter. completed. This first birth promoter can be administered from 70 days to less than 140 days of age, but most preferably from 120 days to less than 140 days of age. The first production promoter can be incorporated into chicken feed formulations in pure form or in combination with other feed ingredients, in crystalline form, as a solution, or as a suspension, to ensure uniform distribution throughout the feed composition. You can do it as you like. The same effect can also be obtained by oral administration, subcutaneous injection, or intramuscular injection of a first birth promoter dissolved in vegetable oil or the like. The present invention provides a method for promoting first production and increasing egg production in egg-laying hens, which solves the problems of the above-mentioned conventional techniques;
The purpose of the present invention is to provide a first production promoting agent and a feed composition for promoting first production. According to the present invention, the above object can be achieved by the following first production promoter for egg-laying hens, method for increasing egg production, first production promoter, and feed composition for promoting first production. A first production promoter for egg-laying hens aged less than 70 to 140 days, containing 1α-hydroxycholecalciferol and/or 1α,25-dihydroxycholecalciferol as an active ingredient. A feed composition for promoting first birth in egg-laying hens less than 70 to 140 days old, containing 0.1 to 25 μg of 1α-hydroxycholecalciferol and/or 1α,25-dihydroxycholecalciferol per 1 kg of the feed composition. An agent for promoting the first production of egg-laying hens and increasing egg production, characterized by administering 1α-hydroxycholecalciferol and/or 1α,25-dihydroxycholecalciferol for a period of less than 70 to 140 days of age of the chicken. Method. Preferably, the first birth promoting agent is an oral or injectable formulation, and the feed composition contains 70% of the chicken feed composition.
This is a feed composition suitable for children under 140 days of age. In addition, 0.01 to 2.5 μg of 1α-hydroxycholecalciferol and/or 1α,25-dihydroxycholecalciferol should be administered per bird per day, and the administration should be carried out orally or by injection; 70-140 chickens
It is preferable to add it to the feed for raising children under 10 days of age. The suitable amount of the first production promoter is the minimum amount necessary to prevent first production and maintain high egg production. The amount of 1α-hydroxycholecalciferol to be fed can range from 0.1 to 25 μg per kg of feed composition, but the most preferred amount is 1.5 μg to 5.0 μg of 1α-hydroxycholecalciferol. When 1α-hydroxycholecalciferol (1αOHD 3 synthetic product) is administered, 1α,25-dihydroxycholecalciferol (1α,25(OH) 2 D 3 ) is hydroxylated at position 25 in the liver and becomes 1α. , 25(OH) 2D3
It is known that this 1α, 25
Similar effects can be obtained by administering (OH) 2 D 3 (synthetic product) instead of 1αOHD 3 . The daily dose per chicken is approximately 0.01~
25 μg, preferably 0.15 to 0.5 μg. The effect of feeding 2.5 μg of 1α-hydroxycholecalciferol per 1 kg of feed composition on first birth and subsequent egg laying is as shown in Example 1. In addition, when administering the feed composition after 150 days of age, it is desirable to use the formulation for adult chickens shown in Table 1. The following examples are intended to illustrate but not limit the invention. Example 1 100 hens fed a commercially available breeding feed containing vitamin D 3 were divided into 4 groups, and after 120 days of age, a satiated group and a restricted group were used as controls, and 1α-hydroxy Cholecalciferol (hereinafter abbreviated as 1αOHD 3 ) was added at 2.5 μg per 1 kg of feed and fed until 160 days of age. The feed composition for rearing and adult chickens is shown in Table 1. In addition, feed for rearing was fed until the age of 150 days, and feed for adult chickens was fed thereafter. As a result, the 1αOHD 3- fed group had an earlier age of first calving, and the subsequent egg production rate was also better than that of the non-fed group. Figure 1 shows the spawning results when 1αOHD 3 was fed to a group with restricted feed and a group treated with the same treatment, and Figure 2 shows the egg production results of a group with restricted feed and a group treated with the same The results show the spawning results when 1αOHD 3 was fed to the same group. As a result, lifetime egg production increases by 500-600g,
This is an increase of about 3 to 4%. i.e. 250
The spawning rate decreases to around 90% at 350 days old, and then to around 80% at 500 days old, as usual.
The earlier first birth contributes to an increase in lifetime egg production.

【表】 ス
[Table]

【表】 実施例 2 にわとり用飼料配合物(育成用)から物理的に
分離し、1日当り1羽のにわとりに0.25μgの
1αOHD3を与えるに充分な1αOHD3を含浸させた
アルフアのような飼料原料(1Kg当り2.5μgの
1αOHD3を含有する)を100日令から140日令にな
るまでにわとりに与えたところ、初産が15日以上
早くなり、その後も高産卵が維続される結果が制
限および飽食群とも認められた。 実施例 3 1日当り約0.25μgの1αOHD3を給与するに充
分量の1αOHD3を、水にけん濁させてにわとり飲
料水に計量して入れた。(なおこの場合1αOHD3
を表面活性剤中に溶解してもよい。)この処理を
行なつた飲料水(1当り1.25μgの1αOHD3
含有する)を100日令から140日令になるまでにわ
とりに飲水給与しても、初産が早くなり、高産卵
が維持される結果が、制限および飽食群とも認め
られた。摂取飲用水の量から推計した投与量は1
羽1日当り0.15〜0.5μgでありこの範囲では有意
差は認められなかつた。 実施列 4 1αOHD3を1日当り0.25μgを給与するに充分
量の1αOHD3を大豆油に溶解し、この溶解液(1
当り1250μgの1αOHD3を含有する)0.2ml以上
を100日令から140日令になるまでにわとりの胸の
皮下に注射した。この処理を行なつても、初産が
早くなり、高産卵が維持される結果が、制限およ
び飽食群とも認められた。
[Table] Example 2 Physically separated from chicken feed formulation (for rearing), 0.25 μg per chicken per day.
Feed ingredients such as alpha impregnated with sufficient 1αOHD 3 to provide 1αOHD 3 (2.5 μg/Kg)
When chickens were given 1αOHD 3 (containing 1αOHD 3) from 100 to 140 days of age, first birth occurred more than 15 days earlier, and high egg production was maintained even after that in both the restricted and satiated groups. . Example 3 Sufficient 1αOHD 3 to provide approximately 0.25 μg of 1αOHD 3 per day was suspended in water and weighed into chicken drinking water. (In this case, 1αOHD 3
may be dissolved in a surfactant. ) If chickens were given this treated drinking water (containing 1.25 μg of 1αOHD 3 per bottle) from 100 to 140 days old, their first birth would be earlier and high egg production would be maintained. Similar results were observed in both the restricted and satiated groups. The dose estimated from the amount of drinking water ingested is 1
The amount was 0.15 to 0.5 μg per feather per day, and no significant difference was observed within this range. Example row 4 Sufficient amount of 1αOHD 3 to administer 0.25 μg of 1αOHD 3 per day was dissolved in soybean oil, and this solution (1
At least 0.2 ml (containing 1250 μg of 1αOHD 3 per chicken) was injected subcutaneously into the breasts of chickens from 100 to 140 days old. Even with this treatment, early first birth and high egg production were observed in both the restricted and satiated groups.

【図面の簡単な説明】[Brief explanation of drawings]

第1図は、実施例において制限給飼群に対する
初産促進剤投与の効果を示す産卵率推移グラフ、
第2図は、実施例において飽食群に対する初産促
進剤投与の効果を示す産卵率推移グラフ、を夫々
示す。
FIG. 1 is an egg-laying rate transition graph showing the effect of administering the first birth promoting agent to the restricted feeding group in the example;
FIG. 2 shows graphs of changes in egg production rate showing the effect of administering the first birth promoting agent to the satiated group in Examples.

Claims (1)

【特許請求の範囲】 1 1α−ヒドロキシコレカルシフエロール及
び/又は1α,25−ジヒドロキシコレカルシフエ
ロールを有効成分とする70〜140日令未満の産卵
用めんどりの初産促進剤。 2 前記初産促進剤は経口投与剤又は注射による
投与剤である特許請求の範囲第1項記載の初産促
進剤。 3 1α−ヒドロキシコレカルシフエロール及
び/又は1α,25−ジヒドロキシコレカルシフエ
ロールを飼料組成物1Kg当り0.1〜25μg含有する
70〜140日令未満の産卵用めんどりの初産促進用
飼料組成物。 4 前記飼料組成物はにわとりの70〜140日令未
満に対応する育成用飼料組成物である特許請求の
範囲第3項記載の飼料組成物。 5 1α−ヒドロキシコレカルシフエロール及
び/又は1α,25−ジヒドロキシコレカルシフエ
ロールをにわとりの70〜140日令未満の期間投与
することを特徴とする産卵用めんどりの初産促進
及び産卵量の増進方法。 6 前記1α−ヒドロキシコレカルシフエロール
及び/又は1α,25−ジヒドロキシコレカルシフ
エロールを1羽1日当り0.01〜2.5μg投与する特
許請求の範囲第5項記載の方法。 7 前記投与は経口投与又は注射による投与によ
り行なう特許請求の範囲第5項又は第6項記載の
方法。 8 前記経口投与をにわとりの70〜140日令未満
に対応する育成用飼料に添加することにより行う
特許請求の範囲第7項記載の方法。
[Scope of Claims] 1. A first production promoter for egg-laying hens aged 70 to 140 days, containing 1α-hydroxycholecalciferol and/or 1α,25-dihydroxycholecalciferol as an active ingredient. 2. The first birth promoting agent according to claim 1, wherein the first birth promoting agent is an oral administration agent or an injection agent. 3 Contains 0.1 to 25 μg of 1α-hydroxycholecalciferol and/or 1α,25-dihydroxycholecalciferol per 1 kg of feed composition.
A feed composition for promoting first birth in egg-laying hens less than 70 to 140 days old. 4. The feed composition according to claim 3, wherein the feed composition is a breeding feed composition for chickens aged 70 to 140 days. 5. Promotion of first production and increase of egg production in egg-laying hens, characterized by administering 1α-hydroxycholecalciferol and/or 1α,25-dihydroxycholecalciferol to chickens for a period of less than 70 to 140 days of age. Method. 6. The method according to claim 5, wherein 0.01 to 2.5 μg of the 1α-hydroxycholecalciferol and/or 1α,25-dihydroxycholecalciferol is administered per bird per day. 7. The method according to claim 5 or 6, wherein the administration is carried out orally or by injection. 8. The method according to claim 7, wherein the oral administration is carried out by adding to breeding feed for chickens aged 70 to 140 days.
JP56152308A 1981-09-26 1981-09-26 Promotion of first egg-laying of laying hen, promotor for first egg-laying and feed composition for it Granted JPS5856646A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP56152308A JPS5856646A (en) 1981-09-26 1981-09-26 Promotion of first egg-laying of laying hen, promotor for first egg-laying and feed composition for it

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56152308A JPS5856646A (en) 1981-09-26 1981-09-26 Promotion of first egg-laying of laying hen, promotor for first egg-laying and feed composition for it

Publications (2)

Publication Number Publication Date
JPS5856646A JPS5856646A (en) 1983-04-04
JPH0214020B2 true JPH0214020B2 (en) 1990-04-05

Family

ID=15537681

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56152308A Granted JPS5856646A (en) 1981-09-26 1981-09-26 Promotion of first egg-laying of laying hen, promotor for first egg-laying and feed composition for it

Country Status (1)

Country Link
JP (1) JPS5856646A (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS50100216A (en) * 1973-01-10 1975-08-08
JPS513979A (en) * 1974-06-10 1976-01-13 Upjohn Co

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS50100216A (en) * 1973-01-10 1975-08-08
JPS513979A (en) * 1974-06-10 1976-01-13 Upjohn Co

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