JPH01500267A - Cosmetics containing hydrogen peroxide and α-bisabolol, and the use of α-bisabolol as a hydrogen peroxide stabilizer - Google Patents

Abstract

(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

[Detailed description of the invention] Hydrogen peroxide and α-bisabolol containing cosmetic side and hydrogen peroxide stabilizer α-Bisabo and 夾夙Benri-------------One aspect of the present invention is hydrogen peroxide and A beauty agent containing α-bisabolol represented by the following formula (1), and α-bisabolol Concerning the use of rolls as hydrogen peroxide stabilizers.

Hydrogen peroxide is used in the beauty field, for example as a skin disinfectant, as an oxidative dye for hair or as a hair dye. is used as a blonding agent and as an oxidative post-treatment agent after reduction processing of hair.

By the way, hydrogen peroxide is a metastable compound and decomposes while generating oxygen. on the other hand , oxygen is very insoluble in water (Bunsen's absorption coefficient is 0.03 at 20°C) ), therefore, an overpressure condition may occur in a closed container, especially when stored for a long time. Ru. As a result, there is a risk that the substance inside the container will spray out. Moreover, due to overpressure, The container may burst, or if a synthetic resin container is used, the container may become deformed or There is even a risk that it will eventually explode.

Therefore, hydrogen peroxide-containing beauty products need to be stabilized against hydrogen peroxide. be.

“Hydrogen Peroxide” by Matthieu, published by Sbringer, pp. 197-208. A large number of stabilizers for hydrogen peroxide have been described, including organic compounds. It is shown. However, the performance of these stabilizers cannot be maintained for a long time. is the reality.

German Patent No. 91.285 (Shi, Rasbe) states that among Thymol, menthol and camphor act as stabilizers for solutions containing hydrogen peroxide It is stated that However, these compounds have an unpleasant pungent odor, It can only be used to a very limited extent for hairdressing agents.

Taking these into consideration, in the present invention, compared to those using known stabilizers, peroxide water is We provide a hydrogen peroxide-containing beauty agent that has excellent stability against chemicals and has no unpleasant odor. I set out with this as my challenge.

And here, α-bisabolol represented by the following formula (1) is compared to hydrogen peroxide. By using it as a stabilizer, the above problems can be solved very well. was discovered.

α-Bisabolol is also one of the tenbels, but its stabilization against hydrogen peroxide Its performance is 5 to 10 times higher than thymol, menthol or camphor. Such characteristics This was completely unforeseeable and was first proven through the comparative test shown in Example 1. It has been clarified.

Furthermore, α-bisabolol has a faintly sweet floral scent, so it is used in beauty products. However, there is no need to worry about the scent.

Furthermore, when using beauty products containing hydrogen peroxide, the skin may become red and swollen. You may feel stinging, but using alpha-bisabolol can help prevent this. It turns out that the situation can be avoided.

That is, the present invention is represented by iM hydrogen hexahydride and -.flu　j,''<　(I　) Cosmetics containing α bizabolol are also covered.

This new beauty agent contains hydrogen peroxide from about 0.5' to about 18! ! ! Burnt 2, and about 0.01 to about 2.5 weight of α-bisabolol! Basen)・Including have

The pH value of the new cosmetic agent is preferably within the range of about 1.5 to 3.5.

In the cosmetic preparation according to the present invention, α-bisabolol is used as the sole stabilizer. However, it is also possible to use them together with already known stabilizers.

Known stabilizers include, for example, alkali hydrogen sulfate, alkali acid phosphate, and metaphosphoric acid. Acid salts of strong acids such as sodium and alkali polyphosphates, or aromatic sulfones Examples include acids. Furthermore, ascorbic acid, g acid, phosphoric acid, pyrophosphoric acid, polyphosphoric acid, salt Acid, paroxylic acid, ammonium, chromatic acid, salicylic acid, malonic acid, citric acid and tannic acid and phenol, thymolbalaformaldehyde, 4-acetamidophenol and zenacetin.

The new cosmetic agent may also contain a surfactant. However, in that case, the interface It is assumed that the hydrophobic portion of the active agent is saturated and cannot be oxidized.

As suitable surfactants, especially a) Anionic surfactants such as lauryl alcohol diglycol ether sulfur sulfuric acid having 12 to 18 carbon atoms, preferably 12 to 14 carbon atoms; lauryl sodium or triethanolamine salt, lauryl or tetra Sodium salt or triethanolate of tradecyl-ether sulfate Min salt, disodium salt of sulfosuccine-containing esters of alkanolamides Alkyl sulfonates, alkyl sulfates and alkyl sulfate ethers, such as metal salts, alkaline earth metal salts, ammonium salts or alkanolamine salts , soaps and polyether carboxylic acids, b) Nonionic surfactants, for example C12-C18 oxyethylated aliphatic alcohol, e.g. 4 ethylene oxide per mole of aliphatic alcohol Lauryl, tetradecyl, cetyl and sulphate oxyethylated at 0 mol or less Thearyl-alcohol alone or a mixture of these, oxyethylated lanolin Aliphatic alcohol, the number of carbon atoms in the alkyl group is 8 to 30, and the number of carbon atoms in the molecule is Polyglycol ether of alkylphenol having a recall unit of 1 to 10 fatty acid alcohol amide, and oxyethylated sorbitan fatty acid ester le, C) Cationic surfactants such as dilauryldimethylammonium chloride , alkyldimethylbenzyl ammonium salt chloride or bromide, alkyl Trimethylammonium salts, such as cetyltrimethylammonium chloride Or bromide, tetradecyltrimethylammonium chloride or Bromide, alkyldimethylhydroxyethylammonium chloride or is bromide, dialkyldimethylammonium chloride or bromide , alkylpyridinium salts such as lauryl or cetylpyridinium salts. loride, alkylamide ethyl trimethylammonium ether sulfate, amino Compounds with cationic properties such as oxides, e.g. alkyldimethylamines oxide or alkylaminoethyldimethylaminooxide and d) Amphoteric surfactants, such as carboxy derivatives of imidazole, N-alkyl - and N-alkylamido-betaine, N-alkylsulfobetaine, N-alkyl Kylaminopropionate, alkyl dimethyl carbon having 12 to 18 carbon atoms Ruboxymethylammonium salts as well as fatty acid alkylamide betaines, e.g. Fatty acid aminopropyl dimethylaminoacetic acid betaine is mentioned.

In order to enhance the effect of hydrogen peroxide-containing oxidizing agents for hair treatment, swelling agents and Penetrants such as urea, 2-pyrrolidone, 1-methyl-2-pyrrolidone and di- Propylene glycol monomethyl ether can be added.

It is obvious that the beauty agent according to the present invention has the following benefits in addition to the above. Known additives commonly used, such as kaolin, bentonite, fatty acids, Higher aliphatic alcohols, starch, polyacrylic acid, cellulose derivatives, algines Thickeners such as petrolatum, petrolatum or paraffin oil, or dyes, polyethylene Opacifying agents such as glycol esters, as well as ethanol, propatool or Alcohols such as isopropanol, solvents, stabilizers, buffers, perfume oils or lanolin hair conditioning agents such as derivatives, cholesterin or betaine; contains a protective agent. The components mentioned above are commonly used for their respective purposes. Used in the amount available. For example, the thickener may be about 0.1 to 25 parts by weight. cents used.

Furthermore, this new beauty agent can be squeezed, filled into a spray container, and taken out as a foam. It can also be applied in this form.

The cosmetic agent according to the present invention can be used as a chemical agent especially when dyeing hair, or as a hair reducing agent. Useful as an oxidative post-treatment agent.

For hair dyeing, the novel oxidizing agent is mixed with the dye-containing medium immediately before use.

Apply a suitable amount of this mixture on the hair. About 10 at about 15 to 50℃ After 45 minutes of treatment, rinse with water, sulfurize, dry the hair, and dry the hair as necessary. Rinse with a benign organic acid, such as citric or tartaric acid.

For hair processing, the hair is first treated with a reducing agent such as an alkali mercaptocarboxylate. treatment with a water-retaining solution, for example using curlers or by combing. to the desired shape. After sufficient action time, wash the hair with water and then apply the new Treat with oxidizing agent, rinse again with water and centrate if necessary.

Next, the present invention will be explained in more detail with reference to Examples.

ゑSeeing stem dog Kogyo Tai Boiling Ministry Example 1: Oxidizing agent for hair dyeing or bleaching PH value -2.1 α-Bisabolol 0.5g 50% aqueous solution of hydrogen peroxide 12.0g Cetylstearyl alcohol 2.0g Wool wax 1.0g Sodium lauryl sulfate 0.5g 2-octyl-decanol 0.5g With 10 moles of ethylene oxide Oxyethylated nonylphenol 1.0g Perfume oil 0.2g 85% aqueous solution of 0-phosphoric acid 0.1g Water (completely desalinated) - "Yu?" ■−11 100.0g For comparison, in the drug (1) above, α・-bisabolol was added to the same amount of thymol. (la), replaced with menthol (1b) and camphor (lc), and completely A sample (1d) without the stabilizer was prepared.

These comparison agents were incubated at 40°C for 3 months and at 30°C for 6 months, respectively. When stored for a while, the same results were obtained for each. These results are shown below It is shown in Table 1.

Table 1 − = No overpressure condition 10 - Overpressure condition +10-high overpressure condition Hydrogen peroxide loss is determined by thioglytic acid/iodine titration.

The above comparative tests show that α-bisabolol is more effective than thymol, menthol and camphor. It can be seen that the stabilization against hydrogen peroxide is substantially superior.

Example 2: Oxidation post-treatment agent after reduction permanent processing, PH value -2.5 Sodium lauryl ether sulfate (oxyethylated with 2 moles of ethylene oxide per 1 mole of lauryl alcohol) 6.0g α-Bisabolol 0.1g 50% aqueous solution of hydrogen peroxide 5.0g Hippuric acid 0.1g Nonylphenol (oxyethylated with 10 moles of ethylene oxide > 1.0 g Citric acid 1.0g Water (completely desalinated) F36.8L---.

100.0g No overpressure conditions were observed even after storage for 3 to 6 months.

Example 3: Oxidation post-treatment agent after reduction permanent processing, PH value = 2.8 α-Bisabolol 0.01g 50% aqueous solution of hydrogen peroxide 4. OOg fatty acid amidoprobyl dimethylamino 30% water with fermented acid betaine? Liquid 2.00g lauryl dimethylamino oxide 0.50g ethylenediaminetetraacetic acid n O, 20g0g zenacetin 0. 05g Sodium dihydrogen phosphate 0.20g Water (completely desalinated) 93.001 100.00g No overpressure conditions were observed even after storage for 3 to 6 months.

Example 4: Oxidizing agent for hair dyeing or bleaching PH value -2.2 α-Bisabolol 2.5g 50% aqueous solution of hydrogen peroxide 24. h Nonylphenol (oxyethylated with 10 moles of ethylene oxide) 3.0 g 〇-85% aqueous solution of phosphoric acid 0.1g Water (completely desalinated) 70.4 100.0g No overpressure conditions were observed even after storage for 3 to 6 months.

Example 5: Oxidation post-treatment agent after reduction de-perming processing PH=2.5 α-Bisabolol 0.5g i! ! 50% aqueous solution of hydrogen pentoxide 4.0g coconut fatty acid monoethanolamine 2.0g lauryl alcohol-diglycol Sodium salt of ether sulfate 28% aqueous solution 10.0g Perfume oil 0.5g Water (completely desalinated) - First Deputy Superintendent [- 100,0g No overpressure conditions were observed even after storage for 3 to 6 months.

In this application, percentages refer to weight percentages unless otherwise indicated. .

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Claims (5)

[Claims] 1. A beauty agent characterized by containing hydrogen peroxide and α-bisaporol. 2. It is characterized by containing 0.5 to 18% by weight of hydrogen peroxide. A cosmetic agent according to claim 1. 3. Contains 0.01 to 2.5 weight percent of α-bisaporol. The beauty agent according to claims 1 and 2, characterized by: 4. Claim 1, characterized in that the pH value is 1.5 to 3.5. The beauty agent according to item 3. 5. Use of α-bisaporol for stabilizing hydrogen peroxide.