JPH01230510A - Agent for etching - Google Patents
Agent for etchingInfo
- Publication number
- JPH01230510A JPH01230510A JP63058084A JP5808488A JPH01230510A JP H01230510 A JPH01230510 A JP H01230510A JP 63058084 A JP63058084 A JP 63058084A JP 5808488 A JP5808488 A JP 5808488A JP H01230510 A JPH01230510 A JP H01230510A
- Authority
- JP
- Japan
- Prior art keywords
- etching
- salt
- agent
- dtpa
- dentin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000005530 etching Methods 0.000 title claims abstract description 37
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 20
- -1 diethylenetriaminepentaacetic acid metal complex amine salt Chemical class 0.000 claims abstract description 19
- 229960003330 pentetic acid Drugs 0.000 claims abstract description 15
- QPCDCPDFJACHGM-UHFFFAOYSA-N N,N-bis{2-[bis(carboxymethyl)amino]ethyl}glycine Chemical class OC(=O)CN(CC(O)=O)CCN(CC(=O)O)CCN(CC(O)=O)CC(O)=O QPCDCPDFJACHGM-UHFFFAOYSA-N 0.000 claims abstract description 9
- 210000004268 dentin Anatomy 0.000 abstract description 16
- 210000003298 dental enamel Anatomy 0.000 abstract description 9
- 230000000694 effects Effects 0.000 abstract description 7
- 229910052783 alkali metal Inorganic materials 0.000 abstract description 6
- 150000003863 ammonium salts Chemical class 0.000 abstract description 4
- 210000003074 dental pulp Anatomy 0.000 abstract description 4
- 229910021578 Iron(III) chloride Inorganic materials 0.000 abstract description 2
- RBTARNINKXHZNM-UHFFFAOYSA-K iron trichloride Chemical compound Cl[Fe](Cl)Cl RBTARNINKXHZNM-UHFFFAOYSA-K 0.000 abstract description 2
- ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical class CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 abstract 1
- 230000001070 adhesive effect Effects 0.000 description 19
- 239000000853 adhesive Substances 0.000 description 18
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 13
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 12
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 8
- 239000007864 aqueous solution Substances 0.000 description 7
- 238000000034 method Methods 0.000 description 7
- 239000000243 solution Substances 0.000 description 7
- 238000005115 demineralization Methods 0.000 description 6
- 230000002328 demineralizing effect Effects 0.000 description 6
- VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical compound COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 description 5
- 239000012153 distilled water Substances 0.000 description 5
- 239000000203 mixture Substances 0.000 description 5
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 5
- 239000004926 polymethyl methacrylate Substances 0.000 description 5
- 239000000843 powder Substances 0.000 description 5
- RMCCONIRBZIDTH-UHFFFAOYSA-N 2-(2-methylprop-2-enoyloxy)ethyl 1,3-dioxo-2-benzofuran-5-carboxylate Chemical compound CC(=C)C(=O)OCCOC(=O)C1=CC=C2C(=O)OC(=O)C2=C1 RMCCONIRBZIDTH-UHFFFAOYSA-N 0.000 description 4
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical group OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 4
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 4
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 4
- 239000000178 monomer Substances 0.000 description 4
- 239000002253 acid Substances 0.000 description 3
- 239000000654 additive Substances 0.000 description 3
- 230000000996 additive effect Effects 0.000 description 3
- UMEAURNTRYCPNR-UHFFFAOYSA-N azane;iron(2+) Chemical compound N.[Fe+2] UMEAURNTRYCPNR-UHFFFAOYSA-N 0.000 description 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- 208000002599 Smear Layer Diseases 0.000 description 2
- OOIOHEBTXPTBBE-UHFFFAOYSA-N [Na].[Fe] Chemical compound [Na].[Fe] OOIOHEBTXPTBBE-UHFFFAOYSA-N 0.000 description 2
- 230000002950 deficient Effects 0.000 description 2
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 2
- 239000010931 gold Substances 0.000 description 2
- 229910052737 gold Inorganic materials 0.000 description 2
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 description 2
- 238000002203 pretreatment Methods 0.000 description 2
- 238000004381 surface treatment Methods 0.000 description 2
- QCUCAQZMPVIYAJ-UHFFFAOYSA-N 2-(4-methyl-1h-indol-3-yl)ethanamine Chemical compound CC1=CC=CC2=C1C(CCN)=CN2 QCUCAQZMPVIYAJ-UHFFFAOYSA-N 0.000 description 1
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 238000004873 anchoring Methods 0.000 description 1
- 208000002925 dental caries Diseases 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 235000019253 formic acid Nutrition 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 150000007522 mineralic acids Chemical class 0.000 description 1
- 210000000214 mouth Anatomy 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 239000005416 organic matter Substances 0.000 description 1
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
Abstract
Description
【発明の詳細な説明】
産業上の利用分野
この発明はムシ歯治療を目的とした処置をするときに行
なわれる歯牙の表面処理、或いは、ムシ歯その他の理由
で欠損を生じた歯牙の修復に際し行なわれる歯牙の表面
処理に適した前処理剤組成物を提供するにある。従って
、歯科医療分野で利用される。[Detailed Description of the Invention] Industrial Field of Use This invention is applicable to surface treatment of teeth performed during treatment for the purpose of treating cavities, or when restoring teeth that have become defective due to cavities or other reasons. An object of the present invention is to provide a pretreatment agent composition suitable for surface treatment of teeth. Therefore, it is used in the dental medical field.
（従来の技術）
湿潤状態にある口腔内で、欠損を生じた歯牙を修復する
とき、歯牙と材料とを接着性組成物により。(Prior Art) When repairing a defective tooth in a moist oral cavity, the tooth and material are bonded together using an adhesive composition.
接着して、より強固にくっつけるため、被着面を前処理
することが行なわれている。この前処理によって、歯牙
表面に微細な凹凸構造をつくり、接着面積を拡げるとと
もに、機械的な嵌合や投錨効果を求めることができる。In order to bond more firmly, the surface to which it is attached is pretreated. Through this pretreatment, it is possible to create a fine uneven structure on the tooth surface, expand the bonding area, and obtain mechanical fitting and anchoring effects.
ここにおいて採られている前処理方法に、酸エツチング
法がある。使用されるものとして、リン酸、塩酸などの
無機酸、ギ酸、クエン酸、などの有機酸があげられる。The pretreatment method employed here is an acid etching method. Those used include inorganic acids such as phosphoric acid and hydrochloric acid, and organic acids such as formic acid and citric acid.
これらはいづれも歯牙面の脱灰に関与すると考えられて
いる。脱灰能、接着性向上においてリン酸が最も優れて
おり、多用されている。しかしながら、リン酸を代表と
する酸エツチング法は、エナメル質に対する接着強度に
は著しく寄与したが象牙質への接着については効果乏し
く、未だ探索の段階である。All of these are thought to be involved in demineralization of tooth surfaces. Phosphoric acid has the best demineralization ability and adhesive properties, and is widely used. However, although acid etching methods, typically using phosphoric acid, have significantly contributed to the strength of adhesion to enamel, they have little effect on adhesion to dentin, and are still at the exploration stage.
（発明が解決しようとする問題点）
接着という手段で歯牙を修復するとき或いはムシ歯の進
行を予防するときエナメル質であると象牙質であるとを
問わず接着強度を高めるためにエツチングと称する前処
理を施すが、エナメル質部分での二°ツチングに用いら
れるエツチング剤を象牙質にそのまま適用することは象
牙質が有機物に富んだ層であることと、核層は歯髄に近
いため、それへの影響が憂慮されていることなどからみ
て、種々の問題を引き起こす。(Problems to be Solved by the Invention) When restoring teeth by means of adhesion or preventing the progression of tooth decay, etching is used to increase the adhesive strength, regardless of whether it is to enamel or dentin. Pretreatment is performed, but applying the etching agent used for double-etching the enamel directly to the dentin is difficult because dentin is a layer rich in organic matter and the nuclear layer is close to the pulp. This poses various problems, as there are concerns about its impact on
しかし、象牙質への接着を強固にするためにはスメア層
の除去を行なうことが必要であると考えられており、既
に象牙質用の前処理剤が市販されている。それら市販品
はクエン酸を主成分とするもの、エチレンジアミン四酢
酸（ＥＤＴＡ）を主成分とするものなどである。しかし
、クエン酸はエナメル質の前処理に使用されるリン酸に
次ぐ強いエツチング剤であるので歯髄への作用が憂慮さ
れるところである。However, it is considered necessary to remove the smear layer in order to strengthen the adhesion to dentin, and pretreatment agents for dentin are already commercially available. These commercially available products include those whose main component is citric acid and those whose main component is ethylenediaminetetraacetic acid (EDTA). However, since citric acid is the second strongest etching agent after phosphoric acid used for pre-treatment of enamel, there are concerns about its effect on the dental pulp.
歯髄に対し安全でしかもスメア層の除去に効果があると
されているＥＤＴＡを主成分とする前処理剤は多少効果
の点において弱いとされている。Pretreatment agents containing EDTA as a main component, which are said to be safe for the dental pulp and effective in removing the smear layer, are said to be somewhat weak in effectiveness.
本発明者らは特開昭６１−１８３２０３においてＥＤＴ
Ａまたはそのアルカリ金属塩とＥＤＴＡ金属錯塩とを組
み合わせることによって象牙質の好適なエツチング剤と
しての使用が可能となることを見出しだが、更にこの系
の発展を考え短時間にしかも好ましい作用機能を保持し
つつ弱点とされている点の改善に成功した。加えて、単
に象牙質のみならずエナメル質のエツチング剤としても
、多用されているエツチング剤と同等の効果を発揮する
ことが判った。The present inventors published the EDT in Japanese Patent Application Laid-Open No. 61-183203
It was discovered that by combining A or its alkali metal salt with EDTA metal complex salt, it can be used as a suitable etching agent for dentin, and considering the further development of this system, it is possible to maintain a favorable action function in a short time. However, we succeeded in improving the points that were considered weak points. In addition, it has been found that the etching agent not only dentin but also enamel has the same effect as commonly used etching agents.
（問題点を解決するための手段）
本発明によって提供される歯牙象牙質のエツチング剤は
ジエチレントリアミン五酢酸（ＤＴＰＡ）アミン塩、Ｄ
ＴＰＡアルカリ金属塩、ＤＴＰＡ金Ｊｊｌ錯体アミン塩
、ＤＴＰＡ金属錯体アルカリ金属塩から選ばれる一種又
は二種以上を含んでなる。(Means for Solving the Problems) The tooth dentin etching agent provided by the present invention is diethylenetriaminepentaacetic acid (DTPA) amine salt, D
It contains one or more selected from TPA alkali metal salt, DTPA gold complex amine salt, and DTPA metal complex alkali metal salt.
ここにおいてＤＴＰＡアミン塩とはＤＴＰＡアンモニウ
ム塩、ＤＴＰＡトリエチルアミン塩、ＤＴＰＡトリエタ
ノールアミン塩、ＤＴＰＡアルカリ金属塩とはＤＴＰＡ
ナトリウム塩、ＤＴＰＡカリウム塩などを相称し、ＤＴ
ＰＡ金Ｘ錯体とは上記ＤＴＰＡアミン或いはアルカリ金
属塩の金属（例えば、鉄、コバルト、マンガン、カルシ
ウム、銅など）錯体を相称する。Here, DTPA amine salt means DTPA ammonium salt, DTPA triethylamine salt, DTPA triethanolamine salt, and DTPA alkali metal salt means DTPA.
Commonly known as sodium salt, DTPA potassium salt, etc., DT
The PA gold
これらは通常水溶液として用いる。濃度は特に限定され
る訳ではないが０．１〜１．０モル濃度で良い。These are usually used as aqueous solutions. Although the concentration is not particularly limited, it may be 0.1 to 1.0 molar concentration.
（発明の効果）
本発明によって提供される組成物は、はぼ中性であり、
これを象牙質のエツチング剤に使用すると非常に短時間
に、しかも、１０％クエン酸−３％塩化第二鉄（１０−
３：現在象牙質のエツチング剤として使用されている。(Effects of the invention) The composition provided by the present invention is substantially neutral,
When this is used as a dentin etching agent, it can be used in a very short time, and moreover, it can be used as an etching agent for dentin (10% citric acid - 3% ferric chloride (10-
3: Currently used as an etching agent for dentin.
）にてエツチングしたときに得られる接着強度と同等の
結果がえられるうえに、（１０−３）では憂慮される歯
髄への影響を心配しなくてもよく、更に（１０−３）や
リン酸に比較して脱灰量が少なく歯牙へ与える損傷を減
らせることも従来技術に較べ本発明の利点といえる。本
発明によって提供される組成物は、エナメル質のエツチ
ング剤として使用しても治療上十分な接着強度が得られ
る。), it is possible to obtain results equivalent to the adhesive strength obtained when etching with (10-3), and there is no need to worry about the effect on the dental pulp, which is a concern with (10-3). Another advantage of the present invention over the prior art is that the amount of demineralization is smaller than with acids, and damage to teeth can be reduced. The composition provided by the present invention can provide therapeutically sufficient adhesive strength even when used as an enamel etching agent.
以下本発明を具体的に説明するために実施例を記述する
。Examples will be described below to specifically explain the present invention.
実施例１
０．５Ｍ ＤＴＰＡ２７’ｚモ＝ウム塩と０．５ＭＤ
ＴＰＡ鉄ナトリウム塩とを１：４の比で混合し均一な水
溶液を得た（ｐＨ７，４とする）。↑；）られた溶液４
０μｍで、エメリペーパー＃６００で研削した生歯の象
牙質部を６０秒間エツチング処理じたのち、蒸溜水でよ
く洗浄し、気銃で表面に付着した水分を除去し、被着面
とした。添加モノマーとして４−ＭＥＴＡを２％含むメ
チルメタクリレートにＴＢＢを添加し、筆積法にてポリ
メチルメタクリレート粉末とともに被着面にとり、直系
５．００ｍｍのアクリル棒を被着面に垂直に立て、３０
分間静置し３７℃の水中に１０浸漬したのち接着強度を
測定した。Example 1 0.5M DTPA27'zMo salt and 0.5MD
TPA iron sodium salt was mixed at a ratio of 1:4 to obtain a homogeneous aqueous solution (pH 7.4). ↑;) solution 4
After etching the dentin of a natural tooth ground with Emery Paper #600 to 0 μm for 60 seconds, it was thoroughly washed with distilled water, and the water adhering to the surface was removed using an air gun to provide an adhesion surface. TBB was added to methyl methacrylate containing 2% of 4-META as an additive monomer, and it was placed on the adherend surface along with polymethyl methacrylate powder using the brush stroke method.
After standing for a minute and immersed in water at 37°C for 10 minutes, the adhesive strength was measured.
エツチング 脱灰量 接着強度（ｓｅａ）
（μｇ／ａｍ”） （ＭＰａ）６０ ３
２．０±３．０ １３．８±１．１実施例２
実施例１で用いたと同じ種類のエツチング液（混合比２
： ３）（ＰＨ７，４とする）を同量使ったほかは実
施例１と同じにして接着強度を測定した。Etching Demineralization amount Adhesive strength (sea)
(μg/am”) (MPa)60 3
2.0±3.0 13.8±1.1 Example 2 The same type of etching solution used in Example 1 (mixing ratio 2
The adhesive strength was measured in the same manner as in Example 1 except that the same amount of 3) (pH 7.4) was used.
エツチング 脱灰量 接着強度（ｓｅｃ）
（μｇ／Ｃｍ”） （ＭＰａ）６０ ２
１．３±１．３ １３．１±５．６実施例３
０．５Ｍ（７）ＤＴｒ’Ａｉアンモニウム塩水溶液（ｐ
Ｈ７，４とする）だけをエツチング液として使用した外
は実施例１と同じにして接着強度を測定した。Etching Deashing amount Adhesive strength (sec)
(μg/Cm”) (MPa)60 2
1.3±1.3 13.1±5.6 Example 3 0.5M (7) DTr'Ai ammonium salt aqueous solution (p
The adhesive strength was measured in the same manner as in Example 1 except that only H7.4) was used as the etching solution.
エツチング 脱灰な 接着強度（ｓｅｅ）
（μｇ／ｃｍ”） （ＭＩ’ａ）６０
１３．７±１．５１４．．２±６．３実施例４
０．５Ｍ ＤＴＰＡ２アンモニウム塩とＱ、５ＭＤＴ
ＰＡ鉄アンモニウム塩とを１：４の比で混合し均一な水
溶液を得た（ｐ）４７．４とする）。Etching Deashing Adhesive strength (see)
(μg/cm”) (MI'a)60
13.7±1.514. ．． 2±6.3 Example 4 0.5M DTPA2 ammonium salt and Q, 5MDT
PA and iron ammonium salt were mixed at a ratio of 1:4 to obtain a homogeneous aqueous solution (p=47.4).
得られた溶液４０μｌで、エメリペーパー＃６００で研
削した生歯の象牙質部を６０秒間エツチング処理したの
ち、蒸溜水でよく洗浄し、気銃で表面に付着した水分を
除去し、被着面とした。添加モノマーとして４−ＭＥＴ
Ａを２％含むメチルメタクリレートにＴｌ３ｒ３を添加
し、下積法にてポリメチルメタクリレート粉末とともに
被着面にとり、直系５．００ｍｍのアクリル捧を被着面
に垂直に立て、３０分間静置し３７℃の水中に１０浸漬
したのち接着強度を測定した。Etch the dentin of a raw tooth ground with Emery Paper #600 for 60 seconds with 40 μl of the resulting solution, wash well with distilled water, remove moisture adhering to the surface with an air gun, and remove the attached surface. And so. 4-MET as added monomer
Tl3r3 was added to methyl methacrylate containing 2% A, and it was placed on the surface to be adhered together with polymethyl methacrylate powder using the underlay method, and an acrylic rod with a diameter of 5.00 mm was stood perpendicularly to the surface to be adhered, and left to stand for 30 minutes. The adhesive strength was measured after immersion in water at a temperature of 10°C for 10 minutes.
エツチング 脱灰量 接着強度（ｓｅｅ）
（／ｊｇ／ａｍ”） （ＭＰａ）６０
２１．３±１．３ １２．７±３．２実施例５
０．５Ｍ ＤＴＰＡ２アンモニウム塩と０．５ＭＤＴ
ＰＡ鉄アンモニウム塩とを３：２の比で混合し均一な水
溶液を得た（ｐＨ７，４とする）。Etching Demineralization amount Adhesive strength (see)
(/jg/am”) (MPa)60
21.3±1.3 12.7±3.2 Example 5 0.5M DTPA2 ammonium salt and 0.5MDT
PA and iron ammonium salt were mixed at a ratio of 3:2 to obtain a homogeneous aqueous solution (pH 7.4).
得られた溶液４０μｍで、生歯のエナメル質面を１０秒
間、３０秒間エツチング処理したのち、蒸溜水でよく洗
浄し、気銃で表面に付着した水分を除去し、被着面とし
た。添加モノマーとして４−ＭＥＴＡを２％含むメチル
メタクリレートにＴＢＢを添加し、下積法にてポリメチ
ルメタクリレート粉末とともに被着面にとり、直系５．
００ｍｍのアクリル棒を被着面に垂直に立て、３０分間
静置し３７℃の水中に１日浸漬したのち接着強度を測定
した。The enamel surface of the natural tooth was etched for 10 seconds and 30 seconds using the obtained solution at 40 μm, then thoroughly washed with distilled water, and the water adhering to the surface was removed using an air gun to obtain an adhesion surface. TBB was added to methyl methacrylate containing 2% of 4-META as an additive monomer, and the mixture was placed on the adhering surface together with polymethyl methacrylate powder using the sublayer method, and a straight line 5.
A 00 mm acrylic rod was placed vertically on the surface to which it was adhered, left to stand for 30 minutes, and immersed in water at 37° C. for one day, after which the adhesive strength was measured.
エツチング 脱灰量 接着強度（ｓｅｃ）
（μｇ／ａｍ”） （ＭＰａ）１０ １
８．２±１，０ １２．０±３．１３０ ２２．１±
０．４ １１．７±１．７実施例６
０．５Ｍ ＤＴＰＡナトリウムム塩と０．５ＭＤＴＰ
Ａ鉄ナトリウム塩とを３＝２の比で混合し均一な水溶液
を得た（ｐＨ７，４とする）。得られた溶液４０μｍで
、生歯のエナメル質面を１０秒間、３０秒間エツチング
処理したのち、蒸溜水でよく洗浄し、気銃で表面に付着
した水分を除去し、被着面とした。添加モノマーとして
４−ＭＥＴＡを２％含むメチルメタクリレートにＴＢＢ
を添加し、下積法にてポリメチルメタクリレート粉末と
ともに被着面にとり、直系５．ＯＯｍ＋＋＋のアクリル
捧を被着面に垂直に立て、３０分間静置し３７℃の水中
に１日浸漬したのち接着強度を測定した。Etching Deashing amount Adhesive strength (sec)
(μg/am”) (MPa) 10 1
8.2±1,0 12.0±3.130 22.1±
0.4 11.7±1.7 Example 6 0.5M DTPA sodium salt and 0.5MDTP
A and iron sodium salt were mixed in a ratio of 3=2 to obtain a homogeneous aqueous solution (pH 7.4). The enamel surface of the natural tooth was etched for 10 seconds and 30 seconds using the obtained solution at 40 μm, then thoroughly washed with distilled water, and the water adhering to the surface was removed using an air gun to obtain an adhesion surface. TBB to methyl methacrylate containing 2% of 4-META as an added monomer.
was added to the adhering surface along with polymethyl methacrylate powder using the underlay method, and the direct line 5. An OOm+++ acrylic plate was stood vertically on the surface to which it was adhered, left to stand for 30 minutes, and immersed in water at 37° C. for one day, after which the adhesive strength was measured.
エツチング 脱灰量 接着強度（ｓｅｃ）
（μｇ／ａｍ”） （ＭＰａ）１０ ３
７．８±１．０ １０．０±２．０３０ ４２．２±
２．１ １１．５±１．９ＤＴＰＡ鉄アンモニウム塩と
を３：２の比で混合し均一な水溶液を得た（ｐＨ７，４
とする）。得られた溶液４０μｌで、エメリペーパー＃
６００で研削した生歯の象牙質部を１０秒間、３０秒間
エツチング処理したのち、蒸溜水でよく洗浄し。Etching Deashing amount Adhesive strength (sec)
(μg/am”) (MPa) 10 3
7.8±1.0 10.0±2.030 42.2±
2.1 11.5±1.9DTPA iron ammonium salt was mixed at a ratio of 3:2 to obtain a homogeneous aqueous solution (pH 7,4
). With 40 μl of the resulting solution, use Emery Paper #
After etching the dentin of the raw tooth ground with 600 millimeter for 10 seconds and 30 seconds, it was thoroughly washed with distilled water.
気銃で表面に付着した水分を除去し、被着面とした。添
加上ツマ−として４−ＭＥＴＡを２％含むメチルメタク
リレートにＴＢＢを添加し、下積法にてポリメチルメタ
クリレート粉末とともに被着面にとり、直系５．００ｍ
ｍのアクリル捧を被着面に垂直に立て、３０分間静置し
３７℃の水中に１０浸漬したのち接着強度を測定した。Moisture adhering to the surface was removed using an air gun to prepare the surface for adhesion. TBB was added to methyl methacrylate containing 2% 4-META as an additive, and it was placed on the surface to be adhered with polymethyl methacrylate powder using the underlay method, and the diameter was 5.00 m.
An acrylic slat of 1.5 m was stood perpendicular to the surface to which it was adhered, left to stand for 30 minutes, and immersed in water at 37° C. for 10 minutes, after which the adhesive strength was measured.
エツチング 脱灰量 接着強度（ｓｅｅ）
（μｇ／ｃｍ”） （ＭＰａ）１０
７．３±１．１ ８．９±１．２３０
９．５±Ｑ、２ ５．５±０．５特許出願人 帝国化
学産業株式会社Etching Demineralization amount Adhesive strength (see)
(μg/cm”) (MPa)10
7.3±1.1 8.9±1.230
9.5±Q, 2 5.5±0.5 Patent applicant Teikoku Kagaku Sangyo Co., Ltd.
Claims (1)
アミン五酢酸金属錯体のいづれか一つ又は両者を成分と
している歯牙エッチング用剤1. A tooth etching agent containing one or both of diethylenetriaminepentaacetic acid salt and diethylenetriaminepentaacetic acid metal complex.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP63058084A JP2648164B2 (en) | 1988-03-10 | 1988-03-10 | Etching agent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP63058084A JP2648164B2 (en) | 1988-03-10 | 1988-03-10 | Etching agent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH01230510A true JPH01230510A (en) | 1989-09-14 |
| JP2648164B2 JP2648164B2 (en) | 1997-08-27 |
Family
ID=13074058
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP63058084A Expired - Lifetime JP2648164B2 (en) | 1988-03-10 | 1988-03-10 | Etching agent |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2648164B2 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009131250A1 (en) | 2008-04-25 | 2009-10-29 | サンメディカル株式会社 | Easily removable curable composition for dental use |
-
1988
- 1988-03-10 JP JP63058084A patent/JP2648164B2/en not_active Expired - Lifetime
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009131250A1 (en) | 2008-04-25 | 2009-10-29 | サンメディカル株式会社 | Easily removable curable composition for dental use |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2648164B2 (en) | 1997-08-27 |
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