JPH01127961A - Liquid sample analyzer - Google Patents

Abstract

PURPOSE:To detect the defect of a cleaning operation to generate an alarm by detecting a liquid on a diluting cup side as well by means of a liquid detecting mechanism of a sampling nozzle. CONSTITUTION:A counter electrode 16 is provided to the sampling nozzle 4 of a sampling arm 20. The nozzle 4 and the counter electrode 16 conduct each other and send a signal to a control part 21 when both come into contact simultaneously with the liquid. The nozzle 4 touches the specimen of a test tube 1 when the nozzle 6 moves to the test tube 1 and the arm 20 descends. The arm 20 stops and the specimen is sucked by a cylinder 2 where the counter electrode 16 touches the specimen in succession thereto. The nozzle 4 descends down to the position lower than the top face of the diluting cup 5 on the cup 5 side to make sure that there is no conduction between the nozzle 4 and the electrode 16. The specimen is discharged and the next stage is started only when there is no conduction. However, decision is made that the suction of the cleaning liquid is defective if there is the conduction. The alarm is then generated and the measurement is stopped.

Description

DETAILED DESCRIPTION OF THE INVENTION [Field of Industrial Application] The present invention relates to a clinical testing device, and particularly to an automatic analyzer for analyzing liquids such as blood and urine.

[Conventional technology]

Conventional devices detect the presence or absence of a sample using an electrode (liquid level sensor), as described in Japanese Patent Application Laid-Open No. 58-102160,
It has been invented as a test information detection device that, when detected, combines it with other sample identification information. However, the detection function such as cleaning on the dilution cup side is not mentioned.

[Problem that the invention seeks to solve]

Conventionally, when separating a sample from a blood collection tube, a liquid detector is installed in the sampling nozzle to prevent the nozzle from being inserted into the sample more than necessary, or no consideration is given to the dilution cup.

Generally, the dilution cup is washed and used repeatedly, but without checking whether the washing liquid is being discharged and suctioned normally, upper and lower limits of the measurement data are set and an alarm is set if the measurement data falls outside of these limits. is out. However, in consideration of the number of visitors to the ion-selective electrode, a cleaning solution for an analyzer using an ion-selective electrode is generally a solution with an ion concentration similar to that of the sample. As a result, suction failure of the cleaning liquid occurs, and even if a sample is discharged and measured over the cleaning liquid, it will not fall out of the alarm setting level.

An object of the present invention is to provide a liquid sample analyzer that can detect a defective cleaning operation and generate an alarm without adding any special mechanism.

[Means for solving problems]

-a In order to minimize the insertion of the sampling nozzle into the sample and prevent contamination, the sampling nozzle is provided with a liquid detection mechanism. The purpose is achieved by using this detector to detect the liquid on the dilution cup side as well, and to issue an alarm.

[Effect]

The sampling arm is equipped with a liquid detector, and the sampling arm separates the sample, brings it to the dilution cup, and confirms the liquid detection signal when it descends below the top of the dilution cup. , no cleaning defects are overlooked, and no incorrect analysis data is output.

〔Example〕

An embodiment of the present invention will be described below with reference to FIG.

The sampling nozzle 4 moves to the test tube 1, sucks up the specimen 22 with the syringe 2, and as it is, the sampling nozzle 4 moves to the dilution cup 5 side and descends into the dilution cup 5.

The syringe 2 discharges the specimen 22 into the dilution cup 5, and at the same time the syringe 3 discharges the diluent 6 to dilute the specimen 22 by a constant amount. The sampling nozzle 1 moves up to sample the next specimen from the test tube. The diluted sample is sampler 7.
It is then sent to the zipper syringe 1 through the syringe nozzle 8.
3, it is guided to the ion selection electrode 9. Analyze the ion concentration in the diluted sample using an ion-selective electrode. The dilution cup 5 is then fed, and the remaining sample is sucked up by the suction pump 12 by changing the suction nozzle 1o. Subsequently, the cleaning liquid 15 is discharged from the nozzle 11 with the syringe 14, and as before, it is sucked up with the suction pump 12 and cleaned. The washed dilution cup is then sent and used for the next sample collection. Thereafter, the above-described operations are repeated to analyze the samples one after another.

Next, liquid level detection will be explained using FIG. 2.

The sampling nozzle 4 of the sampling arm 20 has a liquid level detection function, and the nozzle 4 is provided with a counter electrode 16. When the sampling nozzle 4 and the counter electrode 16 touch the liquid at the same time, the sampling nozzle 4 becomes conductive and sends a signal to the control section 21. Note that the counter electrode is mounted shifted 2 to 3 mm above the sampling nozzle 4.

Now, the sampling nozzle 4 moves to the test tube 1, and when the sampling arm 20 descends, the nozzle 4 moves to the sample in the test tube 1.
When the counter electrode 16 touches the sample, the sampling arm 20 stops descending, and the sample is sucked up by the syringe 2. On the dilution cup 5 side, the sampling nozzle 4 descends to a position below the top surface of the dilution cup 5, confirms that there is no conduction between the sampling nozzle 4 and the counter electrode 16, and discharges the sample only when there is no conduction. Enter the process. However, when there is continuity, it is determined that the suction of the cleaning liquid 15 is insufficient, an alarm is generated, and the measurement is stopped.

〔Effect of the invention〕

According to the present invention, it is possible to detect poor suction in cleaning without providing a special alarm mechanism for cleaning, and it is possible to provide a highly reliable analyzer for a measurement system.

[Brief explanation of the drawing]

FIG. 1 is a block diagram of an embodiment of the present invention, and FIG. 2 is a diagram showing a liquid detector consisting of a sampling nozzle and a counter electrode. 1... Test tube, 4... Sampling nozzle, 5...
- Dilution cup, 9... Ion selection electrode, 10... Suction nozzle, 11... Cleaning liquid discharge nozzle, 16...
Opposite.

Claims (1)

[Claims] 1. In a liquid sample analyzer consisting of a dilution cup that accommodates a specimen, a nozzle that aspirates and discharges a cleaning liquid to wash the dilution cup, a sampling nozzle that separates and distributes the specimen, and a liquid detector integrated with the sampling nozzle. A liquid sample analyzer characterized in that when discharging a sample into a dilution cup, the presence or absence of a cleaning liquid is detected, and if the liquid is detected, the sample is not discharged and a cleaning alarm is issued.