JP7839199B2 - 溶液相単一分子捕捉及び関連技術 - Google Patents

溶液相単一分子捕捉及び関連技術

Info

Publication number
JP7839199B2
JP7839199B2 JP2023572982A JP2023572982A JP7839199B2 JP 7839199 B2 JP7839199 B2 JP 7839199B2 JP 2023572982 A JP2023572982 A JP 2023572982A JP 2023572982 A JP2023572982 A JP 2023572982A JP 7839199 B2 JP7839199 B2 JP 7839199B2
Authority
JP
Japan
Prior art keywords
analyte
binding
molecule
supramolecular
molecules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2023572982A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024521801A (ja
JP2024521801A5 (https=
Inventor
アシュウィン ゴピナート
ポール ロゼムンド
リシャブ シェティ
シェーン ボーウェン
レイチェル ガリミディ
ダジュン ユアン
Original Assignee
ノーティラス・サブシディアリー・インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ノーティラス・サブシディアリー・インコーポレイテッド filed Critical ノーティラス・サブシディアリー・インコーポレイテッド
Publication of JP2024521801A publication Critical patent/JP2024521801A/ja
Publication of JP2024521801A5 publication Critical patent/JP2024521801A5/ja
Application granted granted Critical
Publication of JP7839199B2 publication Critical patent/JP7839199B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346—Nanoparticles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2023572982A 2021-05-27 2022-05-26 溶液相単一分子捕捉及び関連技術 Active JP7839199B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163194005P 2021-05-27 2021-05-27
US63/194,005 2021-05-27
US202163249367P 2021-09-28 2021-09-28
US63/249,367 2021-09-28
PCT/US2022/031155 WO2022251514A1 (en) 2021-05-27 2022-05-26 Solution phase single molecule capture and associated techniques

Publications (3)

Publication Number Publication Date
JP2024521801A JP2024521801A (ja) 2024-06-04
JP2024521801A5 JP2024521801A5 (https=) 2025-05-14
JP7839199B2 true JP7839199B2 (ja) 2026-04-01

Family

ID=82156558

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023572982A Active JP7839199B2 (ja) 2021-05-27 2022-05-26 溶液相単一分子捕捉及び関連技術

Country Status (4)

Country Link
US (1) US20220381777A1 (https=)
EP (1) EP4348252A1 (https=)
JP (1) JP7839199B2 (https=)
WO (1) WO2022251514A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102491083B1 (ko) * 2019-07-26 2023-01-26 엘지전자 주식회사 무선통신 시스템에서 단말의 물리 하향링크 제어채널 모니터링 방법 및 상기 방법을 이용하는 장치

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130059741A1 (en) 2010-05-13 2013-03-07 Illumina, Inc. Binding assays for markers
WO2017204294A1 (ja) 2016-05-25 2017-11-30 株式会社ニコン 標的生体分子の特定方法、標的生体分子特定用ビーズ、ビーズのセット、及び標的生体分子特定装置

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101338136B1 (ko) * 2012-05-03 2013-12-06 한국과학기술연구원 금 나노입자를 이용하여 신호 증폭도가 향상된, 표적 물질의 다중화 처리 분석법과 그 시스템
US9512422B2 (en) * 2013-02-26 2016-12-06 Illumina, Inc. Gel patterned surfaces
US20170234866A1 (en) * 2016-02-11 2017-08-17 Massachusetts Institute Of Technology Multiplexed lateral flow assay
US10731166B2 (en) * 2016-03-18 2020-08-04 Caris Science, Inc. Oligonucleotide probes and uses thereof
CN110462057B (zh) * 2017-03-12 2024-06-18 伊利蒂卡有限公司 数字分子测定
US20210095333A1 (en) * 2019-09-30 2021-04-01 X Development Llc Quantification of molecules using nucleic acid strand displacement detection
US11976382B2 (en) * 2019-10-23 2024-05-07 Boise State University Nucleic acid based biosensor and methods thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130059741A1 (en) 2010-05-13 2013-03-07 Illumina, Inc. Binding assays for markers
WO2017204294A1 (ja) 2016-05-25 2017-11-30 株式会社ニコン 標的生体分子の特定方法、標的生体分子特定用ビーズ、ビーズのセット、及び標的生体分子特定装置

Also Published As

Publication number Publication date
US20220381777A1 (en) 2022-12-01
WO2022251514A1 (en) 2022-12-01
EP4348252A1 (en) 2024-04-10
JP2024521801A (ja) 2024-06-04

Similar Documents

Publication Publication Date Title
EP2054711A1 (en) A microarray system and a process for producing microarrays
US20240118274A1 (en) Structure and methods for detection of sample analytes
WO2019178033A1 (en) Ultrahigh throughput protein discovery
US20240027433A1 (en) Structure and methods for detection of sample analytes
JP7839199B2 (ja) 溶液相単一分子捕捉及び関連技術
JP2024521801A5 (https=)
JP2024507375A (ja) サンプル検体の検出のための構造体及び方法
JP5133895B2 (ja) 生体分子の親和性を測定する方法
JP7759399B2 (ja) マイクロ流体デバイス上へのタンパク質共局在デバイス（ｐｃｄ）の組み込み
CN117529661A (zh) 溶液相单分子捕获和相关技术
US20220268768A1 (en) Structure and methods for detection of sample analytes
WO2025010185A1 (en) Methods and systems for characterizing entities on a substrate
US20220170918A1 (en) Substrate for single molecule organization
HK40100649A (zh) 用於检测样品分析物的结构和方法

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20231124

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20250128

A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A711

Effective date: 20250314

A524 Written submission of copy of amendment under article 19 pct

Free format text: JAPANESE INTERMEDIATE CODE: A524

Effective date: 20250422

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20250805

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20251104

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20260303

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20260319

R150 Certificate of patent or registration of utility model

Ref document number: 7839199

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150