JP7835735B2 - シクロデキストリンによるコレステロール結晶塞栓症の治療方法 - Google Patents
シクロデキストリンによるコレステロール結晶塞栓症の治療方法Info
- Publication number
- JP7835735B2 JP7835735B2 JP2023513682A JP2023513682A JP7835735B2 JP 7835735 B2 JP7835735 B2 JP 7835735B2 JP 2023513682 A JP2023513682 A JP 2023513682A JP 2023513682 A JP2023513682 A JP 2023513682A JP 7835735 B2 JP7835735 B2 JP 7835735B2
- Authority
- JP
- Japan
- Prior art keywords
- individual
- cyclodextrin
- hydroxypropyl
- cholesterol crystals
- crystals
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/724—Cyclodextrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063071222P | 2020-08-27 | 2020-08-27 | |
| US63/071,222 | 2020-08-27 | ||
| PCT/US2021/048072 WO2022047241A1 (en) | 2020-08-27 | 2021-08-27 | Methods for the treatment of cholesterol crystal embolization with cyclodextrins |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023543133A JP2023543133A (ja) | 2023-10-13 |
| JP2023543133A5 JP2023543133A5 (https=) | 2024-08-27 |
| JP7835735B2 true JP7835735B2 (ja) | 2026-03-25 |
Family
ID=80353289
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023513682A Active JP7835735B2 (ja) | 2020-08-27 | 2021-08-27 | シクロデキストリンによるコレステロール結晶塞栓症の治療方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20230330133A1 (https=) |
| EP (1) | EP4203972A4 (https=) |
| JP (1) | JP7835735B2 (https=) |
| KR (1) | KR20230096975A (https=) |
| CN (1) | CN116322643A (https=) |
| AU (1) | AU2021333902A1 (https=) |
| BR (1) | BR112023003455A2 (https=) |
| CA (1) | CA3190563A1 (https=) |
| IL (1) | IL300806A (https=) |
| MX (1) | MX2023002419A (https=) |
| WO (1) | WO2022047241A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018517046A (ja) | 2015-06-10 | 2018-06-28 | ビテス， インコーポレイテッド | ヒドロキシプロピル−ベータ−シクロデキストリン組成物および方法 |
| JP2024509376A (ja) * | 2021-02-18 | 2024-03-01 | ベレン セラピューティクス ピー．ビー．シー． | 家族性ヘテロ接合型及びホモ接合型高コレステロール血症のシクロデキストリンによる治療方法 |
| WO2023156966A1 (en) | 2022-02-18 | 2023-08-24 | Beren Therapeutics P.B.C. | Compositions of hydroxypropyl-beta-cyclodextrin and methods of purifying the same |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4877778A (en) * | 1987-07-01 | 1989-10-31 | The Children's Medical Center Corporation | Method of enhancing lipophile transport using cyclodextrin derivatives |
| MX371073B (es) * | 2012-04-13 | 2020-01-15 | L&F Res Llc | Método para utilizar ciclodextrina. |
-
2021
- 2021-08-27 KR KR1020237010389A patent/KR20230096975A/ko not_active Withdrawn
- 2021-08-27 IL IL300806A patent/IL300806A/en unknown
- 2021-08-27 MX MX2023002419A patent/MX2023002419A/es unknown
- 2021-08-27 AU AU2021333902A patent/AU2021333902A1/en not_active Abandoned
- 2021-08-27 CN CN202180053198.8A patent/CN116322643A/zh active Pending
- 2021-08-27 BR BR112023003455A patent/BR112023003455A2/pt not_active Application Discontinuation
- 2021-08-27 EP EP21862876.6A patent/EP4203972A4/en active Pending
- 2021-08-27 US US18/043,013 patent/US20230330133A1/en active Pending
- 2021-08-27 WO PCT/US2021/048072 patent/WO2022047241A1/en not_active Ceased
- 2021-08-27 CA CA3190563A patent/CA3190563A1/en active Pending
- 2021-08-27 JP JP2023513682A patent/JP7835735B2/ja active Active
Non-Patent Citations (2)
| Title |
|---|
| GREBE, A.，Targeting cholesterol crystals in atherosclerosis with cholesterol solubilizing 2-hydroxypropyl-β-cyclodextrin，2016年，pp.1-132，URL:https://d-nb.info/1124540296/34 |
| The Journal of Biomedical Research，2017年，31(2)，pp.82-94 |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2021333902A1 (en) | 2023-03-16 |
| CN116322643A (zh) | 2023-06-23 |
| US20230330133A1 (en) | 2023-10-19 |
| BR112023003455A2 (pt) | 2023-05-02 |
| EP4203972A1 (en) | 2023-07-05 |
| MX2023002419A (es) | 2023-07-11 |
| KR20230096975A (ko) | 2023-06-30 |
| IL300806A (en) | 2023-04-01 |
| CA3190563A1 (en) | 2022-03-03 |
| WO2022047241A1 (en) | 2022-03-03 |
| JP2023543133A (ja) | 2023-10-13 |
| EP4203972A4 (en) | 2024-07-17 |
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