IL300806A - Methods for the treatment of embolization of cholesterol crystals with cyclodextrins - Google Patents

Methods for the treatment of embolization of cholesterol crystals with cyclodextrins

Info

Publication number
IL300806A
IL300806A IL300806A IL30080623A IL300806A IL 300806 A IL300806 A IL 300806A IL 300806 A IL300806 A IL 300806A IL 30080623 A IL30080623 A IL 30080623A IL 300806 A IL300806 A IL 300806A
Authority
IL
Israel
Prior art keywords
individual
cyclodextrin
amount
beta
cholesterol crystals
Prior art date
Application number
IL300806A
Other languages
English (en)
Hebrew (he)
Original Assignee
Beren Therapeutics P B C
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beren Therapeutics P B C filed Critical Beren Therapeutics P B C
Publication of IL300806A publication Critical patent/IL300806A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/724Cyclodextrins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
IL300806A 2020-08-27 2021-08-27 Methods for the treatment of embolization of cholesterol crystals with cyclodextrins IL300806A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063071222P 2020-08-27 2020-08-27
PCT/US2021/048072 WO2022047241A1 (en) 2020-08-27 2021-08-27 Methods for the treatment of cholesterol crystal embolization with cyclodextrins

Publications (1)

Publication Number Publication Date
IL300806A true IL300806A (en) 2023-04-01

Family

ID=80353289

Family Applications (1)

Application Number Title Priority Date Filing Date
IL300806A IL300806A (en) 2020-08-27 2021-08-27 Methods for the treatment of embolization of cholesterol crystals with cyclodextrins

Country Status (11)

Country Link
US (1) US20230330133A1 (https=)
EP (1) EP4203972A4 (https=)
JP (1) JP7835735B2 (https=)
KR (1) KR20230096975A (https=)
CN (1) CN116322643A (https=)
AU (1) AU2021333902A1 (https=)
BR (1) BR112023003455A2 (https=)
CA (1) CA3190563A1 (https=)
IL (1) IL300806A (https=)
MX (1) MX2023002419A (https=)
WO (1) WO2022047241A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2988529A1 (en) 2015-06-10 2016-12-15 Vtesse, Inc. Hydroxypropyl beta-cyclodextrin compositions and methods
AU2022222756A1 (en) * 2021-02-18 2023-09-14 Beren Therapeutics P.B.C. Methods for the treatment of familial heterozygous and homozygous hypercholesterolemia with cyclodextrins
WO2023156966A1 (en) 2022-02-18 2023-08-24 Beren Therapeutics P.B.C. Compositions of hydroxypropyl-beta-cyclodextrin and methods of purifying the same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4877778A (en) * 1987-07-01 1989-10-31 The Children's Medical Center Corporation Method of enhancing lipophile transport using cyclodextrin derivatives
CN104244956B (zh) * 2012-04-13 2020-04-17 L&F研究有限公司 使用环糊精的方法

Also Published As

Publication number Publication date
CA3190563A1 (en) 2022-03-03
EP4203972A1 (en) 2023-07-05
US20230330133A1 (en) 2023-10-19
JP7835735B2 (ja) 2026-03-25
KR20230096975A (ko) 2023-06-30
BR112023003455A2 (pt) 2023-05-02
MX2023002419A (es) 2023-07-11
EP4203972A4 (en) 2024-07-17
WO2022047241A1 (en) 2022-03-03
AU2021333902A1 (en) 2023-03-16
CN116322643A (zh) 2023-06-23
JP2023543133A (ja) 2023-10-13

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