JP7774074B2 - 腫瘍アブレーション器具及び技術 - Google Patents

腫瘍アブレーション器具及び技術

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Publication number
JP7774074B2
JP7774074B2 JP2023561062A JP2023561062A JP7774074B2 JP 7774074 B2 JP7774074 B2 JP 7774074B2 JP 2023561062 A JP2023561062 A JP 2023561062A JP 2023561062 A JP2023561062 A JP 2023561062A JP 7774074 B2 JP7774074 B2 JP 7774074B2
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Prior art keywords
electrode
tumor
bioimpedance
electroporation
applications
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English (en)
Japanese (ja)
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JP2024520990A5 (https=
JP2024520990A (ja
Inventor
タフ,ユバル
オムリ,ベン
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スナイプ メディカル リミテッド
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Publication of JP2024520990A5 publication Critical patent/JP2024520990A5/ja
Priority to JP2025189311A priority Critical patent/JP2026027412A/ja
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/1206Generators therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B18/1477Needle-like probes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B18/1492Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B2017/00982General structural features
    • A61B2017/00991Telescopic means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053Mechanical features of the instrument of device
    • A61B2018/00059Material properties
    • A61B2018/00071Electrical conductivity
    • A61B2018/00083Electrical conductivity low, i.e. electrically insulating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053Mechanical features of the instrument of device
    • A61B2018/0016Energy applicators arranged in a two- or three dimensional array
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053Mechanical features of the instrument of device
    • A61B2018/00166Multiple lumina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053Mechanical features of the instrument of device
    • A61B2018/00184Moving parts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053Mechanical features of the instrument of device
    • A61B2018/00184Moving parts
    • A61B2018/00196Moving parts reciprocating lengthwise
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00541Lung or bronchi
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00577Ablation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00613Irreversible electroporation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00642Sensing and controlling the application of energy with feedback, i.e. closed loop control
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00696Controlled or regulated parameters
    • A61B2018/0072Current
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00696Controlled or regulated parameters
    • A61B2018/00732Frequency
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00696Controlled or regulated parameters
    • A61B2018/00767Voltage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00773Sensed parameters
    • A61B2018/00839Bioelectrical parameters, e.g. ECG, EEG
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00773Sensed parameters
    • A61B2018/00875Resistance or impedance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B2018/1405Electrodes having a specific shape
    • A61B2018/1425Needle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B2018/1405Electrodes having a specific shape
    • A61B2018/1425Needle
    • A61B2018/143Needle multiple needles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/06Electrodes for high-frequency therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/327Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation

Landscapes

  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Otolaryngology (AREA)
  • Physics & Mathematics (AREA)
  • Plasma & Fusion (AREA)
  • Cardiology (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Surgical Instruments (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Electrotherapy Devices (AREA)
JP2023561062A 2021-05-22 2022-05-10 腫瘍アブレーション器具及び技術 Active JP7774074B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025189311A JP2026027412A (ja) 2021-05-22 2025-11-10 腫瘍アブレーション器具及び技術

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163191992P 2021-05-22 2021-05-22
US63/191,992 2021-05-22
PCT/IB2022/054313 WO2022248957A1 (en) 2021-05-22 2022-05-10 Tumor ablation tools and techniques

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025189311A Division JP2026027412A (ja) 2021-05-22 2025-11-10 腫瘍アブレーション器具及び技術

Publications (3)

Publication Number Publication Date
JP2024520990A JP2024520990A (ja) 2024-05-28
JP2024520990A5 JP2024520990A5 (https=) 2025-05-07
JP7774074B2 true JP7774074B2 (ja) 2025-11-20

Family

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JP2023561062A Active JP7774074B2 (ja) 2021-05-22 2022-05-10 腫瘍アブレーション器具及び技術
JP2025189311A Pending JP2026027412A (ja) 2021-05-22 2025-11-10 腫瘍アブレーション器具及び技術

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Country Status (7)

Country Link
US (1) US20240206937A1 (https=)
EP (1) EP4340759A4 (https=)
JP (2) JP7774074B2 (https=)
CN (1) CN117241751A (https=)
AU (1) AU2022282840A1 (https=)
CA (1) CA3216185A1 (https=)
WO (1) WO2022248957A1 (https=)

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JP2001037775A (ja) 1999-07-26 2001-02-13 Olympus Optical Co Ltd 治療装置
JP2002507924A (ja) 1997-07-03 2002-03-12 ネオサーミア コーポレイション 生体組織の所定体積の治療的焼灼のための方法および装置
US20040024399A1 (en) 1995-04-13 2004-02-05 Arthrocare Corporation Method for repairing damaged intervertebral discs
JP2005503864A (ja) 2001-09-28 2005-02-10 リタ メディカル システムズ インコーポレイテッド インピーダンス制御組織剥離装置および方法
JP2010012145A (ja) 2008-07-07 2010-01-21 Nippon Zeon Co Ltd 電極カテーテル
JP2013244408A (ja) 2012-05-23 2013-12-09 Biosense Webster (Israel) Ltd 気管支カテーテル
US20160158561A1 (en) 2007-05-17 2016-06-09 Cardiac Pacemakers, Inc. Systems and methods for fixating transvenously implanted medical devices
JP2017527395A (ja) 2014-09-15 2017-09-21 エシコン・インコーポレイテッドEthicon, Incorporated 治療薬を組織に標的化送達するためのシステム
JP2018535066A (ja) 2015-09-30 2018-11-29 ジ・エ・エッメ・エッセ・エッレ・エッレ 組織を電磁アブレーションするデバイス
JP2019513032A (ja) 2016-03-09 2019-05-23 カーディオノミック,インク. 心収縮神経刺激システムおよび方法
JP2019111311A (ja) 2017-12-22 2019-07-11 財團法人工業技術研究院Industrial Technology Research Institute バイポーラ電極プローブ
US20200008883A1 (en) 2017-03-08 2020-01-09 Children's National Medical Center Fluoroless vascular sheath manipulation and electrogram monitoring
US20200155227A1 (en) 2018-10-23 2020-05-21 Boston Scientific Scimed, Inc. Ablation probe system with center working channel
US20200269059A1 (en) 2019-02-20 2020-08-27 Ablation Innovations, LLC Apparatus, systems, and methods to improve atrial fibrillation outcomes involving the left atrial appendage
WO2021044312A1 (en) 2019-09-04 2021-03-11 Arga' Medtech Sa Ablation assembly to treat target regions of tissue in organs
JP2021526051A (ja) 2018-05-30 2021-09-30 クレオ・メディカル・リミテッドCreo Medical Limited 電気手術器具
WO2022090436A1 (en) 2020-10-29 2022-05-05 Koninklijke Philips N.V. Catheter, catheter system and processing system for determining parameters during a tissue puncturing process
JP2022529058A (ja) 2019-04-18 2022-06-16 ギャラリー,インコーポレイテッド 異常組織を治療するための器械、及びシステム、

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US5683384A (en) * 1993-11-08 1997-11-04 Zomed Multiple antenna ablation apparatus
US6706039B2 (en) 1998-07-07 2004-03-16 Medtronic, Inc. Method and apparatus for creating a bi-polar virtual electrode used for the ablation of tissue
US8414580B2 (en) * 2004-04-20 2013-04-09 Boston Scientific Scimed, Inc. Co-access bipolar ablation probe
US8361066B2 (en) * 2009-01-12 2013-01-29 Ethicon Endo-Surgery, Inc. Electrical ablation devices
US20120310230A1 (en) 2011-06-01 2012-12-06 Angiodynamics, Inc. Coaxial dual function probe and method of use
WO2014031800A1 (en) * 2012-08-22 2014-02-27 Energize Medical Llc Therapeutic energy systems
US20210137410A1 (en) * 2014-12-15 2021-05-13 Virginia Tech Intellectual Properties, Inc. Intelligent surgical probe for real-time monitoring of electroporation-based therapies

Patent Citations (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040024399A1 (en) 1995-04-13 2004-02-05 Arthrocare Corporation Method for repairing damaged intervertebral discs
JP2002507924A (ja) 1997-07-03 2002-03-12 ネオサーミア コーポレイション 生体組織の所定体積の治療的焼灼のための方法および装置
JP2001037775A (ja) 1999-07-26 2001-02-13 Olympus Optical Co Ltd 治療装置
JP2005503864A (ja) 2001-09-28 2005-02-10 リタ メディカル システムズ インコーポレイテッド インピーダンス制御組織剥離装置および方法
US20160158561A1 (en) 2007-05-17 2016-06-09 Cardiac Pacemakers, Inc. Systems and methods for fixating transvenously implanted medical devices
JP2010012145A (ja) 2008-07-07 2010-01-21 Nippon Zeon Co Ltd 電極カテーテル
JP2013244408A (ja) 2012-05-23 2013-12-09 Biosense Webster (Israel) Ltd 気管支カテーテル
JP2017527395A (ja) 2014-09-15 2017-09-21 エシコン・インコーポレイテッドEthicon, Incorporated 治療薬を組織に標的化送達するためのシステム
JP2018535066A (ja) 2015-09-30 2018-11-29 ジ・エ・エッメ・エッセ・エッレ・エッレ 組織を電磁アブレーションするデバイス
JP2019513032A (ja) 2016-03-09 2019-05-23 カーディオノミック,インク. 心収縮神経刺激システムおよび方法
US20200008883A1 (en) 2017-03-08 2020-01-09 Children's National Medical Center Fluoroless vascular sheath manipulation and electrogram monitoring
JP2019111311A (ja) 2017-12-22 2019-07-11 財團法人工業技術研究院Industrial Technology Research Institute バイポーラ電極プローブ
JP2021526051A (ja) 2018-05-30 2021-09-30 クレオ・メディカル・リミテッドCreo Medical Limited 電気手術器具
US20200155227A1 (en) 2018-10-23 2020-05-21 Boston Scientific Scimed, Inc. Ablation probe system with center working channel
US20200269059A1 (en) 2019-02-20 2020-08-27 Ablation Innovations, LLC Apparatus, systems, and methods to improve atrial fibrillation outcomes involving the left atrial appendage
JP2022529058A (ja) 2019-04-18 2022-06-16 ギャラリー,インコーポレイテッド 異常組織を治療するための器械、及びシステム、
WO2021044312A1 (en) 2019-09-04 2021-03-11 Arga' Medtech Sa Ablation assembly to treat target regions of tissue in organs
JP2022546736A (ja) 2019-09-04 2022-11-07 アルガ′ メドテック エスア 臓器内の組織の標的領域を治療するためのアブレーションアセンブリ
WO2022090436A1 (en) 2020-10-29 2022-05-05 Koninklijke Philips N.V. Catheter, catheter system and processing system for determining parameters during a tissue puncturing process

Also Published As

Publication number Publication date
EP4340759A1 (en) 2024-03-27
CA3216185A1 (en) 2022-12-01
AU2022282840A1 (en) 2023-11-02
CN117241751A (zh) 2023-12-15
JP2026027412A (ja) 2026-02-18
US20240206937A1 (en) 2024-06-27
WO2022248957A1 (en) 2022-12-01
JP2024520990A (ja) 2024-05-28
EP4340759A4 (en) 2025-04-16

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