JP7737978B2 - Ｗｔ－１に特異的なｔ細胞免疫療法 - Google Patents

Ｗｔ－１に特異的なｔ細胞免疫療法

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Publication number
JP7737978B2
JP7737978B2 JP2022510984A JP2022510984A JP7737978B2 JP 7737978 B2 JP7737978 B2 JP 7737978B2 JP 2022510984 A JP2022510984 A JP 2022510984A JP 2022510984 A JP2022510984 A JP 2022510984A JP 7737978 B2 JP7737978 B2 JP 7737978B2
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cells
cell
seq
amino acid
acid sequence
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JP2022547809A (ja
JP2022547809A5 (enExample
Inventor
シュミット，トーマス・エム
シャピュイ，オード・ジー
グリーンバーグ，フィリップ・ディー
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Fred Hutchinson Cancer Center
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Fred Hutchinson Cancer Center
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/15—Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
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    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
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    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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JP2022510984A 2019-08-20 2020-08-19 Ｗｔ－１に特異的なｔ細胞免疫療法 Active JP7737978B2 (ja)

Applications Claiming Priority (3)

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US201962889519P 2019-08-20 2019-08-20
US62/889,519 2019-08-20
PCT/US2020/047071 WO2021034976A1 (en) 2019-08-20 2020-08-19 T-cell immunotherapy specific for wt-1

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JP2022547809A JP2022547809A (ja) 2022-11-16
JP2022547809A5 JP2022547809A5 (enExample) 2023-08-29
JP7737978B2 true JP7737978B2 (ja) 2025-09-11

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US (1) US12653886B2 (enExample)
EP (1) EP4017872A1 (enExample)
JP (1) JP7737978B2 (enExample)
KR (1) KR20220050176A (enExample)
CN (1) CN114555790B (enExample)
AU (1) AU2020334064A1 (enExample)
CA (1) CA3147717A1 (enExample)
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GB202406990D0 (en) * 2024-05-16 2024-07-03 Univ Oxford Innovation Ltd T cell receptors and uses thereof
WO2025245169A1 (en) 2024-05-21 2025-11-27 Fred Hutchinson Cancer Center Immunotherapy cells equipped with a collagen-targeting payload
WO2026125718A1 (en) * 2024-12-13 2026-06-18 Immunoscape Pte. Ltd. Human t cell receptors and uses thereof

Citations (2)

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Publication number Priority date Publication date Assignee Title
WO2016022400A1 (en) 2014-08-04 2016-02-11 Fred Hutchinson Cancer Research Center T cell immunotherapy specific for wt-1
JP2017501130A (ja) 2013-11-22 2017-01-12 ザ ボード オブ トラスティーズ オブ ザ ユニバーシティ オブ イリノイ 改変された高親和性ヒトｔ細胞受容体

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