JP7675016B2 - ムチン-16に対するヒト化抗体およびそれを使用する方法 - Google Patents
ムチン-16に対するヒト化抗体およびそれを使用する方法 Download PDFInfo
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- JP7675016B2 JP7675016B2 JP2021565883A JP2021565883A JP7675016B2 JP 7675016 B2 JP7675016 B2 JP 7675016B2 JP 2021565883 A JP2021565883 A JP 2021565883A JP 2021565883 A JP2021565883 A JP 2021565883A JP 7675016 B2 JP7675016 B2 JP 7675016B2
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- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
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- C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3076—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties
- C07K16/3092—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties against tumour-associated mucins
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| MX2018004721A (es) | 2015-10-23 | 2018-07-06 | Eureka Therapeutics Inc | Construcciones quimericas anticuerpo/receptor de celulas t y usos de las mismas. |
| JP7538601B2 (ja) | 2017-04-26 | 2024-08-22 | ユーリカ セラピューティックス, インコーポレイテッド | キメラ活性化受容体及びキメラ刺激受容体を発現する細胞並びにその使用 |
| CN113366022B (zh) | 2018-11-16 | 2025-11-21 | 纪念斯隆凯特琳癌症中心 | 针对粘蛋白-16的抗体及其使用方法 |
| WO2020232247A1 (en) | 2019-05-14 | 2020-11-19 | Provention Bio, Inc. | Methods and compositions for preventing type 1 diabetes |
| IL298999A (en) | 2020-06-11 | 2023-02-01 | Provention Bio Inc | Methods and compositions for the prevention of type 1 diabetes |
| WO2022197907A2 (en) * | 2021-03-18 | 2022-09-22 | Memorial Sloan-Kettering Cancer Center | Methods for treating gynecologic cancer using combination therapy with anti-muc16 x cd3 multispecific antibodies and vegf inhibitors |
| WO2022204249A1 (en) * | 2021-03-24 | 2022-09-29 | Memorial Sloan-Kettering Cancer Center | Variants of humanized anti-muc16 ectodomain antibodies for treatment of muc16 overexpressing tumors |
| JP2024520444A (ja) | 2021-05-24 | 2024-05-24 | プロヴェンション・バイオ・インコーポレイテッド | 1型糖尿病を治療するための方法 |
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| JP2013529061A (ja) | 2010-03-26 | 2013-07-18 | メモリアル スローン−ケタリング キャンサー センター | Muc16に対する抗体およびその使用方法 |
| JP2016508728A (ja) | 2013-02-26 | 2016-03-24 | メモリアル スローン−ケタリング キャンサー センター | 免疫療法のための組成物および方法 |
| JP2018509907A (ja) | 2015-03-17 | 2018-04-12 | メモリアル スローン ケタリング キャンサー センター | 抗muc16抗体及びその使用 |
| US20180258048A1 (en) | 2017-03-15 | 2018-09-13 | Silverback Therapeutics, Inc. | Benzazepine compounds, conjugates, and uses thereof |
| WO2018231759A1 (en) | 2017-06-12 | 2018-12-20 | Obsidian Therapeutics, Inc. | Pde5 compositions and methods for immunotherapy |
| WO2019079357A1 (en) | 2017-10-17 | 2019-04-25 | Silverback Therapeutics, Inc. | Tnik modulators, conjugates, and uses thereof |
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| KR20230148844A (ko) * | 2016-03-29 | 2023-10-25 | 유니버시티 오브 써던 캘리포니아 | 암을 표적하는 키메라 항원 수용체 |
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| JP2013529061A (ja) | 2010-03-26 | 2013-07-18 | メモリアル スローン−ケタリング キャンサー センター | Muc16に対する抗体およびその使用方法 |
| JP2016508728A (ja) | 2013-02-26 | 2016-03-24 | メモリアル スローン−ケタリング キャンサー センター | 免疫療法のための組成物および方法 |
| JP2018509907A (ja) | 2015-03-17 | 2018-04-12 | メモリアル スローン ケタリング キャンサー センター | 抗muc16抗体及びその使用 |
| US20180258048A1 (en) | 2017-03-15 | 2018-09-13 | Silverback Therapeutics, Inc. | Benzazepine compounds, conjugates, and uses thereof |
| WO2018231759A1 (en) | 2017-06-12 | 2018-12-20 | Obsidian Therapeutics, Inc. | Pde5 compositions and methods for immunotherapy |
| WO2019079357A1 (en) | 2017-10-17 | 2019-04-25 | Silverback Therapeutics, Inc. | Tnik modulators, conjugates, and uses thereof |
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| CN114127116A (zh) | 2022-03-01 |
| WO2020227538A1 (en) | 2020-11-12 |
| EP3966248A4 (en) | 2023-04-12 |
| JP2022531454A (ja) | 2022-07-06 |
| KR20220007873A (ko) | 2022-01-19 |
| US20220235143A1 (en) | 2022-07-28 |
| EP3966248A1 (en) | 2022-03-16 |
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