JP7670272B2 - 環状オリゴ糖の製造方法、環状オリゴ糖および包接剤 - Google Patents

環状オリゴ糖の製造方法、環状オリゴ糖および包接剤 Download PDF

Info

Publication number
JP7670272B2
JP7670272B2 JP2021154167A JP2021154167A JP7670272B2 JP 7670272 B2 JP7670272 B2 JP 7670272B2 JP 2021154167 A JP2021154167 A JP 2021154167A JP 2021154167 A JP2021154167 A JP 2021154167A JP 7670272 B2 JP7670272 B2 JP 7670272B2
Authority
JP
Japan
Prior art keywords
group
formula
tert
acetyl
fluorenylmethylcarboxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2021154167A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023045634A5 (https=
JP2023045634A (ja
Inventor
敏材 野上
智昭 濱多
和弘 真島
貴宏 川野
泰彦 村本
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Koganei Corp
Tottori University NUC
Original Assignee
Koganei Corp
Tottori University NUC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koganei Corp, Tottori University NUC filed Critical Koganei Corp
Priority to JP2021154167A priority Critical patent/JP7670272B2/ja
Priority to US18/693,800 priority patent/US20240400723A1/en
Priority to PCT/JP2022/028680 priority patent/WO2023047790A1/ja
Priority to EP22872546.1A priority patent/EP4406977A4/en
Publication of JP2023045634A publication Critical patent/JP2023045634A/ja
Publication of JP2023045634A5 publication Critical patent/JP2023045634A5/ja
Application granted granted Critical
Publication of JP7670272B2 publication Critical patent/JP7670272B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
    • C08B37/0015—Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
    • C07H5/06—Aminosugars
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00—Electrolytic production of organic compounds
    • C25B3/01—Products
    • C25B3/05—Heterocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00—Electrolytic production of organic compounds
    • C25B3/01—Products
    • C25B3/07—Oxygen containing compounds
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00—Electrolytic production of organic compounds
    • C25B3/01—Products
    • C25B3/09—Nitrogen containing compounds
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00—Electrolytic production of organic compounds
    • C25B3/20—Processes
    • C25B3/29—Coupling reactions
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Metallurgy (AREA)
  • Electrochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
JP2021154167A 2021-09-22 2021-09-22 環状オリゴ糖の製造方法、環状オリゴ糖および包接剤 Active JP7670272B2 (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2021154167A JP7670272B2 (ja) 2021-09-22 2021-09-22 環状オリゴ糖の製造方法、環状オリゴ糖および包接剤
US18/693,800 US20240400723A1 (en) 2021-09-22 2022-07-26 Method for producing cyclic oligosaccharide, cyclic oligosaccharide and inclusion agent
PCT/JP2022/028680 WO2023047790A1 (ja) 2021-09-22 2022-07-26 環状オリゴ糖の製造方法、環状オリゴ糖および包接剤
EP22872546.1A EP4406977A4 (en) 2021-09-22 2022-07-26 PROCESS FOR PRODUCING CYCLIC OLIGOSACCHARIDE, CYCLIC OLIGOSACCHARIDE AND COMPLEXING AGENT

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2021154167A JP7670272B2 (ja) 2021-09-22 2021-09-22 環状オリゴ糖の製造方法、環状オリゴ糖および包接剤

Publications (3)

Publication Number Publication Date
JP2023045634A JP2023045634A (ja) 2023-04-03
JP2023045634A5 JP2023045634A5 (https=) 2024-04-22
JP7670272B2 true JP7670272B2 (ja) 2025-04-30

Family

ID=85720484

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021154167A Active JP7670272B2 (ja) 2021-09-22 2021-09-22 環状オリゴ糖の製造方法、環状オリゴ糖および包接剤

Country Status (4)

Country Link
US (1) US20240400723A1 (https=)
EP (1) EP4406977A4 (https=)
JP (1) JP7670272B2 (https=)
WO (1) WO2023047790A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118894895A (zh) * 2024-07-18 2024-11-05 吉林大学 一种新型疫苗佐剂mpla中间体的合成方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998022795A1 (en) 1996-11-22 1998-05-28 The Regents Of The University Of California Chemical microsensors for detection of explosives and chemical warfare agents
JP2017165725A (ja) 2016-03-09 2017-09-21 国立大学法人鳥取大学 糖の製造方法
US20180362814A1 (en) 2017-06-14 2018-12-20 City University Of Hong Kong Adhesive system, method of manufacture thereof and biological kit comprising same
JP2020138931A (ja) 2019-02-28 2020-09-03 国立大学法人鳥取大学 糖鎖の製造方法、糖鎖合成用のビルディングブロックおよび化合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0768282B2 (ja) * 1988-09-07 1995-07-26 理化学研究所 シクロオリゴマンノースおよびその製造法
JPH08843B2 (ja) * 1990-08-01 1996-01-10 理化学研究所 環状ヘテロオリゴ糖及びその合成法
JPH06206905A (ja) * 1993-01-07 1994-07-26 Toppan Printing Co Ltd シクロデキストリン誘導体及びその製造方法
ES2190379B1 (es) * 2001-12-21 2004-11-16 Bioiberica,S.A Procedimiento de preparacion de sales de glucosamina.
KR20120138240A (ko) * 2010-03-24 2012-12-24 아카리오스 비.브이. 치환된 시클로덱스트린 유도체 및 이의 제조방법

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998022795A1 (en) 1996-11-22 1998-05-28 The Regents Of The University Of California Chemical microsensors for detection of explosives and chemical warfare agents
JP2017165725A (ja) 2016-03-09 2017-09-21 国立大学法人鳥取大学 糖の製造方法
US20180362814A1 (en) 2017-06-14 2018-12-20 City University Of Hong Kong Adhesive system, method of manufacture thereof and biological kit comprising same
JP2020138931A (ja) 2019-02-28 2020-09-03 国立大学法人鳥取大学 糖鎖の製造方法、糖鎖合成用のビルディングブロックおよび化合物

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BOURGEAUX E., et al.，General access to asymmetric γ-cyclodextrins for gas chromatographic applications by insertion of a，Tetrahedron: Asymmetry，2000年，Vol.11(20)，p.4189-4205
CHAISE Thomas, et al.，Indirect and direct approaches in the synthesis of a new mono-6-O-benzyl methylated γ-cyclodextrin，Tetrahedron: Asymmetry，2008年，Vol.19(3)，p.348-357

Also Published As

Publication number Publication date
EP4406977A4 (en) 2025-09-10
JP2023045634A (ja) 2023-04-03
EP4406977A1 (en) 2024-07-31
WO2023047790A1 (ja) 2023-03-30
US20240400723A1 (en) 2024-12-05

Similar Documents

Publication Publication Date Title
Zunk et al. A new approach towards the synthesis of pseudaminic acid analogues
SG171990A1 (en) Process for the synthesis of l-fucosyl di- or oligosaccharides and novel 2,3,4 tribenzyl-fucosyl derivatives intermediates thereof
Gening et al. Synthesis of β-(1→ 6)-linked glucosamine oligosaccharides corresponding to fragments of the bacterial surface polysaccharide poly-N-acetylglucosamine
EP3819302B1 (en) Fucosylated chondroitin sulfate oligosaccharide, preparation method therefor, composition thereof and use thereof
JP7670272B2 (ja) 環状オリゴ糖の製造方法、環状オリゴ糖および包接剤
Kamitakahara et al. Block co-oligomers of tri-O-methylated and unmodified cello-oligosaccharides as model compounds for methylcellulose and its dissolution/gelation behavior
Li et al. Synthesis of orthogonally protected L-glucose, L-mannose, and L-galactose from D-glucose
Sato et al. Selective cross-metathesis of cellobiose derivatives with amido-functionalized olefinic structures: A model study for synthesis of cellulosic diblock copolymers
Grin et al. " Click chemistry" in the synthesis of the first glycoconjugates of bacteriochlorin series
FI90777C (fi) Menetelmä sytostaattisesti aktiivisten -rodomysinonijohdannaisten valmistamiseksi
Korchagina et al. Block synthesis of blood group tetrasaccharides B (types 1, 3 and 4)
Pertel et al. The study of the acid-catalyzed reaction between 2-methyl and 2-(2, 2, 2-trichloroethoxy) gluco-[2, 1-d]-2-oxazolines. Synthesis of macrocyclic pseudo-tetrasaccharide derivative of d-glucosamine
EP4424717A1 (en) Novel oligosaccharide, manufacturing intermediate for novel oligosaccharide, and method for manufacturing these
Ali et al. Synthesis of a 2-N, N-dibenzylamino glucopyranosyl trichloroacetimidate glycosyl donor and evaluation of its utility in stereoselective glycosylation
Takeda-Okuda et al. Synthesis of a biotinylated keratan sulfate tetrasaccharide composed of dimeric Galβ1-4GlcNAc6Sβ
Rahman Electrochemical Conversion of Glucosamine Monosaccharides into Variety of Linear and Cyclic Oligosaccharides
JP6455857B2 (ja) 糖鎖化合物の製造方法
JP6198207B2 (ja) 新規糖供与体及びそれを用いた糖鎖の合成方法
JP7417930B2 (ja) 糖鎖の製造方法
Thapa Stereoselective Synthesis of 2, 3-Diamino-2, 3-dideoxy-β-D-mannosides via Anomeric O-Alkylation
Tsuda et al. Preparation of Novel 1, 6-Anhydro-. BETA.-lactose Derivatives for the Synthesis of N-Acetyllactosamine-Containing Oligosaccharides.
HK40109704A (en) Novel oligosaccharide, manufacturing intermediate for novel oligosaccharide, and method for manufacturing these
Wongsrisupphakul Glycosylation of 2-nitro-1-thioglycoside as glycosyl donor
Ventura Toledano et al. Access to n-pentenyl tetra-and pentasaccharide analogues of the antitumor drug PI-88 based on 1, 2-methyl orthoester glycosyl donors
Zhang Chemical Synthesis of Fragments of Galactosaminogalactan and Pel Polysaccharides

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20240412

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20240412

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20250121

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20250305

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20250401

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20250407

R150 Certificate of patent or registration of utility model

Ref document number: 7670272

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150