JP7635558B2 - Liquid Bag Set - Google Patents

Description

The present invention relates to a liquid bag set, a pump tube set, and a tube holder used in blood processing circuits such as renal replacement therapy, simple plasma exchange therapy, and double filtration plasma exchange therapy.

One method of treatment for patients with kidney disorders is a blood processing method called Renal Replacement Therapy (RRT). RRT includes Continuous Renal Replacement Therapy (CRRT) and Intermittent Renal Replacement Therapy (IRRT). For example, in CRRT, blood removed from the patient's body is passed through a filter (continuous slow hemofilter) and dialysis and filtration are performed to remove water from the blood, adjust electrolytes, and remove waste products over a long period of time. An example of a blood processing device used for RRT including CRRT is disclosed in Patent Document 1.

JP 2018-27205 A

In order to perform RRT treatment appropriately, there is a demand for more accurate measurement of the amount of dialysis fluid and/or replacement fluid used and the amount of drained fluid after filtration. To measure these fluids, a measurement sensor is provided in the blood processing device, and multiple bags that store dialysis fluid, etc. and are suspended from the measurement sensor are used, and there is a demand for providing such a measurement system at low cost. Furthermore, blood processing devices are provided with pumps that press multiple tubes filled with each fluid to flow the fluid in the tubes, and there is a demand for improved convenience so that the tubes can be easily and accurately attached to the pump.

The present disclosure therefore aims to provide a liquid bag set, pump tube set, and tube holder that constitute a blood processing circuit for blood purification therapy such as RRT, plasma exchange (PE), or double filtration plasma exchange (DEPP), which solves at least one of the above problems, and which can accurately measure the liquid flowing during treatment, a liquid bag set that allows a measuring system to be provided at a low price, or a pump tube set or tube holder that can improve convenience when attaching the tube.

The liquid bag set according to the first disclosure is used in a blood processing circuit to store liquid flowing through the circuit and is measured by a weight sensor of a blood processing device that controls blood processing by the circuit, and includes a bag for storing liquid and a tube connected at one end to the bag for supplying liquid to the bag or discharging liquid from the bag, the tube having a measured portion that is measured by the weight sensor and a non-measured portion that is not measured by the weight sensor.

This makes it possible to realize a liquid bag set that can accurately measure the liquid flowing through it during treatment. That is, the bags that store each liquid for measurement are connected to tubes through which the liquid flows, and if the measurement is performed including this tube, the amount of liquid used or drained cannot be accurately measured. In contrast, by using the above configuration, the part of the tube that is to be measured is fixedly identified, making it possible to measure the liquid more accurately.

The liquid bag set according to the second disclosure is used in a blood processing circuit to store liquid flowing through the circuit and is weighed by a weight sensor of a blood processing device that controls blood processing by the circuit, and includes a plurality of bags for storing liquid, and a holder that is formed separately from the plurality of bags, supports the plurality of bags, and is attached to the blood processing device so that the holder is weighed together with the plurality of bags by the weight sensor.

This makes it possible to realize a liquid bag set that allows the provision of a weighing system at a low price. That is, the bag that stores the liquid is generally made of synthetic resin, and while it is preferable to use a hard resin with high shape stability for accurate weighing, on the other hand, a bag made of soft resin can be manufactured at a low cost. Therefore, by adopting the above-mentioned configuration, the bag and the holder can be made of materials suitable for each, and accurate weighing and low cost can be achieved at the same time. In addition, since one holder can support multiple bags, they can be set in the device in a unified state, improving the workability when setting. Furthermore, when multiple bags are directly set in the device, there is a possibility that they will be set in the wrong place, but since multiple bags can be supported in the holder before being set in the device, it is possible to prevent mistakes in setting them in the wrong place.

The liquid bag set according to the third disclosure may be configured as the liquid bag set according to the second disclosure, in which the holder has a flat panel and a support arm extending from the panel, and the multiple bags have through holes through which the support arm is inserted.

This allows the bag to be easily supported on the holder, resulting in an easy-to-handle liquid bag set.

The liquid bag set according to the fourth disclosure is used in a blood processing circuit to store liquid flowing through the circuit and is weighed by a weight sensor of a blood processing device that controls blood processing by the circuit, and includes a plurality of bags for storing liquid, and a holder that supports the plurality of bags and is attached to the blood processing device so that the plurality of bags are weighed together with the plurality of bags by the weight sensor, and the plurality of bags include a first bag for storing dialysis fluid or replacement fluid, and a second bag for storing drainage from a filter provided in the blood processing circuit, and the first bag is positioned vertically below the second bag.

As a result, when a large-capacity storage bag is hung on an IV stand or the like and treatment liquid is supplied from it to the first bag, the first bag is located at the bottom, so the treatment liquid can be sent quickly by utilizing the differential pressure, eliminating the need for a separate pump or the like and allowing processes such as priming to be completed quickly.

The liquid bag set according to the fifth disclosure is used in a blood processing circuit to store liquid flowing through the circuit and is weighed by a weight sensor of a blood processing device that controls blood processing by the circuit, and includes a lower bag for storing liquid, a lower tube extending from the lower bag, an upper bag for storing liquid, and an upper tube extending from the upper bag, with the lower tube extending in one direction in the left-right direction and the upper tube extending in the other direction in the left-right direction.

This prevents the tubes extending from each bag from getting close to each other and becoming tangled, and improves visibility of which tube is connected to which bag during the blood processing process. In addition, because the tubes extending from each bag are spaced apart from each other, the operability of the valves can be improved when valves are provided on each tube.

The liquid bag set according to the sixth disclosure is used in a blood processing circuit to store liquid flowing through the circuit, and is weighed by a weight sensor of a blood processing device that controls blood processing by the circuit, and includes a lower bag for storing liquid, a lower tube connection portion provided on the lower bag, and a lower tube extending from the lower tube connection portion, an upper bag for storing liquid, an upper tube connection portion provided on the upper bag, and an upper tube extending from the upper tube connection portion. The lower tube connection part is offset to one side in the left-right direction relative to the lower bag, the lower tube extends from the lower tube connection part to the other side in the left-right direction, and a supported part supported by the blood processing device is provided midway along the lower tube, and the upper tube connection part is offset to the other side in the left-right direction relative to the upper bag, the upper tube extends from the upper tube connection part to one side in the left-right direction, and a supported part supported by the blood processing device is provided midway along the upper tube.

This allows the length of the tube arranged from the tube connection part to the supported part on its side to be relatively large. As a result, even if an unintended external force is applied to the tube, the long tube can absorb the force by deforming, and the effect of the external force on the bag weight measurement can be reduced.

The liquid bag set according to the seventh disclosure is used in a blood processing circuit to store liquid flowing through the circuit and is weighed by a weight sensor of a blood processing device that controls blood processing by the circuit, and includes a bag for storing liquid, a holder that supports the bag and is weighed together with the bag by the weight sensor when attached to the blood processing device, and a tube extending from the bag, and the holder has a notch in the portion that overlaps with the tube when viewed from the front when attached to the blood processing device.

This prevents contact between the holder and the tube, preventing the tube from interfering with the holder due to changes in the tube's position, etc., and thus preventing the weight measurement from being affected.

The pump tube set according to the eighth disclosure is a pump tube set including a plurality of tubes attached to each of a plurality of pumps of a blood processing device, and a tube holder that supports the plurality of tubes, and the tube holder has a structure that allows it to be attached to a holder attachment portion of the blood processing device in a first position, but cannot be attached to the holder attachment portion in a second position other than the first position.

This makes it possible to realize a pump tube set that can improve the convenience of tube attachment. In other words, by supporting multiple tubes together with the tube holder, the entire pump tube set can be made compact and easy to handle. Furthermore, with the above-mentioned configuration, it is possible to realize a pump tube set that prevents the tubes from being attached in the incorrect second position, and encourages the user to attach them in the correct first position, thereby preventing the user from attaching each tube to the wrong pump part.

The pump tube set according to the ninth disclosure is a pump tube set including a plurality of tubes attached to each of a plurality of pumps of a blood processing device, and a tube holder that supports the plurality of tubes, in which a joint is provided at each end of the tubes, and the tube holder is disposed between the two joints.

The tube holder according to the tenth disclosure is a tube holder that supports a plurality of tubes to be attached to each of a plurality of pumps of a blood processing device, the tube holder having a long plate-like holder body, in which three insertion holes through which the three parallel tubes as the plurality of tubes are individually inserted are formed in a line along a long side of the holder body, and in the holder body, a plate-like rib extending in a direction intersecting the main surface of the holder body is provided between the central insertion hole of the three insertion holes and the long side of the holder body.

This allows the width of the long, plate-shaped holder body to be reduced, making the pump tube set more compact, while providing ribs in areas that are weaker than other areas due to the formation of insertion holes, improving the strength of those areas. In particular, the central portion of the holder body in the longitudinal direction is more susceptible to load than the ends, so providing ribs in this portion is effective in improving strength.

The tube holder according to the eleventh disclosure may be the tube holder according to the tenth disclosure, wherein the tube holder is configured to be attached to a holder attachment part provided on the blood processing device, and the rib may form a pressure-receiving part that receives pressure from an operator's finger when attaching the tube holder to the holder attachment part.

As a result, the ribs on the holder body not only increase the strength of the holder body, but also serve as a pressure-receiving portion that is pressed by the fingertips when attaching the holder to the holder attachment portion. Furthermore, if a fitting shape that corresponds to the ribs is provided on the holder attachment portion of the blood processing device, the ribs can also fulfill a positioning function when the tube holder is attached.

The tube holder according to the twelfth disclosure may be the tube holder according to the tenth disclosure, configured such that the tube holder is attached to a holder attachment section provided on the blood processing device, and the holder body may be provided with a recess that, when attached to the holder attachment section, directly faces a movable convex section provided on the blood processing device and biased in a direction approaching the holder body, and forms a moderation mechanism together with the movable convex section.

This allows the user to determine whether the blood processing device is correctly attached to the holder attachment part of the blood processing device based on the clicking sensation generated by the moderation mechanism. Note that the biasing direction of the movable convex part provided on the holder attachment part of the blood processing device may be in any direction as long as it can form a moderation mechanism together with the concave part of the holder body.

The liquid bag set, pump tube set, or tube holder constituting the blood processing circuit according to the present disclosure can realize a liquid bag set that can accurately measure the liquid flowing during treatment, a liquid bag set that allows a measuring system to be provided at a low cost, and a pump tube set or tube holder that can improve convenience when attaching the tube.

FIG. 1 is a schematic diagram showing the overall configuration of a blood treatment circuit for RRT including a liquid bag set and a pump tube set according to a first embodiment. FIG. 2 is a front view of the liquid bag set. FIG. 3 is a perspective view of the fluid bag set. FIG. 4 is an exploded perspective view of the fluid bag set. FIG. 5 is a front view of the holder. FIG. 6 is a partial side view of the holder of FIG. 5 taken along line VI-VI. FIG. 7 is a front view and a side view of the tube holder. FIG. 8 is a perspective view of the pump tube set. FIG. 9 is a perspective view showing a state in which the pump tube set is attached to the pump tube. FIG. 10 is a schematic diagram showing the overall configuration of a blood treatment circuit for RRT including a liquid bag set and a pump tube set according to the second embodiment. FIG. 11 is a schematic diagram showing the configuration when the filter in the circuit of FIG. 10 is turned upside down (upside down). FIG. 12 is a diagram showing the processing liquid set in an expanded state. FIG. 13 is a diagram showing a state in which the tubes in the treatment liquid set of FIG. 12 are bundled together.

(Embodiment 1)
[1. Overall configuration of blood treatment circuit for RRT]
The present invention can be applied to a liquid bag set, a pump tube set, and a tube holder used in a blood processing circuit for blood purification therapy such as renal replacement therapy (RRT), plasma exchange therapy (PE), or double filtration plasma exchange therapy (DEPP). Hereinafter, an embodiment of the present invention will be described by taking a blood circuit for RRT as an example. FIG. 1 is a schematic diagram showing the overall configuration of a blood processing circuit for RRT, and illustrates a blood processing circuit 1 used for HDF (hemodiafiltration) as an example. This blood processing circuit 1 is generally composed of three sets: a blood set 100 on the right side of the figure, a processing liquid set 200 on the left side, and a heating set 300 in the center.

[1-1. Blood set]
The blood set 100 mainly comprises a blood removal line 101, a filter 102, and a blood return line 103. The blood removal line 101 has a flexible tube and connects the patient's blood vessel to the filter 102. A blood pump 110 is provided in the blood removal line 101, and when the blood pump 110 is operated, the patient's blood is sent to the filter 102 through the blood removal line 101.

A saline line 111 joins the blood removal line 101 at the upstream portion (patient side portion) of the blood pump 110. A bag 112 containing saline is connected to the saline line 111, and saline is supplied to the blood removal line 101 during priming. A drug line 113 joins the blood removal line 101 at the upstream portion of the blood pump 101 and downstream portion (filter side portion) of the joining point of the saline line 111. A syringe 114 containing a drug such as an anticoagulant is connected to the drug line 113, and the anticoagulant is injected through the drug line 113 into the blood passing through the blood removal line 101.

In the blood removal line 101, an arterial pressure chamber 115 consisting of a drip chamber is interposed in the downstream portion of the blood pump 110. The pressure of the blood in the blood removal line 101 can be measured by connecting a pressure monitor (not shown) to a pressure measurement line 701 extending from this arterial pressure chamber 115 via a patient protection filter 701A consisting of a hydrophobic filter. In addition, a pre-dilution line 116 extends from the arterial pressure chamber 115, and by connecting a bag containing replacement fluid such as an electrolyte solution to this line, the blood passing through the blood removal line 101 can be pre-diluted with the replacement fluid.

The filter 102 includes a cylindrical case 120 and a filter 121 housed in the case 120. The filter 121 is, for example, configured by bundling a number of hollow fibers. The case 120 includes a blood inlet port 122 provided at one end, a blood outlet port 123 provided at the other end, a dialysate port 124 provided at the periphery near the one end, and a drainage port 125 provided at the periphery near the other end. The downstream end of the blood removal line 101 described above is connected to the blood inlet port 122.

The upstream end of the blood return line 103 is connected to the blood outlet port 123 of the case 120. The blood return line 103 has a flexible tube and connects between the filter 102 and the patient's blood vessel. A mixing chamber 130 is interposed in the middle of the blood return line 103, and replacement fluid sent from the treatment fluid set 200 described below can be supplied to the returned blood in this mixing chamber 130. In addition, a pressure measurement line 702 extends from the mixing chamber 130 and is connected to a pressure monitor (not shown) via a patient protection filter 702A.

[1-2. Processing liquid set]
The treatment fluid set 200 mainly includes a supply fluid line 201, a pump unit 202, and a drainage line 203. The supply fluid line 201 includes a storage bag 210 for storing a liquid common to the dialysis fluid and replacement fluid, a common line 211 having one end connected to the storage bag 210, and a first liquid bag 212 for measurement connected to the other end of the common line 211 and for temporarily storing the liquid. As will be described later in detail, the first liquid bag 212 constitutes a bag according to the present invention whose weight is measured by a weight sensor provided in the blood treatment device 400.

The supply fluid line 201 further includes a dialysate line 213 and a post-fluid replacement line 214. That is, the common line 211 is branched at two points, and the dialysate line 213 and the post-fluid replacement line 214 extend from each branch. Of these, the post-fluid replacement line 214 branches off from a position closer to the first fluid bag 212 along the common line 211 than the dialysate line 213.

The drainage line 203 has a recovery line 230, one end of which is connected to the drainage port 125 of the filter 102, and a second liquid bag 231 for measuring, which is connected to the other end of the recovery line 230 and temporarily stores the drainage. The drainage line 203 further has a waste line 232 extending from a branch midway through the recovery line 230, and a tank 233 located at the downstream end of the waste line 232. Of these, the second liquid bag 231, together with the above-mentioned first liquid bag 212, constitutes a bag according to the present invention whose weight is measured by a weight sensor provided in the blood processing device 400.

All of the lines 201, 203 (including the lines 211, 213, 214, 230, and 232 that compose them) of the treatment liquid set 200 are made of flexible tubes. In addition, a pressure measurement line 703 extends from the middle of the recovery line 230 and is connected to a pressure monitor (not shown) via a patient protection filter 703A.

The pump unit 202 includes, for example, three finger pumps 221 to 223, which are arranged vertically on the side of the blood processing device 400. The upper finger pump 221 is set with the middle part of the post-fluid replacement line 214 (pressurized part 601a: see FIG. 8), the central finger pump 222 is set with the middle part of the dialysis fluid line 213 (pressurized part 601a: see FIG. 8), and the lower finger pump 223 is set with the middle part of the recovery line 230 (pressurized part 601a: see FIG. 8). When setting the lines 213, 214, and 230 in the pump unit 202, a tube holder 224 is used to integrally support the lines 213, 214, and 230 in order to improve the convenience of the work. The tube holder 224 will be described in detail later.

[1-3. Heating set]
The heating set 300 includes a dialysate heating line 301 and a post-replacement fluid heating line 302. The upstream end of the dialysate heating line 301 is connected to the downstream end of the dialysate line 213, and the downstream end of the dialysate heating line 301 is connected to the dialysate port 124 of the filter 102. The upstream end of the post-replacement fluid heating line 302 is connected to the downstream end of the post-replacement fluid line 214, and the downstream end of the post-replacement fluid heating line 302 is connected to the mixing chamber 130.

The heating set 300 further includes a dialysis fluid heater 303 and a post-replacement fluid heater 304. These heaters 303, 304 are provided in the blood processing device 400 and generate heat according to the power supplied. Therefore, the dialysis fluid heater 303 heats the dialysis fluid flowing through the dialysis fluid heating line 301, and the post-replacement fluid heater 304 heats the replacement fluid flowing through the post-replacement fluid heating line 302.

[1-4. Operation of the blood treatment circuit]
The blood treatment circuit 1 generally operates as follows. That is, when the blood pump 110 is driven in the blood set 100, blood drawn from the patient is sent along the blood removal line 101 to the filter 102 while a replacement fluid, an anticoagulant, etc. are injected. The blood sent to the filter 102 is filtered by the filter 121, and the generated drainage fluid is collected in a tank 233 through the drainage line 203 of the treatment fluid set 200. Meanwhile, some components in the blood sent to the filter 102 diffuse into the dialysis fluid supplied from the treatment fluid set 200 through the dialysis fluid port 124, and this is also collected in the tank 233 through the drainage line 203 of the treatment fluid set 200. Then, the blood that has been filtered and diffused in the filter 102 is returned to the patient through the blood return line 103 while a replacement fluid is supplied in the mixing chamber 130 on the way.

In this blood processing circuit 1, the liquid in the storage bag 210 is temporarily stored in the first liquid bag 212 and then supplied to the filter 102 or the mixing chamber 130. The liquid stored in the first liquid bag 212 is weighed by a weight sensor provided in the blood processing device 400, thereby measuring the amount of liquid supplied. The drained liquid collected from the filter 102 is also temporarily stored in the second liquid bag 231 and then discarded in the tank 233. The drained liquid stored in the second liquid bag 231 is weighed by a weight sensor provided in the blood processing device 400, thereby measuring the amount of drained liquid.

[2. Liquid bag set]
The blood processing circuit 1 according to this embodiment includes a liquid bag set 500 for accurately measuring the weight of the liquid stored in the first liquid bag 212 and the second liquid bag 231. This liquid bag set 500 can be used in the blood processing circuit 1 for renal replacement therapy (RRT) such as HDF described above, and is a liquid bag set that stores liquid (dialysis fluid, post-replacement fluid, drainage fluid, etc.) flowing through this blood processing circuit 1 and is weighed by a weight sensor provided in the blood processing device 400 that controls blood processing by the blood processing circuit 1. The liquid bag set 500 will be described below.

2 is a front view of the liquid bag set 500, FIG. 3 is a perspective view of the liquid bag set 500, and FIG. 4 is an exploded perspective view of the liquid bag set 500. The liquid bag set 500 has a bag unit 501 and a bag holder 502 that supports the bag unit 501. In addition to the first liquid bag 212 and the second liquid bag 231, the bag unit 501 has at least a part of the common line 211 connected to the first liquid bag 212 and at least a part of the recovery line 230 connected to the second liquid bag 231. Hereinafter, when referring to matters common to the first liquid bag 212 and the second liquid bag 231, both may be referred to as liquid bags 240.

The bag holder 502 detachably supports the bag unit 501 including each liquid bag 240. When the bag holder 502 is attached to the blood processing device 400, its weight is measured together with the bag unit 501. To attach the bag holder 502 to the blood processing device 400, the blood processing device 400 is provided with a holder hanger 503. The configurations of the bag unit 501, bag holder 502, and holder hanger 503 are described in more detail below. In the following description, the up and down (vertical up and down), left and right, and front and back directions are used when the liquid bag set 500 is attached to the blood processing device 400.

[2-1. Bag unit]
The liquid bag 240 of the bag unit 501 has a bag body 241 having a liquid storage chamber 242 therein, the bag body 241 being made of two generally rectangular flexible films sealed by welding the peripheral portions of the films together, for example. A flange 243 is formed on the upper side 241u of the bag body 241, the flange 243 being wide and extending to the left and right, and through holes 244 are provided near each of the left and right ends of the flange 243. These through holes 244 are slit-shaped with a slit length D1 (see FIG. 4) whose longitudinal direction is along the left-right direction.

The bag body 241 has a tube connection part 245 that connects the inside and outside of the bag body 241 on the lower side 241d that faces the flange 243. The tube connection part 245 of the first liquid bag 212 is located to the right of the center in the front view, and the tube connection part 245 of the second liquid bag 231 is located to the left of the center in the front view (see FIG. 2). In addition, the lower side 241d of the bag body 241 has a gentle slope that slopes downward from the side end toward the tube connection part 245, and the inner bottom surface of the storage chamber 242 also slopes downward toward the tube connection part 245 in accordance with this slope.

A common line (lower tube) 211 is connected to the tube connection part (lower tube connection part) 245 of the first liquid bag (lower bag) 212. This common line 211 has, in order from the side closest to the tube connection part 245, a first tube 250, an L-shaped joint 251, a second tube 252, an L-shaped joint 253, and a third tube 254.

Specifically, the upper end of the first tube 250, which is short and extends in the vertical direction, is connected to the tube connection part 245, and the upper end of the L-shaped joint 251 is connected to the lower end of the first tube 250. The right end of the second tube 252, which extends in the horizontal direction, is connected to the left end of the L-shaped joint 251, and the left end of the second tube 252 is connected to the left end of the second L-shaped joint 253. Furthermore, the upper end of the third tube 254 is connected to the lower end of the L-shaped joint 253. In this way, in the first liquid bag 212, the tube connection part 245 is biased to the right side of the bag body 241, and the common line 211 (particularly the second tube 252) connected to the tube connection part 245 extends to the opposite left side. The L-shaped joints 251 and 253 are made of a synthetic resin that is harder than the tubes 250, 252, and 254.

A recovery line (upper tube) 230 is connected to the tube connection part (upper tube connection part) 245 of the second liquid bag (upper bag) 231. This recovery line 230 has, in order from the side closest to the tube connection part 245, a first tube 260, an L-shaped joint 261, a second tube 262, an L-shaped joint 263, and a third tube 264.

Specifically, the upper end of the first tube 260, which is short and extends in the vertical direction, is connected to the tube connection part 245, and the upper end of the L-shaped joint 261 is connected to the lower end of the first tube 260. The left end of the second tube 262, which extends in the horizontal direction, is connected to the right end of the L-shaped joint 261, and the right end of the second tube 262 is connected to the right end of the second L-shaped joint 263. Furthermore, the upper end of the third tube 264 is connected to the lower end of the L-shaped joint 263. In this way, in the second liquid bag 231, the tube connection part 245 is biased to the left side of the bag body 241, and the recovery line 230 (particularly the second tube 262) connected to the tube connection part 245 extends to the opposite right side. The L-shaped joints 261 and 263 are made of a synthetic resin that is harder than the tubes 260, 262, and 264.

As can be seen from the above description and FIG. 2, in this embodiment, the first liquid bag 212 and the portion of the common line 211 near the first liquid bag 212, and the second liquid bag 231 and the portion of the recovery line 230 near the second liquid bag 231 are configured symmetrically. However, the configuration of the two is not limited to this, and they may be asymmetrical with each other. In addition, the common line 211 extends to the left from the first liquid bag 212, and the recovery line 230 extends to the right from the second liquid bag 231, but the common line 211 and the recovery line 230 may be configured to extend in the same direction from each liquid bag 212, 231.

[2-2. Bag holder]
Next, the bag holder 502 will be described with reference to the front view of Fig. 5 and the partial side view of Fig. 6. The bag holder 502 includes a flat panel 510 and a support arm 511 extending from the panel 510. The bag holder 502 includes a first holder portion 512 located on the lower side to support the first liquid bag 212 and a second holder portion 513 located on the upper side to support the second liquid bag 231, and these are integrated into one structure. Hereinafter, when matters common to the first holder portion 512 and the second holder portion 513 are mentioned, both of them may be referred to as the holder portion 520. Note that the bag holder 502 may be configured differently from that shown in the drawings, such that the upper second holder portion 513 supports the first liquid bag 212 and the lower first holder portion 512 supports the second liquid bag 231.

The holder section 520 has a panel section 521 that is generally rectangular and made of a synthetic resin that is harder than the bag body 241 of the liquid bag 240. Specific materials for the bag body 241 can be selected from, for example, PVC (polyvinyl chloride resin), EVA (ethylene-vinyl acetate copolymer resin), PE (polyethylene resin), TPU (thermoplastic polyurethane), and styrene-based elastomer. In addition, PVC is preferable among these materials in terms of compatibility with the connection between the bag body 241 and the tubes that constitute each line 211, 230 and price. Specific materials for the holder section 520 can be selected from, for example, PET (polyethylene terephthalate), A-PET (amorphous PET), C-PET (crystallized PET), G-PET (glycol modified PET), PS (polystyrene resin), and PP (polypropylene resin). In addition, A-PET is preferable among these materials in terms of the overall rigidity of the holder section 520, elasticity that does not break when the support arm 511 is bent, transparency of the holder section 520, and price.

The panel portion 521 has a thick portion 522 and a thin portion 523, and the thick portion 522 is positioned so as to surround the thin portion 523, forming a frame shape. Therefore, the thick portion 522 ensures that the panel portion 521 has sufficient rigidity to maintain a flat plate shape. Meanwhile, support arms 511 that are inserted into the through holes 244 of the liquid bag 240 are provided near the left and right ends of the upper side of the panel portion 521 so as to extend upward.

The support arm 511 has a base end 530 located on the base end side (lower side) in the extension direction (upward), and a tip end 531 located on the tip side (upper side) of the extension direction relative to the base end 530. The base end 530 has a rectangular shape with rounded corners, and the tip end 531 is connected to its upper side. More specifically, the tip end 531 has a smaller width dimension in the left-right direction than the base end 530, and in the right support arm 511, the tip end 531 is connected to the upper side of the base end 530, moving to the left, and in the left support arm 511, the tip end 531 is connected to the upper side of the base end 530, moving to the right. Furthermore, a cut portion 532 is formed in the lower end portion of the tip end 531 in the width direction (left-right direction). This cut portion 532 opens outward in the left-right direction in the holder portion 520. In other words, the right support arm 511 opens to the right, and the left support arm 511 opens to the left.

The lower end of the support arm 511 is connected to a thick portion 522 on the upper side of the panel portion 521, and the support arm 511 is formed to be thinner than the thick portion 522. The support arm 511 can be bent forward at its lower end relative to the panel portion 521 by the operation of a person's fingers. Therefore, when the support arm 511 is biased forward, the base end portion 530 and the tip end portion 531 are bent forward together. The support arm 511 bent forward in this manner is inserted into the through hole 244 of the liquid bag 240, and the holder portion 520 supports the upper portion of the liquid bag 240 (see FIG. 3).

Here, as shown in FIG. 5, the base end 530 of the support arm 511 has a width dimension D2. The tip end 531 of the support arm 511 has a maximum width dimension D3 in the portion without the notch 532, and a minimum width dimension D4 in the portion where the notch 532 is formed. These dimensions D2, D3, and D4 have a relationship of D2>D1=D3>D4 with the slit length D1 of the through hole 244 of the liquid bag 240. Therefore, the support arm 511 can insert only its tip end 531 into the through hole 244 of the liquid bag 240, and can engage with the through hole 244 at the notch 532. However, the magnitude relationship of each dimension is not limited to this, and for example, the maximum width dimension D3 of the tip end 531 may be set slightly smaller than the slit length D1 of the through hole 244.

The panel portion 521 of the holder portion 520 has a panel extension portion 540, part of whose lower end extends further downward, and a joint holder 541 is provided on the front surface of this panel extension portion 540. The joint holder 541 has a protrusion portion 542 that protrudes forward from the panel extension portion 540, and this protrusion portion 542 has a generally rectangular shape when viewed from the front. The joint holder 541 also has a fitting groove 543 that forms a recess in the protrusion portion 542 and extends in an L-shape when viewed from the front.

The fitting groove 543 of the joint holder 541 of the lower first holder part 512 opens at the left-right center of the upper surface of the rectangular protrusion 542 and at the top-bottom center of the left surface, forming an L-shaped groove (an inverted L-shape) connecting these two openings. That is, the fitting groove 543 extends downward from the left-right center of the upper surface of the protrusion 542, turns around approximately near the center of the protrusion 542, extends to the left, and reaches the opening at the top-bottom center of the left surface. The panel extension part 540 and the joint holder 541 of the first holder part 512 are provided to the right of the left-right center with respect to the panel part 521.

As shown in FIG. 3, the joint holder 541 of the first holder part 512 supports the L-shaped joint 251 connected to the first liquid bag 212 via the first tube 250 by fitting it into the fitting groove 543. As described above, the joint holder 541 is biased to the right side of the panel part 521, so a space (notch) 540a is formed on the left side of the joint holder 541. When the first liquid bag 212 is supported by the first holder part 512, this space 540a overlaps with the common line 211 (particularly the second tube 252) in a front view (see FIGS. 2 and 3). This prevents the bag unit 501 and the bag holder 502 from interfering with each other on the common line 211, which would affect the weight measurement.

The fitting groove 543 of the joint holder 541 of the upper second holder part 513 opens at the left-right center of the top surface of the rectangular protrusion 542 and at the top-bottom center of the right surface, forming an L-shaped groove connecting these two openings. That is, the fitting groove 543 extends downward from the left-right center of the top surface of the protrusion 542, turns approximately near the center of the protrusion 542, extends to the right, and reaches the opening at the top-bottom center of the right surface. Note that the panel extension part 540 and the joint holder 541 of the second holder part 513 are provided on the left side of the left-right center with respect to the panel part 521, in contrast to the case of the first holder part 512.

As shown in FIG. 3, the joint holder 541 of the second holder portion 513 supports the L-shaped joint 261 connected to the second liquid bag 231 via the first tube 260 by fitting it into the fitting groove 543. As described above, the joint holder 541 is biased to the left side of the panel portion 521, so a space (notch) 540a is formed on the right side of the joint holder 541. This space 540a overlaps with the recovery line 230 (particularly the second tube 262) in a front view when the second liquid bag 231 is supported by the second holder portion 513 (see FIGS. 2 and 3). This prevents the bag unit 501 and the bag holder 502 from interfering with each other in the recovery line 230, which would affect the weight measurement.

As shown in FIG. 6, the groove width dimension D5 of the inside 543a of the fitting groove 543 is almost constant in the depth direction of the groove, but the front opening end 543b has an opening dimension D6 that is slightly narrower than dimension D5. This prevents the L-shaped joints 251, 261 from falling off after they are fitted into the fitting groove 543. Note that this configuration in which the opening end 543b is narrower than the inside 543a may be provided over the entire length of the fitting groove 543, or may be provided only in part of it. If provided only in part, it is preferable to provide it only in part of each of the parts extending in the vertical direction and the horizontal direction when the fitting groove 543 is viewed from the front.

The lower first holder part 512 and the upper second holder part 513 are connected and integrated by the panel extension part 540 of the second holder part 513. That is, the panel extension part 540 extending downward from the panel part 521 of the upper second holder part 513 has its lower end connected to the upper end of the panel part 521 of the lower first holder part 512.

The panel section 521 of the upper and lower holder sections 520 (first holder section 512 and second holder section 513) has upper supported sections 550 that protrude outward in a rectangular shape from the upper end of the left and right side ends. The upper supported sections 550 are made of the thick section 522 of the panel section 521, and are supported by the holder hanger 503 as described below. Furthermore, the left and right parts of the lower end of the panel section 521 of the lower first holder section 512, which are separated by the panel extension section 540, form the lower supported sections 551. The lower supported sections 551 are also made of the thick section 522 of the panel section 521, and are supported by the holder hanger 503. The lower edges of the left and right lower supported sections 551 are inclined so as to move downward as they approach the center (in other words, as they approach the panel extension section 540).

As described above, the liquid bag set 500 is composed of a bag unit 501 and a bag holder 502. The bag unit 501 and the bag holder 502 are constructed separately, and the bag unit 501 is supported by the relatively hard bag holder 502, so that they are separable from each other. However, the bag unit 501 and the bag holder 502 may not be separable, and specifically, they may be constructed separately and then fixed to each other by welding or fastening to form an integrated unit.

[2-3. Holder hanger]
4, the holder hanger 503 is a plate made of hard synthetic resin, and its shape in front view has a contour similar to that of the panel 510 (including the upper and lower panel portions 521 and the upper and lower panel extension portions 540) of the bag holder 502. The holder hanger 503 is fixedly attached to, for example, the side wall portion of the blood processing device 400 by a fastening means such as a screw, and the liquid bag set 500 is suspended from it.

More specifically, the holder hanger 503 has a flat main body plate 560. This main body plate 560 has a first plate 561 corresponding to the lower first holder part 512, and a second plate 562 corresponding to the upper second holder part 513. Furthermore, the holder hanger 503 has a lower support hook 563 and an upper support hook 564 provided on this main body plate 560.

The lower first plate 561 of the main body plate 560 has a rectangular portion 561a corresponding to the panel portion 521 of the first holder portion 512, and an extension portion 561b extending downward from the rectangular portion 561a and corresponding to the panel extension portion 540 of the first holder portion 512. The extension portion 561b is connected to a position toward the right of the center of the lower end of the rectangular portion 561a. Lower support hooks 563 are provided on the left and right of the extension portion 561b at the lower end of the rectangular portion 561a, and a central support hook 564 is provided at the lower end of the extension portion 561b.

The lower support hook 563 has a hook shape with a gap 563a that opens upward. Specifically, the lower support hook 563 has an L-shaped folded portion 563b in a side view, which is like a horizontally long plate material extending from the lower end of the rectangular portion 561a folded forward and then folded upward, and the lower and front sides of the gap 563a are surrounded by this folded portion 563b. The first holder portion 512 is supported from below by the lower support hook 563, as the lower supported portion 551 formed at the lower end of the panel portion 521 is fitted into the gap 563a. In addition, the left and right lower support hooks 563 are inclined downward as they approach the center (in other words, as they approach the extension portion 561b). Therefore, the lower support hook 563 makes line contact with the lower edge of the lower supported part 551 to stably support the first holder part 512, and the folded shape prevents the lower supported part 551 from coming off the lower support hook 563.

The central support hook 564 has a hook shape with a gap 564a that opens upward. Specifically, the central support hook 564 has a folded portion 564b that is a horizontally long plate material extending from the lower end of the extension portion 561b folded forward and then folded upward, and a folded portion 564c that is a vertically long plate material extending from the right end of the extension portion 561b folded forward and then folded back to the left. These folded portions 564b and 564c are connected to each other and form an L-shape (an inverted L-shape) when viewed from the front, surrounding the lower, right, and front sides of the gap 564a. The first holder portion 512 is supported from below by the central support hook 564 as the panel extension portion 540 and the joint holder 541 are fitted into the gap 564a.

The upper second plate 562 of the main body plate 560 has a rectangular portion 562a corresponding to the panel portion 521 of the second holder portion 513, and an extension portion 562b extending downward from the rectangular portion 562a and corresponding to the panel extension portion 540 of the second holder portion 513. The extension portion 562b is connected to a position toward the left of the center of the lower end of the rectangular portion 562a, and its lower end is also connected to the upper end of the first plate 561. Therefore, the first plate 561 and the second plate 562 are integrally connected by the extension portion 562b.

Upper support hooks 565 are provided to protrude forward from the upper ends of the left and right side ends of the rectangular portion 561a of the first plate 561 and the upper ends of the left and right side ends of the rectangular portion 562a of the second plate 562. The upper support hooks 565 are folded back so that they extend forward from the side ends of the rectangular portions 561a and 562a and then extend upward, forming an L-shape in side view. These upper support hooks 565 support the upper supported portions 550 protruding from the side ends of the upper and lower panel portions 521 from below. The distance between the left and right upper support hooks 565 is set to be slightly larger than the left-right dimension of the corresponding panel portion 521.

As shown in Figures 2 to 4, the blood processing device 400 has two joint supports 570, 571 near the lower first plate 561. One joint support 570 is provided near the lower left of the first plate 561, and the other joint support 571 is provided near the upper right of the first plate 561. These joint supports 570, 571 are provided on the side walls of the blood processing device 400, similar to the holder hanger 503, and are not subject to measurement by the weight sensor provided in the blood processing device 400.

The two L-shaped joints 253, 263 of the bag unit 501 are supported by these joint support parts 570, 571. In other words, the joint support parts 570, 571 support the common line 211 or the recovery line 230 at a position offset laterally from the tube connection part 245 of each liquid bag 240. Note that each of the joint support parts 570, 571 may be configured to fixedly support the L-shaped joints 253, 263 to the blood processing device 400, and the specific configuration is not limited, such as a configuration in which the L-shaped joints 253, 263 are gripped or bound with wire.

The holder hanger 503 as described above is attached to the blood processing device 400 by fastening means such as screws passed through a plurality of through holes 566 formed in the main body plate 560. When the liquid bag set 500 is supported by the holder hanger 503 attached to the blood processing device 400, the weight of the liquid bag set 500 can be measured by a weight sensor provided in the blood processing device 400.

[2-4. Support form of liquid bag set]
A description will be given of a mode in which the liquid bag set 500 (bag unit 501 and bag holder 502) is supported on the blood processing apparatus 400 via the holder hanger 503. First, the bag unit 501 is supported by the bag holder 502. At this time, each liquid bag 240 of the bag unit 501 is empty.

Specifically, each support arm 511 of the bag holder 502 is folded forward and passed through the corresponding through-hole 244. That is, the tip 531 of the support arm 511 is passed through the through-hole 244, and the left and right outer parts of the through-hole 244 are clamped by the notch 532. At this time, since the width dimension D2 of the base end 530 of the support arm 511 is larger than the slit length D1 of the through-hole 244, only the tip 531 of the support arm 511 can be passed through the through-hole 244. As a result, the flange portion 243 at the upper end of the liquid bag 240 is supported in a state where it is separated forward by a predetermined dimension (the vertical dimension of the base end 530) from the bag holder 502. Therefore, the liquid bag 240 is not excessively compressed by the bag holder 502, so that a large amount of liquid can be stored in the storage chamber 242.

Furthermore, the L-shaped joints 251, 261 closer to each liquid bag 240 in the bag unit 501 are supported by each joint holder 541 of the bag holder 502. That is, the lower L-shaped joint 251 fits into the fitting groove 543 of the joint holder 541 of the first holder part 512 and is sandwiched between the two protrusions 542. Similarly, the upper L-shaped joint 261 fits into the fitting groove 543 of the joint holder 541 of the second holder part 513 and is sandwiched between the two protrusions 542. At this time, as already mentioned, the opening dimension D6 of the opening end 543b of each fitting groove 543 is smaller than the groove width dimension D5 of the interior 543a, so that the sandwiched L-shaped joints 251, 261 are prevented from falling off.

In this way, each liquid bag 240 is supported at three points on the bag holder 502, two at the top and one at the bottom. As can be seen from Figures 3 and 4, for example, the vertical separation dimension between the lower support arm 511 and the joint holder 541 in the bag holder 502 is smaller than the vertical separation dimension between the through hole 244 and the L-shaped joint 251 for the lower liquid bag 240. In other words, the separation dimension between the upper and lower support positions for one liquid bag 240 in the bag holder 502 is smaller than the separation dimension between the upper and lower supported positions of the liquid bag 240. Therefore, the liquid bag 240 supported by the bag holder 502 is not subjected to excessive tension in the vertical direction and is partially bent forward. This reduces the stress acting on the liquid bag 240, and requires less liquid pressure when filling the storage chamber 242, allowing the liquid to be stored smoothly.

As described above, each liquid bag 240 is supported by the bag holder 502, and the bag unit 501 and the bag holder 502 are integrated to form the liquid bag set 500. Next, this liquid bag set 500 is supported by the holder hanger 503.

Specifically, a total of four upper supported parts 550 of the first holder part 512 and the second holder part 513 are suspended from the left and right upper support hooks 565 of the panel hanger 503. At the same time, the left and right lower supported parts 551 of the lower first holder part 512 are suspended from the left and right lower support hooks 563 of the panel hanger 503, and the panel extension part 540 and the joint holder 541 of the first holder part 512 are suspended from the central support hook 564 of the panel hanger 503.

Furthermore, the joint support part 570 of the blood processing device 400 supports the L-shaped joint 253 in the common line 211 connected to the first liquid bag 212, and the joint support part 571 supports the L-shaped joint 263 in the recovery line 230 connected to the second liquid bag 230. As a result, the bag unit 501 is divided by the L-shaped joints 253, 263 into a measuring part A that is measured by the weight sensor of the blood processing device 400 and a non-measuring part B that is not measured. The measuring part A includes the liquid bag 240, the first tubes 250, 260, the L-shaped joints 251, 261, and the second tubes 252, 262. The non-measuring part includes the L-shaped joints 253, 263 and the third tubes 254, 264.

In this way, by supporting the common line 211 and the recovery line 230 in a fixed manner in the blood processing device 400 in a portion that is not measured by the weight sensor, the portion A measured by the weight sensor and the portion B not measured are clearly separated, so that the liquid bag 240 can be accurately measured even if the posture of each line 211, 230 changes. In addition, the liquid bag 240 and the bag holder 502 are separate, and suitable materials can be selected for each, so that a liquid bag set 500 can be realized that can achieve both accurate measurement and low cost.

[3. Pump Tube Set]
1, the blood processing circuit 1 according to this embodiment includes a tube holder 224 that integrally supports the lines 213, 214, and 230 in order to improve the convenience of the work when the lines 213, 214, and 230 are set in the pump unit 202. A pump tube set 600 consisting of the tube holder 224 and the lines 213, 214, and 230 supported by the tube holder 224 will be described in detail with reference to Figures 7 to 9. In the following, each tube that constitutes the part of the lines 213, 214, and 230 included in the pump tube set 600 will be referred to as a tube 601.

Figure 7 shows three views of the tube holder 224; the left side shows the tube holder 224 as seen from the right side, the center shows the tube holder 224 as seen from the rear, and the right side shows the tube holder 224 as seen from the left side. As shown in Figure 7, the tube holder 224 has a holder body 602 that is long in the vertical direction and has a plate-like (or band-like) shape, and a plate-like rib 603 that protrudes from the holder body 602. The holder body 602 has a length L that corresponds to the vertical dimension of the pump unit 202, and a width dimension W1 that is larger than the diameter of the tube 601. The holder body 602 is disposed with its main surface facing left and right.

The holder body 602 has an upper end and a lower end formed into an arc-shaped outline, and has three insertion holes 604 corresponding to the lines 213, 214, and 230. The three insertion holes 604 are aligned along the long side of the holder body 602 and form a support portion that individually supports each tube 601. That is, the central insertion hole 604 supports the tube 601 of the dialysis fluid line 213, the upper insertion hole 604 supports the tube 601 of the post-fluid replacement line 214, and the lower insertion hole 604 supports the tube 601 of the recovery line 230. Therefore, each insertion hole 604 has a diameter W2 that is the same as or slightly smaller than the diameter of the tube 601.

Each insertion hole 604 is located on one side of the width direction of the holder body 602 (rear in FIG. 7). That is, the center of each insertion hole 604 is located rearward of the center of the width direction of the holder body 602. Furthermore, a notch 605 is formed in the edge of the long side of the rear side of the holder body 602 at a location corresponding to each insertion hole 604. Therefore, each insertion hole 604 is partially opened rearward by the notch 605, and the flexible tube 601 can be fitted into the insertion hole 604 through this notch 605.

In the holder body 602, a rib 603 is provided between the central through hole 604 and the edge of the long side of the front of the holder body 602. In this embodiment, the rib 603 is provided so as to be flush with the edge of the long side of the front of the holder body 602 in a side view. This rib 603 is a long plate in the vertical direction, and its width direction coincides with the direction intersecting with the main surface of the holder body 602 (the direction perpendicular in FIG. 7). The central part of the holder body 602 in the vertical direction tends to have low strength because the remaining part has a small width dimension due to the presence of the central through hole 604, but the strength of this part is compensated for by the rib 603.

The rib 603 has a rib 603a extending leftward from the left main surface of the holder body 602, and a rib 603b extending rightward from the right main surface of the holder body 602, and the two ribs 603a, 603b are aligned in the vertical direction. On the other hand, the central position of the longitudinal direction of the rib 603 does not match the vertical position of the center of the central insertion hole 604, and is located above the center of the central insertion hole 604.

The left rib 603a is formed so that the thickness is the same throughout. On the other hand, the right rib 603b has an upper portion 610 that is the same thickness as the left rib 603a, and a lower portion 611 that is smaller in thickness. More specifically, in the right rib 603b, the upper portion 610 and the lower portion 611 are flush with each other, but the rear surface of the lower portion 611 is offset forward from the rear surface of the upper portion 610. The lower portion 611 of the rib 603b is located in front of the central through hole 604, and the upper portion 610 is located above the through hole 604. In this way, by offsetting the rear surface of the lower portion 611 adjacent to the through hole 604 in the rib 603b forward (away from the through hole 604), interference with the joint 620 (see FIG. 8) of the tube 601 inserted through the through hole 604 is avoided.

As shown in FIG. 8, in the pump tube set 600, the tube holder 224 supports three tubes 601 that form the three lines 213, 214, and 230. Of these, the tube 601 that forms the dialysate line 213 has joints 620 attached to both ends, and is connected to the other tubes that form the dialysate line 213 via these joints 620. The tube 601 that forms the post-fluid replacement line 214 also has joints 620 attached to both ends, and is connected to the other tubes that form the post-fluid replacement line 214 via these joints 620. The tube 601 that forms the recovery line 230 also has joints 620 attached to both ends, and is connected to the other tubes that form the recovery line 230 via these joints 620.

The tube holder 224 supports each tube 601 at a position on the left side near the right joint 620. The joint 620 has a smaller diameter than the notch 605 of the through hole 604 of the tube holder 224 and the diameter (W2) of the through hole 604.

The two joints 620 attached to both ends of each tube 601 are colored differently. For example, in this embodiment, in the dialysis fluid line 213, the joint 620 on the left side of the tube 601 (upstream side in the flow direction of the dialysis fluid) is colored red, and the joint 620 on the right side (downstream side) is transparent. In the post-refill line 214, the joint 620 on the left side of the tube 601 (upstream side in the flow direction of the post-refill fluid) is colored red, and the joint 620 on the right side (downstream side) is transparent. In the recovery line 230, the joint 620 on the left side of the tube 601 (downstream side in the flow direction of the drainage fluid) is transparent, and the joint 620 on the right side (upstream side) is colored red. In each tube 601, a predetermined portion between the left joint 620 and the tube holder 224 forms a pressurized portion 601a that is pressurized by the pump unit 202.

Figure 9 is a perspective view of the pump tube set 600 placed slightly away from the pump unit 202. As shown in this figure, the pump unit 202 has three finger pumps 221 to 223, which are arranged from the top to the bottom, and these clamp and pressurize the pressurized portion 601a of each tube 601, thereby sending the liquid in the tube 601 in a predetermined direction. In this embodiment, when the upper finger pump 221 is driven, the replacement fluid in the tube 601 of the post-replacement fluid line 214 is sent to the right in the figure, when the central finger pump 222 is driven, the dialysis fluid in the tube 01 of the dialysis fluid line 213 is sent to the right in the figure, and when the lower finger pump 223 is driven, the drainage fluid in the tube 601 of the recovery line 230 is sent to the left in the figure. In addition, the pump unit 202 has a joint mounting part 630 on the left side of the finger pumps 221 to 223, and a holder mounting part 640 on the right side.

Three left-side joint mounting parts 630 are provided corresponding to the left-side joints 620 of each tube 601. Each joint mounting part 630 has a recessed portion that opens forward, and is shaped to match the outline of the joint 620 when viewed from the front. The right-side holder mounting part 640 has a recessed groove 641 that is long in the vertical direction, and this groove 641 is sandwiched between left and right wall parts 642, 643. The left-side wall part 642 has notches 642a corresponding to the three tubes 601 supported by the tube holder 224, and the right-side wall part 643 has notches 643a corresponding to the joints 620 attached to the right ends of the tubes 601. These notches 642a, 643a open left and right and forward.

Furthermore, rib fitting portions 642b, 643b recessed toward the rear are formed in the central front portions of the left and right wall portions 642, 643. These rib fitting portions 642b, 643b extend upward from the front portions of the central cutouts 642a, 643a in the vertical direction, and the rib 603 fits into them when the tube holder 224 is properly attached to the holder attachment portion 640. Specifically, the left rib 603a fits into the left rib fitting portion 642a from the front, and the right rib 603b fits into the right rib fitting portion 643a from the front.

The right wall 643 is provided with a movable protrusion 651 having a sphere 651a biased to the left by a spring or the like, and the sphere 651a partially protrudes to the left from the left side surface of the right wall 643. Such movable protrusions 651 are provided in two locations: one between the two central and upper notches 643a and close to the upper notch 643a, and one between the two central and lower notches 643a and close to the lower notch 643a. Meanwhile, the tube holder 224 is provided with a recess 652 corresponding to the movable protrusion 651. The recesses 652 are provided in two locations: one between the two central and upper insertion holes 604 and close to the upper insertion hole 604, and one between the two central and lower insertion holes 604 and close to the lower insertion hole 604. In this embodiment, each recess 652 is formed as a through hole that penetrates the holder body 602 in the left-right direction (thickness direction).

The movable convex portion 651 and the concave portion 652 constitute the moderation mechanism 650. That is, when the tube holder 224 is fitted into the holder mounting portion 640, the movable convex portion 651 is first pressed to the right by the front side surface of the holder body 602, and the sphere 651a retracts. When the tube holder 224 is further fitted to the back and reaches a predetermined position (appropriate mounting position), the concave portion 652 of the holder body 602 faces the side of the movable convex portion 651. At this time, the sphere 651a of the movable convex portion 651 is biased toward the holder body 602 and protrudes, and fits into the concave portion 652. In this way, when the tube holder 224 is properly attached to the holder mounting portion 640, the movable convex portion 651 and the concave portion 652 engage with each other, and a sense of moderation is generated when the sphere 651a protrudes. The configuration of the detent mechanism 650 is not limited to the above, and other configurations may be used as long as they provide the operator with a sense of detent when attaching the tube holder 224.

The rib 603 of the tube holder 224 also serves as a pressure-receiving portion that receives pressure from the operator's fingers when the tube holder 224 is attached to the holder attachment portion 640. That is, the tube holder 224 is attached to the holder attachment portion 640 by, for example, grasping the left and right ends of the rib 603 with the thumb and middle finger, and pressing the front surface of the rib 603 backward with the tip of the index finger. However, the procedure for attaching the tube holder 224 to the holder attachment portion 640 is not limited to the above, and the tube holder 224 may be attached using other gripping methods.

As can be seen from the above description, the tube holder 224 can only be attached to the holder attachment part 640 in one position (first position), and cannot be attached in any other position (second position). Specifically, as shown in FIG. 9, the first position is when the rib 603 is located on the front side (nearby side) and is offset above the center position in the vertical direction, and in this position, the tube holder 224 is properly attached to the holder attachment part 640. In contrast, in a position reversed from the first position, the rib 603 abuts against the front ends of the left and right wall parts 642 and 643, and the holder body 602 does not fit into the groove 641. In addition, in a position reversed from the first position, the rib 603 does not fit into the rib fitting parts 642b and 643b, and the holder body 602 fits only halfway into the groove 641. Therefore, it is possible to prevent misidentification of the orientation of the tube holder 224.

(Embodiment 2)
Fig. 10 is a schematic diagram showing the overall configuration of a blood processing circuit including a liquid bag set and a pump tube set according to embodiment 2. As in embodiment 1, a blood processing circuit 1A used for HDF in RRT is shown as an example. This blood processing circuit 1A is generally the same as the blood processing circuit 1 in Fig. 1, but the connection mode of some lines is different from that of the blood processing circuit 1 in Fig. 1. This difference will be specifically described below. Note that the same reference numerals are used to designate components in the blood processing circuit 1A in Fig. 10 that correspond to those in the blood processing circuit 1 in Fig. 1.

In the blood treatment circuit 1A in FIG. 10, the connection between the dialysate line 213 and the recovery line 230 and the filter 102 of the three lines 213, 214, and 230 passing through the pump unit 202 is different from that of the blood treatment circuit 1 in FIG. 1. That is, when the dialysate line 213 goes downstream (to the right in FIG. 10) from the pump unit 202, it is connected to the dialysate heating line 301 extending from the upper part of the dialysate heater 303. The dialysate heating line 301 goes from the upper part to the lower part inside the dialysate heater 303, and further extends from the lower part of the dialysate heater 303 and is connected to the dialysate port 124 provided at the upper part of the filter 102. On the other hand, the recovery line 230 has its upstream end connected to the drainage port 25 provided at the lower part of the filter 102.

The blood processing circuit 1A described above can achieve the same effects as the blood processing circuit 1 according to embodiment 1.

The priming procedure when using this blood processing circuit 1A will be outlined with reference to Figures 10 and 11. Figure 11 is a schematic diagram showing the configuration when the filter in the circuit of Figure 10 is turned upside down (upside down). In priming, the blood pump 110 and pump unit 202 are driven to pass saline through each part, thereby performing washing and deairing, etc.

Specifically, priming of the blood processing circuit 1A includes the following steps (1) to (9). Note that the following mainly refers to the drive of the pumps 110 and 202 and the flow of physiological saline, and explanations of other operations are omitted, but clamp opening and closing operations and the like required to execute each step are performed as appropriate.
(1) In the state shown in FIG. 10, a bag 112 containing physiological saline is connected to a saline line 111 branching off from the blood removal line 101.
(2) The blood pump 110 is driven. As a result, physiological saline is passed through the saline line 111, the blood removal line 101, the arterial pressure chamber 115, the filter 102 (inside the filter 121 of the filter 102), and the blood return line 103 (passing through the mixing chamber 130 on the way).
(3) The filter 102 is turned upside down to the state shown in FIG.
(4) Physiological saline is again passed from the bag 112 through the circuit 1A, the blood pump 110 is driven, and the finger pump 222 to which the recovery line 230 is attached of the pump unit 202 is driven in the same forward direction as during treatment. This causes the physiological saline to pass through the saline line 111, the blood removal line 101, the arterial pressure chamber 115, the filter 102, the recovery line 230, and the waste line 232 in this order.
(5) Instead of the finger pump 222 to which the recovery line 230 is attached, the finger pump 222 to which the dialysate line 213 is attached is driven in the opposite direction to the operation during treatment. This causes the saline to pass through the saline line 111, the blood removal line 101, the arterial pressure chamber 115, the filter 102, the dialysate heating line 301, the dialysate line 213, and the first fluid bag 212 in this order.
(6) The blood pump 110 is stopped, and the storage bag 210 containing physiological saline is connected to the common line 211. Furthermore, the finger pump 222 to which the dialysis fluid line 213 is set is driven in the same forward direction as that during operation during treatment, and the finger pump 222 to which the recovery line 230 is set is also driven in the same forward direction as that during operation during treatment. As a result, physiological saline is passed through the common line 211, the dialysis fluid line 213, the dialysis fluid heating line 301, the filter 102, the recovery line 230, and the waste line 232 in this order.
(7) The bag 112 containing physiological saline is connected to the saline line 111, the blood pump 110 is driven, and the finger pump 222 to which the dialysis fluid line 213 is set is driven in the opposite direction to that during treatment. This causes the physiological saline to flow through the saline line 111, the blood removal line 101, the arterial pressure chamber 115, the filter 102, the dialysis fluid heating line 301, the dialysis fluid line 213, the common line 211, and the storage bag 210 in this order.
(8) Stop the pumps 110 and 222. The physiological saline in the storage bag 210 flows by its own weight through the common line 211 into the first liquid bag 212.
(9) The finger pump 222 to which the post-fluid replacement line 214 is set is driven in the same forward direction as during treatment. This causes the saline in the first fluid bag 212 to flow through the post-fluid replacement line 214, the post-fluid replacement heating line 302, the mixing chamber 130, and the blood return line 103 in this order.

The treatment fluid set 200 constituting this blood treatment circuit 1A is provided with markings to prevent erroneous connection when connecting to the blood treatment device 400 or other lines. In the treatment fluid set 200 in the expanded state shown in FIG. 12, each marking is shown as a triangular icon (similar to FIGS. 10 and 11). As shown, a marking 710 is provided near the connection of the dialysis fluid line 213 with the dialysis fluid heating line 301. This marking 710 is, for example, made of colored tape, and is, for example, green. A marking of the same color, green, is also provided near the connection of the dialysis fluid heating line 301 with the dialysis fluid line 213 (not shown).

Similarly, a marking 711 made of blue color tape is applied near the connection of the post-replacement line 214 with the post-replacement line 302. And a marking of the same color, blue, is also applied near the connection of the post-replacement line 302 with the post-replacement line 214 (not shown). Also, markings 712 and 713 made of yellow color tape are applied near the connection of the recovery line 230 with the drainage port 125 and near the connection of the pressure measurement line 703 with the blood processing device 400. And a marking of the same color, yellow, is also applied to the connection of the drainage port 125 and the pressure measurement line 703 in the blood processing device 400.

This makes it easy to understand the connection combinations when connecting each line of the treatment liquid set 200 to other lines, etc., and prevents incorrect connections from occurring.

In addition, because this processing liquid set 200 has multiple lines, if the lines become tangled when not in use, handling can be tedious. However, by bundling the lines together when not in use, handling is made easier.

That is, as shown in FIG. 13, in the unused treatment liquid set 200, multiple lines are bundled together by clips 720 to 723. Specifically, the bundle of waste lines 232 wound in a circular shape is held by the small clip 720, the bundle of common lines 211 wound in a circular shape is held by the small clip 721, and further, the bundle of waste lines 232 and the bundle of common lines 211 are held together by the large clip 722. Furthermore, the bundle of dialysis fluid lines 213 wound in a circular shape and the bundle of recovery lines 230 wound in a circular shape are held together by the large clip 723.

This prevents multiple lines from becoming tangled while an unused treatment liquid set 200 is stored in a storage bag, or when the treatment liquid set 200 is removed from a storage bag in preparation for treatment, thereby reducing the effort required during use.

The present invention can be suitably applied to the liquid bag set, pump tube set, and tube holder that constitute the blood processing circuit for RRT.

1, 1A Blood processing circuit 212 First liquid bag 224 Tube holder 231 Second liquid bag 240 Liquid bag (first liquid bag, second liquid bag)
244 Through hole 250, 260 First tube 251, 253, 261, 263 L-shaped joint 252, 262 Second tube 254, 264 Third tube 500 Liquid bag set 501 Bag unit 502 Bag holder 510 Panel 511 Support arm 530 Base end portion 531 Tip portion 532 Cutout portion 540a Space (cutout)
550 Upper supported part 551 Lower supported part 570, 571 Joint support part 600 Pump tube set 601 Tube 601a Pressured part 602 Holder body 603 Rib (pressure receiving part)
604 Insertion hole 651 Movable convex portion 652 Concave portion A Measuring portion B Non-measuring portion

Claims (7)

A liquid bag set for use in a blood treatment circuit to store a liquid flowing through the circuit, and for use in measuring a liquid weight measured by a weight sensor of a blood treatment device that controls blood treatment by the circuit, comprising:
a plurality of bags including a first bag for storing liquid and a second bag located above the first bag ;
a holder configured separately from the first bag and the second bag, integrally supporting the first bag and the second bag, and being attached to the blood processing device so as to be weighed by the weight sensor together with the first bag and the second bag;
a tube connected at one end to the bag for supplying liquid to the bag or discharging liquid from the bag;
The tube is
a supported portion supported by the blood processing device;
a measurement portion that is a portion closer to the one end than the supported portion and is measured by the weight sensor;
a non-weighing portion that is a portion on the other end side of the supported portion and is not weighed by the weight sensor ,
The tube connected to the second bag among the tubes has a lateral extension portion extending laterally between the first bag and the second bag .
Liquid bag set. The holder has a flat panel and a support arm extending from the panel,
The plurality of bags have through holes through which the support arms are inserted.
2. The fluid bag set of claim 1 . The first bag stores a dialysis fluid or a replacement fluid, the second bag stores a drainage fluid from a filter of the blood treatment circuit, and the first bag is located vertically below the second bag.
2. The fluid bag set of claim 1 . a lower tube extending from the first bag extends in one direction in the left-right direction, and an upper tube extending from the second bag extends in the other direction in the left-right direction;
2. The fluid bag set of claim 1 . the first bag has a lower tube connecting portion to which the lower tube is connected, the lower tube connecting portion being offset to the other side in the left-right direction with respect to the first bag,
the second bag has an upper tube connecting portion to which the upper tube is connected, and the upper tube connecting portion is located offset to one side in the left-right direction with respect to the second bag.
5. The fluid bag set according to claim 4 . the holder has a notch at a portion overlapping with the tube when viewed from the front in a state where the holder is attached to the blood processing device;
2. The fluid bag set of claim 1 . 2. The fluid bag set according to claim 1, wherein the holder is made of a material harder than the bag and is supported by the blood processing device in a state where the holder supports the bag and is integral with the bag.

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