JP5283425B2 - Extracorporeal circuit - Google Patents

Extracorporeal circuit Download PDF

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JP5283425B2
JP5283425B2 JP2008127800A JP2008127800A JP5283425B2 JP 5283425 B2 JP5283425 B2 JP 5283425B2 JP 2008127800 A JP2008127800 A JP 2008127800A JP 2008127800 A JP2008127800 A JP 2008127800A JP 5283425 B2 JP5283425 B2 JP 5283425B2
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blood
circuit
bag
dialysate
binding band
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JP2009273662A (en
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章 宮下
賢悟 小林
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Asahi Kasei Medical Co Ltd
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本発明は、白血球除去、血液吸着、血液透析、血液濾過、血液濾過透析等の血液の体外循環を行う血液浄化装置に使用される体外循環回路に関する。   The present invention relates to an extracorporeal circuit used in a blood purification apparatus that performs extracorporeal blood circulation such as leukocyte removal, blood adsorption, hemodialysis, blood filtration, and hemofiltration dialysis.

血液透析時に用いられる血液系回路は一般的には軟質チューブを使用し、例えば特許文献1の図9に開示されている。血液系回路は採血回路と返血回路に分かれており、採血回路はプライミング、補液または血液回収を行うための生食ライン、血液ポンプチューブ、動脈側ドリップチャンバを有し、返血回路は静脈側ドリップチャンバを有する構成となっている。また、血液系回路の他に、ダイアライザの透析液入口に接続される透析液回路とダイアライザの透析液出口に接続される濾過液回路の液系回路も必要である。   A blood system circuit used at the time of hemodialysis generally uses a soft tube, and is disclosed in, for example, FIG. The blood system circuit is divided into a blood collection circuit and a blood return circuit. The blood collection circuit has a phagocytic line for priming, replenishment or blood collection, a blood pump tube, an arterial drip chamber, and the blood return circuit is a venous drip. It has a configuration having a chamber. In addition to the blood circuit, a dialysate circuit connected to the dialysate inlet of the dialyzer and a filtrate circuit connected to the dialysate outlet of the dialyzer are also required.

このように、従来、血液浄化で使用されてきた体外循環回路は独立したいくつかの回路からなるため、体外循環回路を血液浄化器に接続して血液浄化装置に装着する際には、接続方法あるいは装着方法が分かり難く、更に軟質チューブ等が絡みあう等の欠点があった。   Thus, since the extracorporeal circuit conventionally used in blood purification consists of several independent circuits, when connecting the extracorporeal circuit to the blood purifier and attaching it to the blood purification device, the connection method Alternatively, the mounting method is difficult to understand, and there are further disadvantages such as soft tubes and the like being entangled.

このような問題点を解決するために、特許文献2では採血回路と返血回路をドリップチャンバ部分で一体化し、全体をコンパクト化して、使用時に個々のドリップチャンバを設置する手間や軟質チューブ等が絡まる等の煩わしさを解消した。しかし、血液系回路は一体化されたものの、依然として、血液系回路のどの部分を血液浄化装置のどこに接続するかという点は分かり難く、また液系回路の問題点は未解決であった。   In order to solve such a problem, in Patent Document 2, the blood collection circuit and the blood return circuit are integrated in the drip chamber portion, the whole is made compact, and the trouble of installing each drip chamber at the time of use, a soft tube, etc. Eliminates the hassle of tangling. However, although the blood system circuit is integrated, it is still difficult to understand which part of the blood system circuit is connected to the blood purification apparatus, and the problem of the liquid system circuit has not been solved.

特開2006−340845号公報JP 2006-340845 A 特許第3145852号公報Japanese Patent No. 3145852

本発明の課題は、上記従来技術の問題点に鑑み、血液浄化装置に簡便かつ確実に装着できる軟質チューブからなる体外循環回路を提供することにある。   An object of the present invention is to provide an extracorporeal circuit comprising a soft tube that can be easily and reliably attached to a blood purification apparatus in view of the above-described problems of the prior art.

本発明者等は、体外循環回路を血液系回路と液系回路の2つの部分に分けて、それぞれの軟質チューブからなる回路を、回路の端部と結束バンドによって各パネルに固定し、各パネルに血液浄化装置への固定部を設けた。そして、各回路の位置と長さを調節することによって、各パネルを血液浄化装置の所定の位置に装着して結束バンドを解けば、体外循環回路と血液浄化装置との装着位置関係が容易に把握できるように構成できることを見出し、本発明を完成するに至った。   The inventors divide the extracorporeal circuit into two parts, a blood system circuit and a liquid system circuit, and fix the circuit composed of each soft tube to each panel by the end of the circuit and a binding band. A fixing part to the blood purification apparatus was provided. Then, by adjusting the position and length of each circuit, if each panel is attached to a predetermined position of the blood purification device and the binding band is released, the attachment positional relationship between the extracorporeal circuit and the blood purification device can be easily achieved. The present inventors have found that it can be configured so as to be grasped, and have completed the present invention.

即ち、本発明に係る体外循環回路の第1の構成は、軟質チューブからなる血液系回路を含む血液浄化装置用の体外循環回路であって、前記血液系回路は第一の結束バンドによって束ねられて血液系パネルに脱着可能に保持され、前記血液系パネルは前記血液浄化装置の上部に設けられた第一のハンガー部に固定するための第一の固定部位を有し、前記血液系回路は、前記血液系パネルを前記第一の固定部位を介して前記血液浄化装置の上部に設けられた前記第一のハンガー部に固定し、前記第一の結束バンドを解くと、前記血液系回路上の各装着部分がその自重により垂下された状態で前記血液浄化装置上の対応部位付近に配置されるように構成されていることを特徴とする。 That is, a first configuration of the extracorporeal circuit according to the present invention is an extracorporeal circuit for a blood purification apparatus including a blood system circuit made of a soft tube, and the blood system circuit is bundled by a first binding band. The blood system panel has a first fixing part for fixing to a first hanger part provided at the upper part of the blood purification device, and the blood system circuit is When the blood system panel is fixed to the first hanger part provided on the upper part of the blood purification device through the first fixing part and the first binding band is released , the blood system circuit is Each mounting part is arranged in the vicinity of a corresponding part on the blood purification apparatus in a state where it is suspended by its own weight.

また、本発明に係る体外循環回路の第の構成は、前記第の構成において、前記血液系回路は、患者から採血された血液を血液浄化器に送る採血回路部と、前記血液浄化器の血液を患者に戻す返血回路部と、前記採血回路部と前記返血回路部とを接続する接続部材とからなり、前記採血回路部は、一端側が患者に接続するための端部であり、他端側が前記血液浄化器の血液入口に接続するための端部である採血回路部上に、プライミング用の分岐流路と、ピロー部と、血液ポンプチューブと、抗凝固剤導入用の分岐流路と、第一の圧力測定ラインが連結された動脈側ドリップチャンバが配置され、前記プライミング用の分岐流路の端部は前記血液系パネルに脱着可能に固定され、前記第一の圧力測定ラインは、端部が前記血液系パネルに固定された第一の位置決め部材に接続され、前記返血回路部は、一端側が前記血液浄化器の血液出口に接続するための端部であり、他端側が患者に接続するための端部である返血回路部上に、補液導入用の分岐流路と、第二の圧力測定ラインが連結された静脈側ドリップチャンバが配置され、前記第二の圧力測定ラインは、端部が前記血液系パネルに固定された第二の位置決め部材に接続され、前記接続部材は、前記採血回路部の前記血液浄化器の血液入口に接続するための端部と、前記返血回路部の前記血液浄化器の血液出口に接続するための端部とを接続し、前記第一の結束バンドは、前記採血回路部を束ねる採血回路部結束バンドと、前記返血回路部を束ねる返血回路部結束バンドとを含み、前記血液系回路は、前記採血回路部結束バンドと前記返血回路部結束バンドとを解くと、前記採血回路部上の前記ピロー部は前記血液浄化装置の採血陰圧検知器付近に配置され、前記血液ポンプチューブは血液ポンプ付近に配置され、前記動脈側ドリップチャンバは動脈側ドリップチャンバ固定部位付近に配置され、前記静脈側ドリップチャンバは静脈側ドリップチャンバ固定部位付近に配置されることを特徴とする。 According to a second configuration of the extracorporeal circuit according to the present invention, in the first configuration, the blood system circuit includes a blood collection circuit section that sends blood collected from a patient to the blood purification device, and the blood purification device. A blood return circuit part for returning the blood to the patient, and a connection member for connecting the blood collection circuit part and the blood return circuit part, and the blood collection circuit part is an end part for connecting one end side to the patient The other end side is an end portion for connecting to the blood inlet of the blood purifier, on the blood collection circuit portion, a branch channel for priming, a pillow portion, a blood pump tube, and a branch for introducing an anticoagulant An arterial drip chamber connected to the flow path and the first pressure measurement line is disposed, and an end of the priming branch flow path is detachably fixed to the blood system panel, and the first pressure measurement The end of the line is fixed to the blood system panel. The blood return circuit portion is connected to the first positioning member, and one end side is an end portion for connecting to the blood outlet of the blood purifier, and the other end side is an end portion for connecting to the patient. On the blood return circuit portion, a branch channel for introducing a replacement fluid and a venous drip chamber connected to a second pressure measurement line are arranged, and the end of the second pressure measurement line is the blood system panel. Connected to a second positioning member fixed to the end of the blood collection circuit portion for connection to the blood inlet of the blood purification device, and the blood purification device of the blood return circuit portion. An end for connecting to the blood outlet is connected, and the first binding band includes a blood collection circuit unit binding band for binding the blood collection circuit unit and a blood return circuit unit binding band for binding the blood return circuit unit. The blood system circuit includes the blood collection circuit unit binding van And the blood return circuit unit binding band, the pillow part on the blood collection circuit unit is disposed in the vicinity of the blood collection negative pressure detector of the blood purification device, the blood pump tube is disposed in the vicinity of the blood pump, The arterial drip chamber is disposed in the vicinity of the arterial drip chamber fixing site, and the venous drip chamber is disposed in the vicinity of the venous drip chamber fixing site.

また、本発明に係る体外循環回路の第の構成は、前記第1、第2の構成において、前記血液浄化装置用の体外循環回路は更に軟質チューブからなる液系回路が連結された軟質バッグを含み、該液系回路及び軟質バッグは第二の結束バンドによって束ねられて液系パネルに脱着可能に保持され、前記液系パネルは前記血液浄化装置の上部に設けられた第二のハンガー部に固定するための第二の固定部位を有し、前記液系回路が連結された軟質バッグは、前記液系パネルを前記第二の固定部位を介して前記血液浄化装置の上部に設けられた前記第二のハンガー部に固定して前記第二の結束バンドを解き、前記軟質バッグをそのまま平行移動すれば前記血液浄化装置の所定の位置に設置できるように構成されていることを特徴とする。 According to a third configuration of the extracorporeal circuit according to the present invention, in the first and second configurations, the extracorporeal circuit for the blood purification apparatus is a soft bag in which a liquid circuit composed of a soft tube is further connected. The liquid system circuit and the soft bag are bundled by a second binding band and are detachably held on the liquid system panel, and the liquid system panel is a second hanger part provided on the upper part of the blood purification device. A soft bag having a second fixing part for fixing to the liquid crystal circuit and connected to the liquid circuit is provided on the blood purification device via the second fixing part. Fixed to the second hanger part, the second binding band is unwound, and the flexible bag can be installed in a predetermined position of the blood purification device by translating the soft bag as it is. .

また、本発明に係る体外循環回路の第の構成は、前記第の構成において、前記軟質チューブからなる液系回路が連結された軟質バッグとして濾過液回路部が連結された濾過液量計測バッグを有し、前記濾過液回路部は、一端側が排液するための端部であり、他端側が前記濾過液量計測バッグに接続された前記濾過液回路部上に、血液浄化器の透析液出口に連結する分岐流路を有し、該分岐流路には第三の圧力測定ラインと濾過液ポンプチューブが設けられており、前記第二の結束バンドは、前記濾過液回路部と前記濾過液量計測バッグとを束ねる濾過液系結束バンドを含むことを特徴とする。 The fourth configuration of the extracorporeal circuit according to the present invention is the measurement of the amount of filtrate in which the filtrate circuit unit is connected as a soft bag to which the liquid system circuit composed of the soft tube is connected in the third configuration. A dialysis of a blood purifier on the filtrate circuit portion connected to the filtrate amount measurement bag, the other end side being an end portion for draining one end side. A branch flow path connected to the liquid outlet, the branch flow path is provided with a third pressure measurement line and a filtrate pump tube, and the second binding band includes the filtrate circuit section and the filtrate It is characterized by including a filtrate-type binding band for bundling the filtrate amount measurement bag.

また、本発明に係る体外循環回路の第の構成は、前記第の構成において、前記軟質チューブからなる液系回路が連結された軟質バッグとして透析液回路部が連結された透析液量計測バッグを有し、前記透析液回路部は、一端側が透析液バッグに接続するための端部であり、他端側が前記透析液量計測バッグに接続された前記透析液回路部上に、血液浄化器の透析液入口に連結する分岐流路を有し、該分岐流路には透析液ポンプチューブが設けられており、前記第二の結束バンドは、前記透析液回路部と前記透析液量計測バッグとを束ねる透析液系結束バンドを含むことを特徴とする。 The fifth configuration of the extracorporeal circuit according to the present invention is the same as the fourth configuration, except that the dialysate circuit unit is connected as a soft bag to which the liquid circuit composed of the soft tube is connected. The dialysate circuit part has a bag, and one end side is an end part for connection to the dialysate bag, and the other end side is on the dialysate circuit part connected to the dialysate amount measurement bag. A dialysis fluid pump tube is provided in the branch passage, and the second binding band includes the dialysis fluid circuit section and the dialysis fluid volume measurement. A dialysate system binding band for binding the bag is included.

また、本発明に係る体外循環回路の第の構成は、前記第、第の構成において、前記軟質チューブからなる液系回路が連結された軟質バッグとして補液回路部が連結された補液量計測バッグを有し、前記補液回路部は、一端側が補液バッグに接続するための端部であり、他端側が前記補液量計測バッグに接続された前記補液回路部上に、血液浄化器の血液を患者に戻す返血回路部の補液導入用の分岐流路に連結するための分岐流路を有し、該分岐流路には補液ポンプチューブが設けられており、前記第二の結束バンドは、前記補液回路部と前記補液量計測バッグとを束ねる補液系結束バンドを含むことを特徴とする。 A sixth configuration of the extracorporeal circuit according to the present invention is the replacement fluid amount in which the replacement fluid circuit portion is connected as a soft bag in which the fluid circuit composed of the soft tube is connected in the fourth and fifth configurations. A blood bag of the blood purifier on the replacement fluid circuit portion, one end of which is connected to the replacement fluid bag, and the other end is connected to the replacement fluid volume measurement bag. A branch flow path for connecting to a branch flow path for replacement fluid introduction of the blood return circuit unit for returning the blood to the patient, and the branch flow path is provided with a replacement fluid pump tube, and the second binding band is And a replacement fluid system binding band that bundles the replacement fluid circuit section and the replacement fluid amount measurement bag.

また、本発明に係る体外循環回路の第の構成は、前記第の構成において、前記透析液バッグに接続するための端部が前記液系パネルに脱着可能に固定されたことを特徴とする。 The seventh configuration of the extracorporeal circuit according to the present invention is characterized in that, in the fifth configuration, an end for connecting to the dialysate bag is detachably fixed to the liquid system panel. To do.

また、本発明に係る体外循環回路の第の構成は、前記第の構成において、前記補液バッグに接続するための端部が前記液系パネルに脱着可能に固定されたことを特徴とする。 Further, an eighth configuration of the extracorporeal circuit according to the present invention is characterized in that, in the sixth configuration, an end portion for connection to the replacement fluid bag is detachably fixed to the liquid system panel. .

本発明に係る体外循環回路の第1の構成によれば、血液系パネルを第一の固定部位を介して血液浄化装置の上部に設けられた第一のハンガー部に固定すると、血液系回路上の各装着部分がその自重により垂下された状態で血液浄化装置上の対応部位付近に配置されるため血液系回路の各部位の血液浄化装置への装着が簡便にでき、しかも装着を誤る恐れがない。   According to the first configuration of the extracorporeal circuit according to the present invention, when the blood system panel is fixed to the first hanger portion provided on the upper part of the blood purification device via the first fixing portion, Since each of the mounting parts is suspended by its own weight in the vicinity of the corresponding part on the blood purification device, it is possible to easily attach each part of the blood system circuit to the blood purification device, and there is a risk of erroneous mounting. Absent.

また、血液系パネルを第一の固定部位を介して血液浄化装置の上部に設けられた第一のハンガー部に固定して第一の結束バンドを解くと、血液系回路上の各装着部分がその自重により垂下された状態で血液浄化装置上の対応部位付近に配置されるため血液系回路の各部位の血液浄化装置への装着が簡便にでき、しかも装着を誤る恐れがない。また、第一の結束バンドによって血液系回路が束ねられているので、体外循環回路全体がコンパクトで取扱いが容易である。 In addition , when the blood system panel is fixed to the first hanger part provided on the upper part of the blood purification device via the first fixing part and the first binding band is released, each mounting part on the blood system circuit is Since it is placed in the vicinity of the corresponding site on the blood purification device while being suspended by its own weight, it is possible to easily attach each part of the blood system circuit to the blood purification device, and there is no risk of erroneous installation. Further, since the blood system circuit is bundled by the first binding band, the entire extracorporeal circuit is compact and easy to handle.

本発明に係る体外循環回路の第の構成によれば、血液系パネルを第一の固定部位を介して血液浄化装置の上部に設けられた第一のハンガー部に固定して採血回路部結束バンド及び返血回路部結束バンドを解くと、採血回路部上のピロー部は血液浄化装置の採血陰圧検知器付近に配置され、血液ポンプチューブは血液ポンプ付近に配置され、動脈側ドリップチャンバは動脈側ドリップチャンバ固定部位付近に配置され、静脈側ドリップチャンバは静脈側ドリップチャンバ固定部位付近に配置されるので、血液浄化装置への装着が簡便にでき、しかも装着を誤る恐れがない。 According to the second configuration of the extracorporeal circuit according to the present invention, the blood system panel is fixed to the first hanger part provided on the upper part of the blood purification device via the first fixing part, and the blood collecting circuit part is bound. When the band and the blood return circuit unit binding band are released, the pillow part on the blood collection circuit unit is arranged near the blood collection negative pressure detector of the blood purification device, the blood pump tube is arranged near the blood pump, and the arterial drip chamber is Since it is arranged in the vicinity of the artery-side drip chamber fixing portion and the vein-side drip chamber is arranged in the vicinity of the vein-side drip chamber fixing portion, it can be easily attached to the blood purification apparatus, and there is no risk of erroneous attachment.

本発明に係る体外循環回路の第の構成によれば、液系パネルを第二の固定部位を介して血液浄化装置の上部に設けられた第二のハンガー部に固定して第二の結束バンドを解き、軟質バッグをそのまま平行移動すれば血液浄化装置の所定の位置に設置できるため液系回路が連結された軟質バッグの血液浄化装置への装着が簡便にでき、しかも装着を誤る恐れがない。 According to the third configuration of the extracorporeal circuit according to the present invention, the liquid system panel is fixed to the second hanger portion provided on the upper part of the blood purification apparatus via the second fixing portion, and the second binding is performed. If the band is released and the soft bag is translated as it is, it can be installed at a predetermined position in the blood purification device, so that the soft bag connected with the liquid system circuit can be easily attached to the blood purification device, and there is a risk of erroneous attachment. Absent.

本発明に係る体外循環回路の第の構成によれば、液系パネルを第二の固定部位を介して血液浄化装置の上部に設けられた第二のハンガー部に固定して濾過液系結束バンドを解き、濾過液量計測バッグをそのまま平行移動すれば血液浄化装置の所定の位置に設置できるため濾過液回路部が連結された濾過液量計測バッグの血液浄化装置への装着が簡便にでき、しかも装着を誤る恐れがない。 According to the fourth configuration of the extracorporeal circuit according to the present invention, the liquid system panel is fixed to the second hanger portion provided on the upper part of the blood purification device via the second fixing portion, and the filtrate system is bound. If the band is opened and the filtrate measuring bag is moved in parallel, it can be installed at a predetermined position on the blood purification device, so that the filtrate measuring bag connected to the filtrate circuit can be easily attached to the blood purification device. And there is no fear of wearing it wrong.

本発明に係る体外循環回路の第の構成によれば、液系パネルを第二の固定部位を介して血液浄化装置の上部に設けられた第二のハンガー部に固定して透析液系結束バンドを解き、透析液量計測バッグをそのまま平行移動すれば血液浄化装置の所定の位置に設置できるため透析液回路部が連結された透析液量計測バッグの血液浄化装置への装着が簡便にでき、しかも装着を誤る恐れがない。 According to the fifth configuration of the extracorporeal circuit according to the present invention, the liquid system panel is fixed to the second hanger portion provided on the upper part of the blood purification apparatus via the second fixing portion, and the dialysate system binding is performed. If the band is released and the dialysate volume measuring bag is translated as it is, it can be installed at a predetermined position on the blood purifier, so the dialysate volume measuring bag connected to the dialysate circuit section can be easily attached to the blood purifier. And there is no fear of wearing it wrong.

本発明に係る体外循環回路の第の構成によれば、液系パネルを第二の固定部位を介して血液浄化装置の上部に設けられた第二のハンガー部に固定して補液系結束バンドを解き、補液量計測バッグをそのまま平行移動すれば血液浄化装置の所定の位置に設置できるため補液回路部が連結された補液量計測バッグの血液浄化装置への装着が簡便にでき、しかも装着を誤る恐れがない。 According to the sixth configuration of the extracorporeal circuit according to the present invention, the liquid system panel is fixed to the second hanger portion provided on the upper part of the blood purification apparatus via the second fixing portion, and the replacement fluid system binding band is fixed. If the solution volume measuring bag is translated as it is, it can be installed at a predetermined position of the blood purification device, so the replacement fluid volume measuring bag connected to the fluid replacement circuit section can be easily attached to the blood purification device. There is no fear of mistakes.

本発明に係る体外循環回路の第、第の構成によれば、透析液バッグに接続するための端部、或いは補液バッグに接続するための端部がそれぞれ液系パネルに脱着可能に固定されたことで、透析液バッグに接続するための端部を該透析液バッグに接続する前段階、或いは補液バッグに接続するための端部を該補液バッグに接続する前段階ではそれぞれ液系パネルに固定しておくことで床面等に接触して汚染されることがなく、無菌状態を維持することが出来る。 According to the seventh and eighth configurations of the extracorporeal circuit according to the present invention, the end for connecting to the dialysate bag or the end for connecting to the replacement fluid bag is detachably fixed to the liquid system panel. As a result, each of the liquid system panels in the stage before connecting the end portion for connecting to the dialysate bag to the dialysate bag, or in the stage before connecting the end portion for connecting to the replacement fluid bag to the replacement fluid bag, respectively. By fixing it to the floor, it is not contaminated by contact with the floor surface or the like, and the aseptic state can be maintained.

即ち、本発明に係る体外循環回路は、血液系回路と液系回路の2つの部分に纏められているので取扱いが容易である。血液系パネルを血液浄化装置の上部に設けられた第一のハンガー部に固定して第一の結束バンドを解けば、血液系回路の各装着部が血液浄化装置の各装着部に位置決めされ、或いは液系パネルを血液浄化装置に装着して第二の結束バンドを解けば、濾過液量計測バッグ、透析液量計測バッグおよび補液量計測バッグをそのまま平行移動して簡単に血液浄化装置に装着することができ、更に透析液量計測バッグおよび補液量計測バッグに接続する接続端部は液系パネルに固定されているので、該接続端部を誤って不潔にする恐れがない。以上から、本発明の体外循環回路を用いれば、簡便、確実、且つ安全に血液浄化装置に体外循環回路を装着することができる。   That is, the extracorporeal circuit according to the present invention is easy to handle because it is integrated into two parts, a blood system circuit and a liquid system circuit. If the blood system panel is fixed to the first hanger part provided on the upper part of the blood purification device and the first binding band is released, each mounting part of the blood system circuit is positioned at each mounting part of the blood purification device, Alternatively, when the liquid system panel is attached to the blood purification device and the second binding band is released, the filtrate volume measurement bag, dialysate volume measurement bag, and replacement fluid volume measurement bag are simply translated and attached to the blood purification device. In addition, since the connection end connected to the dialysate measurement bag and the replacement fluid measurement bag is fixed to the liquid system panel, there is no fear that the connection end is accidentally tainted. From the above, if the extracorporeal circuit of the present invention is used, the extracorporeal circuit can be attached to the blood purification device simply, reliably and safely.

以下、図面を参照して、本発明の好ましい実施の形態について説明する。本実施の形態では、例えば持続的血液濾過法(CHF)と持続的血液透析法(CHD)とを複合させた持続的血液濾過透析法(CHDF)を実施する体外循環回路1について説明する。   Hereinafter, preferred embodiments of the present invention will be described with reference to the drawings. In the present embodiment, for example, an extracorporeal circuit 1 that performs continuous hemofiltration dialysis (CHDF) in which continuous hemofiltration (CHF) and continuous hemodialysis (CHD) are combined will be described.

図1(a)は本発明の実施形態に係る血液系回路が血液系パネルに保持されて収納された状態を示す模式図、図1(b)は本発明の実施形態に係る血液系回路の一部が血液系パネルに支持された状態で自重により垂下した様子を示す図、図2(a)は本発明の実施形態に係る液系回路が液系パネルに保持されて収納された状態を示す模式図、図2(b)は結束バンドを解いて液系回路に連結された各軟質バッグを取り外した様子を示す図、図3は本発明の実施形態に係る体外循環回路が装着される血液浄化装置の外観図、図4は血液系パネルが血液浄化装置の上部に設けられた第一のハンガー部に固定され、結束バンドを解いて血液系回路の一部が該血液系パネルに支持された状態で自重により垂下されて該血液系回路の各装着部が血液浄化装置の装着部位に位置決めされた様子を示す図、図5は液系パネルが血液浄化装置の上部に設けられた第二のハンガー部に固定され、結束バンドを解いて液系回路に連結された各軟質バッグを血液浄化装置に装着した様子を示す図である。   FIG. 1A is a schematic diagram showing a state in which a blood system circuit according to an embodiment of the present invention is held and housed in a blood system panel, and FIG. 1B is a diagram of the blood system circuit according to an embodiment of the present invention. FIG. 2A shows a state in which a part of the blood system is suspended by its own weight while being supported by the blood system panel, and FIG. 2A shows a state in which the liquid system circuit according to the embodiment of the present invention is held and stored in the liquid system panel. FIG. 2B is a diagram showing a state in which each soft bag connected to the liquid circuit is removed by unbundling the binding band, and FIG. 3 is attached with the extracorporeal circuit according to the embodiment of the present invention. FIG. 4 shows an external view of the blood purification apparatus. FIG. 4 shows a blood system panel fixed to a first hanger portion provided at the upper part of the blood purification apparatus, and a part of the blood system circuit is supported by the blood system panel by unwinding the binding band. In this state, it is suspended by its own weight, and each attachment part of the blood system circuit is blood purified. FIG. 5 shows a state in which the liquid system panel is fixed to the second hanger part provided on the upper part of the blood purification apparatus, and the binding band is released to connect to the liquid system circuit. It is a figure which shows a mode that each soft bag was mounted | worn with the blood purification apparatus.

本発明に係る血液浄化装置4用の体外循環回路1は、図1に示す血液系回路2と、図3に示す液系回路3の2つの部分からなる。なお、白血球除去や血液吸着のような血液浄化療法を行う場合には液系回路3は無くても良い。   The extracorporeal circuit 1 for the blood purification apparatus 4 according to the present invention comprises two parts, a blood system circuit 2 shown in FIG. 1 and a liquid system circuit 3 shown in FIG. In the case of performing blood purification therapy such as leukocyte removal or blood adsorption, the liquid circuit 3 may be omitted.

図1(a)において、主に軟質チューブからなる血液系回路2は第一の結束バンド81,82によって束ねられて血液系パネル70に脱着可能に保持される。血液系回路2は更に採血回路部11と、血液浄化器6の血液を患者に戻す返血回路部12と、採血回路部11と返血回路部12を繋ぐ接続部材となるダミーチューブ51とからなる。ダミーチューブ51は、採血回路部11の血液浄化器6の血液入口6aに接続するための端部17と、返血回路部12の血液浄化器6の血液出口6bに接続するための端部18とを接続する。また、接続部材となるダミーチューブ51は血液系回路2の採血回路部11と返血回路部12との左右方向の位置決め部材を兼ねる。   In FIG. 1A, blood system circuit 2 mainly composed of a soft tube is bundled by first binding bands 81 and 82 and is detachably held on blood system panel 70. The blood system circuit 2 further includes a blood collection circuit unit 11, a blood return circuit unit 12 that returns the blood of the blood purifier 6 to the patient, and a dummy tube 51 that serves as a connection member that connects the blood collection circuit unit 11 and the blood return circuit unit 12. Become. The dummy tube 51 has an end 17 for connecting to the blood inlet 6a of the blood purifier 6 of the blood collection circuit unit 11 and an end 18 for connecting to the blood outlet 6b of the blood purifier 6 of the blood return circuit unit 12. And connect. The dummy tube 51 serving as a connection member also serves as a positioning member in the left-right direction for the blood collection circuit unit 11 and the blood return circuit unit 12 of the blood system circuit 2.

血液系パネル70の形状、材質は、図3に示す血液浄化装置4の上部に設けられた第一のハンガー部となる突起部分5aに固定できて血液系回路2を固定できるものであれば、どのような形状、材質であっても良いが、平板状で適度の剛性と可撓性を有するポリプロピレン等の硬質プラスチックが好ましい。血液系パネル70の第一の固定部位90は、血液浄化装置4の上部に設けられた第一のハンガー部となる突起部分5aに固定できる構造であればどのようなものであっても良いが、血液浄化装置4の上部に設けられた第一のハンガー部となる突起部分5aに嵌め込んで固定できる穴が、構造が簡単であり実用的なので好ましい。血液系パネル70を固定する血液浄化装置4上の部位は、定位置でなければならない。尚、図1及び図4中の71は血液系パネル70を取り扱うためのハンドル穴である。   As long as the shape and material of the blood system panel 70 can be fixed to the protruding portion 5a serving as the first hanger portion provided on the upper part of the blood purification apparatus 4 shown in FIG. Any shape and material may be used, but a hard plastic such as polypropylene having a flat plate shape and appropriate rigidity and flexibility is preferable. The first fixing portion 90 of the blood system panel 70 may be of any structure as long as it can be fixed to the protruding portion 5a serving as the first hanger portion provided on the upper portion of the blood purification device 4. A hole that can be fitted into and fixed to the protruding portion 5a that is the first hanger portion provided at the upper portion of the blood purification device 4 is preferable because the structure is simple and practical. The part on the blood purification apparatus 4 which fixes the blood system panel 70 must be a fixed position. In FIG. 1 and FIG. 4, reference numeral 71 denotes a handle hole for handling the blood system panel 70.

血液系回路2は第一の結束バンド81,82によって束ねられて血液系パネル70に脱着可能に固定される。第一の結束バンドの本数に制限はないが、主に採血回路部11を束ねる結束バンド81と、主に返血回路部12を束ねる結束バンド82に分けるのが好ましい。   Blood system circuit 2 is bundled by first binding bands 81 and 82 and fixed to blood system panel 70 so as to be removable. Although the number of the first binding bands is not limited, it is preferable to divide them into a binding band 81 that mainly bundles the blood collection circuit unit 11 and a binding band 82 that mainly bundles the blood return circuit unit 12.

採血回路部11の一端は患者に接続するための端部13であり、該端部13は図示しない採血針等に接続される。採血回路部11の他端は血液浄化器6の血液入口6aに接続するための端部17である。   One end of the blood collection circuit unit 11 is an end 13 for connecting to a patient, and the end 13 is connected to a blood collection needle (not shown) or the like. The other end of the blood collection circuit portion 11 is an end portion 17 for connection to the blood inlet 6a of the blood purifier 6.

採血回路部11上には、使用前に各回路に液を充満させるためのプライミング用の分岐流路21と、ピロー部14と、血液ポンプチューブ15と、抗凝固剤導入用の分岐流路22と、第一の圧力測定ライン23が連結された動脈側ドリップチャンバ16が配置されている。プライミング用の分岐流路21と、ピロー部14と、血液ポンプチューブ15と、抗凝固剤導入用の分岐流路22と、動脈側ドリップチャンバ16の配置の順序は、プライミング用の分岐流路21が患者に接続するための端部13に最も近ければどのような順序であっても良いが、図3に示す本実施形態の血液浄化装置4の配置構成では、患者に接続するための端部13から順に、プライミング用の分岐流路21、ピロー部14、血液ポンプチューブ15、抗凝固剤導入用の分岐流路22、動脈側ドリップチャンバ16、血液浄化器6の血液入口6aに接続するための端部17の順序で配置されていることが好ましい。   On the blood collection circuit unit 11, a priming branch channel 21, a pillow unit 14, a blood pump tube 15, and a branch channel 22 for introducing an anticoagulant are provided to fill each circuit with liquid before use. The arterial drip chamber 16 to which the first pressure measurement line 23 is connected is disposed. The order of arrangement of the branch channel 21 for priming, the pillow part 14, the blood pump tube 15, the branch channel 22 for introducing an anticoagulant, and the arterial drip chamber 16 is as follows. Can be arranged in any order as long as it is closest to the end 13 for connecting to the patient, but in the arrangement of the blood purification apparatus 4 of this embodiment shown in FIG. 3, the end for connecting to the patient In order from 13, to connect to the branch channel 21 for priming, the pillow part 14, the blood pump tube 15, the branch channel 22 for introducing the anticoagulant, the arterial drip chamber 16, and the blood inlet 6 a of the blood purifier 6. It is preferable that the end portions 17 are arranged in this order.

返血回路部12の一端は血液浄化器6の血液出口6bに接続するための端部18である。返血回路部12の他端は患者に接続するための端部20であり、該端部20は図示しない返血針等に接続される。   One end of the blood return circuit portion 12 is an end portion 18 for connection to the blood outlet 6b of the blood purifier 6. The other end of the blood return circuit unit 12 is an end 20 for connection to a patient, and the end 20 is connected to a blood return needle or the like (not shown).

返血回路部12上には、図5に示す補液回路部102の分岐流路107の端部107aに、図1(b)に示す端部24aが接続される補液導入用の分岐流路24と、第二の圧力測定ライン25が連結された静脈側ドリップチャンバ19が配置されている。補液導入用の分岐流路24と、静脈側ドリップチャンバ19の配置の順序はどのような順序であっても良いが、図3に示す本実施形態の血液浄化装置4の配置構成では、血液浄化器6の血液出口6bに接続するための端部18から順に、補液導入用の分岐流路24、静脈側ドリップチャンバ19、患者に接続するための端部20の順序で配置されていることが好ましい。   On the blood return circuit section 12, the branch flow path 24 for introducing a replacement fluid is connected to the end section 107a of the branch path 107 of the replacement fluid circuit section 102 shown in FIG. And a venous drip chamber 19 to which the second pressure measurement line 25 is connected. The order of arrangement of the branch flow path 24 for introducing the replacement fluid and the venous drip chamber 19 may be any order. However, in the arrangement of the blood purification apparatus 4 of this embodiment shown in FIG. In order from the end 18 for connecting to the blood outlet 6b of the vessel 6, the branch flow channel 24 for introducing replacement fluid, the venous drip chamber 19, and the end 20 for connecting to the patient are arranged in this order. preferable.

プライミング用の分岐流路21の端部21aは血液系パネル70に設けられた係止片70aにより脱着可能に固定されており、第一の圧力測定ライン23はその端部23aが第一の位置決め部材となるダミーチューブ52の端部52aに第一の保護フィルタ26を介在させて接続され、ダミーチューブ52の他端部52bが血液系パネル70に設けられた係止片70bにより脱着可能に固定されている。   The end portion 21a of the priming branch channel 21 is detachably fixed by a locking piece 70a provided in the blood system panel 70, and the end portion 23a of the first pressure measurement line 23 is positioned in the first position. The first protective filter 26 is interposed between the end portion 52a of the dummy tube 52 serving as a member, and the other end portion 52b of the dummy tube 52 is detachably fixed by a locking piece 70b provided on the blood system panel 70. Has been.

また、第二の圧力測定ライン25はその端部25aが第二の位置決め部材となるダミーチューブ53の端部53aに第二の保護フィルタ27を介在させて接続され、ダミーチューブ53の他端部53bが血液系パネル70に設けられた係止片70cにより脱着可能に固定されている。   The second pressure measurement line 25 is connected to the end portion 53a of the dummy tube 53 whose end portion 25a is the second positioning member with the second protective filter 27 interposed therebetween, and the other end portion of the dummy tube 53 is connected. 53 b is detachably fixed by a locking piece 70 c provided on the blood system panel 70.

即ち、図4に示すように、血液系パネル70は血液系回路2の上下方向及び左右方向の位置決め部材を兼ねる。また、第1、第2の位置決め部材となるダミーチューブ52,53は血液系回路2の上下方向の位置決め部材を兼ねる。また、第1、第2の位置決め部材となるダミーチューブ52,53を係止する係止片70b,70cは血液系回路2の上下方向及び左右方向の位置決め部材を兼ねる。また、採血回路部11の分岐流路21を係止する係止片70aは採血回路部11の上下方向及び左右方向の位置決め部材を兼ねる。   That is, as shown in FIG. 4, the blood system panel 70 also serves as a positioning member in the vertical direction and the horizontal direction of the blood system circuit 2. The dummy tubes 52 and 53 serving as the first and second positioning members also serve as the vertical positioning members of the blood system circuit 2. Further, the locking pieces 70b and 70c for locking the dummy tubes 52 and 53 serving as the first and second positioning members also serve as the positioning members in the vertical and horizontal directions of the blood system circuit 2. Further, the locking piece 70a that locks the branch flow path 21 of the blood collection circuit unit 11 also serves as a positioning member in the vertical direction and the horizontal direction of the blood collection circuit unit 11.

尚、血液系パネル70に設けられた各係止片70a〜70cは、図2に示された液系パネル170に設けられた係止片170a,170bと同様に、血液系パネル70の一部を切り欠いて起立させ、その起立片に更にチューブや端部ソケット等の管体を挟み込んで係止するための切り欠きが設けられたものである。   Each of the locking pieces 70a to 70c provided on the blood system panel 70 is a part of the blood system panel 70 in the same manner as the locking pieces 170a and 170b provided on the liquid system panel 170 shown in FIG. The notch is provided with a notch for sandwiching and locking a tube body such as a tube or an end socket.

図4に示すように、血液系パネル70に設けた方形穴からなる固定部位90を血液浄化装置4の上部に設けられた第一のハンガー部となる突起部分5aに嵌装して固定して第一の結束バンド81,82を解いても、プライミング用の分岐流路21の端部21aが血液系パネル70の右側位置で係止片70aに係止され、ダミーチューブ52,53のそれぞれの端部52b,53bが血液系パネル70の中央位置及び左側位置でそれぞれ係止片70b,70cに係止され、血液系回路2上の各装着部分がその自重により垂下され、血液浄化装置4上の対応部位付近に配置された状態で保持されているため血液系回路2が床に落ちることはない。   As shown in FIG. 4, a fixing portion 90 formed of a square hole provided in the blood system panel 70 is fitted and fixed to a protruding portion 5 a serving as a first hanger portion provided in the upper part of the blood purification device 4. Even when the first binding bands 81 and 82 are released, the end 21a of the priming branch channel 21 is locked to the locking piece 70a at the right position of the blood system panel 70, and the dummy tubes 52 and 53 are respectively connected. The end portions 52b and 53b are locked to the locking pieces 70b and 70c at the center position and the left position of the blood system panel 70, respectively, and each mounting portion on the blood system circuit 2 is suspended by its own weight. The blood system circuit 2 does not fall to the floor because it is held in the state of being arranged in the vicinity of the corresponding part.

従って、図示しない生理食塩液バッグ等に接続されるプライミング用の分岐流路21の端部21aは清潔に保たれ、床等に落下することによって不用意に汚染される恐れがない。加えて、血液系回路2を構成する採血回路部11、返血回路部12等の各回路部及び各ダミーチューブ52,53の長さを適切に選べば、血液系回路2上の装着部分であるピロー部14と、血液ポンプチューブ15と、動脈側ドリップチャンバ16と、静脈側ドリップチャンバ19とは、それぞれ血液浄化装置4上の対応部位である採血陰圧検知器200と、血液ポンプ201と、動脈側ドリップチャンバ固定部位202と、静脈側ドリップチャンバ固定部位203のそれぞれの付近に配置されるように構成することができる。   Therefore, the end portion 21a of the priming branch flow path 21 connected to a physiological saline bag or the like (not shown) is kept clean, and there is no fear of being inadvertently contaminated by dropping on the floor or the like. In addition, if the length of each circuit unit such as the blood collection circuit unit 11 and the blood return circuit unit 12 constituting the blood system circuit 2 and the length of each dummy tube 52, 53 is appropriately selected, the attached portion on the blood system circuit 2 A certain pillow section 14, a blood pump tube 15, an arterial drip chamber 16, and a venous drip chamber 19 are a blood collection negative pressure detector 200 and a blood pump 201, which are corresponding parts on the blood purification device 4, respectively. The arterial drip chamber fixing part 202 and the venous drip chamber fixing part 203 can be arranged in the vicinity of each other.

また、各ダミーチューブ51,52,53を、血液系回路2を構成する採血回路部11、返血回路部12等の各回路部の透明チューブとは異なる色で構成すれば接続作業時に取り外す各ダミーチューブ51,52,53が容易に判別できて作業性に優れる。   Further, if each dummy tube 51, 52, 53 is made of a color different from the transparent tube of each circuit part such as the blood collection circuit part 11 and the blood return circuit part 12 constituting the blood system circuit 2, each of the dummy tubes 51, 52, 53 is removed during connection work. The dummy tubes 51, 52, and 53 can be easily distinguished and have excellent workability.

抗凝固剤導入用の分岐流路22は、抗凝固剤を入れた図示しない注射器型のシリンジに接続され、該シリンジは血液浄化装置4のシリンジポンプ204に装着される。第一の圧力測定ライン23は、端部23aに第一の保護フィルタ26を有し、図4に示す血液浄化装置4の動脈圧圧力計205に接続される。第二の圧力測定ライン25は、端部25aに第二の保護フィルタ27を有し、図4に示す血液浄化装置4の静脈圧圧力計206に接続される。補液導入用の分岐流路24の端部24aは、図5に示す補液回路部102の分岐流路107の端部107aと接続される。   The branch channel 22 for introducing the anticoagulant is connected to a syringe-type syringe (not shown) containing the anticoagulant, and the syringe is attached to the syringe pump 204 of the blood purification apparatus 4. The first pressure measurement line 23 has a first protective filter 26 at the end 23a, and is connected to the arterial pressure manometer 205 of the blood purification apparatus 4 shown in FIG. The second pressure measurement line 25 has a second protective filter 27 at the end 25a, and is connected to the venous pressure gauge 206 of the blood purification apparatus 4 shown in FIG. The end 24a of the branch flow path 24 for introducing replacement fluid is connected to the end 107a of the branch flow path 107 of the replacement fluid circuit section 102 shown in FIG.

図2において、液系回路3は主に軟質チューブからなり、該液系回路3には透析液量計測バッグ161、補液量計測バッグ162、濾過液量計測バッグ163からなる各種軟質バッグが連結されており、該液系回路3が連結された各種軟質バッグは第二の結束バンドとなる透析液系結束バンド181、補液系結束バンド182及び濾過液系結束バンド183により液系パネル170に脱着可能に保持されている。具体的には、液系回路3と軟質バッグは、透析液回路部101が連結された透析液量計測バッグ161と、補液回路部102が連結された補液量計測バッグ162と、濾過液回路部103が連結された濾過液量計測バッグ163との3つの部分からなる。透析液量計測バッグ161、補液量計測バッグ162、濾過液量計測バッグ163は、それぞれ相互に識別可能なようにラベルが付される。なお、持続的血液濾過法(CHF)を行う場合には、透析液回路部101が連結された透析液量計測バッグ161は無くても良く、持続的血液透析法(CHD)を行う場合には、補液回路部102が連結された補液量計測バッグ162は無くても良い。   In FIG. 2, the liquid circuit 3 is mainly composed of a soft tube, and various soft bags including a dialysate volume measurement bag 161, a replacement fluid volume measurement bag 162, and a filtrate volume measurement bag 163 are connected to the liquid circuit 3. The various soft bags to which the liquid circuit 3 is connected can be detached from the liquid system panel 170 by the dialysate system binding band 181, the replacement fluid system binding band 182, and the filtrate system binding band 183, which are the second binding bands. Is held in. Specifically, the liquid system circuit 3 and the soft bag include a dialysate amount measurement bag 161 to which the dialysate circuit portion 101 is connected, a replacement fluid amount measurement bag 162 to which the replacement fluid circuit portion 102 is connected, and a filtrate circuit portion. It consists of three parts, the filtrate amount measuring bag 163 connected to 103. The dialysate volume measurement bag 161, the replacement fluid volume measurement bag 162, and the filtrate volume measurement bag 163 are labeled so that they can be distinguished from each other. In the case of performing continuous hemodialysis (CHF), the dialysate volume measuring bag 161 connected to the dialysate circuit unit 101 may be omitted, and in the case of performing continuous hemodialysis (CHD). The replacement fluid amount measuring bag 162 to which the replacement fluid circuit unit 102 is connected may be omitted.

液系パネル170の形状、材質は、図3に示すように、血液浄化装置4の上部に設けられた第二のハンガー部5bに固定できて液系回路3を固定できるものであれば、どのような形状、材質であっても良いが、平板状で適度の剛性と可撓性を有するポリプロピレン等の硬質プラスチックが好ましい。   As long as the shape and material of the liquid system panel 170 can be fixed to the second hanger part 5b provided on the upper part of the blood purification device 4 and can fix the liquid system circuit 3, as shown in FIG. Such a shape and material may be used, but a hard plastic such as polypropylene having a flat plate shape and appropriate rigidity and flexibility is preferable.

液系パネル170の第二の固定部位190は、血液浄化装置4の上部に設けられた第二のハンガー部5bに固定できる構造であればどのようなものであっても良いが、血液浄化装置4の上部に設けられた第二のハンガー部となる突起部分5bに嵌め込んで固定できる穴が、構造が簡単であり実用的なので好ましい。液系パネル170を固定する血液浄化装置4上の部位は、定位置でなければならない。尚、図2及び図5中の171は液系パネル170を取り扱うためのハンドル穴である。   The second fixing portion 190 of the liquid system panel 170 may be of any structure as long as it can be fixed to the second hanger portion 5b provided on the upper portion of the blood purification device 4. A hole that can be fitted into and fixed to the protruding portion 5b that is the second hanger portion provided on the upper portion of 4 is preferable because the structure is simple and practical. The part on the blood purification apparatus 4 that fixes the liquid system panel 170 must be in a fixed position. 2 and 5, reference numeral 171 denotes a handle hole for handling the liquid system panel 170.

液系回路3と各種軟質バッグは第二の結束バンドによって束ねられて液系パネル170に脱着可能に固定される。第二の結束バンドは、具体的には、図2に示すように、透析液回路部101が連結された透析液量計測バッグ161を束ねる透析液系結束バンド181と、補液回路部102が連結された補液量計測バッグ162を束ねる補液系結束バンド182と、濾過液回路部103が連結された濾過液量計測バッグ163を束ねる濾過液系結束バンド183との3つの部分からなる。   The liquid circuit 3 and various soft bags are bundled by a second binding band and fixed to the liquid panel 170 so as to be detachable. Specifically, as shown in FIG. 2, the second binding band includes a dialysate system binding band 181 that binds the dialysate amount measurement bag 161 to which the dialysate circuit unit 101 is connected, and a replacement fluid circuit unit 102. The replacement fluid binding band 182 that bundles the replacement fluid volume measuring bag 162 and the filtrate binding band 183 that binds the filtrate fluid measurement bag 163 to which the filtrate circuit unit 103 is connected.

図5に示すように、透析液回路部101は、一端側に透析液バッグ164に接続するための端部101aが設けられ、他端側に透析液量計測バッグ161に接続された透析液回路部101上に、血液浄化器6の透析液入口6cに連結する端部105が設けられた分岐流路104を有し、該分岐流路104には透析液ポンプチューブ106が設けられている。透析液バッグ164に接続するための端部101aは液系パネル170に設けられた係止片170aにより係止されて着脱可能に固定されている。   As shown in FIG. 5, the dialysate circuit unit 101 is provided with an end 101a for connection to the dialysate bag 164 on one end side, and a dialysate circuit connected to the dialysate amount measurement bag 161 on the other end side. On the part 101, there is a branch channel 104 provided with an end 105 connected to the dialysate inlet 6 c of the blood purifier 6, and a dialysate pump tube 106 is provided in the branch channel 104. The end portion 101a for connecting to the dialysate bag 164 is locked by a locking piece 170a provided on the liquid system panel 170 and is detachably fixed.

透析液回路部101が連結された透析液量計測バッグ161は、透析液系結束バンド181を解いてそのまま透析液量計測バッグ161を平行移動すれば、図5に示す血液浄化装置4の透析液用重量計207に装着できるように構成されている。この間、透析液バッグ164に接続するための端部101aは係止片170aにより係止されて液系パネル170に固定されているから清潔に保たれ、床等に落下することによって不用意に汚染される恐れはない。透析液ポンプチューブ106は、図3に示す血液浄化装置4の透析液ポンプ208の外周に巻回して装着し、該透析液ポンプ208の回転により透析液ポンプチューブ106をしごいて血液浄化器6の透析液入口6cに透析液が送られる。   The dialysate volume measuring bag 161 to which the dialysate circuit unit 101 is connected can be dialyzed in the blood purification device 4 shown in FIG. It is configured so that it can be attached to the weighing scale 207. During this time, the end 101a for connecting to the dialysate bag 164 is locked by the locking piece 170a and fixed to the liquid system panel 170, so it is kept clean and inadvertently contaminated by falling on the floor or the like. There is no fear of being done. The dialysate pump tube 106 is wound around the outer periphery of the dialysate pump 208 of the blood purification apparatus 4 shown in FIG. 3, and the dialysate pump tube 106 is squeezed by the rotation of the dialysate pump 208 to remove the blood purifier 6. The dialysate is sent to the dialysate inlet 6c.

補液回路部102は、一端側に補液バッグ165に接続するための端部102aが設けられ、他端側に補液量計測バッグ162に接続された補液回路部102上に、図1(b)に示す返血回路部12の補液導入用の分岐流路24の端部24aに連結するための端部107aが設けられた分岐流路107を有し、該分岐流路107には補液ポンプチューブ108が設けられている。補液バッグ165に接続するための端部102aは液系パネル170に設けられた係止片170bにより係止されて着脱可能に固定されている。   The replacement fluid circuit portion 102 is provided with an end portion 102a for connection to the replacement fluid bag 165 on one end side, and on the replacement fluid circuit portion 102 connected to the replacement fluid amount measurement bag 162 on the other end side, as shown in FIG. A branch flow path 107 provided with an end 107a for connection to an end 24a of the branch flow path 24 for introducing a replacement fluid of the blood return circuit section 12 shown in FIG. Is provided. An end portion 102a for connecting to the replacement fluid bag 165 is locked by a locking piece 170b provided on the liquid system panel 170 and is detachably fixed.

補液回路部102が連結された補液量計測バッグ162は、補液系結束バンド182を解いてそのまま補液量計測バッグ162を平行移動すれば、図5に示す血液浄化装置4の補液用重量計209に装着できるように構成されている。この間、補液バッグ165に接続するための端部102aは係止片170bにより係止されて液系パネル170に固定されているから清潔に保たれ、床等に落下することによって不用意に汚染される恐れはない。補液ポンプチューブ108は、図3に示す血液浄化装置4の補液ポンプ210の外周に巻回して装着し、該補液ポンプ210の回転により補液ポンプチューブ108をしごいて分岐流路107の端部107aに、図4に示す端部24aが接続された分岐流路24を介して返血回路部12に補液が送られる。補液は患者から抜いた体液分だけ新たに体液を補充する液である。   When the replacement fluid amount measuring bag 162 connected to the replacement fluid circuit unit 102 is moved through the replacement fluid system binding band 182 and translated as it is, the replacement fluid amount measuring bag 162 becomes the replacement fluid weighing scale 209 of the blood purification device 4 shown in FIG. It is configured so that it can be attached. During this time, the end portion 102a for connecting to the replacement fluid bag 165 is locked by the locking piece 170b and fixed to the liquid system panel 170, so it is kept clean and is inadvertently contaminated by dropping on the floor or the like. There is no fear. The replacement fluid pump tube 108 is wound around the outer periphery of the replacement fluid pump 210 of the blood purification apparatus 4 shown in FIG. 3, and the replacement fluid pump tube 108 is squeezed by the rotation of the replacement fluid pump 210 to end the end 107a of the branch flow path 107. In addition, the replacement fluid is sent to the blood return circuit unit 12 through the branch flow path 24 to which the end 24a shown in FIG. 4 is connected. The replacement fluid is a fluid for newly replenishing the body fluid that has been removed from the patient.

濾過液回路部103は、一端側に排液するための端部113が設けられ、他端側に濾過液量計測バッグ163に接続された濾過液回路部103上に、血液浄化器6の透析液出口6dに連結する端部110が設けられた分岐流路109を有し、該分岐流路109には第三の圧力測定ライン112と濾過液ポンプチューブ111が設けられている。濾過液回路部103の排液するための端部113と、分岐流路109の血液浄化器6の透析液出口6dに接続するための端部110とは、清潔に保つ必要がないから、液系パネル170には固定されていない。   The filtrate circuit portion 103 is provided with an end portion 113 for draining at one end side, and the dialysis of the blood purifier 6 on the filtrate circuit portion 103 connected to the filtrate amount measuring bag 163 at the other end side. The branch channel 109 is provided with an end portion 110 connected to the liquid outlet 6d. The branch channel 109 is provided with a third pressure measurement line 112 and a filtrate pump tube 111. The end portion 113 for draining the filtrate circuit portion 103 and the end portion 110 for connecting to the dialysate outlet 6d of the blood purifier 6 of the branch channel 109 do not need to be kept clean. It is not fixed to the system panel 170.

濾過液回路部103が連結された濾過液量計測バッグ163は、濾過液系結束バンド183を解いてそのまま濾過液量計測バッグ163を平行移動すれば、図5に示す血液浄化装置4の濾過液用重量計211に装着できるように構成されている。濾過液ポンプチューブ111は、図4に示す血液浄化装置4の濾過液ポンプ212の外周に巻回して装着し、該濾過液ポンプ212の回転により濾過液ポンプチューブ111をしごいて血液浄化器6の透析液出口6dから分岐流路109を介して濾過液回路部103に濾過液が送られ外部に排液される。一方、第三の圧力測定ライン112の端部112aは図4に示す血液浄化装置4の濾過圧圧力計213に接続される。   The filtrate measuring bag 163 to which the filtrate circuit unit 103 is connected, if the filtrate binding band 183 is released and the filtrate measuring bag 163 is translated as it is, the filtrate of the blood purification device 4 shown in FIG. It is configured so that it can be attached to the industrial weighing scale 211. The filtrate pump tube 111 is wound around the outer periphery of the filtrate pump 212 of the blood purification apparatus 4 shown in FIG. 4, and the filtrate pump tube 111 is squeezed by the rotation of the filtrate pump 212 to remove blood from the blood purifier 6. The filtrate is sent from the dialysate outlet 6d to the filtrate circuit section 103 via the branch channel 109 and discharged to the outside. On the other hand, the end 112a of the third pressure measurement line 112 is connected to the filtration pressure manometer 213 of the blood purification apparatus 4 shown in FIG.

図2(a)に示すように、液系パネル170には、該液系パネル170側から濾過液回路部103が連結された濾過液量計測バッグ163、補液回路部102が連結された補液量計測バッグ162、透析液回路部101が連結された透析液量計測バッグ161の順に上に重ねて配置されており、上から順に結束バンドを解けば、図5に示す血液浄化装置4の下側から順に透析液用重量計207、補液用重量計209、濾過液用重量計211に順次に装着できるようになっている。   As shown in FIG. 2A, the liquid system panel 170 has a filtrate amount measuring bag 163 connected to the filtrate circuit section 103 from the liquid system panel 170 side, and a replacement fluid volume connected to the replacement liquid circuit section 102. The measurement bag 162 and the dialysate amount measurement bag 161 connected with the dialysate circuit unit 101 are arranged on top of each other in order, and the lower side of the blood purification device 4 shown in FIG. The dialysis fluid weighing scale 207, the replacement fluid weighing scale 209, and the filtrate weighing scale 211 can be sequentially mounted.

図5に示すように、液系パネル170は液系回路3の左右方向の位置決め部材を兼ねる。   As shown in FIG. 5, the liquid system panel 170 also serves as a horizontal positioning member for the liquid circuit 3.

本発明は、血液浄化装置を用いて行う体外循環において、体外循環回路を血液浄化装置に簡便、確実かつ安全に装着するのに有用である。   INDUSTRIAL APPLICABILITY The present invention is useful for attaching an extracorporeal circuit to a blood purification device simply, reliably and safely in extracorporeal circulation performed using the blood purification device.

(a)は本発明の実施形態に係る血液系回路が血液系パネルに保持されて収納された状態を示す模式図、(b)は本発明の実施形態に係る血液系回路の一部が血液系パネルに支持された状態で自重により垂下した様子を示す図である。(A) is a schematic diagram showing a state in which a blood system circuit according to an embodiment of the present invention is held and housed in a blood system panel, and (b) is a part of the blood system circuit according to an embodiment of the present invention. It is a figure which shows a mode that it hung down with dead weight in the state supported by the system panel. (a)は本発明の実施形態に係る液系回路が液系パネルに保持されて収納された状態を示す模式図、(b)は結束バンドを解いて液系回路に連結された各軟質バッグを取り外した様子を示す図である。(A) is a schematic diagram which shows the state by which the liquid circuit which concerns on embodiment of this invention was hold | maintained and stored in the liquid system panel, (b) is each soft bag connected to the liquid circuit by releasing the binding band It is a figure which shows a mode that was removed. 本発明の実施形態に係る体外循環回路が装着される血液浄化装置の外観図である。1 is an external view of a blood purification apparatus to which an extracorporeal circuit according to an embodiment of the present invention is attached. 血液系パネルが血液浄化装置の上部に設けられた第一のハンガー部に固定され、結束バンドを解いて血液系回路の一部が該血液系パネルに支持された状態で自重により垂下されて該血液系回路の各装着部が血液浄化装置の装着部位に位置決めされた様子を示す図である。The blood system panel is fixed to the first hanger part provided on the upper part of the blood purification device, the binding band is released, and a part of the blood system circuit is supported by the blood system panel and is suspended by its own weight. It is a figure which shows a mode that each mounting part of the blood system circuit was positioned by the mounting site | part of the blood purification apparatus. 液系パネルが血液浄化装置の上部に設けられた第二のハンガー部に固定され、結束バンドを解いて液系回路に連結された各軟質バッグを血液浄化装置に装着した様子を示す図である。It is a figure which shows a mode that a liquid system panel was fixed to the 2nd hanger part provided in the upper part of the blood purification apparatus, and each soft bag connected to the liquid system circuit by opening the binding band was attached to the blood purification apparatus. .

1…体外循環回路
2…血液系回路
3…液系回路
4…血液浄化装置
5a,5b…突起部分
6…血液浄化器
6a…血液入口(出口)
6b…血液出口(入口)
6c…透析液入口(出口)/濾過液出口
6d…透析液出口(入口)/濾過液出口
11…採血回路部
12…返血回路部
13…端部
14…ピロー部
15…血液ポンプチューブ
16…動脈側ドリップチャンバ
17,18…端部
19…静脈側ドリップチャンバ
20…端部
21…分岐流路
21a…端部
22…分岐流路
23…圧力測定ライン
23a…端部
24…分岐流路
24a…端部
25…圧力測定ライン
25a…端部
26,27…保護フィルタ
51〜53…ダミーチューブ
52a,52b…端部
53a,53b…端部
70…血液系パネル
70a〜70c…係止片
71…ハンドル穴
81,82…第一の結束バンド
90…固定部位
101…透析液回路部
101a…端部
102…補液回路部
102a…端部
103…濾過液回路部
104…分岐流路
105…端部
106…透析液ポンプチューブ
107…分岐流路
107a…端部
108…補液ポンプチューブ
109…分岐流路
110…端部
111…濾過液ポンプチューブ
112…圧力測定ライン
112a…端部
113…端部
161…透析液量計測バッグ
162…補液量計測バッグ
163…濾過液量計測バッグ
164…透析液バッグ
165…補液バッグ
170…液系パネル
170a,170b…係止片
171…ハンドル穴
181…透析液系結束バンド
182…補液系結束バンド
183…濾過液系結束バンド
190…固定部位
200…採血陰圧検知器
201…血液ポンプ
202…動脈側ドリップチャンバ固定部位
203…静脈側ドリップチャンバ固定部位
204…シリンジポンプ
205…動脈圧圧力計
206…静脈圧圧力計
207…透析液用重量計
208…透析液ポンプ
209…補液用重量計
210…補液ポンプ
211…濾過液用重量計
212…濾過液ポンプ
213…濾過圧圧力計
DESCRIPTION OF SYMBOLS 1 ... Extracorporeal circuit 2 ... Blood system circuit 3 ... Liquid system circuit 4 ... Blood purification apparatus 5a, 5b ... Projection part 6 ... Blood purifier 6a ... Blood inlet (outlet)
6b ... Blood outlet (inlet)
6c ... Dialysate inlet (outlet) / filtrate outlet 6d ... Dialysate outlet (inlet) / filtrate outlet
11 ... Blood collection circuit
12… Blood return circuit
13… End
14… Pillow club
15 ... Blood pump tube
16 ... Arterial drip chamber
17, 18 ... end
19 ... Venous drip chamber
20 ... End
21 ... Branch channel
21a ... end
22 ... Branch channel
23… Pressure measurement line
23a ... end
24 ... Branch channel
24a ... end
25 ... Pressure measurement line
25a ... end
26, 27 ... Protection filter
51-53 ... Dummy tube
52a, 52b ... end
53a, 53b ... end
70 ... Blood system panel
70a-70c ... locking piece
71 ... handle hole
81, 82 ... The first unity band
90 ... Fixed part
101 ... Dialysate circuit
101a ... End
102 ... Fluid replacement circuit
102a ... End
103 ... Filtrate circuit
104 ... Branch channel
105… End
106 ... dialysate pump tube
107 ... Branch channel
107a ... End
108… Hydraulic pump tube
109 ... Branch channel
110… End
111 ... filtrate pump tube
112 ... Pressure measurement line
112a ... End
113… End
161 ... Dialysate measurement bag
162… Replacement fluid measurement bag
163 ... Filtrate measurement bag
164 ... Dialysate bag
165 ... Fluid replacement bag
170 ... Liquid panel
170a, 170b ... locking piece
171 ... handle hole
181 ... Dialysate system binding band
182 ... Replacement fluid system band
183 ... Filtrate binding band
190 ... Fixed part
200 ... Negative blood pressure detector
201 ... Blood pump
202 ... Arterial drip chamber fixation site
203 ... Venus side drip chamber fixing part
204 ... Syringe pump
205 ... Arterial pressure and pressure gauge
206 ... Venous pressure gauge
207 ... Weigh scale for dialysate
208… dialysate pump
209 ... Replacement weighing scale
210… Hydraulic pump
211 ... Weighing scale for filtrate
212 ... Filtrate pump
213 ... Filtration pressure gauge

Claims (8)

軟質チューブからなる血液系回路を含む血液浄化装置用の体外循環回路であって、
前記血液系回路は第一の結束バンドによって束ねられて血液系パネルに脱着可能に保持され、
前記血液系パネルは前記血液浄化装置の上部に設けられた第一のハンガー部に固定するための第一の固定部位を有し、
前記血液系回路は、前記血液系パネルを前記第一の固定部位を介して前記血液浄化装置の上部に設けられた前記第一のハンガー部に固定し、前記第一の結束バンドを解くと、前記血液系回路上の各装着部分がその自重により垂下された状態で前記血液浄化装置上の対応部位付近に配置されるように構成されていることを特徴とする体外循環回路。
An extracorporeal circuit for a blood purification apparatus including a blood system circuit composed of a soft tube,
The blood system circuit is bundled by a first binding band and is detachably held on the blood system panel,
The blood system panel has a first fixing part for fixing to a first hanger part provided on the upper part of the blood purification device,
The blood system circuit fixes the blood system panel to the first hanger part provided on the upper part of the blood purification device via the first fixing part, and when the first binding band is released , An extracorporeal circulation circuit configured to be disposed in the vicinity of a corresponding portion on the blood purification apparatus in a state where each mounting portion on the blood system circuit is suspended by its own weight.
前記血液系回路は、患者から採血された血液を血液浄化器に送る採血回路部と、前記血液浄化器の血液を患者に戻す返血回路部と、前記採血回路部と前記返血回路部とを接続する接続部材とからなり、
前記採血回路部は、一端側が患者に接続するための端部であり、他端側が前記血液浄化器の血液入口に接続するための端部である採血回路部上に、プライミング用の分岐流路と、ピロー部と、血液ポンプチューブと、抗凝固剤導入用の分岐流路と、第一の圧力測定ラインが連結された動脈側ドリップチャンバが配置され、
前記プライミング用の分岐流路の端部は前記血液系パネルに脱着可能に固定され、
前記第一の圧力測定ラインは、端部が前記血液系パネルに固定された第一の位置決め部材に接続され、
前記返血回路部は、一端側が前記血液浄化器の血液出口に接続するための端部であり、他端側が患者に接続するための端部である返血回路部上に、補液導入用の分岐流路と、第二の圧力測定ラインが連結された静脈側ドリップチャンバが配置され、
前記第二の圧力測定ラインは、端部が前記血液系パネルに固定された第二の位置決め部材に接続され、
前記接続部材は、前記採血回路部の前記血液浄化器の血液入口に接続するための端部と、前記返血回路部の前記血液浄化器の血液出口に接続するための端部とを接続し、
前記第一の結束バンドは、前記採血回路部を束ねる採血回路部結束バンドと、前記返血回路部を束ねる返血回路部結束バンドとを含み、
前記血液系回路は、前記採血回路部結束バンドと前記返血回路部結束バンドとを解くと、前記採血回路部上の前記ピロー部は前記血液浄化装置の採血陰圧検知器付近に配置され、前記血液ポンプチューブは血液ポンプ付近に配置され、前記動脈側ドリップチャンバは動脈側ドリップチャンバ固定部位付近に配置され、前記静脈側ドリップチャンバは静脈側ドリップチャンバ固定部位付近に配置されることを特徴とする請求項に記載の体外循環回路。
The blood system circuit includes a blood collection circuit unit that sends blood collected from a patient to a blood purifier, a blood return circuit unit that returns the blood of the blood purifier to the patient, the blood collection circuit unit, and the blood return circuit unit. And a connecting member for connecting
The blood collection circuit section has a branch flow channel for priming on the blood collection circuit section, one end of which is an end for connecting to a patient and the other end is an end for connecting to the blood inlet of the blood purifier. And an arterial drip chamber to which a pillow part, a blood pump tube, a branch channel for introducing an anticoagulant, and a first pressure measurement line are connected,
An end of the branch channel for priming is detachably fixed to the blood system panel,
The first pressure measurement line is connected to a first positioning member whose end is fixed to the blood system panel,
The blood return circuit part has one end side connected to the blood outlet of the blood purifier and the other end side connected to the patient. A venous drip chamber connected to the branch flow path and the second pressure measurement line is disposed,
The second pressure measurement line is connected to a second positioning member whose end is fixed to the blood system panel,
The connection member connects an end of the blood collection circuit unit for connection to the blood inlet of the blood purifier and an end of the blood return circuit unit for connection to the blood outlet of the blood purifier. ,
The first binding band includes a blood collection circuit unit binding band for binding the blood collection circuit unit, and a blood return circuit unit binding band for binding the blood return circuit unit,
When the blood system circuit unwraps the blood collection circuit unit binding band and the blood return circuit unit binding band, the pillow unit on the blood collection circuit unit is disposed in the vicinity of the blood negative pressure detector of the blood purification device, The blood pump tube is disposed in the vicinity of the blood pump, the arterial drip chamber is disposed in the vicinity of the arterial drip chamber fixing portion, and the venous drip chamber is disposed in the vicinity of the venous drip chamber fixing portion. The extracorporeal circuit according to claim 1 .
前記血液浄化装置用の体外循環回路は更に軟質チューブからなる液系回路が連結された軟質バッグを含み、
該液系回路及び軟質バッグは第二の結束バンドによって束ねられて液系パネルに脱着可能に保持され、
前記液系パネルは前記血液浄化装置の上部に設けられた第二のハンガー部に固定するための第二の固定部位を有し、
前記液系回路が連結された軟質バッグは、前記液系パネルを前記第二の固定部位を介して前記血液浄化装置の上部に設けられた前記第二のハンガー部に固定して前記第二の結束バンドを解き、前記軟質バッグをそのまま平行移動すれば前記血液浄化装置の所定の位置に設置できるように構成されていることを特徴とする請求項1または請求項2に記載の体外循環回路。
The extracorporeal circuit for the blood purification apparatus further includes a soft bag to which a liquid circuit composed of a soft tube is connected,
The liquid circuit and the soft bag are bundled by a second binding band and are detachably held on the liquid panel.
The liquid system panel has a second fixing part for fixing to a second hanger part provided on the upper part of the blood purification device,
The soft bag to which the liquid system circuit is connected is configured such that the liquid system panel is fixed to the second hanger portion provided on the blood purification device via the second fixing portion. 3. The extracorporeal circuit according to claim 1 , wherein the extracorporeal circulation circuit is configured to be installed at a predetermined position of the blood purification device by releasing the binding band and translating the soft bag as it is.
前記軟質チューブからなる液系回路が連結された軟質バッグとして濾過液回路部が連結された濾過液量計測バッグを有し、
前記濾過液回路部は、一端側が排液するための端部であり、他端側が前記濾過液量計測バッグに接続された前記濾過液回路部上に、血液浄化器の透析液出口に連結する分岐流路を有し、該分岐流路には第三の圧力測定ラインと濾過液ポンプチューブが設けられており、
前記第二の結束バンドは、前記濾過液回路部と前記濾過液量計測バッグとを束ねる濾過液系結束バンドを含むことを特徴とする請求項に記載の体外循環回路。
A filtrate amount measurement bag having a filtrate circuit portion connected as a soft bag to which a liquid circuit composed of the soft tube is connected,
The filtrate circuit portion is an end portion for draining one end side, and the other end side is connected to the dialysate outlet of the blood purifier on the filtrate circuit portion connected to the filtrate amount measurement bag. A branch flow path, the branch flow path is provided with a third pressure measurement line and a filtrate pump tube;
4. The extracorporeal circuit according to claim 3 , wherein the second binding band includes a filtrate-based binding band that bundles the filtrate circuit section and the filtrate amount measurement bag.
前記軟質チューブからなる液系回路が連結された軟質バッグとして透析液回路部が連結された透析液量計測バッグを有し、
前記透析液回路部は、一端側が透析液バッグに接続するための端部であり、他端側が前記透析液量計測バッグに接続された前記透析液回路部上に、血液浄化器の透析液入口に連結する分岐流路を有し、該分岐流路には透析液ポンプチューブが設けられており、
前記第二の結束バンドは、前記透析液回路部と前記透析液量計測バッグとを束ねる透析液系結束バンドを含むことを特徴とする請求項に記載の体外循環回路。
A dialysis fluid amount measurement bag connected to a dialysis fluid circuit unit as a soft bag to which a fluid circuit composed of the soft tube is connected;
The dialysate circuit part has an end part for connecting to the dialysate bag, and the other end part is connected to the dialysate circuit part connected to the dialysate amount measurement bag, and the dialysate inlet of the blood purifier A branch channel connected to the dial channel, and a dialysate pump tube is provided in the branch channel,
5. The extracorporeal circuit according to claim 4 , wherein the second binding band includes a dialysate-based binding band that binds the dialysate circuit section and the dialysate amount measurement bag.
前記軟質チューブからなる液系回路が連結された軟質バッグとして補液回路部が連結された補液量計測バッグを有し、
前記補液回路部は、一端側が補液バッグに接続するための端部であり、他端側が前記補液量計測バッグに接続された前記補液回路部上に、血液浄化器の血液を患者に戻す返血回路部の補液導入用の分岐流路に連結するための分岐流路を有し、該分岐流路には補液ポンプチューブが設けられており、
前記第二の結束バンドは、前記補液回路部と前記補液量計測バッグとを束ねる補液系結束バンドを含むことを特徴とする請求項または請求項に記載の体外循環回路。
Having a replacement fluid amount measurement bag connected to a replacement fluid circuit unit as a soft bag to which a liquid circuit composed of the soft tube is connected;
The replacement fluid circuit portion is an end portion for connecting one end side to the replacement fluid bag, and the other end side returns blood to the patient on the replacement fluid circuit portion connected to the replacement fluid amount measurement bag. A branch passage for connecting to a branch passage for introducing a replacement fluid in the circuit section, and a replacement fluid pump tube is provided in the branch passage;
Said second binding band is extracorporeal circuit according to claim 4 or claim 5, characterized in that it comprises a replacement fluid system binding band to bundle and the replacement fluid weight measuring bag and the replacement fluid circuit portion.
前記透析液バッグに接続するための端部が前記液系パネルに脱着可能に固定されたことを特徴とする請求項に記載の体外循環回路。 6. The extracorporeal circuit according to claim 5 , wherein an end for connecting to the dialysate bag is detachably fixed to the liquid system panel. 前記補液バッグに接続するための端部が前記液系パネルに脱着可能に固定されたことを特徴とする請求項に記載の体外循環回路。 The extracorporeal circuit according to claim 6 , wherein an end portion for connection to the replacement fluid bag is detachably fixed to the liquid system panel.
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