JP7631502B2 - エボラウイルスワクチンに関連する組成物及び方法 - Google Patents
エボラウイルスワクチンに関連する組成物及び方法 Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/473—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used alpha-Glycoproteins
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6068—Other bacterial proteins, e.g. OMP
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/735—Fusion polypeptide containing domain for protein-protein interaction containing a domain for self-assembly, e.g. a viral coat protein (includes phage display)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/14011—Filoviridae
- C12N2760/14111—Ebolavirus, e.g. Zaire ebolavirus
- C12N2760/14122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/14011—Filoviridae
- C12N2760/14111—Ebolavirus, e.g. Zaire ebolavirus
- C12N2760/14134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Toxicology (AREA)
- General Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063063530P | 2020-08-10 | 2020-08-10 | |
| US63/063,530 | 2020-08-10 | ||
| PCT/US2021/045178 WO2022035739A2 (en) | 2020-08-10 | 2021-08-09 | Compositions and methods related to ebola virusvaccines |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023537518A JP2023537518A (ja) | 2023-09-01 |
| JP2023537518A5 JP2023537518A5 (https=) | 2024-12-27 |
| JP7631502B2 true JP7631502B2 (ja) | 2025-02-18 |
Family
ID=80114705
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023509430A Active JP7631502B2 (ja) | 2020-08-10 | 2021-08-09 | エボラウイルスワクチンに関連する組成物及び方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US11305004B2 (https=) |
| EP (1) | EP4192500A4 (https=) |
| JP (1) | JP7631502B2 (https=) |
| CN (1) | CN116472278A (https=) |
| AU (1) | AU2021324954A1 (https=) |
| CA (1) | CA3190148A1 (https=) |
| IL (1) | IL300527A (https=) |
| MX (1) | MX2023001433A (https=) |
| WO (1) | WO2022035739A2 (https=) |
| ZA (1) | ZA202301221B (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024130061A1 (en) * | 2022-12-16 | 2024-06-20 | Cz Biohub Sf, Llc | Immunogenic ebolavirus fusion proteins and related methods |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016145385A2 (en) | 2015-03-11 | 2016-09-15 | Integrated Biotherapeutics, Inc. | Pan-ebola and pan-filovirus protective epitopes, antibodies, and antibody cocktails |
| WO2017172622A1 (en) | 2016-03-28 | 2017-10-05 | Integrated Biotherapeutics, Inc. | Pan filovirus vaccine compositions and methods of making |
| US20180105580A1 (en) | 2015-02-10 | 2018-04-19 | The Secretary Of State For Health | Filovirus therapy |
| WO2019241483A1 (en) | 2018-06-13 | 2019-12-19 | The Scripps Research Institute | Nanoparticle vaccines with novel structural components |
| WO2020035497A1 (en) | 2018-08-13 | 2020-02-20 | Janssen Vaccines & Prevention B.V. | Stabilized filovirus glycoprotein trimers |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7211378B2 (en) * | 2002-01-31 | 2007-05-01 | Wisconsin Alumni Research Foundation | Filovirus vectors and noninfectious filovirus-based particles |
| KR20260047644A (ko) * | 2017-03-30 | 2026-04-08 | 더 유니버서티 어브 퀸슬랜드 | 키메라 분자 및 그의 용도 |
| CN107034225B (zh) * | 2017-05-04 | 2020-01-17 | 中国人民解放军军事医学科学院生物工程研究所 | 制备埃博拉病毒糖蛋白与基质蛋白融合突变体的方法 |
-
2021
- 2021-08-09 WO PCT/US2021/045178 patent/WO2022035739A2/en not_active Ceased
- 2021-08-09 EP EP21856499.5A patent/EP4192500A4/en active Pending
- 2021-08-09 CN CN202180069178.XA patent/CN116472278A/zh active Pending
- 2021-08-09 CA CA3190148A patent/CA3190148A1/en active Pending
- 2021-08-09 MX MX2023001433A patent/MX2023001433A/es unknown
- 2021-08-09 JP JP2023509430A patent/JP7631502B2/ja active Active
- 2021-08-09 US US17/397,340 patent/US11305004B2/en active Active
- 2021-08-09 AU AU2021324954A patent/AU2021324954A1/en not_active Abandoned
- 2021-08-09 IL IL300527A patent/IL300527A/en unknown
-
2022
- 2022-04-07 US US17/715,658 patent/US11872277B2/en active Active
-
2023
- 2023-01-30 ZA ZA2023/01221A patent/ZA202301221B/en unknown
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20180105580A1 (en) | 2015-02-10 | 2018-04-19 | The Secretary Of State For Health | Filovirus therapy |
| WO2016145385A2 (en) | 2015-03-11 | 2016-09-15 | Integrated Biotherapeutics, Inc. | Pan-ebola and pan-filovirus protective epitopes, antibodies, and antibody cocktails |
| WO2017172622A1 (en) | 2016-03-28 | 2017-10-05 | Integrated Biotherapeutics, Inc. | Pan filovirus vaccine compositions and methods of making |
| WO2019241483A1 (en) | 2018-06-13 | 2019-12-19 | The Scripps Research Institute | Nanoparticle vaccines with novel structural components |
| WO2020035497A1 (en) | 2018-08-13 | 2020-02-20 | Janssen Vaccines & Prevention B.V. | Stabilized filovirus glycoprotein trimers |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2022035739A3 (en) | 2022-03-24 |
| US11872277B2 (en) | 2024-01-16 |
| US11305004B2 (en) | 2022-04-19 |
| US20220040286A1 (en) | 2022-02-10 |
| US20220305109A1 (en) | 2022-09-29 |
| CN116472278A (zh) | 2023-07-21 |
| IL300527A (en) | 2023-04-01 |
| CA3190148A1 (en) | 2022-02-17 |
| ZA202301221B (en) | 2024-05-30 |
| MX2023001433A (es) | 2023-03-06 |
| EP4192500A4 (en) | 2025-01-01 |
| WO2022035739A2 (en) | 2022-02-17 |
| EP4192500A2 (en) | 2023-06-14 |
| AU2021324954A1 (en) | 2023-02-23 |
| JP2023537518A (ja) | 2023-09-01 |
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