JP7597380B2 - 対側眼へのａａｖ遺伝子治療の逐次的硝子体内投与 - Google Patents
対側眼へのａａｖ遺伝子治療の逐次的硝子体内投与 Download PDFInfo
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| US62/839,457 | 2019-04-26 | ||
| PCT/US2020/020929 WO2020180951A1 (en) | 2019-03-04 | 2020-03-04 | Sequential intravitreal administration of aav gene therapy to contralateral eyes |
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| CA3196439A1 (en) * | 2020-11-10 | 2022-05-19 | Avirmax, Inc. | Engineered viral capsids and methods of use |
| CA3210368A1 (en) * | 2021-04-09 | 2022-10-13 | Shengjiang Liu | Compositions and methods for ocular transgene expression |
| CN118715236A (zh) * | 2022-02-17 | 2024-09-27 | 九天生物医药(上海)有限公司 | 具有经修饰的aav衣壳多肽的重组腺相关病毒 |
| EP4536694A1 (en) | 2022-06-07 | 2025-04-16 | Adverum Biotechnologies, Inc. | Melanopsin variants for vision restoration |
| WO2024168252A2 (en) * | 2023-02-10 | 2024-08-15 | Yale University | Use of inhibitors of vegf-c signaling for inhibiting immune responses and increasing gene therapy efficacy |
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| WO2017190125A1 (en) | 2016-04-29 | 2017-11-02 | Adverum Biotechnologies, Inc. | Evasion of neutralizing antibodies by a recombinant adeno-associated virus |
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| US6962815B2 (en) * | 2001-01-05 | 2005-11-08 | Children's Hopital Inc. | AAV2 vectors and methods |
| US9441244B2 (en) | 2003-06-30 | 2016-09-13 | The Regents Of The University Of California | Mutant adeno-associated virus virions and methods of use thereof |
| US9725485B2 (en) * | 2012-05-15 | 2017-08-08 | University Of Florida Research Foundation, Inc. | AAV vectors with high transduction efficiency and uses thereof for gene therapy |
| LT3254703T (lt) | 2011-04-22 | 2020-05-25 | The Regents Of The University Of California | Adenoasocijuoto viruso virionai su variantine kapside ir jų panaudojimo būdai |
| TWI775096B (zh) | 2012-05-15 | 2022-08-21 | 澳大利亞商艾佛蘭屈澳洲私營有限公司 | 使用腺相關病毒(aav)sflt-1治療老年性黃斑部退化(amd) |
| LT3137497T (lt) * | 2014-05-02 | 2021-07-26 | Genzyme Corporation | Aav vektoriai, skirti tinklainės ir cns genų terapijai |
| KR20170137730A (ko) * | 2015-03-02 | 2017-12-13 | 애드베룸 바이오테크놀로지스, 인코포레이티드 | 망막 추상체에 폴리뉴클레오타이드의 유리체 내 전달을 위한 조성물 및 방법 |
| PT3795181T (pt) * | 2016-06-16 | 2025-11-05 | Adverum Biotechnologies Inc | Tratamento de dmi com utilização da variante aav2 com aflibercept |
| EP3528785A4 (en) * | 2016-10-19 | 2020-12-02 | Adverum Biotechnologies, Inc. | MODIFIED AAV CASPIDS AND USES THEREOF |
| AU2018227483A1 (en) * | 2017-02-28 | 2019-09-12 | Adverum Biotechnologies, Inc. | Modified AAV capsids and uses thereof |
| KR102616820B1 (ko) | 2017-03-17 | 2023-12-21 | 애드베룸 바이오테크놀로지스, 인코포레이티드 | 향상된 유전자 발현을 위한 조성물 및 방법 |
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| WO2017190125A1 (en) | 2016-04-29 | 2017-11-02 | Adverum Biotechnologies, Inc. | Evasion of neutralizing antibodies by a recombinant adeno-associated virus |
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| Title |
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| GRISHANIN, R. et al.，Mol Ther，2019年01月，Vol. 27, No. 1，pp. 118-129 |
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| JP2022522776A (ja) | 2022-04-20 |
| KR20210135267A (ko) | 2021-11-12 |
| AU2020231505A8 (en) | 2021-09-02 |
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| AU2020231505A1 (en) | 2021-08-19 |
| EP3934698A1 (en) | 2022-01-12 |
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