JP7596259B2 - プログラム可能な塩基エディターシステムを用いて単一ヌクレオチド多型を編集する方法 - Google Patents

プログラム可能な塩基エディターシステムを用いて単一ヌクレオチド多型を編集する方法 Download PDF

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JP7596259B2
JP7596259B2 JP2021513765A JP2021513765A JP7596259B2 JP 7596259 B2 JP7596259 B2 JP 7596259B2 JP 2021513765 A JP2021513765 A JP 2021513765A JP 2021513765 A JP2021513765 A JP 2021513765A JP 7596259 B2 JP7596259 B2 JP 7596259B2
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protein
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JPWO2019217944A5 (enExample
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デイビッド ブライソン、
ジョン エヴァンス、
マイケル パッカー、
ジェイソン マイケル ゲールケ、
ナタリー ペトロシャン、
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ビーム セラピューティクス インク.
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JP2021513765A 2018-05-11 2019-05-11 プログラム可能な塩基エディターシステムを用いて単一ヌクレオチド多型を編集する方法 Active JP7596259B2 (ja)

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US201862670588P 2018-05-11 2018-05-11
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US201862780838P 2018-12-17 2018-12-17
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US201962817986P 2019-03-13 2019-03-13
US62/817,986 2019-03-13
PCT/US2019/031899 WO2019217944A1 (en) 2018-05-11 2019-05-11 Methods of editing single nucleotide polymorphism using programmable base editor systems

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JP2024095618A Pending JP2024147545A (ja) 2018-05-11 2024-06-13 プログラム可能な塩基エディターシステムを使用して単一ヌクレオチド多型を編集する方法
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US9944912B2 (en) 2015-03-03 2018-04-17 The General Hospital Corporation Engineered CRISPR-Cas9 nucleases with altered PAM specificity
US11932856B2 (en) 2017-03-03 2024-03-19 The Regents Of The University Of California RNA targeting of mutations via suppressor tRNAs and deaminases
EP3633034A4 (en) * 2017-05-31 2021-03-24 The University Of Tokyo MODIFIED Cas9 PROTEIN AND USE THEREOF
CA3073448A1 (en) 2017-08-23 2019-02-28 The General Hospital Corporation Engineered crispr-cas9 nucleases with altered pam specificity
WO2019111258A1 (en) * 2017-12-07 2019-06-13 Ramot At Tel-Aviv University Ltd. Treatment for parkinsonian patients with mutations in the lrrk2 gene
WO2019178427A1 (en) 2018-03-14 2019-09-19 Arbor Biotechnologies, Inc. Novel crispr dna targeting enzymes and systems
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