JP7585214B2 - Ｂ型肝炎ウイルス感染のためのＲＮＡｉ薬 - Google Patents

Ｂ型肝炎ウイルス感染のためのＲＮＡｉ薬 Download PDF

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JP7585214B2
JP7585214B2 JP2021546213A JP2021546213A JP7585214B2 JP 7585214 B2 JP7585214 B2 JP 7585214B2 JP 2021546213 A JP2021546213 A JP 2021546213A JP 2021546213 A JP2021546213 A JP 2021546213A JP 7585214 B2 JP7585214 B2 JP 7585214B2
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administered
seq
sequence
hbv
dose
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JP2022521155A (ja
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ディー． ギブン，ブルース
シー． ハミルトン，ジェイムス
シュルエップ，トーマス
グローリア ボーモント，マリア
レンズ，オリバー
コーネリス マリエ カルメイジャー，ロナルド
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GlaxoSmithKline Intellectual Property No 3 Ltd
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    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
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    • A61K31/66—Phosphorus compounds
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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JP2021546213A 2019-02-07 2020-02-07 Ｂ型肝炎ウイルス感染のためのＲＮＡｉ薬 Active JP7585214B2 (ja)

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JP2024122919A JP7763907B2 (ja) 2019-02-07 2024-07-30 Ｂ型肝炎ウイルス感染のためのＲＮＡｉ薬

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201962802614P 2019-02-07 2019-02-07
US62/802,614 2019-02-07
US201962853659P 2019-05-28 2019-05-28
US62/853,659 2019-05-28
US201962932315P 2019-11-07 2019-11-07
US62/932,315 2019-11-07
PCT/US2020/017264 WO2020163747A1 (en) 2019-02-07 2020-02-07 Rnai agents for hepatitis b virus infection

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JP7585214B2 true JP7585214B2 (ja) 2024-11-18

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EP (2) EP3920884B1 (cg-RX-API-DMAC10.html)
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KR (1) KR20210130736A (cg-RX-API-DMAC10.html)
CN (1) CN113507920A (cg-RX-API-DMAC10.html)
AU (1) AU2020219355A1 (cg-RX-API-DMAC10.html)
BR (1) BR112021015361A2 (cg-RX-API-DMAC10.html)
CA (1) CA3129261A1 (cg-RX-API-DMAC10.html)
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024153797A (ja) * 2019-02-07 2024-10-29 アローヘッド ファーマシューティカルズ インコーポレイテッド Ｂ型肝炎ウイルス感染のためのＲＮＡｉ薬

Families Citing this family (12)

* Cited by examiner, † Cited by third party
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CN115957337A (zh) 2015-08-07 2023-04-14 箭头药业股份有限公司 乙型肝炎病毒感染的RNAi疗法
JOP20190015A1 (ar) 2016-08-04 2019-02-04 Arrowhead Pharmaceuticals Inc عوامل (ار ان ايه آي) لعدوى فيروس الالتهاب الكبدي الوبائي ب
EA202091513A1 (ru) 2017-12-19 2020-09-09 Янссен Сайенсиз Айрлэнд Анлимитед Компани Вакцины против вируса гепатита b (hbv) и их применение
EP4168547A1 (en) * 2020-06-22 2023-04-26 Janssen Pharmaceuticals, Inc. Compositions and methods for treatment of hepatitis d virus infection
WO2022078479A1 (en) * 2020-10-16 2022-04-21 Janssen Pharmaceuticals, Inc. Combination therapy for treating hepatitis b virus infection
TW202245809A (zh) * 2020-12-18 2022-12-01 美商詹森藥物公司 用於治療b型肝炎病毒感染之組合療法
KR102798766B1 (ko) * 2020-12-18 2025-04-23 올릭스 주식회사 HBV 발현을 억제하는 RNAi 제제 및 이의 용도
WO2022152869A1 (en) * 2021-01-15 2022-07-21 Janssen Sciences Ireland Unlimited Company Use of oligonucleotides for individuals with hepatic impairment
CN117616121A (zh) * 2021-07-09 2024-02-27 葛兰素史密斯克莱知识产权(第3号)有限公司 寡核苷酸用于具有肾脏损伤的个体的用途
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