JP7579844B2 - 非定型スプリットインテインおよびそれらの使用 - Google Patents

非定型スプリットインテインおよびそれらの使用 Download PDF

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Publication number
JP7579844B2
JP7579844B2 JP2022513402A JP2022513402A JP7579844B2 JP 7579844 B2 JP7579844 B2 JP 7579844B2 JP 2022513402 A JP2022513402 A JP 2022513402A JP 2022513402 A JP2022513402 A JP 2022513402A JP 7579844 B2 JP7579844 B2 JP 7579844B2
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Japan
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fragment
seq
split intein
interest
terminus
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Japanese (ja)
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JP2022552598A5 (https=
JP2022552598A (ja
Inventor
トム、ダブリュー．ミューア
アダム、スティーブンズ
ヨーゼフ、グラムスパッハー
デイビッド、カウバーン
ジリッダー、セカール
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Princeton University
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Princeton University
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
    • C07K1/026—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution by fragment condensation in solution
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2022513402A 2019-08-28 2019-08-28 非定型スプリットインテインおよびそれらの使用 Active JP7579844B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024109107A JP2024156675A (ja) 2019-08-28 2024-07-05 非定型スプリットインテインおよびそれらの使用

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2019/048508 WO2021040703A1 (en) 2019-08-28 2019-08-28 Atypical split inteins and uses thereof

Related Child Applications (1)

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JP2024109107A Division JP2024156675A (ja) 2019-08-28 2024-07-05 非定型スプリットインテインおよびそれらの使用

Publications (3)

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JP2022552598A JP2022552598A (ja) 2022-12-19
JP2022552598A5 JP2022552598A5 (https=) 2022-12-27
JP7579844B2 true JP7579844B2 (ja) 2024-11-08

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ID=74684576

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JP2022513402A Active JP7579844B2 (ja) 2019-08-28 2019-08-28 非定型スプリットインテインおよびそれらの使用
JP2024109107A Withdrawn JP2024156675A (ja) 2019-08-28 2024-07-05 非定型スプリットインテインおよびそれらの使用

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JP2024109107A Withdrawn JP2024156675A (ja) 2019-08-28 2024-07-05 非定型スプリットインテインおよびそれらの使用

Country Status (5)

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US (1) US20220275027A1 (https=)
JP (2) JP7579844B2 (https=)
AU (1) AU2019463636A1 (https=)
CA (1) CA3152679A1 (https=)
WO (1) WO2021040703A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN120569628A (zh) 2023-01-10 2025-08-29 核蛋白有限公司 蛋白聚集测定

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015086825A1 (en) 2013-12-12 2015-06-18 Westfälische Wilhelms-Universität Münster Atypical inteins

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6562576B2 (en) * 2001-01-04 2003-05-13 Myriad Genetics, Inc. Yeast two-hybrid system and use thereof
EP3431497B1 (en) * 2012-06-27 2022-07-27 The Trustees of Princeton University Split inteins, conjugates and uses thereof
US10087213B2 (en) * 2013-01-11 2018-10-02 The Texas A&M University System Intein mediated purification of protein
PT3408292T (pt) * 2016-01-29 2023-07-19 Univ Princeton Inteínas divididas com excecional atividade de splicing
EP3885440A1 (en) * 2020-03-26 2021-09-29 Splicebio, S.L. Split inteins and their uses

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015086825A1 (en) 2013-12-12 2015-06-18 Westfälische Wilhelms-Universität Münster Atypical inteins

Also Published As

Publication number Publication date
US20220275027A1 (en) 2022-09-01
CA3152679A1 (en) 2021-03-04
JP2024156675A (ja) 2024-11-06
JP2022552598A (ja) 2022-12-19
AU2019463636A1 (en) 2022-03-17
WO2021040703A1 (en) 2021-03-04

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