JP7537074B2 - Cd47を活性化する作用物質およびその炎症治療における使用 - Google Patents

Cd47を活性化する作用物質およびその炎症治療における使用 Download PDF

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JP7537074B2
JP7537074B2 JP2018559205A JP2018559205A JP7537074B2 JP 7537074 B2 JP7537074 B2 JP 7537074B2 JP 2018559205 A JP2018559205 A JP 2018559205A JP 2018559205 A JP2018559205 A JP 2018559205A JP 7537074 B2 JP7537074 B2 JP 7537074B2
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tsp1
htra1
peptide
inflammation
gly
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JP2019521963A5 (enExample
JP2019521963A (ja
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セヌラウブ,フロライン
ハウセット,ミシェル
グイロンニーウ,グザビエ
サヘル,ホセ-アラン
カロヤン,フィリップ
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Institut National de la Sante et de la Recherche Medicale INSERM
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2018559205A 2016-05-10 2017-05-10 Cd47を活性化する作用物質およびその炎症治療における使用 Active JP7537074B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2022035726A JP2022078244A (ja) 2016-05-10 2022-03-08 Cd47を活性化する作用物質およびその炎症治療における使用
JP2023180474A JP2023179752A (ja) 2016-05-10 2023-10-19 Cd47を活性化する作用物質およびその炎症治療における使用

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP16169072 2016-05-10
EP16169072.2 2016-05-10
EP17154452.1 2017-02-02
EP17154452 2017-02-02
PCT/EP2017/061151 WO2017194586A1 (en) 2016-05-10 2017-05-10 Agents that activate cd47 and their use in the treatment of inflammation

Related Child Applications (2)

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JP2022035726A Division JP2022078244A (ja) 2016-05-10 2022-03-08 Cd47を活性化する作用物質およびその炎症治療における使用
JP2023180474A Division JP2023179752A (ja) 2016-05-10 2023-10-19 Cd47を活性化する作用物質およびその炎症治療における使用

Publications (3)

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JP2019521963A JP2019521963A (ja) 2019-08-08
JP2019521963A5 JP2019521963A5 (enExample) 2020-05-07
JP7537074B2 true JP7537074B2 (ja) 2024-08-21

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JP2018559205A Active JP7537074B2 (ja) 2016-05-10 2017-05-10 Cd47を活性化する作用物質およびその炎症治療における使用
JP2022035726A Pending JP2022078244A (ja) 2016-05-10 2022-03-08 Cd47を活性化する作用物質およびその炎症治療における使用
JP2023180474A Pending JP2023179752A (ja) 2016-05-10 2023-10-19 Cd47を活性化する作用物質およびその炎症治療における使用

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JP2022035726A Pending JP2022078244A (ja) 2016-05-10 2022-03-08 Cd47を活性化する作用物質およびその炎症治療における使用
JP2023180474A Pending JP2023179752A (ja) 2016-05-10 2023-10-19 Cd47を活性化する作用物質およびその炎症治療における使用

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US (1) US11142548B2 (enExample)
EP (1) EP3454884B1 (enExample)
JP (3) JP7537074B2 (enExample)
CA (1) CA3023802C (enExample)
WO (1) WO2017194586A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3023802C (en) * 2016-05-10 2025-02-04 Inserm (Institut De La Sante Et De La Recherche Medicale) ACTIVATING AGENTS OF THE DIFFERENTIATION CLUSTER 47 FOR USE IN THE TREATMENT OF INFLAMMATION
US20210052543A1 (en) 2018-01-09 2021-02-25 Brigham Young University Compositions and Methods for Treating Pain with Wogonin
WO2022113887A1 (ja) * 2020-11-27 2022-06-02 京都府公立大学法人 炎症性網膜疾患の判定方法、炎症性網膜疾患治療剤、及び炎症性網膜疾患治療剤のスクリーニング方法
WO2022232001A1 (en) * 2021-04-26 2022-11-03 President And Fellows Of Harvard College Cd47 compositions and methods for the treatment of degenerative ocular diseases
CN116831988A (zh) * 2023-06-13 2023-10-03 南京鼓楼医院 一种载肽模拟物pkhb1的脂质体眼用制剂及其制备方法

Citations (6)

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Publication number Priority date Publication date Assignee Title
JP2012531893A (ja) 2009-06-29 2012-12-13 ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム アルギナーゼ製剤および方法
US20140127269A1 (en) 2012-02-13 2014-05-08 The Schepens Eye Research Institute, Inc. Anti-Inflammatory Peptide Derived From Thrombospondin-1 and Uses Thereof
WO2015100113A2 (en) 2013-12-23 2015-07-02 Memorial Sloan-Kettering Cancer Center Methods and compositions for treating cancer using peptide nucleic acid-based agents
JP2015520178A (ja) 2012-06-06 2015-07-16 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル 癌の処置における使用のための方法及び医薬的組成物
WO2016044383A1 (en) 2014-09-17 2016-03-24 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Anti-cd276 antibodies (b7h3)
WO2016061133A1 (en) 2014-10-14 2016-04-21 Riptide Bioscience, Inc. Peptides having anti-inflammatory properties

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Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
DE3920358A1 (de) 1989-06-22 1991-01-17 Behringwerke Ag Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
EP1136556B1 (en) 1991-11-25 2005-06-08 Enzon, Inc. Method of producing multivalent antigen-binding proteins
US6001962A (en) 1996-11-15 1999-12-14 The Regents Of The University Of California Modified Fas ligands
CA2226962A1 (en) * 1998-02-16 1999-08-16 Marie Sarfati Use of binding agents to cd47 and its ligands in the treatment or the prophylaxis of various inflammatory, autoimmune and allergic diseases and in the treatment of graft rejection
US6846637B1 (en) 1998-06-18 2005-01-25 Imed Ab Fas peptides and antibodies for modulating apoptosis
EP2479284B1 (en) 2006-07-13 2017-09-20 University of Iowa Research Foundation Methods and reagents for treatment and diagnosis of vascular disorders and age-related macular degeneration
CA2747678A1 (en) * 2008-12-19 2010-06-24 Novartis Ag Soluble polypeptides for use in treating autoimmune and inflammatory disorders
WO2011137363A1 (en) 2010-04-30 2011-11-03 Allergan, Inc. Novel treatment for age related macular degeneration and ocular ischemic disease associated with complement activation by targeting 5-lipoxygenase
ES2616010T3 (es) 2010-05-14 2017-06-09 The Board Of Trustees Of The Leland Stanford Junior University Anticuerpos monoclonales humanizados y quiméricos a CD47
US10004780B2 (en) 2012-10-17 2018-06-26 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for the treatment of age-related macular degeneration (AMD)
EP2898896A1 (en) * 2014-01-22 2015-07-29 Université Pierre et Marie Curie (Paris 6) Agents for use in the treatment of retinal inflammation
FR3036620B1 (fr) * 2015-05-27 2017-09-01 Inst Biophytis Utilisation de 3-desoxyanthocyanidines pour le traitement de maladies oculaires
CA3023802C (en) * 2016-05-10 2025-02-04 Inserm (Institut De La Sante Et De La Recherche Medicale) ACTIVATING AGENTS OF THE DIFFERENTIATION CLUSTER 47 FOR USE IN THE TREATMENT OF INFLAMMATION

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012531893A (ja) 2009-06-29 2012-12-13 ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム アルギナーゼ製剤および方法
US20140127269A1 (en) 2012-02-13 2014-05-08 The Schepens Eye Research Institute, Inc. Anti-Inflammatory Peptide Derived From Thrombospondin-1 and Uses Thereof
JP2015520178A (ja) 2012-06-06 2015-07-16 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル 癌の処置における使用のための方法及び医薬的組成物
WO2015100113A2 (en) 2013-12-23 2015-07-02 Memorial Sloan-Kettering Cancer Center Methods and compositions for treating cancer using peptide nucleic acid-based agents
WO2016044383A1 (en) 2014-09-17 2016-03-24 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Anti-cd276 antibodies (b7h3)
WO2016061133A1 (en) 2014-10-14 2016-04-21 Riptide Bioscience, Inc. Peptides having anti-inflammatory properties

Also Published As

Publication number Publication date
US20190225649A1 (en) 2019-07-25
EP3454884B1 (en) 2023-07-12
JP2023179752A (ja) 2023-12-19
JP2019521963A (ja) 2019-08-08
WO2017194586A1 (en) 2017-11-16
EP3454884A1 (en) 2019-03-20
US11142548B2 (en) 2021-10-12
CA3023802C (en) 2025-02-04
CA3023802A1 (en) 2017-11-16
JP2022078244A (ja) 2022-05-24

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