JP7458229B2 - Pest repellent composition - Google Patents

Description

The present invention relates to a water-in-oil or non-aqueous pest repellent composition.

BACKGROUND Pests, such as flying pests such as mosquitoes and flies, transmit pathogens to humans and other animals, causing infectious diseases and dermatitis. In particular, some mosquitoes are extremely harmful insects from a hygienic point of view, as they transmit pathogens such as dengue fever, Zika fever, yellow fever, encephalitis, and malaria.
In recent years, the damage caused by mosquito-borne infectious diseases is increasing due to global warming, urbanization, and the expansion of mosquito habitats due to an increase in the number of tourists. In particular, dengue fever threatens as many as 40% of the world's population, and the World Health Organization (WHO) estimates that the number of infected people worldwide reaches 390 million annually, and the number is still increasing. I'm on my way. Dengue fever is one of the 17 ``Neglected Tropical Diseases (NTDs)'' defined by the WHO, and has become an important social problem in areas with insufficient sanitary infrastructure, such as in emerging countries.

Conventionally, methods of protecting oneself from such flying pests have been widely used, such as spraying insecticides or applying repellents to the skin surface, with DEET (N,N-diethyltoluamide) being a typical repellent.

Pests such as mosquitoes possess chemical receptor systems such as thermoreceptors that detect animal body temperature, olfactory receptors that detect volatile substances such as body odor, and carbon dioxide receptors that detect carbon dioxide. DEET repels pests by modulating their chemoreceptive systems and neutralizing their cognitive senses. However, DEET has an unpleasant odor and requires a certain amount or more to exhibit a sufficient repellent effect. Furthermore, it is known to cause allergies and rough skin in some people, and there is a problem in that the amount and number of times it can be used is limited for young children and people with sensitive skin.

Therefore, the use of natural essential oils as repellent ingredients is being considered. Natural essential oils such as citronella oil, lemon eucalyptus oil, lemongrass oil, orange oil, and cassia oil are also used in candles and aroma lotions, and are highly safe for the human body. However, the repellent effect against these pests is not sufficient, and there are problems with its practicality.

In addition, various proposals have been made regarding repellents and repellent compositions for pests. For example, Patent Document 1 describes that an insect repellent such as DEET is added to a skin protective agent containing a fluorine/polyether co-modified silicone and an ultraviolet protection component. Patent Document 2 discloses an insect repellent containing caran-3,4-diol and a silicone oil having a viscosity of 5000 cSt or less at 25°C. Further, Patent Document 3 discloses an insect repellent characterized by containing a silicone compound as an active ingredient.

Japanese Patent Application Publication No. 8-59447 Japanese Patent Application Publication No. 8-81307 Japanese Patent Application Publication No. 2006-36759

Among pest repellents, those applied to the skin are not only effective in their initial pest repellent effect, but also have a long-lasting repellent effect, are safe for the human body, and have a good feel when applied to the skin. It is desirable that the system also has the following performance characteristics. However, as mentioned above, currently available major pest repellents do not fully meet these demands.
For example, existing pest repellents such as DEET described in Patent Documents 1 and 2 have unpleasant odors, and are known to cause allergies and rough skin in some people. In addition, some countries have restrictions on the amount used for young children. Under these circumstances, there is a need for repellents that are safer for the human body and can be used with peace of mind by infants and people with sensitive skin.
Furthermore, unlike the insect repellent described in Patent Document 3, a repellent composition of the type applied to human skin has excellent not only initial pest repellent effect but also long-lasting repellent effect, and It is also desired that the product has the properties of being less sticky and providing a good feel when applied.

Furthermore, it is an urgent task to realize the Sustainable Development Goals (SDGs), which were adopted as goals for the international community to achieve by 2030 at the United Nations Summit in September 2015, and to ensure that the environment and society are sustained into the future. Technology and innovation that make this possible are needed. In other words, compositions and methods for repelling pests that are safe for the human body, environmentally friendly, and can be used by anyone with peace of mind are essential technologies needed to achieve the Sustainable Development Goals. For example, out of the 17 goals of the SDGs, Goal 3 "Good health and well-being," Goal 6 "Safe water and sanitation for all," and Goal 13 " It is thought that it can contribute to solving the problem of "concrete measures to combat climate change."

Therefore, the objective of the present invention is to provide a water-in-oil or non-aqueous pest repellent composition that is safe, has a pleasant feel with little stickiness when applied to the skin, and has an excellent and sustained repellent effect against pests, particularly flying pests.

The present inventor has proposed a water-in-oil type or non-aqueous type insect pest that contains a predetermined amount of a non-volatile liquid oil component having a specific surface tension and viscosity, and a hydrophobic particle having a specific volume-median particle size. It has been found that a repellent composition can solve the above problems.
That is, the present invention provides the following [1] to [4].
[1] A water-in-oil or non-aqueous pest repellent composition or pest retention suppressing composition containing the following components (A) and (B).
(A) silicone oil, ester oil, ether oil, hydrocarbon oil, aliphatic alcohol, which has a surface tension of 40 mN/m or less at 25°C and a viscosity of 400 mPa·s or less at 23°C measured by a B-type rotational viscometer; One or more nonvolatile liquid oil components selected from the group consisting of polyhydric alcohols: 50% by mass or more and 99.5% by mass or less (B) Hydrophobic particles with a volume median particle size of 0.1 μm or more and 40 μm or less: 0 .5% by mass or more and 35% by mass or less [2] Water-in-oil type containing the following components (A) and (B), and the content of pest repellents other than component (A) is 15% by mass or less Or a non-aqueous mosquito repellent composition or a mosquito retention suppressing composition.
(A) silicone oil, ester oil, ether oil, hydrocarbon oil, aliphatic alcohol, which has a surface tension of 40 mN/m or less at 25°C and a viscosity of 400 mPa·s or less at 23°C measured by a B-type rotational viscometer; One or more nonvolatile liquid oil components selected from the group consisting of polyhydric alcohols: 50% by mass or more and 99.5% by mass or less (B) One or more types selected from the group consisting of acrylic resins, silicone resins, and polyurethane resins Hydrophobic particles with a volume median particle size of 0.1 μm or more and 40 μm or less, including resin particles composed of resin: Composition of 0.5% by mass or more and 35% by mass or less [3] [1] or [2] A method of repelling pests or mosquitoes by applying something to the surface of a person's skin.
[4] A method for suppressing the retention of pests or mosquitoes, which prevents pests from remaining on human skin by attaching the composition of [1] or [2] to the limbs of the pests.

The present invention can provide a water-in-oil or non-aqueous pest repellent composition, a water-in-oil or non-aqueous pest retention suppression composition, a pest repellent method, and a pest retention suppression method that are safe, have a good feel when applied to the skin, and have an excellent long-lasting repellent effect against pests, particularly flying pests.

[Pest repellent composition, pest retention suppressing composition]
The pest repellent composition and pest retention suppressing composition of the present invention (hereinafter also collectively referred to as "the composition of the present invention") are water-in-oil type compositions containing the following components (A) and (B). Or it is a non-aqueous composition.
(A) silicone oil, ester oil, ether oil, hydrocarbon oil, aliphatic alcohol, which has a surface tension of 40 mN/m or less at 25°C and a viscosity of 400 mPa·s or less at 23°C measured by a B-type rotational viscometer; One or more nonvolatile liquid oil components selected from the group consisting of polyhydric alcohols: 50% by mass or more and 99.5% by mass or less (B) Hydrophobic particles with a volume median particle size of 0.1 μm or more and 40 μm or less: 0 .5 mass% or more and 35 mass% or less

The composition of the present invention contains specific amounts of component (A) and component (B), is safe, has a good feel when applied to the skin, and has an excellent long-lasting effect of repelling pests, especially flying pests. The composition may be aqueous or non-aqueous. In the present invention, the term "non-aqueous composition" means a composition that does not substantially contain water. For example, the content of water in the non-aqueous composition of the present invention is preferably less than 1% by mass, more preferably 0.5% by mass or less, even more preferably 0.1% by mass or less.

In the present invention, "repellent effect against pests" means that even if a pest comes into contact with an object, it does not stay there but immediately leaves, and the composition of the present invention corresponds to a contact repellent composition. That is, the pest repellent effect in the present invention is different from repellents or insect repellents that repel pests without contacting the object, such as those that repel pests from the object or those that prevent pests from approaching the object, and insecticides that have an insecticidal effect against pests and exterminate them. The composition of the present invention has an effect of repelling pests, because even if a pest such as a mosquito lands on an object to which the composition is applied or attached, the pest does not stay there but immediately leaves.
Specifically, the composition has a retention-inhibiting effect of preventing pests such as mosquitoes from remaining in a specific area of the skin surface for a period of time required for their stingers to penetrate, specifically, for one second or more, after landing on the skin of an animal such as a human. Such an effect is based on a novel pest repellent principle, and is safe without side effects such as rough skin. Therefore, the composition of the present invention can be used as a pest retention-inhibiting composition.
In the present invention, the "long-lasting repellent effect against pests" means that the repellent effect continues even after time has passed after the composition of the present invention is applied to an object. In the following description, the long-lasting repellent effect, particularly against flying pests, in the present invention will be simply referred to as the "long-lasting repellent effect."

The composition of the present invention contains, as component (A), one or more non-volatile liquid oily components having a surface tension of 40 mN/m or less at 25° C. and a viscosity of 400 mPa·s or less at 23° C. as measured by a B-type rotational viscometer, selected from the group consisting of (a) silicone oils, (b) ester oils, (c) ether oils, (d) hydrocarbon oils, (e) aliphatic alcohols, and (f) polyhydric alcohols.
The composition of the present invention, which contains component (A), has an excellent and sustained repellent effect against pests, particularly flying pests. The reason for this is not clear, but is thought to be as follows.
The present inventors have found that flying pests such as mosquitoes have the property of avoiding staying on a surface where their legs become wet in order to avoid the attractive force generated from the landing surface when their legs become wet. Since the legs of flying pests such as mosquitoes are hydrophobic, a liquid oily component with a surface tension of 40 mN/m or less at 25°C has a high affinity with the legs of flying pests, and a liquid oily component with a viscosity of 400 mPa·s or less will have a sufficiently large contact area between the legs of the flying pests and the liquid oily component in a short time when the legs of the flying pests come into contact with the liquid oily component. Therefore, when a flying pest lands on a surface to which component (A) is applied or attached, the legs become wet, and it is considered that the flying pests avoid the attractive force generated from the landing surface and fly away without staying at the landing point.
In the present invention, landing refers to a flying pest such as a mosquito contacting an object for less than one second, and stationary refers to a flying pest such as a mosquito continuing to contact an object for one second or more.

In addition, the composition of the present invention contains a predetermined amount of component (B) in addition to component (A), so that the repellent effect of component (A) is improved, and water-in-oil or non-aqueous Even if the composition is in the form of a mold, it will feel good when applied to the skin.

<Component (A): Non-volatile Liquid Oily Component>
Component (A) contained in the composition of the present invention is one or more non-volatile liquid oily components selected from the group consisting of (a) silicone oils, (b) ester oils, (c) ether oils, (d) hydrocarbon oils, (e) aliphatic alcohols, and (f) polyhydric alcohols, each of which has a surface tension of 40 mN/m or less at 25° C. and a viscosity of 400 mPa·s or less at 23° C. as measured by a B-type rotational viscometer.

From the viewpoints of facilitating application to the skin and improving the sustained repellent effect, component (A) is preferably liquid at 20°C, more preferably liquid at 15°C, and even more preferably liquid at 10°C.
The term "liquid" in the liquid oily component means a component that is determined to be liquid in the liquid-solid determination test according to the American Society for Testing and Materials standard "ASTM D 4359-90: Standard Test Method for Determining Where a Material is a Liquid or Solid."
From the viewpoint of improving the sustained repellent effect, component (A) is preferably a water-insoluble or slightly water-soluble component, and specifically, the amount of solubility thereof in 100 g of water at 20° C. is preferably 1 g or less, more preferably 0.5 g or less, even more preferably 0.1 g or less, and even more preferably essentially 0 g.

The liquid oily component of component (A) used in the present invention is a non-volatile liquid oily component from the viewpoint of improving the sustained repellent effect.
Here, the non-volatile liquid oily component in the present invention refers to one having a volatilization rate of 50% or less after drying at 25° C. for 60 minutes under 1 atmosphere, and preferably one having a volatilization rate of 50% or less after drying at 25° C. for 120 minutes under 1 atmosphere. The volatilization rate is evaluated according to the German test standard DIN 53249, and specifically, is performed according to the following steps 1 to 4.
1. Measure the weight (P(g)) of a round filter paper with a diameter of 150 mm.
2. Using a pipette, drop 0.3 g of a sample of component (A) onto a round filter paper, and immediately thereafter measure the weight (W ₀ (g)) of the filter paper.
3. In a ventilated environment, measure the weight of the filter paper at 25° C. at 5-minute intervals using a gravimetric measurement accurate to about 0.001 g. The weight of the filter paper measured 60 minutes after the measurement in 2 is defined as W ₆₀ (g).
4. The value calculated using the formula {((W ₀ - P) - (W ₆₀ - P))/(W ₀ - P)} x 100 is the volatility rate (%).
The lower the volatility of the liquid oily component, the longer the liquid oily component will remain when applied to the skin, resulting in a higher repellent effect. When two or more liquid oily components are used, the volatility of the liquid oily component means the volatility of the mixture of two or more liquid oily components. Therefore, as long as the volatility of the mixture is within the above range, liquid oily components having a volatility of more than 50% after drying at 25°C for 60 minutes under 1 atmosphere may be used in combination.

The surface tension of component (A) at 25° C. is preferably 15 mN/m or more, more preferably 17 mN/m or more from the viewpoint of availability, and from the viewpoint of improving the lasting repellent effect and when applied to the skin. From the viewpoint of improving the feel during use, 40 mN/m or less, preferably 30 mN/m or less, more preferably 28 mN/m or less, even more preferably 25 mN/m or less, even more preferably 23 mN/m or less, and even more Preferably it is 21 mN/m or less. Furthermore, even if the surface tension of the compound itself at 25° C. exceeds 40 mN/m, if the surface tension is lowered by mixing it with other liquid oily components, a sustained repellent effect will be exhibited.
The viscosity of component (A) at 23° C. as measured by a B-type rotational viscometer is preferably 1 mPa·s or more from the viewpoint of suppressing volatility and improving the lasting repellent effect, and from the viewpoint of improving the lasting repellent effect and the skin. From the viewpoint of improving the feel when applied to the surface, the pressure is 400 mPa·s or less, preferably 300 mPa·s or less, more preferably 210 mPa·s or less, still more preferably 100 mPa·s or less, even more preferably 60 mPa·s. s or less, more preferably 45 mPa·s or less, even more preferably 30 mPa·s or less. In addition, when two or more types of liquid oily components having different viscosities are used, the viscosity is meant as a mixture of these liquid oily components.
Note that the surface tension and viscosity of component (A) are measured by the methods described in Examples.

(a) Silicone oil The silicone oil is selected from the group consisting of dimethylpolysiloxane, dimethiconol (dimethylpolysiloxane having a hydroxyl group at the end), methylphenylpolysiloxane, and modified silicone from the viewpoint of improving the lasting repellency effect. One or more types are preferred.
Modified silicones include amino-modified silicones (dimethylpolysiloxane having an amino group), polyether-modified silicones, glyceryl-modified silicones, amino derivative silicones, carboxy-modified silicones, fatty acid-modified silicones, alcohol-modified silicones, aliphatic alcohol-modified silicones, and epoxy. Examples include modified silicone, fluorine-modified silicone, and alkyl-modified silicone.

Silicone oils are selected from the group consisting of dimethylpolysiloxane, dimethiconol, methylphenylpolysiloxane, and modified silicone from the viewpoint of improving the long-lasting repellent effect and providing a good feel when applied to the skin. One or more types are preferable, one or more types selected from the group consisting of dimethylpolysiloxane, dimethiconol, and polyether-modified silicone are more preferable, and dimethylpolysiloxane is even more preferable.

Examples of the dimethylpolysiloxane include one or more selected from the group consisting of linear dimethylpolysiloxane and cyclic dimethylpolysiloxane. Among these, linear dimethylpolysiloxane is more preferred from the viewpoint of improving the lasting repellency effect.
Examples of commercially available linear dimethylpolysiloxanes used as component (A) include Shin-Etsu Chemical Co., Ltd.'s "KF-96" series (KF-96A-5cs, KF-96A-6cs, 10cs, 20cs, 30cs, 50cs, 100cs, 200cs, 300cs, 350cs, etc.), Dow Toray Industries, Inc.'s "DOWSIL SH200C Fluid" series and "DOWSIL 2-1184 Fluid", "Element14 PDMS 5-JC", "Element14 P" DMS 10-JC ”, “Element14 PDMS 20-JC”, etc.

(b) Ester Oil As the ester oil, from the viewpoint of improving the repellent effect, an ester oil represented by any one of the following general formulas (1) to (3) and a dialkyl carbonate compound represented by the following general formula (4) are preferred.

R ¹ -COO-R ² (1)
In general formula (1), R ¹ may be substituted with a hydroxyl group, and is a linear or branched alkyl group having 7 to 23 carbon atoms, or an aromatic hydrocarbon group having 6 to 24 carbon atoms. and R ² represents a linear or branched alkyl group or alkenyl group having 1 to 22 carbon atoms.
When R ¹ is an alkyl group, the number of carbon atoms is preferably 7 or more, more preferably 9 or more, from the viewpoint of improving the lasting repellent effect, and from the viewpoint of improving the feel when applied to the skin, Preferably it is 21 or less, more preferably 17 or less. In addition, when R ¹ is an aromatic hydrocarbon group, the number of carbon atoms is preferably 8 or more, more preferably 10 or more, and has a good feel when applied to the skin, from the viewpoint of improving the lasting repellent effect. From the viewpoint of achieving this, it is preferably 22 or less, more preferably 20 or less.
^R2 is preferably a linear or branched alkyl group or alkenyl group having 20 or less carbon atoms, more preferably 18 or less carbon atoms, from the viewpoint of providing a good feel when applied to the skin.
Furthermore, from the viewpoint of providing a good feel when applied to the skin, it is preferable that at least one of R ¹ and R ² is a branched alkyl group.

Examples of the ester oil represented by the general formula (1) include myristyl 2-ethylhexanoate, cetyl 2-ethylhexanoate, stearyl 2-ethylhexanoate, isodecyl octoate, isocetyl octoate, isononyl isononanoate, and isotridecyl isononanoate. , cetearyl isononanoate, octyl propylheptanoate, methyl laurate, isopropyl myristate, octyldodecyl myristate, isopropyl palmitate, 2-ethylhexyl palmitate, isocetyl palmitate, 2-ethylhexyl stearate, isocetyl stearate, stearic acid Isotridecyl, isopropyl isostearate, octyl isostearate, isocetyl isostearate, isostearyl isostearate, 2-ethylhexyl hydroxystearate, methyl oleate, oleyl oleate, isobutyl oleate, oleyl erucate, alkyl benzoate (number of carbon atoms in alkyl) 12 to 15), and diethylhexyl naphthalene dicarboxylate.

( ^R3O ) _-CH2CH ( ^OR4 ) _-CH2 ( ^OR5 ) (2)
In formula (2), R ³ , R ⁴ and R ⁵ each independently represent a hydrogen atom or a group represented by the following formula (2-1), provided that all of them are not hydrogen atoms.
-CO-R ⁶ (2-1)
(In the formula, ^R6 represents an alkyl or alkenyl group having 7 to 23 carbon atoms, preferably 17 or less, which may be substituted with a hydroxyl group.)
The ester oil represented by the general formula (2) may be one or more selected from the group consisting of glyceryl tri-2-ethylhexanoate and glyceryl tricaprylate. These may also be plant-derived ester oils such as jojoba oil, olive oil, sunflower oil, soybean oil, peanut oil, rapeseed oil, almond oil, palm oil, coconut oil, castor oil, wheat germ oil, grape seed oil, thistle oil, evening primrose oil, macadamia nut oil, corn germ oil, and avocado oil.

R ⁷ O-(AO)m-COR ⁸ (3)
In the general formula (3), R ⁷ represents an aromatic hydrocarbon group having 6 to 20 carbon atoms, and R ⁸ represents an alkyl group or alkenyl group having 1 to 23 carbon atoms. AO represents an alkyleneoxy group having 2 or more and 4 or less carbon atoms, and m represents the average number of added moles of 1 or more and 50 or less.
^R7 preferably has 6 or more carbon atoms from the viewpoint of improving the lasting repellent effect, and preferably 12 or less, more preferably 10 or less from the viewpoint of improving the feel when applied to the skin. is an aromatic hydrocarbon group, more preferably a benzyl group.
R ⁸ preferably has 7 or more carbon atoms, more preferably 11 or more carbon atoms, from the viewpoint of improving the lasting repellent effect, and preferably 21 or less from the viewpoint of giving a good feel when applied to the skin. , more preferably an alkyl group of 15 or less.
The AO group is preferably a propyleneoxy group from the viewpoint of improving the lasting repellent effect, and m is preferably 1 from the viewpoint of improving the lasting repellent effect and providing a good feel when applied to the skin. The number is 1 or more and 10 or less, more preferably 1 or more and 5 or less.
Examples of the ester oil represented by the general formula (3) include an ester of a 3-mol adduct of benzyl alcohol with propylene oxide and myristic acid (Croda Mol STS), a 3-mol adduct of propylene oxide with benzyl alcohol and 2-ethyl One or more types selected from the group consisting of hexanoic acid esters (Croda Mol SFX) can be mentioned.

R ⁹ -O-(CH ₂ CH ₂ O)v-CO-(OCH ₂ CH ₂ )w-OR ¹⁰ (4)
In the general formula (4), R ⁹ and R ¹⁰ each independently represent an alkyl group or alkenyl group having 6 to 22 carbon atoms, and v and w each independently represent 0 or an average of 1 to 50. Indicates the number of moles added.
R ⁹ and R ¹⁰ preferably have 8 or more carbon atoms from the viewpoint of improving the lasting repellent effect, and preferably 18 or less, more preferably from the viewpoint of improving the feel when applied to the skin. It is an alkyl group of 12 or less.
v and w are preferably 0 or a number from 1 to 5, more preferably 0, from the viewpoint of providing a good feel when applied to the skin.
Examples of the dialkyl carbonate compound represented by the general formula (4) include dioctyl carbonate ("Cetiol CC" by Cognis) and the like.

Examples of ester oils other than those mentioned above include esters of polyhydric carboxylic acids and alcohols, and esters of polyhydric alcohols other than glycerin and fatty acids. Specific examples include the group consisting of diisopropyl dimerate, diisopropyl adipate, diethoxyethyl succinate, 2-ethylhexyl succinate, propanediol dicaprate, neopentyl glycol dicaprate, neopentyl glycol di-2-ethylhexanoate, etc. One or more types selected from: Among these, esters of neopentyl glycol and fatty acids are preferred from the viewpoint of improving the sustained repellency effect, and one or more esters selected from the group consisting of neopentyl glycol dicaprate and neopentyl glycol di-2-ethylhexanoate are preferred. More preferred. Among the above ester oils (b), one or more selected from the group consisting of ester oils represented by general formula (1) and esters of neopentyl glycol and fatty acids are preferred.

(c) Ether oil From the viewpoint of improving the sustained repellency effect, the ether oil may be a dialkyl ether compound represented by the following general formula (5) or a polyoxyalkylene alkyl ether compound represented by the following general formula (6). is preferred.

R ¹¹ -O-R ¹² (5)
In the general formula (5), R ¹¹ and R ¹² are each independently a linear or branched alkyl group or alkenyl group having 6 to 22 carbon atoms, or an aromatic hydrocarbon group having 6 to 24 carbon atoms. shows. R ¹¹ and R ¹² are preferably alkyl groups from the viewpoint of improving the lasting effect of repelling, and the number of carbon atoms thereof is preferably 8 or more from the viewpoint of improving the lasting effect of repelling. From the viewpoint of improving the feel of the product, it is preferably 18 or less, more preferably 16 or less, and still more preferably 12 or less.
Examples of dialkyl ether compounds represented by the general formula (5) include dihexyl ether, dioctyl ether (Cognis Co., Ltd. "Cetiol OE"), dicaprylyl ether, cetyl-1,3-dimethylbutyl ether (Kao Corporation "ASE-166K"). ”), etc.

R ¹³ -O-(PO)r(EO)s-H (6)
In the general formula (6), R ¹³ represents an alkyl group or alkenyl group having 6 to 22 carbon atoms, PO represents a propyleneoxy group, and EO represents an ethyleneoxy group. r represents an average number of added moles of 0.1 or more and 15 or less, and s represents an average number of added moles of 0 or more and 10 or less. If s is not 0, the addition format of PO and EO may be random or block.
The number of carbon atoms in R ¹³ is preferably 8 or more from the viewpoint of improving the lasting repellent effect, and preferably 20 or less, more preferably 18 or less from the viewpoint of improving the feel when applied to the skin. , more preferably 12 or less.
The average number of added moles r is preferably 1 or more, more preferably 2 or more, and even more preferably 3 or more from the viewpoint of improving the repellent lasting effect, and from the viewpoint of giving a good feel when applied to the skin. , preferably 13 or less, more preferably 10 or less.
The average number of added moles s is preferably 5 or less, more preferably 1 or less, and even more preferably 0 from the viewpoint of providing a good feel when applied to the skin.
Examples of the polyoxyalkylene alkyl ether compound represented by the general formula (6) include polypropylene glycol, polyoxypropylene octyl ether, polyoxypropylene decyl ether, in which the average number of added moles r of propyleneoxy groups is 3 or more and 10 or less, and polyoxypropylene lauryl ether are preferred.
Among the above-mentioned ether oils (c), ether oils represented by general formula (5) are preferred from the viewpoint of improving the lasting repellent effect.

(d) Hydrocarbon oil Hydrocarbon oils include liquid paraffin, liquid isoparaffin, squalane, squalene, isohexadecane, isoeicosane, hydrogenated polyisobutene, light liquid isoparaffin, heavy liquid isoparaffin, α-olefin oligomer, and cycloparaffin. Can be mentioned. Among these, one or more selected from the group consisting of liquid paraffin, liquid isoparaffin, squalane, and squalene are preferred from the viewpoint of improving the lasting repellent effect and providing a good feel when applied to the skin. , squalane is more preferred.

(e) Aliphatic Alcohol Examples of the aliphatic alcohol include monovalent chain or cyclic aliphatic alcohols, and monovalent chain aliphatic alcohols are preferred from the viewpoint of improving the lasting repellency effect. The number of carbon atoms in the aliphatic alcohol is preferably 14 or more, more preferably 18 or more, from the viewpoint of improving the lasting repellency effect, and preferably from the viewpoint of giving a good feel when applied to the skin. It is 28 or less, more preferably 24 or less, even more preferably 22 or less.
The aliphatic alcohol may be either straight chain or branched chain, and may be saturated or unsaturated, but from the viewpoint of improving the lasting repellent effect and providing a good feel when applied to the skin. From the viewpoint of the desired effect, branched aliphatic saturated alcohols are preferred.
Examples of straight-chain aliphatic alcohols include oleyl alcohol, and examples of branched-chain aliphatic saturated alcohols include butyl octanol, butyl decanol, hexyl decanol, octyl dodecanol, and the like. Among these, branched-chain aliphatic saturated alcohols are preferred from the viewpoint of improving the lasting repellent effect and providing a good feel when applied to the skin, and are selected from the group consisting of hexyldecanol and octyldodecanol. One or more types are preferred.

(f) Polyhydric alcohol Polyhydric alcohols include aliphatic alcohols with 2 or more carbon atoms, aromatic alcohols, sugar alcohols with 4 or more carbon atoms, and may be either saturated or unsaturated. From the viewpoint of providing a good feel when applied to the skin, one or more selected from the group consisting of aliphatic alcohols having 2 to 10 carbon atoms, aromatic alcohols, and sugar alcohols having 4 to 10 carbon atoms. preferable.
Among polyhydric alcohols, aliphatic alcohols having 2 or more carbon atoms include ethylene glycol, propylene glycol, 1,2-butylene glycol, 1,3-butylene glycol, 1,2-pentanediol, and 1,2-hexanediol. , dihydric alcohols such as diethylene glycol, dipropylene glycol, and hexylene glycol.
Further, examples of the sugar alcohol include sorbitol, erythritol, pentaerythritol, xylitol, mannitol, and the like.

Among the above-mentioned liquid oil components, from the viewpoint of improving the sustained repellency effect, one selected from the group consisting of (a) silicone oil, (b) ester oil, (c) ether oil, and (d) hydrocarbon oil. (a) silicone oil, (b) ester oil, and (d) hydrocarbon oil, more preferably one or more selected from the group consisting of (a) silicone oil, (b) ester oil, and (d) hydrocarbon oil. More preferably, one or more selected from the group consisting of (a) silicone oil is even more preferable.
(a) Among the silicone oils, from the viewpoint of improving the lasting repellency effect, one or more selected from the group consisting of dimethylpolysiloxane, dimethiconol, methylphenylpolysiloxane, and modified silicone is preferred, and more preferably dimethylpolysiloxane. It is one or more selected from the group consisting of siloxane, dimethiconol, and polyether-modified silicone, more preferably dimethylpolysiloxane, and even more preferably linear dimethylpolysiloxane.

(Content of component (A))
The content of component (A) in the composition of the present invention is 50% by mass or more, preferably 55% by mass or more, more preferably 60% by mass or more, and Preferably it is 65% by mass or more. In addition, from the viewpoint of providing a good feel when applied to the skin and ensuring the storage stability of the composition, the content is 99.5% by mass or less, preferably 96.5% by mass or less, and more Preferably it is 95% by mass or less, more preferably 90% by mass or less, still more preferably 80% by mass or less, even more preferably 75% by mass or less. The content of component (A) in the composition of the present invention is 50 to 99.5% by mass, preferably 50 to 96.5% by mass, and more preferably 50 to 95% by mass. , more preferably 55 to 90% by weight, even more preferably 60 to 80% by weight, even more preferably 65 to 75% by weight.

<Component (B): Hydrophobic particles>
The composition of the present invention contains hydrophobic particles having a volume median particle size of 0.1 μm or more and 40 μm or less as component (B). By containing component (B), the composition of the present invention improves the sustained repellency effect of component (A), and provides a pleasant feel when applied to the skin.

In the present invention, the term "hydrophobic particles" refers to particles whose surface wetting tension at 23° C. is 70 mN/m or less. Furthermore, the term "hydrophilic particles" refers to particles whose wetting tension on the surface of the particles is more than 70 mN/m.
When the particles of component (B) are hydrophobic particles having a specific particle size, a sustained repellent effect is improved and a composition that feels good when applied to the skin can be obtained. The component (B) used in the composition of the present invention preferably has a wetting tension of 60 mN/m or less at 23°C from the viewpoint of improving the lasting repellent effect and providing a good feel when applied to the skin. , more preferably 50 mN/m or less. The wetting tension on the particle surface can be measured by the method described in Examples.

The hydrophobic particles of component (B) may be any of organic particles, inorganic particles, and mixtures thereof as long as they exhibit the above-mentioned hydrophobicity, and those commonly used in cosmetics can be used. Among these, component (B) contains hydrophobic organic particles from the viewpoint of improving the lasting repellent effect, improving the feel when applied to the skin, and ensuring the storage stability of the composition. It is preferable to include.

Examples of the resin constituting the hydrophobic organic particles include acrylic resin, silicone resin, polystyrene resin, polyamide resin, polyester resin, polyolefin resin, polystyrene resin, polyurethane resin, vinyl resin, urea resin, phenol resin, fluororesin, and melamine. Examples include resins composed of resins, epoxy resins, polycarbonate resins, acrylic-silicone copolymer resins, acrylic-styrene copolymer resins, cellulose, and the like. These hydrophobic organic particles may be non-crosslinked resin particles or crosslinked resin particles. Alternatively, the particles may be resin particles made of the above-mentioned resin, the surfaces of which have been subjected to hydrophobization treatment.
Among the above, hydrophobic organic particles are selected from the group consisting of acrylic resin, silicone resin, polyurethane resin, and cellulose, from the viewpoint of improving the lasting repellent effect and providing a good feel when applied to the skin. Preferably, resin particles are made of one or more resins selected from the group consisting of acrylic resins, silicone resins, and polyurethane resins, more preferably resin particles are made of one or more resins selected from the group consisting of acrylic resins, silicone resins, and polyurethane resins. More preferred are resin particles made of one or more resins selected from the group consisting of silicone resins.

The acrylic resin constituting the hydrophobic organic particles includes a homopolymer or copolymer of an acrylic monomer. The acrylic monomer includes (meth)acrylic acid and (meth)acrylic acid ester. "(Meth)acrylic acid" refers to both acrylic acid and methacrylic acid.
Among the (meth)acrylic acid esters, from the viewpoint of providing a good feel when applied to the skin, (meth)acrylic acid alkyl esters are preferred, and the number of carbon atoms in the alkyl group is preferably 1 or more and 18 or less, more preferably 1 or more and 16 or less.
Specific examples of the (meth)acrylic acid alkyl ester include methyl (meth)acrylate, ethyl (meth)acrylate, n-butyl (meth)acrylate, isobutyl (meth)acrylate, sec-butyl (meth)acrylate, tert-butyl (meth)acrylate, 2-ethylhexyl (meth)acrylate, isodecyl (meth)acrylate, lauryl (meth)acrylate, and hexadecyl (meth)acrylate, and these can be used alone or in combination.

In addition to the (meth)acrylic acid and (meth)acrylic acid alkyl ester, the acrylic resin may include polyfunctional resins such as ethylene glycol di(meth)acrylate, propylene glycol di(meth)acrylate, and hexanediol di(meth)acrylate. A crosslinked acrylic resin obtained by further copolymerizing (meth)acrylate may also be used.
Specifically, the acrylic resin includes non-crosslinked acrylic resins such as polymethyl methacrylate, acrylic acid/methyl acrylate copolymer, and butyl acrylate/ethylene glycol dimethacrylate/sodium methacrylate copolymer. Examples include crosslinked acrylic resins such as lauryl methacrylate/ethylene glycol dimethacrylate/sodium methacrylate copolymer (hereinafter sometimes referred to as "(lauryl methacrylate/Na methacrylate) crosspolymer").

Among the hydrophobic organic particles, acrylic resin particles made of one or more acrylic resins selected from the group consisting of polymethyl methacrylate and (lauryl methacrylate/sodium methacrylate) crosspolymers are preferred from the viewpoint of providing a good feel when applied to the skin. Commercially available acrylic resin particles include the particles described in JP-A-2006-225311 as "crosslinked (meth)acrylic acid ester resin powder" and the Ganz Pearl series from Aica Kogyo Co., Ltd.

Examples of the silicone resin constituting the hydrophobic organic particles include organopolysiloxanes such as methylpolysiloxane and methylphenylpolysiloxane; polyorganosilsesquioxanes such as polymethylsilsesquioxane; and composite materials thereof; Copolymers containing polysiloxane chains; and the like. Among these, one selected from the group consisting of methylpolysiloxane, polymethylsilsesquioxane, and composite materials thereof, from the viewpoint of improving the lasting repellent effect and providing a good feel when applied to the skin. More than one species is preferred.
Further, a crosslinked silicone resin obtained by crosslinking the above silicone resin with divinyldimethylpolysiloxane (vinyl dimethicone), phenylvinyldimethylpolysiloxane (phenylvinyl dimethicone), etc. can also be used. Examples of the crosslinked silicone resin include (dimethicone/vinyl dimethicone) cross polymer, (vinyl dimethicone/methicone silsesquioxane) cross polymer, (dimethicone/phenyl vinyl dimethicone) cross polymer, and the like.
Among the hydrophobic organic particles, the silicone resin particles are preferably cross-linked silicone resin particles from the viewpoint of providing a good feel when applied to the skin, and include (dimethicone/vinyl dimethicone) crosspolymer and (vinyl dimethicone/methicone) cross-polymer. More preferred are particles made of one or more silicone resins selected from the group consisting of silsesquioxane (silsesquioxane) crosspolymers. Commercial products of silicone resin particles include Shin-Etsu Chemical Co., Ltd.'s "KSP" series, "KMP" series, "KSG-16" and "Silicone X-52-1621".

As hydrophobic inorganic particles, from the viewpoint of improving the sustained repellent effect and improving the feel when applied to the skin, preferred are inorganic particles whose surfaces have been hydrophobized, such as silica, alumina, talc, kaolin, clay, bentonite, mica, zirconium oxide, magnesium oxide, titanium oxide, zinc oxide, calcium sulfate, barium sulfate, magnesium sulfate, calcium carbonate, and magnesium carbonate. Among these, silica particles whose surfaces have been hydrophobized are preferred from the viewpoint of improving the sustained repellent effect, improving the feel when applied to the skin, and ensuring the storage stability of the composition.

As the hydrophobic treatment, conventionally known surface treatments, such as fluorine compound treatment (perfluoroalkyl phosphate treatment, perfluoroalkyl silane treatment, perfluoropolyether treatment, fluorosilicone treatment, fluorinated silicone resin treatment) are preferable. ), silicone treatment (methylhydrogenpolysiloxane treatment, dimethylpolysiloxane treatment, trimethylsiloxysilicic acid treatment, vapor phase tetramethyltetrahydrogencyclotetrasiloxane treatment is preferred), pendant treatment (alkyl chain treatment after vapor phase silicone treatment) etc.), silane coupling agent treatment, titanium coupling agent treatment, silane treatment (alkylsilane treatment and alkylsilazane treatment are preferred), oil treatment, N-acylated lysine treatment, metal soap treatment (stearate treatment (preferably myristate treatment), acrylic resin treatment, metal oxide treatment, etc., and a combination of two or more of these treatments can also be used.
Among the above, the hydrophobization treatment is preferably one or more selected from the group consisting of silicone treatment and silane treatment, more preferably silane treatment, and even more preferably alkylsilane treatment.

The shape of the hydrophobic particles of component (B) is not particularly limited, and examples thereof include spherical, plate-like, columnar, and acicular shapes. Among these, spherical particles are preferred from the viewpoint of improving the lasting repellent effect and providing a good feel when applied to the skin. Further, particles having irregularities on the surface or porous particles may be used.

From the viewpoint of improving the repellent duration effect, the hydrophobic particles of component (B) have a volume median particle size (D50) of 0.1 μm or more, preferably 0.5 μm or more, and more preferably 1.0 μm or more, and from the viewpoint of improving the repellent duration effect and from the viewpoint of providing a good feel when applied to the skin, the volume median particle size is 40 μm or less, preferably 30 μm or less, and more preferably 15 μm or less. The volume median particle size of component (B) is 0.1 to 40 μm, preferably 0.5 to 30 μm, and more preferably 1.0 to 15 μm.
In the present invention, the volume median particle size (D50) means the particle size at which the cumulative volume frequency calculated as a volume fraction is 50%, calculated from the smallest particle size.

When two or more types of particles are used as component (B), the volume median particle size of component (B) means the volume median particle size of a mixture of all particles. Specifically, after determining the volume median particle diameter (Pi _D50 ) of each particle group, the value is calculated based on the following formula (a).

Pi _D50 : Volume median particle diameter (D50) (μm) of the particle group Pi constituting the particle
Xi: Content ratio (%) of particle group Pi constituting particles
ρi: Density of particle group Pi constituting the particle (g/cm ³ )
For example, the density of resin particles is 1.18 g/cm ³ and the density of silica is 2.20 g/cm ³ . Further, Pi _D50 can be measured using a light scattering particle size distribution measuring device, and specifically can be measured by the method described in Examples.

In the present invention, the component (B) is measured using a light scattering particle size distribution measuring device, from the viewpoint of improving the repellent lasting effect and giving a good feel when applied to the skin. In the particle size distribution curve, the volume ratio of particles with a diameter of 45 μm or more to the total volume of the particles is preferably 15% or less, more preferably 10% or less.
By containing particles having such a particle size distribution, the composition of the present invention imparts structural viscosity to the composition, giving it a good feel when applied to the skin and improving the duration of repellency. becomes possible. Specifically, the particle size distribution of component (B) can be measured by the method described in the Examples.

(Content of component (B))
The content of component (B) in the composition of the present invention is 0.5% by mass or more, preferably 2% by mass or more, more preferably 4% by mass or more, even more preferably 6% by mass or more, and even more preferably 10% by mass or more, from the viewpoint of improving the repellent duration effect and ensuring a good feel when applied to the skin. The content of component (B) in the composition of the present invention is 35% by mass or less, preferably 30% by mass or less, more preferably 25% by mass or less, and even more preferably 20% by mass or less, from the viewpoint of improving the repellent duration effect and ensuring the storage stability of the composition. The content of component (B) in the composition of the present invention is 0.5 to 35% by mass, preferably 2 to 30% by mass, more preferably 4 to 25% by mass, even more preferably 6 to 20% by mass, and even more preferably 10 to 20% by mass.

In the composition of the present invention, the mass ratio [(A)/(B)] between component (A) and component (B) is determined from the viewpoint of improving the lasting repellent effect and providing a good feel when applied to the skin. From the viewpoint of achieving this, it is preferably 1 or more, more preferably 2 or more, even more preferably 4 or more, and from the same viewpoint, it is preferably 30 or less, more preferably 15 or less, and still more preferably 8 or less. In the composition of the present invention, the mass ratio [(A)/(B)] between component (A) and component (B) is preferably 1 or more and 30 or less, more preferably 2 or more and 15 or less. Yes, and more preferably 4 or more and 8 or less.

The composition of the present invention is a water-in-oil type composition from the viewpoint of improving the lasting repellent effect, improving the feel when applied to the skin, and improving the storage stability of the composition. It is preferable to do so.
In addition, in the case of a water-in-oil type composition, the water content in the composition is determined from the viewpoint of providing a good feel when applied to the skin, and from the viewpoint of stabilizing the water-in-oil type composition. From the viewpoint of formation, the content is preferably 3% by mass or more, more preferably 6% by mass or more, still more preferably 10% by mass or more, even more preferably 12% by mass or more. Further, from the viewpoint of improving the sustained repellency effect, the content is preferably less than 30% by mass, more preferably 25% by mass or less, more preferably 21% by mass or less, even more preferably 18% by mass or less. The content of water in the composition of the present invention is preferably 3% by mass or more and less than 30% by mass, more preferably 6 to 25% by mass, even more preferably 10 to 21% by mass, even more preferably It is 12 to 18% by mass.

In addition, when the composition of the present invention is a water-in-oil composition, the mass ratio of component (A) and water [component (A)/water] is determined from the viewpoint of improving the lasting repellent effect and when applied to the skin. From the viewpoint of improving the feel when touched, it is preferably 1 or more, more preferably 3 or more, even more preferably 3.2 or more, even more preferably 4 or more, and from the same viewpoint, preferably 8 or less, More preferably it is 7 or less, still more preferably 6.5 or less, even more preferably 6 or less. In the composition of the present invention, the mass ratio of component (A) to water [component (A)/water] is preferably 1 or more and 8 or less, more preferably 3 or more and 7 or less, and even more preferably 3.2. 6.5 or less, more preferably 4 or more and 6 or less.

(surfactant)
The composition of the present invention may further contain a surfactant. When the composition of the present invention is a water-in-oil composition, the viewpoints of ensuring excellent applicability to the skin by dispersing or dissolving each component well, and emulsion stability of the water-in-oil composition It is preferable to contain a surfactant from the viewpoint of improving the composition and ensuring the storage stability of the composition.
The surfactant preferably has a suitable emulsifying ability, and when the composition of the present invention is a water-in-oil composition, it is particularly preferable to contain a nonionic surfactant with an HLB of 8 or less.
Here, HLB (Hydrophilic-Lipophilic Balance) indicates the molecular weight of the hydrophilic group portion in the total molecular weight of the surfactant, and is determined by the Griffin formula. be. From the viewpoint of emulsifying ability, the HLB of the nonionic surfactant is more preferably 6 or less, still more preferably 5.5 or less, and preferably 3 or more.

Nonionic surfactants with an HLB of 8 or less include polyoxyethylene glycerin fatty acid esters such as polyoxyethylene glyceryl triisostearate and polyoxyethylene glyceryl trioleate; polyglycerin fatty acids such as tetraglyceryl monostearate and tetraglyceryl monooleate; Esters; Sorbitan fatty acid esters such as sorbitan palmitate, sorbitan sesquioleate, and sorbitan sesquiisostearate; polyoxyethylene hydrogenated castor oil; propylene glycol fatty acid esters such as propylene glycol monostearate; polyoxyethylene oleyl ether, polyoxyethylene cetyl ether , polyoxyethylene alkyl ethers such as polyoxyethylene behenyl ether and polyoxyethylene stearyl ether; polyoxyethylene polyoxypropylene alkyl ethers such as polyoxyethylene-polyoxypropylene-decyl ether; alkyl alkanolamides; fatty acid alkanolamides; Examples include oxyethylene alkylamine; polyether-modified silicone; glycerin-modified silicone. Among these, polyether-modified silicones are preferred from the viewpoint of improving the emulsion stability of the water-in-oil composition.

The silicone chain of the polyether-modified silicone may be either linear or branched. For example, linear polyoxyethylene/methylpolysiloxane copolymer, linear poly(oxyethylene/oxypropylene)methylpolysiloxane copolymer, etc. Polymers, silicone chain branched polyoxyethylene methyl polysiloxane copolymers, alkyl chain/silicone chain branched polyoxyethylene methyl polysiloxane copolymers, and the like. The linear polyoxyethylene/methylpolysiloxane copolymer and the linear poly(oxyethylene/oxypropylene)methylpolysiloxane copolymer may be further modified with alkyl or the like. Among these, from the viewpoint of improving emulsion stability in water-in-oil compositions, linear polyoxyethylene/methylpolysiloxane copolymers and linear poly(oxyethylene/oxypropylene) methylpolysiloxane copolymers are used. One or more types selected from the group consisting of coalescence and modified products thereof are preferred.

Commercially available linear polyoxyethylene/methylpolysiloxane copolymers or modified products thereof include Shin-Etsu Chemical Co., Ltd.'s "KF-6015" (PEG-3 dimethicone, HLB4.5) and "KF-6016". ” (PEG-9 methyl ether dimethicone, HLB 4.5), “KF-6017” (PEG-10 dimethicone, HLB 4.5), “DOWSIL SH 3773 M” (PEG-12 dimethicone, HLB 8) from Dow Toray Industries, Inc. 0), "DOWSIL SH 3775 M Fluid" (PEG-12 dimethicone, HLB5.0), and the like.

When a surfactant is used in the composition of the present invention, its content is determined from the viewpoints of ensuring excellent applicability to the skin by dispersing or dissolving each component well, and emulsion stability of the water-in-oil composition. From the viewpoint of improving the storage stability of the composition and ensuring the storage stability of the composition, preferably 0.01% by mass or more, more preferably 0.05% by mass or more, and even more preferably 0.1% by mass or more in the composition. From the same point of view, it is preferably 10% by mass or less, more preferably 7% by mass or less, even more preferably 5% by mass or less.

(volatile oil)
When the composition of the present invention is made into a non-aqueous composition, it is preferable that the composition further contains a volatile oil from the viewpoint of providing a good feel when applied to the skin. In the present invention, volatile oil refers to an oil whose volatilization rate after drying at 25° C. for 60 minutes at 1 atmosphere, as measured by the method described above, is more than 50%.
The volatile oil may be used without any particular restriction as long as it is a liquid oil component with a volatility rate of over 50% as defined above, but from the viewpoint of ensuring the storage stability of the composition, isododecane, hexamethyldisiloxane, deca One or more selected from the group consisting of methylcyclopentasiloxane, methyltrimethicone, and dimethylpolysiloxane having a kinematic viscosity of 2 cSt or less at 25° C. is preferred. Note that the kinematic viscosity can be measured using an Ubbelohde viscometer.

When a volatile oil is used in the composition of the present invention, its content is preferably 1% by mass or more, more preferably 5% by mass in the composition, from the viewpoint of providing a good feel when applied to the skin. Above, more preferably 10% by mass or more, and from the same point of view, preferably 40% by mass or less, more preferably 30% by mass or less, still more preferably 25% by mass or less, even more preferably 20% by mass or less. .

<Other ingredients>
The composition of the present invention may contain ingredients other than those mentioned above, such as preservatives, colorants, humectants, fragrances, pH adjusters, vitamins, blood circulation promoters, active oxygen scavengers, etc., to the extent that the effects of the invention are not impaired. It can also contain medicinal ingredients and physiologically active ingredients such as anti-inflammatory agents, whitening agents, and bactericidal agents. Each of these components can also be used for other purposes, such as fragrances and disinfectants.

The composition of the present invention preferably contains component (A) as an active repellent ingredient for pest repellency, and does not contain any other effective amount of pest repellent, from the viewpoint of preventing allergies and rough skin in the user, and may be substantially free of pest repellent other than component (A).
The composition of the present invention has a sustained repellent effect even if it does not contain an effective amount of an existing pest repellent described later. In other words, even if the composition of the present invention contains a pest repellent other than component (A) in an amount less than the lower limit of the effective amount, as long as the retention-inhibiting effect of preventing pests from remaining in place even if they land is exhibited, the retention-inhibiting effect of the present invention is exhibited.

Here, "not containing an effective amount of pest repellents other than component (A)" generally means that the content of existing pest repellents other than component (A) in the composition of the present invention is Preferably 15% by mass or less, more preferably 10% by mass or less, still more preferably 5% by mass or less, even more preferably 4% by mass or less, even more preferably 3% by mass or less, even more preferably 1% by mass or less. It means something. For the effective amount of existing pest repellents, reference may be made to, for example, the minimum effective amount published by manufacturers of each repellent product. More specifically, the effective amount of DEET:N,N-diethyltoluamide, which is an existing pest repellent described below, is 4% by mass or more, preferably 10% by mass or more, and icaridin:1-methylpropyl- The effective amount of 2-(2-hydroxyethyl)-1-piperidinecarboxylate is 4% by mass or more, IR3535: The effective amount of 3-(acetylbutyl)aminopropionate ethyl ester is 4% by mass or more, citronella oil. An effective amount is 10% by weight or more.

Further, the effective amount of existing pest repellents can also be measured by the repellency evaluation test described below using mosquitoes as pests.
(Repellent evaluation test)
100 mated female mosquitoes (Aedes albopictus) are placed in a plastic cage (30 x 30 x 30 cm: BugDorm-1 cage) surrounded by mesh. Insert your arm into the Qualatec Super Long Gloves (50cm) (As One Co., Ltd., Catalog number: 3-6432-02) with a rectangular cut 5cm long x 4cm wide on the elbow side about 15cm from the wrist. do. Insert your arm into the cage without applying anything to the exposed area from the cut, and within 2 minutes, the exposed skin must be touched (remained) for at least 1 second after being landed on by a mosquito in 2 places. Check. If the mosquito does not stay for more than 1 second, prepare a new mosquito. Hereinafter, residence of a mosquito for one second or more after landing will be simply expressed as residence.
Testing of the evaluation sample, which is a pest repellent solution, is carried out by adjusting the concentration with ethanol so that the evaluation sample can be applied to the exposed skin area (5 cm x 4 cm) at 2 mg/cm ² .
Using a pipetman, place the solution with adjusted concentration on the exposed area and apply it to the entire exposed area of the skin (required amount of solution: 40-50 μl). After that, let it stand for 3 minutes and start the test. The test is performed by inserting the arm coated with the evaluation sample into a cage for 2 minutes and counting the number of times the arm remains in the cage. The test ends when the test is stopped twice in total, and the test is continued by inserting the arm for 2 minutes every 30 minutes until the end of the test. If the second stop occurs at 30 minutes, the repellent effect duration is determined to be 0 minutes, and if the second stop occurs at 60 minutes, the repellent effect duration is determined to be 30 minutes. The test was conducted on three subjects, and the average duration of the repellent effect was calculated.
In this test, the concentration of the pest repellent that exhibits a repellent effect duration of 2 hours or more on average can be defined as the effective concentration (effective amount) of the pest repellent.
Moreover, since the composition of the present invention has a sustained repelling effect even if it does not contain an effective amount of existing pest repellents, it is preferable that it does not substantially contain any pest repellents other than component (A). . In the composition of the present invention, the content of pest repellents other than component (A) is preferably 0.5% by mass or less, more preferably 0.1% by mass or less, even more preferably 0.01% by mass or less, Even more preferably, it is substantially 0% by mass.

Existing pest repellents other than component (A) include DEET, icaridin, dimethyl phthalate, 2-ethyl-1,3-hexanediol, p-menthane-3,8-diol, caran-3,4-diol, Known compounds such as di-n-butyl succinate, hydroxyanisole, rotenone, 3-(acetylbutyl)aminopropionic acid ethyl ester, citronellol, eucalyptol, α-pinene, geraniol, citronellal, camphor, linalool, 2-undecanone, etc. In addition to insect repellent compounds, repellent essential oils such as citronella oil and lemongrass oil may be mentioned. The term "repellent essential oil" refers to essential oils obtained by extracting, distilling, pressing, etc. components contained in plants that have a pest repellent effect.

<Production method of composition>
The composition of the present invention can be prepared by conventional methods.
For example, a non-aqueous composition can be produced by first mixing component (A) with component (B) and, if necessary, a volatile oil, and stirring the mixture with a stirring device such as a disperser to prepare a dispersion. Next, other components are mixed as necessary, and the mixture is stirred with a stirring device such as a homogenizer.

Water-in-oil compositions are prepared by mixing component (B) with component (A) and stirring with a stirring device such as a disper to prepare a dispersion, and then adding water and other ingredients as necessary. It can be produced by blending the ingredients and stirring using a stirring device such as a homogenizer.

The composition of the present invention is not particularly limited to the pests to be repelled, but is more effective against flying pests. "Flying pests" refers to pests that fly close to animals such as humans and suck blood from their skin, pests that fly but do not suck blood but transmit pathogenic bacteria, and pests whose flying behavior itself is unpleasant to humans.
Specific examples of flying pests include mosquitoes such as Culex pipiens quinquefasciatus, Culex tritaeniorhynchus, Culex pipiens molestus, Culex quinquefasciatus, and Culex quinquefasciatus; midges such as Culicidae tokunaga, Culicidae oshimaensis, and Culicidae quinquefasciatus; midges such as Chironomidae and Chironomidae akamusi; and mosquitoes such as Aedes aegypti, Aedes albopictus, Aedes togoi, Anopheles sinensis, Anopheles gambiae, and Anopheles stephensis; midges such as the Japanese bush cricket; blackflies such as the Japanese giant fly, the Japanese bush cricket, and the Japanese hawk moth; flies such as the house fly, the giant house fly, the little house fly, the black fly, the flesh fly, the seed fly, the onion fly, the fruit fly, the Drosophila melanogaster, the moth fly, the stable fly, and other flies; horse flies such as the black hornet, the horse fly, the deer fly, and the spotted fly; and bees such as the Japanese yellow hornet, the Japanese paper wasp, and the honeybee.
The composition of the present invention is particularly effective in providing a long-lasting repellent effect against mosquitoes, particularly Culex pipiens pallens, Culex tritaeniorhynchus, Culex pipiens quinquefasciatus, Aedes aegypti, and Aedes albopictus.

[How to avoid pests, how to suppress their retention]
The pest repellent method of the present invention is carried out by applying the pest repellent composition of the present invention to the surface of human skin. Furthermore, the method for inhibiting retention of pests of the present invention is to prevent pests from retaining on human skin by attaching the composition for inhibiting retention of pests of the present invention to the limbs of pests, particularly flying pests. Hereinafter, these methods will also be collectively referred to as the "method of the present invention."

Here, "applying to the skin surface" includes not only directly applying the composition to the skin surface by hand, but also adhering the composition to the skin surface by spraying or the like.
The amount of the composition applied to the skin surface is preferably 0.1 mg or more, more preferably 0.2 mg or more, and still more preferably 0.25 mg or more per 1 cm ² from the viewpoint of improving the lasting repellent effect. . Further, the upper limit of the application amount is preferably 10 mg or less, more preferably 8 mg or less, still more preferably 5 mg or less per 1 cm ² from the viewpoint of providing a good feel when applied to the skin.

The composition of the present invention contains the following components (A) and (B) from the viewpoint of providing a repellent composition that is safe, feels good when applied to the skin, and has an excellent long-lasting effect of repelling flying pests. However, it is preferably a water-in-oil or non-aqueous flying pest repellent composition or a flying pest retention suppressing composition in which the content of pest repellents other than component (A) is 15% by mass or less.
(A) silicone oil, ester oil, ether oil, hydrocarbon oil, aliphatic alcohol, which has a surface tension of 40 mN/m or less at 25°C and a viscosity of 400 mPa·s or less at 23°C measured by a B-type rotational viscometer; One or more nonvolatile liquid oil components selected from the group consisting of polyhydric alcohols: 50% by mass or more and 99.5% by mass or less (B) Hydrophobic particles with a volume median particle size of 0.1 μm or more and 40 μm or less: 0 .5 mass% or more and 35 mass% or less

The composition of the present invention contains the following components (A) and (B) from the viewpoint of providing a repellent composition that is safe, feels good when applied to the skin, and has an excellent long-lasting effect of repelling mosquitoes. , a water-in-oil type or non-aqueous type mosquito repellent composition or mosquito retention suppressing composition in which the content of pest repellents other than component (A) is 15% by mass or less is preferable.
(A) silicone oil, ester oil, ether oil, hydrocarbon oil, aliphatic alcohol, which has a surface tension of 40 mN/m or less at 25°C and a viscosity of 400 mPa·s or less at 23°C measured by a B-type rotational viscometer; One or more nonvolatile liquid oil components selected from the group consisting of polyhydric alcohols: 50% by mass or more and 99.5% by mass or less (B) Hydrophobic particles with a volume median particle size of 0.1 μm or more and 40 μm or less: 0 .5 mass% or more and 35 mass% or less

The composition of the present invention contains the following components (A) and (B) from the viewpoint of providing a repellent composition that is safe, feels good when applied to the skin, and has an excellent long-lasting effect of repelling flying pests. However, it is preferably a water-in-oil or non-aqueous flying pest repellent composition or a flying pest retention suppressing composition in which the content of caran-3,4-diol is 3% by mass or less.
(A) silicone oil, ester oil, ether oil, hydrocarbon oil, aliphatic alcohol, which has a surface tension of 40 mN/m or less at 25°C and a viscosity of 400 mPa·s or less at 23°C measured by a B-type rotational viscometer; One or more nonvolatile liquid oil components selected from the group consisting of polyhydric alcohols: 50% by mass or more and 99.5% by mass or less (B) Hydrophobic particles with a volume median particle size of 0.1 μm or more and 40 μm or less: 0 .5 mass% or more and 35 mass% or less

The composition of the present invention contains the following components (A), component (B), and water from the viewpoint of providing a repellent composition that is safe, feels good when applied to the skin, and has an excellent long-lasting effect of repelling mosquitoes. A water-in-oil type flying pest repellent composition, which contains: Alternatively, it is preferably a composition for suppressing the retention of flying pests.
(A) silicone oil, ester oil, ether oil, hydrocarbon oil, aliphatic alcohol, which has a surface tension of 40 mN/m or less at 25°C and a viscosity of 400 mPa·s or less at 23°C measured by a B-type rotational viscometer; One or more nonvolatile liquid oil components selected from the group consisting of polyhydric alcohols: 50% by mass or more and 96.5% by mass or less (B) Hydrophobic particles with a volume median particle size of 0.1 μm or more and 40 μm or less: 0 .5 mass% or more and 35 mass% or less

The composition of the present invention contains the following components (A) and (B) from the viewpoint of providing a repellent composition that is safe, feels good when applied to the skin, and has an excellent long-lasting effect of repelling mosquitoes. , the mass ratio [(A)/(B)] of component (A) and component (B) is 1 or more and 30 or less, and the content of pest repellents other than component (A) is 15% by mass or less , a water-in-oil type or a non-aqueous type mosquito repellent composition or a mosquito retention suppressing composition.
(A) silicone oil, ester oil, ether oil, hydrocarbon oil, aliphatic alcohol, which has a surface tension of 40 mN/m or less at 25°C and a viscosity of 400 mPa·s or less at 23°C measured by a B-type rotational viscometer; One or more non-volatile liquid oil components selected from the group consisting of polyhydric alcohols: 50% by mass or more and 99.5% by mass or less (B) Hydrophobic particles with a volume median particle size of 0.5 μm or more and 30 μm or less: 0.5% by mass or more and 35% by mass or less

In the above composition, component (B) more preferably contains resin particles made of one or more resins selected from the group consisting of silicone resins, acrylic resins, and polyurethane resins.

The pest repelling method of the present invention is a method for repelling pests by preventing pests such as mosquitoes from remaining on the spot even if they land on an object to which the composition of the present invention has been applied or attached. Specifically, the method has a retention inhibition effect in which pests such as mosquitoes do not remain on the surface of an animal's skin for a period of time after landing on the skin of an animal such as a human, such as for a period of time that they can insert their stingers, specifically for example, for one second or more. This effect is based on a novel pest repelling principle, and is safe with no side effects such as rough skin.

Regarding the above embodiments, the present invention further discloses the following embodiments.
<1>
Water-in-oil type or non-oil type containing the following component (A) and component (B), and the mass ratio [(A)/(B)] of component (A) and component (B) is 1 or more and 30 or less. A water-type pest repellent composition or pest retention suppressing composition.
(A) silicone oil, ester oil, ether oil, hydrocarbon oil, aliphatic alcohol, which has a surface tension of 40 mN/m or less at 25°C and a viscosity of 400 mPa·s or less at 23°C measured by a B-type rotational viscometer; One or more nonvolatile liquid oil components selected from the group consisting of polyhydric alcohols: 50% by mass or more and 99.5% by mass or less (B) Hydrophobic particles with a volume median particle size of 0.1 μm or more and 40 μm or less: 0.5% by mass or more and 35% by mass or less <2>
The mass ratio [(A)/(B)] of component (A) and component (B) is preferably 2 or more, more preferably 4 or more, and preferably 15 or less, more preferably 8 or less. 1>.
<3>
The content of pest repellents other than component (A) is 15% by mass or less, preferably 10% by mass or less, more preferably 5% by mass or less, even more preferably 3% by mass or less, even more preferably 2% by mass or less, The composition according to <1> or <2>, which is even more preferably 1% by mass or less.
<4>
The surface tension of component (A) at 25°C is preferably 15 mN/m or more, more preferably 17 mN/m or more, preferably 30 mN/m or less, more preferably 28 mN/m or less, and even more preferably 25 mN/m or less. , more preferably 23 mN/m or less, even more preferably 21 mN/m or less, the composition according to any one of <1> to <4>.
<5>
The viscosity of component (A) at 23°C measured by a B-type rotational viscometer is preferably 1 mPa·s or more, preferably 300 mPa·s or less, more preferably 210 mPa·s or less, even more preferably 100 mPa·s or less, and more. The composition according to any one of <1> to <4>, which is more preferably 60 mPa·s or less, even more preferably 45 mPa·s or less, even more preferably 30 mPa·s or less.
<6>
Component (A) is one or more selected from the group consisting of silicone oil, ester oil, ether oil, and hydrocarbon oil, preferably one or more selected from the group consisting of silicone oil, ester oil, and hydrocarbon oil, The composition according to any one of <1> to <5>, more preferably one or more selected from the group consisting of silicone oil and hydrocarbon oil, and even more preferably silicone oil.
<7>
The content of component (A) is preferably 55% by mass or more, more preferably 60% by mass or more, even more preferably 65% by mass or more, and preferably 96.5% by mass or less, more preferably 95% by mass or less, The composition according to any one of <1> to <6>, which is more preferably 90% by mass or less, even more preferably 80% by mass or less, even more preferably 75% by mass or less.
<8>
Component (B) is preferably an acrylic resin, silicone resin, polystyrene resin, polyamide resin, polyester resin, polyolefin resin, polystyrene resin, polyurethane resin, vinyl resin, urea resin, phenol resin, fluororesin, melamine resin, epoxy resin, polycarbonate. Resin particles composed of one or more resins selected from the group consisting of resin, acrylic-silicone copolymer resin, acrylic-styrene copolymer resin, and cellulose, more preferably acrylic resin, silicone resin, polyurethane resin, and cellulose. Resin particles made of one or more resins selected from the group consisting of, more preferably resin particles made of one or more resins selected from the group consisting of acrylic resins, silicone resins, and polyurethane resins. The composition according to any one of <1> to <7>, comprising resin particles preferably composed of one or more resins selected from the group consisting of acrylic resins and silicone resins.
<9>
The content of component (B) is preferably 2% by mass or more, more preferably 4% by mass or more, even more preferably 6% by mass or more, even more preferably 10% by mass or more, and preferably 30% by mass or less, more preferably The composition according to any one of <1> to <8>, wherein the content is preferably 25% by mass or less, more preferably 20% by mass or less.
<10>
Any of <1> to <9>, wherein the volume median particle size of component (B) is preferably 0.5 μm or more, more preferably 1.0 μm or more, and preferably 30 μm or less, more preferably 15 μm or less. The composition according to item 1.

<11>
In the particle size distribution curve of component (B) measured using a light scattering particle size distribution measuring device, the volume ratio of particle sizes of 45 μm or more to the total volume of particles is 15% or less, preferably 10% or less The composition according to any one of <1> to <10>.
<12>
The composition according to any one of <1> to <11>, which is a water-in-oil composition.
<13>
The content of water is 3% by mass or more, preferably 6% by mass or more, more preferably 10% by mass or more, even more preferably 12% by mass or more, and less than 30% by mass, preferably 25% by mass or less, more preferably is 21% by mass or less, more preferably 18% by mass or less, the composition according to <12>.
<14>
The mass ratio of component (A) and water [component (A)/water] is preferably 1 or more, more preferably 3 or more, still more preferably 3.2 or more, even more preferably 4 or more, and preferably 8 The composition according to <12> or <13>, which is more preferably 7 or less, further preferably 6.5 or less, even more preferably 6 or less.
<15>
Furthermore, a surfactant is preferably 0.01% by mass or more, more preferably 0.05% by mass or more, even more preferably 0.1% by mass or more, and preferably 10% by mass or less, more preferably 7% by mass. The composition according to any one of <1> to <14>, further preferably containing 5% by mass or less.
<16>
The composition according to <15>, wherein the surfactant is a nonionic surfactant with an HLB of 8 or less, preferably 6 or less, more preferably 5.5 or less, and preferably 3 or more.
<17>
Nonionic surfactants include polyoxyethylene glycerin fatty acid ester, polyglycerin fatty acid ester, sorbitan fatty acid ester, polyoxyethylene hydrogenated castor oil, propylene glycol fatty acid ester, polyoxyethylene alkyl ether, polyoxyethylene polyoxypropylene alkyl ether, alkyl alkanolamide , fatty acid alkanolamide, polyoxyethylene alkylamine, polyether-modified silicone, and glycerin-modified silicone, preferably polyether-modified silicone, more preferably linear polyoxyethylene/methylpolymer. The composition according to <16>, which is one or more selected from the group consisting of a siloxane copolymer, a linear poly(oxyethylene/oxypropylene) methylpolysiloxane copolymer, and a modified product thereof.
<18>
Furthermore, volatile oil is preferably 1% by mass or more, more preferably 5% by mass or more, even more preferably 10% by mass or more, and preferably 40% by mass or less, more preferably 30% by mass or less, still more preferably 25% by mass or less. The composition according to any one of <1> to <17>, containing at most % by mass, more preferably at most 20% by mass.
<19>
A method for repelling pests, which comprises applying the composition according to any one of <1> to <18> to a human skin surface.
<20>
A method for inhibiting retention of pests, which prevents pests from retaining on human skin by attaching the composition according to any one of <1> to <18> to the limbs of pests.

The present invention will be described below with reference to examples, but the present invention is not limited to the scope of the examples. In the examples, various measurements and evaluations were performed by the following methods.

(Surface tension of liquid oily component)
The surface tension of the liquid oily component is the surface tension measured in an environment of 25° C. by the Wilhelmy method using a platinum plate using an automatic surface tension meter “Tensiometer K100” manufactured by KRUSS.

(Viscosity of Liquid Oily Component)
A Viscometer TVB-10 manufactured by Toki Sangyo Co., Ltd. was used as a B-type rotational viscometer according to JIS K7117-1:1999. The viscosity values of the components to be measured vary greatly for each sample, so it is difficult to accurately measure all of them under one measurement condition. Therefore, measurements were performed using two types of rotors. The viscosity was first measured using rotor M2 at a rotation speed of 12 rpm in an environment of 23°C. On the other hand, components with a viscosity of 20 mPa·s or less were measured again using L adapter, a rotor for low viscosity, at a rotation speed of 30 rpm in an environment of 23°C, to obtain the viscosity value.

(Wetting tension on particle surface)
The measurement was carried out as follows using a mixed liquid for wet tension test made by Fujifilm Wako Pure Chemical Industries, Ltd.
In a 23°C environment, wetting tension test mixture No. 70 (surface tension 70 mN/m) was weighed into a container. Thereafter, 0.01 g of particles to be measured were gently added to the mixed solution. 30 seconds after the particles were added, it was visually confirmed whether the particles got wet with the liquid mixture, and if the particles got wet, it was determined that the wetting tension on the particle surface was 70 mN/m or less. Since the surface tension of water is 70 mN/m, particles were determined to be hydrophobic if the wetting tension on the surface was 70 mN/m or less. The particle surface being wetted by the liquid mixture means that the liquid mixture permeates the particles. The state in which the particles are not wetted by the mixed liquid means that even if the particles and the mixed liquid are mixed, the particles are separated from the mixed liquid (or are repelled).
The wetting tension on the surface of each particle was measured by conducting the above-mentioned test using the following wetting tension test mixture. For example, in the above test, the surface tension of the particle surface is 22.6 mN/m, which is the No. 1 liquid mixture for wetting tension test. 25.4 (surface tension 25.4 mN/m), the particle surface was not wetted by the mixed liquid, and No. 25.4 (surface tension 25.4 mN/m) was used. 22.6 (surface tension 22.6 mN/m) means that the particle surface was wetted by the mixed liquid.
<Fujifilm Wako Pure Chemical Industries, Ltd.'s wet tension test mixture>
No. 70 (surface tension 70 mN/m), No. 67 (surface tension 67 mN/m), No. 64 (surface tension 64 mN/m), No. 62 (surface tension 62 mN/m), No. 60 (surface tension 60 mN/m), No. 59 (surface tension 59 mN/m), No. 52 (surface tension 52 mN/m), No. 50 (surface tension 50 mN/m), No. 48 (surface tension 48 mN/m), No. 46 (surface tension 46 mN/m), No. 44 (surface tension 44 mN/m), No. 42 (surface tension 42 mN/m), No. 40 (surface tension 40 mN/m), No. 38 (surface tension 38 mN/m), No. 36 (surface tension 36 mN/m), No. 34 (surface tension 34 mN/m), No. 32 (surface tension 32 mN/m), No. 30 (surface tension 30 mN/m), No. 27.3 (surface tension 27.3 mN/m), No. 25.4 (surface tension 25.4 mN/m), No. 22.6 (Surface tension 22.6 mN/m)

(Volume median particle size)
For the particles (B2), (B3), (B4), (b1), and (b2) shown in Table 1, the volume median particle diameter (D50) of the particles is determined by Horiba's laser diffraction/ The measurement was performed using a scattering particle size distribution analyzer "LA-920" using ethanol/water (99.5% by mass/0.5% by mass) as a dispersion medium. In addition, the relative refractive index when measuring particles (B2), (B4), and (b1) was 1.05-0.000i, and the relative refractive index when measuring particles (b2) was 1.05-0.000i. 07-0.000i, and the relative refractive index when measuring the particles of (B3) was 1.10-0.000i.
Regarding particles (B1) shown in Table 1, ethanol/water (99.5% by mass/0. 5% by mass) as a dispersion medium, and the relative refractive index was measured as 1.05-0.000i.

(particle size distribution)
The particle size distribution of particles (B2), (B3), (B4), (b1), and (b2) shown in Table 1 was determined by laser diffraction/scattering particle size distribution measurement by Horiba, Ltd. Using the device "LA-920", measurements were made on a particle size basis (volume) using ethanol/water (99.5% by mass/0.5% by mass) as a dispersion medium. The relative refractive index when measuring particles (B2), (B4), and (b1) was 1.05-0.000i, and the relative refractive index when measuring particles (b2) was 1.07- 0.000i was used, and the relative refractive index when measuring the particles of (B3) was 1.10-0.000i. At that time, in the chart obtained by the measurement, the area of each particle size range was determined, and the volume ratio of the particle size of 45 μm or more to the total volume of the particles was determined from the area ratio.
Regarding the particles (B1) shown in Table 1, ethanol/water (99% 0.5% by mass/0.5% by mass) as a dispersion medium and a relative refractive index of 1.05-0.000i.

(Evaluation of sustained effect of repelling pests)
(I) Preparation of Aedes albopictus Aedes albopictus eggs purchased from Sumitomo Techno Service Co., Ltd. were reared in a cage at 27°C and 60% relative humidity (RH), and grown into adults. .
A transparent plastic pan was filled with about 1 cm of water, filter paper containing purchased eggs was placed in the pan, and the eggs were hatched into pupae. Thereafter, the hatched pupae were fed tropical fish food (tetramine) as larval food every day. One week later, the pupae were collected with a dropper, transferred to a 20 mL plastic cup, and transferred to a meshed cage. The pupae were given 10% by mass sucrose in a 25 mL plastic tube as food for adults. After emergence, males and females were kept in the same cage for 5 days to allow mating. After 5 days of rearing, adult worms were collected using a fluke tube, anesthetized on ice for 5 minutes, and then visually separated into males and females, and only females were collected and used for evaluation.

(II) Measurement of duration of repellent effect Approximately 100 female Aedes albopictus mosquitoes were transferred to a plastic cage (30 x 30 x 30 cm), and a test was conducted under conditions of 27° C. and 60% relative humidity (RH). A hole measuring 4 x 5 cm was made in the forearm of a rubber glove large enough to cover the subject's arm, and the composition of each example was uniformly applied at a concentration of 2 mg/cm ² . Then, to activate the Aedes albopictus mosquitoes, breath was blown onto the plastic gauge for 5 seconds. In the test, the forearm immediately after applying the composition was exposed to Aedes albopictus mosquitoes for 2 minutes by placing it in a plastic gauge, and the number of mosquitoes that remained (the number of mosquitoes that remained in contact for more than 1 second after landing on the forearm) was counted. I went there. The test was terminated when the test was stopped twice in total, and exposure was continued for 2 minutes every 30 minutes until the end of the test. If the second retention occurs during the 30th minute of exposure, the repellent effect duration is determined to be 0 minutes, and if the second retention occurs during the 60th minute exposure, the repellent effect duration is determined to be 30 minutes. It was determined that The test was conducted on three subjects, and the average duration of the repellent effect was calculated.

(Evaluation of texture (smooth feeling when applied to skin))
Three expert panelists applied 0.02 mL of each composition to a 3 cm diameter circle on the inside of the forearm, and spread it evenly over 1 minute under conditions of 25°C and 57% RH. A sensory evaluation was performed on the smooth feeling from the time of drying to after drying using a 5-point scale according to the following criteria, and the average scores of the three panelists (rounded off to the first decimal place) are shown in the table. The evaluation result of Comparative Example 1 was set to "1".
5: No sticky feeling at all, and a good, smooth feel.
4: Feels slightly sticky, but has a smooth feel.
3: Some stickiness is felt, but the feeling is more of a dry texture.
2: Feels sticky, but has a smooth feel.
1: Feels sticky and lacks a smooth feel.

(Storage stability evaluation)
Pour 100 mL of the composition of each example into a 110 mL glass bottle (As One Co., Ltd. "Mighty Vial No. 8 Transparent", mouth inner diameter x body diameter x total length x wall thickness = Φ20.3 x Φ40 x 120 x 1.3 mm). After the container was sealed and stored at 50° C. for one week, the degree of sedimentation of the powder was visually confirmed. The degree of sedimentation of the powder was evaluated according to the following criteria.
A: No sedimentation of powder was observed.
B: The bulk of the powder layer is 70 mL or more and less than 100 mL, suppressing sedimentation of the powder.
C: The bulk of the powder layer is 50 mL or more and less than 70 mL, suppressing sedimentation of the powder.
D: The bulk of the powder layer is less than 50 mL, and sedimentation of the powder cannot be suppressed.

Production Example 1 (Production of Dimethylsilylated Cellulose Particles (b2))
Cellulose particles CELLULOBEADS D-50 (Daito Kasei Kogyo Co., Ltd., 50 μm spherical cellulose) were weighed in a 2000 mL separable flask at 100.00 g of water content, and in order to remove moisture from the cellulose particles, the mixture was heated and vacuum dried at 80 ° C until the final moisture value was 1 mass% or less. 600 mL of ultra-dehydrated N,N-dimethylformamide (FUJIFILM Wako Pure Chemical Industries Co., Ltd.) was added to the 2000 mL separable flask containing the dried cellulose particles, and after stirring at room temperature for 30 minutes, 10.00 g of chlorodimethylsilane (Tokyo Kasei Kogyo Co., Ltd.) was gradually added dropwise. After the addition, the internal temperature was raised to 80 ° C. in a water bath and reacted for 4 hours. After the reaction was completed, the reaction solution was filtered and separated, and the filtrate was washed with acetone. Thereafter, the filtered material was vacuum-dried at 80° C. for one day to obtain dimethylsilylated cellulose particles (b2), which are hydrophobic particles having a volume median particle size (D50) of 45.2 μm.

Examples 1 to 18, Comparative Examples 1 to 5 (preparation and evaluation of non-aqueous compositions)
Each component shown in Table 1 was blended in the amounts shown in Tables 2 to 4 and Table 6, and T. K. The stirring section of Robomix (Tokushu Kika Kogyo Co., Ltd.) was replaced with T. K. A non-aqueous composition of each example was obtained through a step of stirring at 8,000 rpm for 2 minutes using a homomixer MARK II type 2.5. Using the obtained composition, various evaluations were performed according to the methods described above. The results are shown in Tables 2 to 4 and Table 6.

Examples 19-21 (Preparation and Evaluation of Water-in-Oil Compositions)
Among the components shown in Table 5, component (A), component (B), and volatile oil were blended and mixed using a T.K. Robomix (Tokushu Kika Kogyo Co., Ltd.) with the stirring part replaced with a T.K. Homo Disper 2.5 type. The amounts of water and surfactant shown in Table 5 were blended therein, and the stirring part of the T.K. Robomix (Tokushu Kika Kogyo Co., Ltd.) was replaced with a T.K. Homo Mixer MARK II2.5 type, and the mixture was stirred at 8,000 rpm for 2 minutes to obtain a water-in-oil composition of each example. The obtained composition was used to perform various evaluations using the above-mentioned methods. The results are shown in Table 5.

The notations (A) and (B) listed in the table correspond to component (A) and component (B) in this specification, respectively, and the notations (a) and (b) respectively correspond to components in this specification. It corresponds to non-volatile liquid oily components outside the range of (A) and particles outside the range of component (B). The amounts listed in each table are the active ingredient amounts (% by mass) of each component.

From Tables 2 to 6, the compositions of the present invention (Examples 1 to 21) containing predetermined amounts of component (A) and component (B) maintain a sustained repellent effect for a longer period of time than Comparative Examples 1 to 5. It can be seen that the sample has a better feel than Comparative Example 1.

According to the present invention, it is possible to provide a water-in-oil or non-aqueous pest repellent composition, a water-in-oil or non-aqueous pest retention and inhibition composition, a pest repellent method, and a pest retention and inhibition method, which are safe, have a pleasant feel when applied to the skin, and have excellent sustained repellent effects against pests, particularly flying pests.
According to the present invention, a composition and method having a pest repellent effect that is safe, environmentally friendly, and can be used by anyone with peace of mind can be provided at low cost. Therefore, the present invention can contribute to the resolution of Goal 3 "Good health and well-being for all," Goal 6 "Clean water and sanitation for all," and Goal 13 "Climate action" out of the 17 Sustainable Development Goals (SDGs), and is believed to contribute to the realization of a society in which everyone in the world is free from the troubles caused by pests.

Claims (4)

A water-in-oil or non-aqueous pest repellent composition containing the following components (A) and (B).
(A) One or more non-volatile liquid oil components selected from dimethylpolysiloxane and squalane, which have a surface tension of 40 mN/m or less at 25°C and a viscosity of 400 mPa·s or less at 23°C measured by a B-type rotational viscometer: 50% by mass or more and 99.5% by mass or less (B) Hydrophobic particles with a volume median particle size of 0.1 μm or more and 40 μm or less and a particle surface wetting tension of 70 mN/m or less at 23°C: 0.5 mass % or more and 35% by mass or less A water-in-oil or non-aqueous insect pest retention composition containing the following components (A) and (B).
(A) One or more non-volatile liquid oil components selected from dimethylpolysiloxane and squalane, which have a surface tension of 40 mN/m or less at 25°C and a viscosity of 400 mPa·s or less at 23°C measured by a B-type rotational viscometer: 50% by mass or more and 99.5% by mass or less (B) Hydrophobic particles with a volume median particle size of 0.1 μm or more and 40 μm or less and a particle surface wetting tension of 70 mN/m or less at 23°C: 0.5 mass % or more and 35% by mass or less The composition according to claim 1 or 2, wherein component (B) contains resin particles composed of one or more resins selected from the group consisting of acrylic resins, silicone resins, and polyurethane resins. The composition according to any one of claims 1 to 3, which is a water-in-oil composition and has a water content of 3% by mass or more and less than 30% by mass.