JP7454492B2 - 皮膚障害に対する光線力学的治療方法 - Google Patents

皮膚障害に対する光線力学的治療方法 Download PDF

Info

Publication number
JP7454492B2
JP7454492B2 JP2020503004A JP2020503004A JP7454492B2 JP 7454492 B2 JP7454492 B2 JP 7454492B2 JP 2020503004 A JP2020503004 A JP 2020503004A JP 2020503004 A JP2020503004 A JP 2020503004A JP 7454492 B2 JP7454492 B2 JP 7454492B2
Authority
JP
Japan
Prior art keywords
topical composition
light
minutes
skin
acne
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2020503004A
Other languages
English (en)
Japanese (ja)
Other versions
JP2020527592A (ja
JP2020527592A5 (enExample
Inventor
ウィリー,アンドレア
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dusa Pharmaceuticals Inc
Original Assignee
Dusa Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=65016221&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP7454492(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Dusa Pharmaceuticals Inc filed Critical Dusa Pharmaceuticals Inc
Publication of JP2020527592A publication Critical patent/JP2020527592A/ja
Publication of JP2020527592A5 publication Critical patent/JP2020527592A5/ja
Priority to JP2024011940A priority Critical patent/JP7734222B2/ja
Application granted granted Critical
Publication of JP7454492B2 publication Critical patent/JP7454492B2/ja
Priority to JP2025139643A priority patent/JP2025176048A/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0052Thermotherapy; Hyperthermia; Magnetic induction; Induction heating therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/00615-aminolevulinic acid-based PDT: 5-ALA-PDT involving porphyrins or precursors of protoporphyrins generated in vivo from 5-ALA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0613Apparatus adapted for a specific treatment
    • A61N5/0616Skin treatment other than tanning
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0613Apparatus adapted for a specific treatment
    • A61N5/062Photodynamic therapy, i.e. excitation of an agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0658Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0662Visible light
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/02Radiation therapy using microwaves
    • A61N5/022Apparatus adapted for a specific treatment
    • A61N5/025Warming the body, e.g. hyperthermia treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0613Apparatus adapted for a specific treatment
    • A61N5/0625Warming the body, e.g. hyperthermia treatment

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pathology (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Biochemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Radiation-Therapy Devices (AREA)
  • Medicinal Preparation (AREA)
JP2020503004A 2017-07-17 2018-07-17 皮膚障害に対する光線力学的治療方法 Active JP7454492B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2024011940A JP7734222B2 (ja) 2017-07-17 2024-01-30 皮膚障害に対する光線力学的治療方法
JP2025139643A JP2025176048A (ja) 2017-07-17 2025-08-25 皮膚障害に対する光線力学的治療方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762533558P 2017-07-17 2017-07-17
US62/533,558 2017-07-17
US201762534973P 2017-07-20 2017-07-20
US62/534,973 2017-07-20
PCT/US2018/042505 WO2019018408A1 (en) 2017-07-17 2018-07-17 METHOD OF PHOTODYNAMIC THERAPY AGAINST SKIN DISORDERS

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024011940A Division JP7734222B2 (ja) 2017-07-17 2024-01-30 皮膚障害に対する光線力学的治療方法

Publications (3)

Publication Number Publication Date
JP2020527592A JP2020527592A (ja) 2020-09-10
JP2020527592A5 JP2020527592A5 (enExample) 2021-12-02
JP7454492B2 true JP7454492B2 (ja) 2024-03-22

Family

ID=65016221

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2020503004A Active JP7454492B2 (ja) 2017-07-17 2018-07-17 皮膚障害に対する光線力学的治療方法
JP2024011940A Active JP7734222B2 (ja) 2017-07-17 2024-01-30 皮膚障害に対する光線力学的治療方法
JP2025139643A Pending JP2025176048A (ja) 2017-07-17 2025-08-25 皮膚障害に対する光線力学的治療方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2024011940A Active JP7734222B2 (ja) 2017-07-17 2024-01-30 皮膚障害に対する光線力学的治療方法
JP2025139643A Pending JP2025176048A (ja) 2017-07-17 2025-08-25 皮膚障害に対する光線力学的治療方法

Country Status (7)

Country Link
US (2) US20200261580A1 (enExample)
EP (1) EP3655035A4 (enExample)
JP (3) JP7454492B2 (enExample)
AU (2) AU2018302103B2 (enExample)
CA (1) CA3070107A1 (enExample)
IL (2) IL301904A (enExample)
WO (1) WO2019018408A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3851161A1 (en) 2015-10-15 2021-07-21 DUSA Pharmaceuticals, Inc. Adjustable illuminator for photodynamic therapy and diagnosis
US10603508B2 (en) 2015-10-15 2020-03-31 Dusa Pharmaceuticals, Inc. Adjustable illuminators and methods for photodynamic therapy and diagnosis
US10357567B1 (en) * 2018-01-12 2019-07-23 Dusa Pharmaceuticals, Inc. Methods for photodynamic therapy
EP3714879A1 (en) 2019-03-28 2020-09-30 Sisaf Ltd Structured encapsulated silicon-containing particles
GB201904336D0 (en) 2019-03-28 2019-05-15 Sisaf Ltd A delivery system
GB201904334D0 (en) 2019-03-28 2019-05-15 Sisaf Ltd Carrier system for preparing herbaceous extracts
WO2023079513A1 (en) 2021-11-05 2023-05-11 Dusa Pharmaceuticals, Inc. Photodynamic therapy illuminator devices and methods
JP2025537694A (ja) 2022-11-04 2025-11-20 サン ファーマシューティカル インダストリーズ,インコーポレイテッド 光線力学的療法の方法
KR20250001702A (ko) * 2023-06-29 2025-01-07 주식회사 루트로닉 여드름 치료를 위한 레이저 치료 장치 및 이를 이용한 치료 방법
WO2025046471A1 (en) * 2023-08-28 2025-03-06 Sun Pharmaceutical Industries, Inc. Photodynamic therapy in combination with an hedgehog pathway inhibitor for use in treating non-melanoma skin cancer
WO2025235557A2 (en) 2024-05-07 2025-11-13 Sun Pharmaceutical Industries, Inc. Photodynamic therapy illuminator and photodynamic therapy methods

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002529495A (ja) 1998-11-12 2002-09-10 アサト アクチェンゲゼルシャフト アプライド サイエンス アンド テクノロジー 5−アミノレブリン酸−ナノエマルジヨン
US20090247932A1 (en) 2008-04-01 2009-10-01 Daniel Barolet Method for the treatment of skin tissues
JP2010515714A (ja) 2007-01-11 2010-05-13 フォトキュア エイエスエイ アミノレブリン酸およびその誘導体の使用
US20110224598A1 (en) 2010-03-12 2011-09-15 Daniel Barolet Radiant near infrared light emitting diode exposure as skin preparation
US20130274834A1 (en) 2006-04-18 2013-10-17 Daniel Barolet Method for the treatment of skin tissues.
US20150290028A1 (en) 2013-01-23 2015-10-15 Jonathan Isserow Heating device and method of use

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5079262A (en) * 1989-07-28 1992-01-07 Queen's University At Kingston Method of detection and treatment of malignant and non-malignant lesions utilizing 5-aminolevulinic acid
US5814008A (en) * 1996-07-29 1998-09-29 Light Sciences Limited Partnership Method and device for applying hyperthermia to enhance drug perfusion and efficacy of subsequent light therapy
GB0424833D0 (en) * 2004-11-10 2004-12-15 Photocure Asa Method
EP1938801A1 (en) * 2006-12-22 2008-07-02 Biofrontera Bioscience GmbH Nanoemulsion
WO2009003173A1 (en) * 2007-06-27 2008-12-31 The General Hospital Corporation Method and apparatus for optical inhibition of photodymanic therapy
JP5964322B2 (ja) * 2011-01-13 2016-08-03 キュー エル ティー インク.QLT Inc. 光増感剤の局所送達用医薬組成物及びその使用
US20140067024A1 (en) * 2012-08-30 2014-03-06 Photocure Asa Dual panel photodynamic therapy lamp

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002529495A (ja) 1998-11-12 2002-09-10 アサト アクチェンゲゼルシャフト アプライド サイエンス アンド テクノロジー 5−アミノレブリン酸−ナノエマルジヨン
US20130274834A1 (en) 2006-04-18 2013-10-17 Daniel Barolet Method for the treatment of skin tissues.
JP2010515714A (ja) 2007-01-11 2010-05-13 フォトキュア エイエスエイ アミノレブリン酸およびその誘導体の使用
US20090247932A1 (en) 2008-04-01 2009-10-01 Daniel Barolet Method for the treatment of skin tissues
US20110224598A1 (en) 2010-03-12 2011-09-15 Daniel Barolet Radiant near infrared light emitting diode exposure as skin preparation
US20150290028A1 (en) 2013-01-23 2015-10-15 Jonathan Isserow Heating device and method of use

Also Published As

Publication number Publication date
EP3655035A1 (en) 2020-05-27
JP2020527592A (ja) 2020-09-10
JP7734222B2 (ja) 2025-09-04
US20220354952A1 (en) 2022-11-10
AU2018302103B2 (en) 2024-03-07
IL272081A (en) 2020-03-31
WO2019018408A1 (en) 2019-01-24
CA3070107A1 (en) 2019-01-24
AU2018302103A1 (en) 2020-02-06
US20200261580A1 (en) 2020-08-20
IL301904A (en) 2023-06-01
JP2025176048A (ja) 2025-12-03
JP2024050723A (ja) 2024-04-10
AU2024203899A1 (en) 2024-06-27
EP3655035A4 (en) 2021-04-14

Similar Documents

Publication Publication Date Title
JP7734222B2 (ja) 皮膚障害に対する光線力学的治療方法
Clementoni et al. Photodynamic photorejuvenation of the face with a combination of microneedling, red light, and broadband pulsed light
Pariser et al. Topical methyl-aminolevulinate photodynamic therapy using red light-emitting diode light for treatment of multiple actinic keratoses: a randomized, double-blind, placebo-controlled study
Wan et al. Current evidence and applications of photodynamic therapy in dermatology
Itkin et al. δ‐Aminolevulinic acid and blue light photodynamic therapy for treatment of multiple basal cell carcinomas in two patients with nevoid basal cell carcinoma syndrome
Jeffes Levulan®: the first approved topical photosensitizer for the treatment of actinic keratosis
Nguyen et al. An update on topical photodynamic therapy for clinical dermatologists
Cai et al. Photodynamic therapy in combination with CO2 laser for the treatment of Bowen’s disease
Fritsch et al. Fluorescence diagnosis and photodynamic therapy in dermatology from experimental state to clinic standard methods
Barge et al. Correlations between photoactivable porphyrins’ fluorescence, erythema and the pain induced by PDT on normal skin using ALA-derivatives
Mitra et al. Topical photodynamic therapy for non-cancerous skin conditions
Kim et al. Topical photodynamic therapy using intense pulsed light for treatment of actinic keratosis: clinical and histopathologic evaluation
Zhang et al. Conventional versus daylight photodynamic therapy for acne vulgaris: a randomized and prospective clinical study in China
Jorizzo Current and novel treatment options for actinic keratosis
Cai et al. Photodynamic therapy for facial actinic keratosis: a clinical and histological study in Chinese patients
Chen et al. Limitations of ALA-PDT as a reliable therapy for AK in clinical practice
Schleier et al. Comparison of aminolevulinic acid (ALA)-thermogel-PDT with methyl-ALA-thermogel-PDT in basal cell carcinoma
Pires et al. Laser-assisted MAL-PDT associated with acoustic pressure wave ultrasound with short incubation time for field cancerization treatment: A left-right comparison
Borgia et al. Photodynamic therapy for acne conglobata of the buttocks: Effective antiinflammatory treatment with good cosmetic outcome
Wang et al. Clinical trial of two-step photodynamic therapy for reduced pain in the treatment of precancerous squamous lesions (Actinic keratoses)
Cho et al. Topical Methyl Aminolevulinate Photodynamic Therapy in Porokeratosis of Mibelli: An Alternative Treatment for a Refractory Disease
Sidoroff Topical sensitization—oncologic indications—actinic keratoses
Gold Lasers, Photodynamic Therapy, and the Treatment of Medical Dermatologic Conditions
Moore et al. Sustained resolution of nonmelanoma skin cancer with photodynamic therapy using 10% 5-aminolevulinic acid hydrochloride gel: A retrospective case series
Hommel et al. Photodynamic therapy (PDT)

Legal Events

Date Code Title Description
A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A711

Effective date: 20210622

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20210715

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20210622

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20211013

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20220802

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20221027

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20230207

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20230428

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20230801

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20231026

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20240130

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20240213

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20240311

R150 Certificate of patent or registration of utility model

Ref document number: 7454492

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

S111 Request for change of ownership or part of ownership

Free format text: JAPANESE INTERMEDIATE CODE: R313111

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350