JP7442549B2 - 薬物送達デバイス用の組立体、および薬物送達デバイス - Google Patents
薬物送達デバイス用の組立体、および薬物送達デバイス Download PDFInfo
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- JP7442549B2 JP7442549B2 JP2021570345A JP2021570345A JP7442549B2 JP 7442549 B2 JP7442549 B2 JP 7442549B2 JP 2021570345 A JP2021570345 A JP 2021570345A JP 2021570345 A JP2021570345 A JP 2021570345A JP 7442549 B2 JP7442549 B2 JP 7442549B2
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3202—Devices for protection of the needle before use, e.g. caps
- A61M5/3204—Needle cap remover, i.e. devices to dislodge protection cover from needle or needle hub, e.g. deshielding devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M2005/206—With automatic needle insertion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3103—Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle
- A61M2005/3107—Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle for needles
- A61M2005/3109—Caps sealing the needle bore by use of, e.g. air-hardening adhesive, elastomer or epoxy resin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/82—Internal energy supply devices
- A61M2205/8206—Internal energy supply devices battery-operated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/82—Internal energy supply devices
- A61M2205/8275—Mechanical
- A61M2205/8281—Mechanical spring operated
Description
Claims (18)
- 薬物送達デバイス用の組立体であって:
薬物リザーバを受けるためのハウジング(11)を含むハウジングユニットと、
キャップ(12)とを含み、ここで
該キャップ(12)は、ハウジング(11)に対して解放可能に固定可能であり、
組立体は、少なくとも2つの異なる状態、すなわちキャップ(12)がハウジング(11)に対して固定されているキャップ装着状態と、キャップ(12)がハウジング(11)から解放されている、たとえばハウジング(11)から分離している、キャップ脱離状態とを有しており、
キャップ(12)は、ハウジング(11)からキャップ(12)を解放するため、たとえば分離するために、ユーザによって把持されるように構成された外側部材(21)を含み、
該外側部材(21)は、ハウジング(11)からキャップ(12)を解放するためにハウジング(11)に対して回転可能であり、
組立体は、キャップ装着状態からキャップ脱離状態に切り替わるときに、ハウジング(11)に対する外側部材(21)の回転運動を、ハウジング(11)に対する外側部材(21)の軸方向運動に変換するように構成された機械的インターフェースを含み、
該機械的インターフェースは、組立体がキャップ装着状態からキャップ脱離状態に切り替えられるときに、ハウジング(11)に対する外側部材(21)の動きを案内するように構成された少なくとも1つの案内トラック(30)を含むか、それによって形成されており、
該案内トラック(30)は、少なくとも第1の傾き領域(30A)および第2の傾き領域(30B)を有しており、
組立体がキャップ装着状態からキャップ脱離状態に切り替えられるときに、第2の傾き領域(30B)が外側部材(21)の動きを案内する前に、第1の傾き領域(30A)が外側部材(21)の動きを案内し、
第1の傾き領域(30A)が動きを案内し、外側部材(21)が角度Aだけ回転するとき、外側部材(21)が第1の距離だけハウジング(11)から離れるように軸方向に変位し、
第2の傾き領域(30B)が動きを案内し、外側部材(21)が角度Aだけ回転すると
き、外側部材(21)が第2の距離だけハウジング(11)から離れるように軸方向に変位するように、第1の傾き領域(30A)と第2の傾き領域(30B)とは互いに調整されており、
第2の距離は第1の距離より短く、
機械的インターフェースは、少なくとも1つの相互作用機能を含み、該相互作用機能は、案内トラック(30)と機械的に協働する、前記組立体。 - 第1の傾き領域(30A)の全体を通るための、たとえば組立体の長手方向軸を中心とした、外側部材(21)の回転運動は、第1の傾き領域(30A)の角度範囲αを画成し、
第2の傾き領域(30B)の全体を通るための、たとえば組立体の長手方向軸を中心とした、外側部材(21)の回転運動は、第2の傾き領域(30B)の角度範囲βを画成し、
角度範囲αは、角度範囲βより小さい、請求項1に記載の組立体。 - 角度Aは、角度範囲α以下であり、かつ/または0.5α以上である、請求項2に記載の組立体。
- 第1の傾き領域(30A)は、第2の傾き領域(30B)よりも急である、請求項1~3のいずれか1項に記載の組立体。
- 案内トラック(30)は、第3の傾き領域(30C)を有しており、
組立体がキャップ装着状態からキャップ脱離状態に切り替えられるときに、第3の傾き領域(30C)は、第2の傾き領域(30B)の後に外側部材(21)の動きを案内し、
第3の傾き領域(30C)が動きを案内し、外側部材(21)が角度Aだけ回転するとき、外側部材(21)は第3の距離だけハウジング(11)から離れるように軸方向に変位するように、第1の傾き領域(30A)、第2の傾き領域(30B)、および第3の傾き領域(30C)は互いに調整されており、
第2の距離は第3の距離より短い、請求項2に依存するとき請求項1~4のいずれか1項に記載の組立体。 - 第3の傾き領域30Cの全体を通るための、たとえば組立体の長手方向軸を中心とした、外側部材(21)の回転運動は、第3の傾き領域(30C)に関連した角度範囲γを画成し、
角度範囲γは、角度範囲βより小さく、かつ/または角度範囲αより大きい、請求項5に記載の組立体。 - 第3の傾き領域(30C)は、第2の傾き領域(30B)よりも急である、請求項5または6に記載の組立体。
- 第2の傾き領域(30B)における案内トラック(30)の傾きは一定である、請求項1~7のいずれか1項に記載の組立体。
- 第1の傾き領域(30A)における案内トラック(30)の傾きは一定である、請求項1~8のいずれか1項に記載の組立体。
- キャップ(12)は、内側部材(24)を含み、ハウジングユニットは、放出開口部を有するリザーバを含み、
該リザーバにはシールド(1)が取外し可能に接続されており、
キャップ(12)がハウジング(11)に接続されているとき、内側部材(24)はシ
ールド(1)に接続されており、それによりキャップ(12)がハウジング(11)から取り外されるとき、内側部材(24)はリザーバからシールド(1)を取り外す、請求項1~9のいずれか1項に記載の組立体。 - リザーバに対してシールド(1)を軸方向に動かすのに必要な力は、リザーバからのシールド(1)の取外し中に変化し、力は、リザーバからシールド(1)が取り外されている間に生じる最大値を有しており、ハウジング(11)からのキャップ(12)の取外し中に第2の傾き領域(30B)によって画成される動きの範囲内に最大値が含まれるように、案内トラック(30)は構成されている、請求項10に記載の組立体。
- シールド(1)は、剛性の外側区域(2B)と弾性の内側区域(2A)とを含み、
該剛性の外側区域(2B)は、内側部材(24)に面しており、該弾性の内側区域(2A)は、リザーバの放出開口部に面している、請求項10または11に記載の組立体。 - 案内トラック(30)は、キャップ(12)の一部分に配置されている、請求項1~12のいずれか1項に記載の組立体。
- 組立体は自動注射器である、請求項1~13のいずれか1項に記載の組立体。
- キャップ(12)は、中間部材(27)を含み、外側部材(21)と該中間部材(27)との間に機械的インターフェースが確立され、ここで:
-相互作用機能が、外側部材(21)に位置付けられ、案内トラック(30)が、該中間部材(27)に位置付けられる;または
-相互作用機能が、該中間部材(27)に位置付けられ、案内トラック(30)が、外側部材(21)に位置付けられる、
請求項1~14のいずれか1項に記載の組立体。 - キャップ(12)は、中間部材(27)を含み、該キャップ(12)が、該中間部材(27)を介してハウジング(11)に接続される、請求項1~15のいずれか1項に記載の組立体。
- 中間部材(27)とハウジング(11)との間の接続は、シールド(1)を軸方向に動かすのに必要な最大力よりも小さい解放するための力を必要とする、請求項16に記載の組立体。
- 請求項1~17のいずれか1項に記載の組立体と、薬物とを含む、薬物送達デバイス。
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EP2926860B1 (en) * | 2012-03-14 | 2018-12-26 | SHL Medical AG | Medicament delivery device |
ES2722002T3 (es) * | 2015-06-15 | 2019-08-06 | Gerresheimer Regensburg Gmbh | Dispositivo de seguridad para una jeringa |
TW201726194A (zh) * | 2015-11-27 | 2017-08-01 | 賽諾菲阿凡提斯德意志有限公司 | 用於移除帽蓋的系統(二) |
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WO2017089259A1 (en) * | 2015-11-27 | 2017-06-01 | Sanofi-Aventis Deutschland Gmbh | An injection device |
CN108367124A (zh) | 2015-11-27 | 2018-08-03 | 赛诺菲-安万特德国有限公司 | 注射装置 |
TW201731547A (zh) * | 2015-11-27 | 2017-09-16 | 賽諾菲阿凡提斯德意志有限公司 | 注射裝置(七) |
EP3351279A1 (en) * | 2017-01-20 | 2018-07-25 | Sanofi-Aventis Deutschland GmbH | Drug delivery device |
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US20140371684A1 (en) | 2011-12-06 | 2014-12-18 | Shl Group | Injection Device |
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