JP7334218B2 - Method for Providing Double-Sided Printed Information on Combination Tablets Using Pharmaceutical Packaging Boxes - Google Patents

Description

Application of Article 30, Paragraph 2 of the Patent Act (1) Publication date: Multiple days during the period from September 15, 2015 to November 27, 2015 Publication location: Toho Pharmaceutical Co., Ltd. (Marunouchi, Chiyoda-ku, Tokyo) 1-9-2 Gran Tokyo South Tower 12F), Kyushu Toho Co., Ltd. (3-4-46 Hakozaki Futo, Higashi-ku, Fukuoka City, Fukuoka Prefecture) (see Attachment 1) (2) Date: November 21, 2015 Sunday (Saturday) to 23 (Monday) Venue: Inside the exhibition booth at the 25th Annual Meeting of the Japanese Society of Pharmaceutical Health Care and Sciences Pacifico Yokohama (1-1-1 Minatomirai, Nishi-ku, Yokohama-shi, Kanagawa) (3) Website publication date: November 25, 2015 Website address: http://www. ohara-ch. co. jp/staff/info_change/index. html

The present invention relates to a packaging box for pharmaceutical products with an improved method of providing pharmaceutical information. In the packaging box for pharmaceutical products of the present invention, the information printed on both sides of the tablet can be visually recognized without the need to open the box and take out the tablet product inside.

Packaging boxes for pharmaceutical products are packed with tablets enclosed in PTP sheets, powders, injections, eye drops, and the like, and are provided to medical sites such as pharmacies. On the surface of the packaging box of pharmaceutical products, various pharmaceutical information such as the name of the drug, drug content in the formulation, medical use, etc. It is now common practice to describe

At present, attempts to write drug information are not limited to packaging boxes, but are also being made to the tablets themselves. The method of writing drug information on the tablet itself is generally known to have the advantage of preventing medical malpractice by medical professionals such as pharmacists and preventing accidental ingestion by patients. The information described on the tablet itself includes the common name of the medicinal ingredient or its abbreviation, the content, the name of the manufacturing and sales company, and the like. The act of printing characters on tablets has become more widely practiced as it has become possible in recent years to print clear characters on tablets using laser light or inkjet. However, tablets with characters printed thereon do not account for a sufficiently high percentage of all tablet products, and further efforts are needed to popularize them.

There are two types of tablets: single drugs containing a single active ingredient and combination tablets containing two or more active ingredients (combination tablets). Medical information is also printed on combination tablets. Attempts are being made. Since a compound tablet contains two or more medicinal ingredients, naturally more information about drugs should be written on the tablet than a single tablet containing a single medicinal ingredient. Therefore, in combination tablets, it becomes very necessary to use both sides of the tablet in order to include a lot of necessary information.
However, in general, the tablets contained in the packaging box are packaged to ensure the stability of the contained medicinal ingredients against light, humidity, etc., and the visibility of the packaged tablets is very low. bad for For example, many tablets are enclosed in a PTP sheet, and in this state, even if one side of the tablet can be visually recognized, it is difficult to visually recognize both sides. Therefore, at present, it is not always desirable to have different information printed on both sides of the tablet, because it is difficult for pharmacists to recognize the information and to explain when the tablet is handed over to the patient. Therefore, the current situation is that it is not very positive to try to print different information on both sides of a compound tablet.
Therefore, in order to widely promote the convenience of having different information printed on both sides of a compound tablet, the present inventors have developed a method that allows easy visual confirmation of information printed on both sides of the compound tablet even in the packaged state. aimed at the development of

Design registration No. 3196225

The problem to be solved by the present invention is to create an excellent method for visually confirming pharmaceutical information printed on both sides of a packaged compound tablet.

The present inventors have made intensive studies in order to solve the above problems, and have found that by placing images of both sides of the compound tablet on the surface of the packaging box of the medicine, the tablet can be packaged without opening the packaging box of the medicine. The inventors have found that each information printed on both sides of a compound tablet can be easily confirmed, and have completed the present invention.

That is, the present invention relates to a pharmaceutical packaging box in which different information is displayed on each of the front surface (synonymous with upper surface) and the back surface (synonymous with lower surface) of a certain tablet, or a method for providing pharmaceutical information using the same. and preferred embodiments thereof are described in (1) to (5) below.
(1) A pharmaceutical packaging box in which images of the front and back sides of the combination tablet housed inside the box are partially described.
(2) On the surface of the compound tablet contained in the box, there is a character string indicating the compounding ingredients or its abbreviation, excluding the character string indicating the dosage form, content, and company name from the character string used as the brand name. The pharmaceutical packaging box according to (1) above, wherein the generic name or abbreviated name of each of the two or more medicinal ingredients contained in the combination tablet is printed on the back surface of the combination tablet.
(3) A character string “combination tablet” is printed on the surface of the combination tablet housed inside the box, and the content of each of the two or more active ingredients is indicated in units of mg or μg on the back surface of the combination tablet. The pharmaceutical packaging box according to (2) above, on which numbers are printed.
(4) The pharmaceutical packaging box according to any one of (1) to (3) above, wherein the images on the front and back sides of the combination tablet are photographs or drawings.
(5) Combination tablets containing valsartan and amlodipine besilate, azilsartan and amlodipine besilate, candesartan and amlodipine besilate, candesartan and hydrochlorothiazide, irbesartan and amlodipine besilate, olmesartan medoxomil and azelnidipine, valsartan and hydrochlorothiazide, clopidogrel The drug according to any one of the above (1) to (4), which contains any two active ingredients of sulfate and aspirin, telmisartan and amlodipine, telmisartan and hydrochlorothiazide, tramadol and acetaminophen, losartan potassium and hydrochlorothiazide. packaging box.

By placing the images of both sides of the combination tablet on the surface of the packaging box of the drug according to the present invention, each information printed on both sides of the combination tablet can be visually recognized in the packaged state, and both sides of the tablet can be viewed by pharmacists, patients, etc. It became possible to easily transmit information printed on In the packaging box of the present invention, the information printed on both sides of the tablet can be confirmed even after the tablet product is no longer at hand as long as there is the packaging box. has the effect of being available more independently as a tool for

FIG. 1 is an example of the surface of a developed view of a packaging box for pharmaceutical products to which the present invention is applied. The dotted lines in the figure represent the parts processed so that the flap can be easily separated. FIG. 2 is an example of a perspective view of a molded and closed packaging box for pharmaceutical products to which the present invention is applied. FIG. 3 is an example of a display method of the images on both sides of the tablet written on the packaging box. FIG. 4 is an example of the surface of a combination tablet. Dotted circles can be replaced with arbitrary character strings indicating compounding ingredients, sales companies, and the like. FIG. 5 is an example of the back side of a combination tablet. Dotted circles can be replaced with arbitrary character strings indicating the generic name, content, etc. of each of two or more medicinal ingredients.

Hereinafter, a pharmaceutical packaging box in which different information is displayed on each of the front and back sides of a tablet according to the present invention or a method for providing pharmaceutical information using the same will be described in detail. However, the following description is an example for explaining the present invention, and is not intended to limit the technical scope of the present invention only to the scope of this description.

<Medicine packaging box according to the present invention>
The pharmaceutical packaging box according to the present invention is preferably made of paper, and a part of the packaging box has images on both the front and back sides of the tablet. Both sides of the tablet can be printed by either a method of printing directly on the packaging box material or a method of attaching a printed article (such as a sticker) to the pharmaceutical packaging box material. The images on both sides of the tablet are selected from a photograph of the actual tablet, a drawing, or the like.
As a part of the packaging box in which both sides of the tablet are described, the surface part of the packaging box that can be visually observed from the outside when unopened (in FIG. 1, any part of 3, 6, 8, 9, 10, 12 ), more preferably the body portion (any portion of 3, 6, 9, or 12 in FIG. 1). The back portion is the opposite side of the front portion. The body portion (parts 1, 3, 6, 9, 12 in FIGS. 1 and 2) is the portion that becomes a flap when the packaging box is formed (2, 4, 5 in FIGS. 1 and 2). , 7, 8, 10, 11 and 13), and the flaps are arranged on both sides of the vertical sides of the body portion. A molded packaging box for pharmaceutical products (Fig. 2) is provided to medical sites.
It is desirable that the packaging box has a size that is easy to store in the medical field. The size of the molded and closed packaging box is preferably 10 cm to 20 cm long and 3 cm to 8 cm wide, more preferably 11 cm to 17 cm long and 4 cm to 7 cm wide.

<Information on both sides of tablet according to the present invention>
Examples of the form of the tablet according to the present invention include round tablets and odd-shaped tablets, with round tablets being preferred. The characters printed on the tablet according to the present invention are preferably on the front side and the back side, and preferably different character information is printed on the front side and the back side. A tablet has surfaces such as a front surface, a back surface, and a side surface, and the front surface and the back surface have surfaces opened toward opposite sides. In the present specification, "surface" means "one side of the tablet treated as the surface", and "back surface" means "one side opposite to the one side of the tablet treated as the surface". It is a term and does not necessarily mean that one side of the tablet has the properties of the front side or the back side. Therefore, whether the same single side of the same tablet is treated as the front side or the back side can be arbitrarily determined according to individual cases.
The tablet according to the present invention is preferably a compound tablet containing two or more active ingredients, which tends to increase the amount of medical information to be printed. On the surface of the compound tablet according to the present invention, there is a character string or a character string substantially indicating the medicinal ingredient compounded in the tablet, excluding the character string indicating the dosage form, content, and company name from the character string of the brand name. An abbreviation (preferably an abbreviation of a character string substantially indicating the medicinal ingredient) is printed. The abbreviation according to the present invention is preferably a name commonly used among medical professionals. Further, it is preferable for the consumer who checks the tablet information that the character string of the combination tablet is printed on the surface of the combination tablet.
On the back side of the compound tablet according to the present invention, the common name or abbreviation thereof for each of the two or more active pharmaceutical ingredients contained in the compound tablet is printed, and the content of each of the two or more active pharmaceutical ingredients in units of mg or μg. is preferably printed.

<Specific example of combination tablet according to the present invention>
Specific examples of the combination tablet according to the present invention include valsartan and amlodipine besylate, azilsartan and amlodipine besylate, candesartan and amlodipine besylate, candesartan and hydrochlorothiazide, irbesartan and amlodipine besylate, olmesartan medoxomil and azelnidipine, Combination tablets containing any of valsartan and hydrochlorothiazide, clopidogrel sulfate and aspirin, telmisartan and amlodipine, telmisartan and hydrochlorothiazide, tramadol and acetaminophen, amlodipine besilate and atorvastatin calcium hydrate, losartan potassium and hydrochlorothiazide However, combination tablets containing valsartan and amlodipine besilate are particularly preferred.
For combination tablets, a brand name that includes a short abbreviation is officially adopted as the official brand name rather than a brand name that includes a long name that uses a combination of the generic names of each of the two or more medicinal ingredients contained. is common. Examples of combinations of long names and short abbreviations in the preamble are “amlodipine besilate/valsartan”/“amvalo”, “candesartan cilexetil/amlodipine besilate”/“camsia”, “telmisartan/amlodipine”/“teramlo”. , "telmisartan/hydrochlorothiazide"/"tertia", "valsartan/hydrochlorothiazide"/"barhidio", "amlodipine besilate/atorvastatin calcium hydrate"/"amarouette", "losartan potassium/hydrochlorothiazide"/"losarhyd", " candesartan/hydrochlorothiazide”/“cadetia”, “irbesartan/amlodipine besilate”/“iruamix” and the like.
When abbreviations used as brand names are printed on combination tablets, it is difficult to predict the generic name of each drug from the abbreviations with certainty, so these generic names must also be printed on the tablet. The generic name according to the present invention is preferably a Japanese translation of the international generic name.

<Packaging form of tablet according to the present invention>
The packaging form of the tablet according to the present invention is preferably aluminum blister packaging or PTP packaging. Furthermore, it is preferable to package with an aluminum pillow as needed.

According to the present invention, it is possible to easily visually confirm the information printed on both sides of the tablet without opening the packaging box and the package enclosing the tablet, and different information is printed on both sides of the tablet. Further active development and provision to the medical field of compound tablets with Moreover, even after the tablets are no longer at hand, the packaging box itself can be used as a tool for transmitting the information printed on both sides of the tablets.

1: Side plate (surface), 2: Canopy flap (surface), 3: Side plate (surface), 4: Canopy flap (surface), 5: Inner flap (surface), 6: Side plate (surface), 7: Inner flap ( surface), 8: canopy flap (surface), 9: side plate (surface), 10: canopy flap (surface), 11: inner flap (surface), 12: side plate (surface), 13: inner flap (surface)

Claims (3)

Images of the front and back sides of the combination tablet housed inside the box are printed on the front side of the packaging box that can be viewed from the outside when the package is unopened, and the images display different drug information on the front and back sides of the combination tablet. This is an image of a combination tablet that is packed inside the box, and on the surface of the combination tablet housed inside the box are the following: (2) a character string indicating the combination tablet, and (3) a character string indicating the name of the sales company are printed on the back of the combination tablet. is printed with (1) a generic name or an abbreviation thereof for each of two or more active pharmaceutical ingredients contained in the combination tablet, and (2) a number indicating the content of each active pharmaceutical ingredient in units of mg or μg; Pharmaceutical packaging box. 2. The pharmaceutical packaging box according to claim 1 , wherein the images on the front and back sides of the combination tablet are photographs or drawings. Combination tablets containing valsartan and amlodipine besilate, azilsartan and amlodipine besilate, candesartan and amlodipine besylate, candesartan and hydrochlorothiazide, irbesartan and amlodipine besilate, olmesartan medoxomil and azelnidipine, valsartan and hydrochlorothiazide, clopidogrel sulfate and 3. The pharmaceutical packaging box according to claim 1 or 2 , comprising any two medicinal ingredients of aspirin, telmisartan and amlodipine, telmisartan and hydrochlorothiazide, tramadol and acetaminophen, losartan potassium and hydrochlorothiazide.