JP7321480B2 - Composition - Google Patents

Description

The present invention relates to a composition comprising a processed green leaf product and a processed starch product.

Conventionally, compositions containing processed green leaf products are known as health foods such as green juice. Due to recent changes in health consciousness and eating habits, the importance of ingesting vegetables has attracted attention, and compositions containing processed green leaves are known as one of the means for easily ingesting a certain amount of vegetables. (For example, Patent Document 1).

Japanese Patent Application Laid-Open No. 2014-155437

On the other hand, the needs of consumers for health foods, including compositions containing processed green leaf products, have diversified in recent years, and the demand for further functions, especially new functions from the viewpoint of health maintenance, is getting stronger. It's becoming
However, conventional compositions containing green leaf processed products have not sufficiently met this demand.

Therefore, the present inventors have made intensive studies on a composition containing a processed green leaf product that can further strengthen the effect on health maintenance. As a result, surprisingly, a composition containing a processed starch product in addition to a processed green leaf product and having a flushing property within a specific range not only has an excellent effect in improving nutritional status or anti-obesity. , and found that both of them are satisfied at the same time, and have completed the present invention.

The present invention is based on the above findings, and provides an oral composition containing a processed green leaf product and a processed starch product, the composition having a degree of dispersion of 30% or more and 70% or less. . However, the degree of dispersion was determined by fixing the bottom surface of a cylindrical container having an inner diameter of 10.44 mm and having a slide shutter below so that the bottom surface was 85 cm above the horizontal surface, and in this state, 2 g of the composition contained in the container was added. It is measured by allowing it to fall naturally, and at this time, on the lid of a Petri dish with an outer diameter of 97.55 mm and a height of 18.10 mm placed with the opening facing downward on the horizontal surface directly below the cylindrical container. It is represented by the following formula from the mass xg of the recovered powder.
Dispersion = x/2 x 100 (%).

ADVANTAGE OF THE INVENTION According to this invention, the composition which not only is excellent in a nutritional status improvement or an anti-obesity effect but satisfies both can be provided simultaneously.

FIG. 1 is a schematic diagram illustrating a method for measuring the degree of dispersion.

The composition of the present invention will be described below based on its preferred embodiments. The composition of this embodiment is an oral composition.
The composition of this embodiment contains a green leaf processed product. The green leaves in the green leaf processed product are not particularly limited as long as they are green plant leaves suitable for food and drink applications. Poaceae plants such as sorghum and sugar cane; Asteraceae plants such as mugwort; Umbelliferae plants such as Angelica keiskei, parsley, celery, and Peucedanum japonicum; Moraceae plants such as mulberry; Labiatae plants such as; Komatsuna, kale, cabbage, cruciferous plants such as broccoli; Liliaceae plants such as asparagus; are barley such as two-rowed barley, six-rowed barley, and naked barley, mugwort, angelica keiskei, botan bofu, mulberry, kale, and sweet potato that can be used as food materials such as green juice. As the green leaves, one or a combination of two or more of these can be used. Green leaves may include not only the leaf portion of the plant body, but also the stem and other portions along with the leaves.

In the case of barley, the green leaves are preferably harvested before maturity, ie from the beginning of tillering to the beginning of heading.

Green leaves are preferably processed immediately after harvesting. If it takes longer to process, it is stored by means of storage commonly used by those skilled in the art, such as cold storage, to prevent deterioration of the green leaves.

In the composition of the present embodiment, as the green leaves, various processed products obtained from the green leaves can be used. Examples of such processed products include dry powder of green leaves, shredded green leaves and dry powder thereof, juice of green leaves and dry powder thereof, extract of green leaves and dry powder thereof, and the like.

For example, a conventionally known method can be used to dry-powder green leaves. As such a method, a method combining drying treatment and pulverization treatment can be used for green leaves. Either the drying treatment or the pulverizing treatment may be performed first, but the drying treatment is preferably performed first. For dry powderization, this method may be combined with one or more treatments selected from blanching treatment, sterilization treatment, and the like, if necessary. Further, the pulverizing treatment may be performed once, or two or more treatments may be combined, but it is preferable to perform a coarse pulverizing treatment followed by a fine pulverizing treatment for finer pulverizing.

The blanching treatment is a treatment for keeping green leaves bright green, and methods of the blanching treatment include hot water treatment, steaming treatment, and the like. In the blanching treatment, green leaves are preferably treated in hot water or steam at 80 to 100° C., preferably 90 to 100° C., for 60 to 180 seconds, preferably 90 to 120 seconds. In addition, when hot water treatment is performed as blanching treatment, by dissolving a carbonate such as magnesium carbonate or a hydrogen carbonate such as sodium hydrogen carbonate in the hot water, the green color of the green leaves can be made more vivid. preferred because it can be done. The steaming treatment is preferably an intermittent steaming treatment in which green leaves are repeatedly steamed with steam and cooled under normal pressure or pressure. In the intermittent steaming treatment, the steaming treatment is preferably performed for 20 to 40 seconds, more preferably 30 seconds. The cooling treatment after the steaming treatment is preferably performed immediately, and the method is not particularly limited, but can be immersion in cold water, refrigeration, cooling with cold air, evaporative cooling with hot air, or evaporative cooling with a combination of hot air and cold air. etc. are used. Among these, evaporative cooling in which hot air and cold air are combined is preferable. Such cooling treatment is carried out so that the product temperature of green leaves is preferably 60° C. or lower, more preferably 50° C. or lower, and most preferably 40° C. or lower. In order to produce a green leaf powder rich in nutrients such as vitamins, minerals and chlorophyll, it is preferable to repeat the intermittent steaming treatment 2 to 5 times.

A sterilization treatment is usually a treatment for physically and chemically killing microbial cells using temperature, pressure, electromagnetic waves, chemicals, and the like. If the blanching treatment is performed in addition to the drying treatment and the pulverizing treatment, the blanching treatment is preferably performed before the drying treatment. Moreover, when sterilization treatment is performed in addition to the drying treatment and the pulverization treatment, the sterilization treatment is preferably performed after the drying treatment or before or after the pulverization treatment.

As the drying treatment, it is preferable to dry the green leaves so that the water content of the green leaves is 10% by mass or less, particularly 5% by mass or less. This drying treatment can be performed by any method known to those skilled in the art, such as hot air drying, high-pressure steam drying, electromagnetic wave drying, and freeze drying. Drying by heating can be carried out preferably at 40° C. to 140° C., more preferably at 80° C. to 130° C., at a temperature and for a time at which the green leaves are not discolored by heating.

The pulverization treatment includes pulverization by any method commonly used by those skilled in the art using a crusher, a mill, a blender, a stone mill, or the like. The crushed green leaves are sieved as needed.

As a specific dry powdering method, for example, barley green leaves are cut, blanched, then dried to a moisture content of 10% by mass or less, preferably 5% by mass or less, and then dried. A method of pulverizing can be mentioned (see JP-A-2004-000210). Further, for example, a method of cutting green leaves, performing branching treatment, then kneading, then drying and pulverizing (see Japanese Patent Application Laid-Open No. 2002-065204 and Japanese Patent No. 3428956) can also be used. Another example is a method in which green leaves are dried, coarsely pulverized, heated at 110° C. or higher, and then finely pulverized (see Japanese Patent Application Laid-Open No. 2003-033151 and Japanese Patent No. 3277181).

As a method for dividing green leaves into small pieces, methods such as slicing, crushing, shredding, and the like, which are commonly used by those skilled in the art to divide a plant body into small pieces, can be used. As an example of comminution, it may be slurried. Slurrying is carried out by subjecting the green barley leaves to a mixer, juicer, blender, masscolloider, or the like to make the green barley leaves thick and porridge-like (liquid-solid suspension). By slurrying in this way, the green leaves preferably have an average diameter of 1 mm or less, more preferably 0.5 mm or less, still more preferably 0.1 mm or less, and most preferably 0.05 mm. It is shredded into small pieces and becomes fluid.

Examples of the method for squeezing the green leaves include squeezing the green leaves or their shredded material, or centrifuging or filtering the shredded green leaves of barley. A typical example is a method of squeezing by mechanical crushing means such as a mixer or juicer, and optionally removing coarse solids by means of sieving, filtration or the like to obtain a squeezed liquid. . Specifically, methods described in JP-A-08-245408, JP-A-09-047252, JP-A-5-7471, JP-A-4-341153, etc., and these known methods can be appropriately selected and implemented by those skilled in the art.

A method for obtaining a green leaf extract includes adding an extraction solvent commonly used by those skilled in the art, such as ethanol, water, and hydrous ethanol, to a green leaf or a fragment thereof, and extracting by stirring or heating as necessary. be able to. The extract may be concentrated if desired.

Among processed products of green leaves, it is particularly preferable to use green leaf dry powder (also referred to as pulverized powder) because it is easier to obtain the effect of improving nutritional status and anti-obesity.

The processed green leaf product is preferably a powder that can pass through any sieve having a particle size of 30 to 250 mesh, because this facilitates uniform mixing of the green leaf powder and the processed starch product. From the same point of view, it is more preferable that 90% by mass or more of the green leaf powder pass through 200 mesh.

From the viewpoint of further enhancing the effects of improving nutrition and anti-obesity, the content of the processed green leaf in the solid content of the composition is preferably 0.1% by mass or more, and 0.5% by mass or more in terms of dry mass. It is more preferably 1% by mass or more, particularly preferably 3% by mass or more, particularly preferably 5% by mass or more, and most preferably 10% by mass or more. From the same viewpoint, the upper limit is preferably 99.9% by mass or less, more preferably 99% by mass or less, still more preferably 97% by mass or less, particularly preferably 90% by mass or less, and particularly preferably 75% by mass or less. Preferably, 50% by mass or less is most preferable.

The composition contains a starch product. The processed starch product is preferably a decomposition product obtained by enzymatic decomposition or acid decomposition of starch or a reduced product thereof. Examples of enzymes used herein include amylase and glucoamylase, and examples of acids include mineral acids such as hydrochloric acid. The starch of processed starch products includes various plant-derived starches such as corn, waxy corn, potato, sweet potato, tapioca, sago, wheat, rice, and glutinous rice. The processed starch is a polymer of α-glucose, and its binding mode is typically α1-4 glycosidic bond, α1-6 glycosidic bond, α1-3 glycosidic bond, α1-2 glycosidic bond. may contain Preferred processed starch products are small sugars (oligosaccharides) or polysaccharides in which two or more α-glucoses are linked via glycosidic bonds, or reduced forms thereof. Dextrin, calcined dextrin, and other starch derivatives. The processed starch product that can be used as an excipient is particularly preferable. For example, as a small sugar, maltose (maltose), maltotriose, maltotetraose, etc., can be mentioned as sugars in which 2 or more and 20 or less α-glucoses are linked. Sugar alcohols include maltitol (reduced maltose), maltotriitol and the like as reduced forms of these small sugars; Dextrin includes maltodextrin, acrodextrin, erythrodextrin and amylodextrin; Examples thereof include those obtained by heating starch to about 110 to 200 ° C. with or without the addition of a mineral acid such as hydrochloric acid; If necessary, those obtained by performing purification treatments such as gluco α-amylase treatment and ion exchange resin chromatography treatment, such as "Pine Fiber" (registered trademark) (manufactured by Matsutani Chemical Industry Co., Ltd.), "Fibersol" (manufactured by Matsutani Chemical Industry Co., Ltd.) and the like; and examples of the starch derivatives include oxidized starch, etherified starch, phosphate esterified starch and the like . The processed starch can be used alone or in combination of two or more of these. In particular, the processed starch is preferably at least one selected from indigestible dextrin, maltose, and maltitol. Moreover, it is preferable that the processed starch product is in the form of powder.

Another feature of the composition of the present embodiment is that it contains a processed green leaf product and a processed starch product, and has a specific degree of dispersion. As a result of intensive studies on the relationship between the structure of the composition containing the processed green leaf material and its functionality, the present inventor found that the jetting property (flushing property) when containing the processed starch product is within a specific range. It was found that not only the nutritional improvement effect in the case of undernutrition and the anti-obesity effect in the case of high nutrition are excellent, but also both are satisfied at the same time.
In the present embodiment, this jetting property (flushing property) is measured as a degree of dispersion according to the following method. A method for measuring the degree of dispersion will be described with reference to FIG.

As shown in FIG. 1, the cylindrical container 21a is fixed using a stand and a clamp so that the lower end of the container 21a is 85 cm above the horizontal surface 24. As shown in FIG. The cylindrical container 21 a is fixed so that its center axis direction X is perpendicular to the horizontal plane 24 . The cylindrical container 21a has an inner diameter of 10.44 mm, and its end face is formed on a plane perpendicular to the central axis direction X of the cylinder. The outer diameter of the cylindrical container 21a is 14.06 mm, and the thickness of the cylindrical container 21a is substantially constant. The cylindrical container 21a has a plate-shaped slide shutter 21b below it. The slide shutter 21b is capable of opening and closing the lower opening of the cylindrical container 21a, and in the closed state shown in FIG. This prevents the composition in the container 21a from falling.

As shown in FIG. 1, a petri dish lid 22 is placed below the cylindrical container 21a. The lid 22 of the petri dish is cylindrical with a bottom, and has a height of 18.10 mm and an outer diameter of 97.55 mm. The petri dish lid 22 is placed on a horizontal plane 24 directly below the cylindrical container 21a so that the center of the circular lid surface passes through the extension of the central axis X of the cylindrical container 21a, with the opening facing downward ( That is, it is installed so that the circular cover surface faces upward).

As shown in FIG. 1, in the above state, 2 g of specimen 20 is accommodated in cylindrical container 21a. After that, by sliding the slide shutter 21b, the sample 20 is naturally dropped onto the horizontal surface 24. As shown in FIG. Let x be the mass of the sample that fell on the lid of the petri dish, and the degree of dispersion is calculated by the following formula.
Dispersion = x/2 x 100 (%)

The degree of dispersion is the average value of 10 measurements by the above method. The humidity (RH) is preferably 10% or more and 70% or less, and the temperature is preferably 1°C or more and 30°C or less. The degree of dispersion is measured indoors, preferably under the condition of a wind speed of 1 m/s or less.

When the composition is powdery, it can be directly used for the measurement of the degree of dispersion. However, when the water content of the powder is 30% by mass or more, it is dried at 30 ° C to 50 ° C in a state of humidity (RH) of 40% to 60% to reduce the water content to less than 30% by mass. It is preferred to measure the dispersity.
It is preferable that 95% by mass or more of the powder pass through a 30-mesh sieve, for example.

On the other hand, the composition may be in a solid form that does not pass through 30 mesh, such as granules, tablets, rods, plates, blocks, solids, rounds, candy, tablets, gummies, wafers, biscuits, etc. In the case of cookie-like, cake-like, chewable, syrup-like, stick-like, etc., it is pulverized into a powder that can pass through 30 mesh, and then, when the above moisture content is satisfied, it is subjected to a dispersity test. is preferred. Examples of the pulverization treatment in this case include dry pulverization, and as a specific dry pulverization method, pulverization using a hammer mill, a roll mill, a ball mill, a jet mill, or the like is preferable.

On the other hand, when the composition is in a form other than solid, such as syrup, liquid, gel, jelly, paste, or cream, the above-described drying treatment is performed to reduce the water content to the above upper limit or less. If necessary, it is preferably subjected to the same dry pulverization as described above to obtain a powder that can pass through 30 mesh, and then subjected to a dispersity test. Examples of the drying treatment in this case include spray drying and freeze drying to a moisture content of 1% by mass or less.

When the composition is in the form of a capsule such as a hard capsule or a soft capsule, or in the form of a caplet, the contents taken out of the capsule are optionally subjected to the drying treatment and/or pulverization treatment as described above to obtain a degree of dispersion. It is preferable to use it for measurement.

In this embodiment, when the degree of dispersion is 30% or more and 70% or less, both effects of improving nutritional status and anti-obesity can be obtained. From the viewpoint of enhancing both actions, the degree of dispersion is preferably 35% or more and 65% or less, more preferably 40% or more and 60% or less.

A composition having a degree of dispersion within the above range can be obtained by adjusting the type and amount of processed starch. The types of starch products are as described above. In addition, the amount of processed starch in the composition is preferably 0.1% by mass or more and 99.9% by mass or less, and 1% by mass or more and 97% by mass or less as a dry mass in the solid content of the composition. More preferably, it is more preferably 3% by mass or more and 90% by mass or less, even more preferably 5% by mass or more and 75% by mass or less, and 10% by mass or more and 50% by mass or less. Especially preferred.

The composition of the present embodiment may contain other components in addition to the green leaf processed product and the starch processed product. Examples of the other ingredients include vitamins, proteins, oligosaccharides, minerals, dairy products, processed plant products, microorganisms such as lactic acid bacteria, sugars, sweeteners, citric acid, acidulants, coloring agents, and brightening agents. In addition, manufacturing agents such as talc, silicon dioxide, cellulose, calcium stearate, and the like can be blended. Other ingredients include various excipients, binders, lubricants, stabilizers, diluents, bulking agents, emulsifiers, coloring agents, flavors, food additives, seasonings, etc. can be done. The content of other components can be appropriately selected according to the form of the composition and the like. In the present embodiment, the content of components other than the processed green leaf material and processed starch contained in the composition is preferably 99% by mass or less, particularly preferably 97% by mass or less, in the solid content.

The composition of this embodiment can be in the various forms described above. In addition, the composition of the present embodiment is preferably used as an eating and drinking composition such as green juice and smoothies, and particularly preferably used as an eating and drinking composition for green juice. The food and drink composition for green juice is a beverage containing green leaves as various processed products. are mentioned. In particular, when the composition is in the form of a powder or granules, and the mixture with water is orally ingested, it is suitable for long-term storage to prevent spoilage, and when this composition for food and drink is mixed with water, the color changes. is preferred because it is vivid. When the composition is in a solid form, as described above, it can be mixed with water to form a liquid, and the liquid can be taken orally, such as by drinking. Depending on the situation, it may be taken orally as a solid. In addition to water, it may be used by adding it to milk, soy milk, fruit juice drinks, whey drinks, soft drinks, yogurt, hot cake mix, and the like. Needless to say, it may also be used as a supplement, health food, food with nutrient function claims, food with function claims, food for specified health uses, and pharmaceuticals.

As described in the examples below, the composition of the present embodiment contains a processed green leaf product and a processed starch product and satisfies the degree of dispersion in the range described above. can. Specifically, by orally ingesting the composition of the present embodiment under low nutritional conditions such as low protein and low calcium, the amount of protein and calcium in the blood can be maintained or increased. conditions and malnutrition conditions such as low calcium conditions are improved. In addition, weight reduction can be suppressed by orally ingesting the composition of the present embodiment under low nutritional conditions such as low protein and low calcium. In addition, in a satiety state or a state of overnutrition, orally ingesting the composition of the present embodiment can suppress weight gain and prevent or reduce obesity. Therefore, by ingesting the composition of the present embodiment, it is possible to suppress weight gain and loss associated with malnutrition or overnutrition due to disordered eating habits, and is effective in physical condition management and health maintenance. For example, by orally ingesting the composition of the present embodiment, it is possible to prevent and improve malnutrition such as senility, unbalanced diet, and hypoproteinemia and hypocalcemia associated with extreme diets. It is possible to easily limit the weight while maintaining the In particular, the elderly are prone to hypoproteinemia and hypocalcemia due to loss of appetite, reduced food intake, unbalanced diet, etc., and the composition of the present embodiment can be used to suppress or improve such symptoms. can. Furthermore, in the past, when people restricted their eating habits by dieting and ingested health foods in a state of malnutrition, the malnutrition was not improved. However, according to the composition of the present embodiment, it is possible to achieve both improvement of nutritional status and prevention or improvement of obesity, making it easier to diet while maintaining health. In addition, since the composition of the present invention has both effects of improving nutritional status and preventing or improving obesity, it can be taken in a sufficient amount even on a diet, and green leaves can be expected to improve the lack of vegetables. The composition of the present embodiment is used for one or more uses selected from anti-obesity, nutritional improvement, prevention or improvement of hypoproteinemia, prevention or improvement of hypocalcemia, and improvement of lack of vegetables. be able to.

EXAMPLES The present invention will be described in more detail below with reference to Examples, but the scope of the present invention is not limited to these Examples.

[Examples 1 to 5 and Comparative Examples 1 to 6]
As the processed green leaf product, the dried barley green leaf powder produced in Production Example 1 below was used. Indigestible dextrin, maltose or maltitol was used as the processed starch. All of these starch processed products were powdery.
As a sample of Comparative Example 1, dry powder of green leaves was used.
A mixture containing dry green leaf powder and indigestible dextrin was used as samples for Comparative Examples 2 and 3 and Examples 1 to 3, and a mixture containing dry green leaf powder and maltitol was used as a sample for Example 4. A mixture containing dried green leaf powder and maltose was used as a sample of Example 5. Furthermore, as a sample of Comparative Example 4, indigestible dextrin was used. As a sample of Comparative Example 5, maltitol was used. As a sample of Comparative Example 6, maltose was used. The compositions of Examples 1 to 5 and Comparative Examples 1 to 6 are all powdery, pass through a 30-mesh sieve and do not pass through a 250-mesh sieve, and the moisture content measured by the above method is It was less than 30% by mass. The mixture of green leaf dry powder and processed starch (indigestible dextrin, maltitol or maltose) in the compositions of Comparative Examples 2 and 3 and Examples 1 to 5 had the degree of dispersion measured by the above method as shown in Table 1 below. The ratio was set as a value. The degree of dispersion was measured under the conditions of room temperature (1 to 30° C.), humidity (RH) of 10 to 70%, and wind speed of 1 m/s.

(Production example 1)
As a raw material, green leaves containing barley stalks cut before heading were used. This was washed with water to remove adhering mud, etc., and cut into pieces of about 5 to 10 cm in size for pretreatment. The pretreated green leaves were blanched only once in hot water at 90-100° C. for 90-120 seconds and then cooled in cold water. Subsequently, the obtained green leaves were dried with hot air at 80° C. to 130° C. in a dryer for 20 minutes to 180 minutes until the water content became 5% by mass or less. The dried green leaves were coarsely pulverized to a size of about 1 mm. The obtained barley green leaves were pulverized so that 90% by mass or more passed through a 200-mesh section to obtain a dry powder sample of the green leaves. In the green leaf powder sample, 90% by mass or more passed through 200 mesh.

The powdery samples of Examples 1-5 and Comparative Examples 1-6 were subjected to Animal Test 1 below.
[Animal test 1: Weight gain and loss in a satiation state]
Male KK-Ay mice (21- to 25-week-old) were acclimatized for 2 days or longer, weighed on day 0 of the test, and divided into 12 groups. The 12 groups were a control group and a group that received the compositions of Examples 1-5 and Comparative Examples 1-6. During the acclimatization period, MF powder feed (manufactured by Oriental Yeast Co., Ltd.) was given ad libitum. For 3 days from day 0 of the test, the control group was given MF powder feed, and the other 9 groups were each given a mixture of 3% by mass of the corresponding composition (test substance) and 97% by mass of MF powder feed. . The body weight was measured again in the afternoon of the 3rd day of the test, and Δg1 = body weight on the 3rd day of the test - body weight on the 0th day of the test. Table 1 shows the results. In addition, based on the weight fluctuation g1, those evaluated as highly effective in suppressing weight gain are indicated by ◎, those evaluated as moderately high in inhibiting weight gain are indicated by 〇, and those evaluated as being low in weight gain are indicated by ×. 1.

As shown in Table 1, the composition of each example containing a green leaf processed product and a starch processed product and having a dispersion degree of 30% or more and 70% or less does not contain either the green leaf processed product or the starch processed product. Or, compared to the compositions of Comparative Examples 1 to 6, which contain both and have a degree of dispersion outside the scope of the present invention, when ingested under satiety conditions without nutritional restriction, it is excellent in suppressing weight gain. rice field.

Further, the powdery samples of Examples 1-5 and Comparative Examples 1-6 were subjected to Animal Test 2 below.
[Animal study 2: body weight change, blood protein concentration, Ca concentration under malnutrition]
Male C57BL/6J(DIO) mice (11 to 14 weeks old) were given the same acclimation period as above for 2 days or more, then weighed on day 0 of the test, and divided into 10 groups. The 10 groups were a control group and a group that received the compositions of Examples 1-5 and Comparative Examples 1-6. For 3 days from day 0 of the test, the control group was given a test feed (low-protein diet) having the composition shown in Table 2 below, and the other 9 groups each had a corresponding composition (test substance) of 3.5% by mass and the above A mixture of 96.5% by mass of the test feed was ingested. The body weight was measured in the afternoon of the 3rd day of the test, and Δg2 = body weight on the 3rd day of the test - body weight on the 0th day of the test. In addition, blood was collected from the tail vein, serum was collected, and protein concentration in serum and calcium concentration in serum were measured using commercially available kits. These results are shown in Table 3.
In Table 3, based on the body weight change g2, ⊚ indicates that the effect of suppressing weight loss is high, ◯ indicates that it is slightly high, and x indicates that it is low.
In addition, based on the serum protein concentration, ⊚ indicates that the serum protein reduction inhibitory effect is high, ◯ indicates that it is slightly high, and × indicates that it is low.
In addition, based on the serum Ca concentration, ⊚ indicates that the serum Ca reduction inhibitory effect is high, ◯ indicates that it is slightly high, and x indicates that it is low.
Table 3 shows again the constituent components and the degree of dispersion of the powdery compositions of Examples and Comparative Examples shown in Table 1.

As shown in Table 3, the composition of each example was superior to the composition of each comparative example in suppressing weight loss when ingested under low-protein diet conditions. In addition, the composition of each example had higher serum protein levels and serum calcium levels under low-protein diet conditions than the compositions of each comparative example.

From the above, it can be seen that the composition of the present invention is excellent in both nutritional status improvement and anti-obesity actions.

Specimen 20
Cylindrical container 21a
Slide shutter 21b
Petri dish lid 22

Claims (2)

An oral composition containing dry barley green leaf powder and processed starch, having a dispersity of 30% or more and 70% or less, passing through a 30-mesh sieve and not passing through a 250-mesh sieve. A powdery composition, wherein the processed starch is at least one selected from indigestible dextrin, maltose, and maltitol, and is used for anti-obesity, improving nutrition , suppressing weight loss, and treating hypoproteinemia. A composition for preventing or improving disease, or for preventing or improving hypocalcemia (except for health foods containing soybeans or their extracts and brown sugar, powdered food materials containing dietary fiber) When granulating, excluding foods containing dietary fiber that are granulated by adding xylooligosaccharide to the food material before or during the granulation process, and excluding those containing guava leaf extract and maltitol.) .
However, the degree of dispersion is the powder of the composition that has a water content of less than 30% by mass and passes through a 30-mesh sieve but does not pass through a 250-mesh sieve under the conditions of room temperature, humidity of 10 to 70%, and wind speed of 1 m/s. about,
A cylindrical container with an inner diameter of 10.44 mm having a slide shutter below is fixed at a height of 85 cm from the horizontal surface,
In this state, 2 g of the composition powder contained in the container is allowed to fall freely, and
At this time, on the horizontal plane directly below the cylindrical container,
From the mass x of the powder collected on the lid of a petri dish with an outer diameter of 97.55 mm and a height of 18.10 mm placed with the opening facing downward,
It is represented by the following formula.
Dispersion = x/2 x 100 (%). 2. The composition according to claim 1 , which is the following (1) or (2).
(1) Used for suppressing weight loss, preventing or improving hypoproteinemia, or preventing or improving hypocalcemia when ingested under low-protein diet conditions.
(2) anti-obesity and
Any one selected from improving nutrition under malnutrition, suppressing weight loss when taken under low-protein diet conditions, preventing or improving hypoproteinemia, and preventing or improving hypocalcemia. It is used for compatibility with the above.

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