JP7254350B2 - β-1,6-グルカン治療用抗体コンジュゲート - Google Patents
β-1,6-グルカン治療用抗体コンジュゲート Download PDFInfo
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- JP7254350B2 JP7254350B2 JP2019531127A JP2019531127A JP7254350B2 JP 7254350 B2 JP7254350 B2 JP 7254350B2 JP 2019531127 A JP2019531127 A JP 2019531127A JP 2019531127 A JP2019531127 A JP 2019531127A JP 7254350 B2 JP7254350 B2 JP 7254350B2
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| US11865135B2 (en) | 2016-12-07 | 2024-01-09 | Innate Biotherapeutics, Llc | ß-1,6-glucan therapeutic antibody conjugates |
| CN113512116B (zh) * | 2020-04-10 | 2022-09-20 | 苏州普乐康医药科技有限公司 | 一种抗igf-1r抗体及其应用 |
| JP2024539993A (ja) * | 2021-10-29 | 2024-10-31 | ボルト バイオセラピューティクス、インコーポレーテッド | システイン変異抗体を含むtlrアゴニスト免疫複合体、及びその使用 |
| CA3243636A1 (en) * | 2022-02-28 | 2023-08-31 | Tridem Bioscience Gmbh & Co Kg | CONJUGATED COMPRISING AT LEAST ONE β-GLUCANE OR ONE MANNANA |
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| WO2016118654A1 (en) | 2015-01-20 | 2016-07-28 | Immunexcite, Inc. | Compositions and methods for cancer immunotherapy |
| WO2016196682A1 (en) | 2015-06-01 | 2016-12-08 | Immunexcite, Inc. | β-1,6-GLUCAN CETUXIMAB ANTIBODY CONJUGATES |
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| AU2003295326A1 (en) | 2002-09-04 | 2004-04-23 | Cancer therapy using beta glucan and antibodies | |
| US8048432B2 (en) * | 2003-08-06 | 2011-11-01 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Polysaccharide-protein conjugate vaccines |
| US7070778B2 (en) | 2003-10-30 | 2006-07-04 | Laboratoire Goemar Sa | Therapeutical combination against cancer |
| FR2944448B1 (fr) | 2008-12-23 | 2012-01-13 | Adocia | Composition pharmaceutique stable comprenant au moins un anticorps monodonal et au moins un polysacharide amphiphile comprenant des substituants derives d'alcools hydrofobes ou d'amines hydrophobes. |
| WO2011011617A1 (en) | 2009-07-22 | 2011-01-27 | Biothera, Inc. | Therapeutic compositions and methods |
| WO2012154818A1 (en) * | 2011-05-09 | 2012-11-15 | Biothera, Inc. | B-glucan compounds, compositions, and methods |
| AU2014214751B2 (en) * | 2013-02-08 | 2017-06-01 | Novartis Ag | Specific sites for modifying antibodies to make immunoconjugates |
| JP2017515898A (ja) | 2014-05-08 | 2017-06-15 | イミューンエクサイト, インコーポレイテッド | 免疫調節β−1,6−D−グルカン |
| US11865135B2 (en) | 2016-12-07 | 2024-01-09 | Innate Biotherapeutics, Llc | ß-1,6-glucan therapeutic antibody conjugates |
| JP2019536811A (ja) | 2016-12-07 | 2019-12-19 | イネイト バイオセラピューティクス, エルエルシー | β−1,6−グルカンのトラスツズマブ抗体コンジュゲート |
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| JP2011519049A (ja) | 2008-04-29 | 2011-06-30 | イミューンエクサイト インコーポレイテッド | 免疫調節組成物およびその使用方法 |
| WO2016118654A1 (en) | 2015-01-20 | 2016-07-28 | Immunexcite, Inc. | Compositions and methods for cancer immunotherapy |
| WO2016196682A1 (en) | 2015-06-01 | 2016-12-08 | Immunexcite, Inc. | β-1,6-GLUCAN CETUXIMAB ANTIBODY CONJUGATES |
Non-Patent Citations (3)
| Title |
|---|
| Cancer Res. (2015) vol.75, no.15, suppl.1, Abstract 4297,<https://cancerres.aacrjournals.org/content/75/15_Supplement/4297> |
| J. Immunother. Cancer (2014) vol.2, suppl.3, P262 |
| J. Immunother. Cancer (2015) vol.3, suppl.2, P414 |
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| WO2018106645A1 (en) | 2018-06-14 |
| EP3582810A4 (en) | 2020-08-19 |
| EP3582810A1 (en) | 2019-12-25 |
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| US11865135B2 (en) | 2024-01-09 |
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