JP7237835B2 - 低強度集束超音波脈動（ｌｉｆｕｐ）デバイスを使用する変性認知症の処置 - Google Patents

低強度集束超音波脈動（ｌｉｆｕｐ）デバイスを使用する変性認知症の処置 Download PDF

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JP7237835B2
JP7237835B2 JP2019532946A JP2019532946A JP7237835B2 JP 7237835 B2 JP7237835 B2 JP 7237835B2 JP 2019532946 A JP2019532946 A JP 2019532946A JP 2019532946 A JP2019532946 A JP 2019532946A JP 7237835 B2 JP7237835 B2 JP 7237835B2
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ultrasound
transducer
pulse
pulses
brain
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JP2020501734A (ja
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シェリー ジョーダン，
マーク エバン シェーファー，
アレックス コーブ，
ウォルター ウィリアム ウースター，
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ブレインソニックス コーポレイション
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N2007/0004—Applications of ultrasound therapy
    • A61N2007/0021—Neural system treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N2007/0004—Applications of ultrasound therapy
    • A61N2007/0021—Neural system treatment
    • A61N2007/0026—Stimulation of nerve tissue

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
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JP2019532946A 2016-12-15 2017-12-14 低強度集束超音波脈動（ｌｉｆｕｐ）デバイスを使用する変性認知症の処置 Active JP7237835B2 (ja)

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JP2022019312A JP2022062218A (ja) 2016-12-15 2022-02-10 低強度集束超音波脈動（ｌｉｆｕｐ）デバイスを使用する変性認知症の処置

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US201662434744P 2016-12-15 2016-12-15
US62/434,744 2016-12-15
PCT/US2017/066532 WO2018112269A1 (en) 2016-12-15 2017-12-14 Treating degenerative dementia using low intensity focused ultrasound pulsation (lifup) device

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JP2020501734A JP2020501734A (ja) 2020-01-23
JP2020501734A5 JP2020501734A5 (https=) 2021-01-28
JP7237835B2 true JP7237835B2 (ja) 2023-03-13

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JP2022019312A Withdrawn JP2022062218A (ja) 2016-12-15 2022-02-10 低強度集束超音波脈動（ｌｉｆｕｐ）デバイスを使用する変性認知症の処置

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EP (1) EP3554636B1 (https=)
JP (2) JP7237835B2 (https=)
AU (1) AU2017378419A1 (https=)
CA (1) CA3046335A1 (https=)
ES (1) ES2896128T3 (https=)
IL (1) IL267307A (https=)
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Families Citing this family (12)

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Publication number Priority date Publication date Assignee Title
US10974078B2 (en) 2012-12-27 2021-04-13 Brainsonix Corporation Treating degenerative dementia with low intensity focused ultrasound pulsation (LIFUP) device
US9061133B2 (en) 2012-12-27 2015-06-23 Brainsonix Corporation Focused ultrasonic transducer navigation system
US10512794B2 (en) 2016-12-16 2019-12-24 Brainsonix Corporation Stereotactic frame
WO2020210813A1 (en) * 2019-04-11 2020-10-15 The General Hospital Corporation Generating imaging-based neurological state biomarkers and estimating cerebrospinal fluid (csf) dynamics based on coupled neural and csf oscillations during sleep
CN110507917A (zh) * 2019-07-30 2019-11-29 哈尔滨医科大学 一种超高场磁共振引导的低强度聚焦超声爆破系统
CN110975176B (zh) * 2019-12-27 2021-04-27 中国人民解放军总医院 一种用于人体脑部磁波刀的自动调控的方法和装置
US11759661B2 (en) 2020-05-20 2023-09-19 Brainsonix Corporation Ultrasonic transducer treatment device
US12257446B2 (en) 2020-08-24 2025-03-25 Brainsonix Corporation Systems and methods for neuromodulation of neuronal circuits using transcranial focused microwave pulses
KR102637479B1 (ko) * 2020-11-18 2024-02-16 주식회사 뉴로소나 저강도 집속 초음파 치료 장치
EP4342394A1 (de) 2022-09-23 2024-03-27 MTS Medical UG Vorrichtung und system zur behandlung von alzheimererkrankungen
WO2025013486A1 (ja) * 2023-07-07 2025-01-16 サウンドウェーブイノベーション株式会社 超音波治療装置
JP2025020754A (ja) * 2023-07-31 2025-02-13 株式会社リコー 生体内液流促進装置

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110270138A1 (en) 2010-05-02 2011-11-03 Mishelevich David J Ultrasound macro-pulse and micro-pulse shapes for neuromodulation
US20120197163A1 (en) 2011-01-27 2012-08-02 Mishelevich David J Patterned control of ultrasound for neuromodulation
US20120296241A1 (en) 2011-05-22 2012-11-22 Mishelevich David J Ultrasound neuromodulation for treatment of autism spectrum disorder and alzheimers disease and other dementias
US20140188011A1 (en) 2012-12-27 2014-07-03 Brainsonix Corporation Focused ultrasonic transducer navigation system
WO2015192189A1 (en) 2014-06-20 2015-12-23 The University Of Queensland Neurodegenerative disease treatment
US20160067526A1 (en) 2014-09-04 2016-03-10 National Yang-Ming University Method for treating and/or preventing neurodegenerative diseases by using low-intensity pulsed ultrasound (LIPUS)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999015903A1 (de) * 1997-09-19 1999-04-01 Evotec Biosystems Ag Verfahren zur messung der assoziation von teilstrukturen pathologischer proteinablagerungen
US20050020945A1 (en) * 2002-07-02 2005-01-27 Tosaya Carol A. Acoustically-aided cerebrospinal-fluid manipulation for neurodegenerative disease therapy
US20140186423A1 (en) * 2012-03-27 2014-07-03 Mathew Gelfand Transdermal Patch Having Ultrasound Transducer for Administering Thrombolytic Reagents to Patients Having a Protein Misfolding Disease
US20140058293A1 (en) * 2012-05-23 2014-02-27 Sunnybrook Research Institute Multi-Frequency Ultrasound Device and Method of Operation
JP6585836B2 (ja) 2016-05-12 2019-10-02 株式会社日立製作所 エネルギー照射装置

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110270138A1 (en) 2010-05-02 2011-11-03 Mishelevich David J Ultrasound macro-pulse and micro-pulse shapes for neuromodulation
US20120197163A1 (en) 2011-01-27 2012-08-02 Mishelevich David J Patterned control of ultrasound for neuromodulation
US20120296241A1 (en) 2011-05-22 2012-11-22 Mishelevich David J Ultrasound neuromodulation for treatment of autism spectrum disorder and alzheimers disease and other dementias
US20140188011A1 (en) 2012-12-27 2014-07-03 Brainsonix Corporation Focused ultrasonic transducer navigation system
WO2015192189A1 (en) 2014-06-20 2015-12-23 The University Of Queensland Neurodegenerative disease treatment
US20160067526A1 (en) 2014-09-04 2016-03-10 National Yang-Ming University Method for treating and/or preventing neurodegenerative diseases by using low-intensity pulsed ultrasound (LIPUS)

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JORDAO, Jessica F. et al.，"Amyloid-β plaque reduction, endogenous antibody delivery and glial activation by brain-targeted, transcranial focused ultrasound"，Experimental Neurology，(米)，Elsevier Inc.，2013年，Vol. 248，p. 16-29

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WO2018112269A1 (en) 2018-06-21
JP2020501734A (ja) 2020-01-23
EP3554636A4 (en) 2020-08-19
EP3554636A1 (en) 2019-10-23
AU2017378419A1 (en) 2019-07-04
IL267307A (en) 2019-08-29
EP3554636B1 (en) 2021-09-01
ES2896128T3 (es) 2022-02-24
JP2022062218A (ja) 2022-04-19
CA3046335A1 (en) 2018-06-21

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