JP7203015B2 - 免疫原性組成物 - Google Patents

免疫原性組成物 Download PDF

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Publication number
JP7203015B2
JP7203015B2 JP2019511574A JP2019511574A JP7203015B2 JP 7203015 B2 JP7203015 B2 JP 7203015B2 JP 2019511574 A JP2019511574 A JP 2019511574A JP 2019511574 A JP2019511574 A JP 2019511574A JP 7203015 B2 JP7203015 B2 JP 7203015B2
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Japan
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influenza
amino acid
seq
region
vector
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JP2019511574A
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Japanese (ja)
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JP2019534242A (ja
JP2019534242A5 (https=
Inventor
クレイグ トンプソン，
スネトラ グプタ，
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Oxford University Innovation Ltd
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Oxford University Innovation Ltd
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Priority to JP2022209044A priority Critical patent/JP7762643B2/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/275—Poxviridae, e.g. avipoxvirus
    • A61K39/285—Vaccinia virus or variola virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/108—Orthomyxoviridae (F), e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5258—Virus-like particles

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2019511574A 2016-08-25 2017-08-25 免疫原性組成物 Active JP7203015B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022209044A JP7762643B2 (ja) 2016-08-25 2022-12-26 免疫原性組成物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1614485.9A GB201614485D0 (en) 2016-08-25 2016-08-25 Immunogenic composition
GB1614485.9 2016-08-25
PCT/GB2017/052510 WO2018037246A1 (en) 2016-08-25 2017-08-25 Immunogenic composition

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022209044A Division JP7762643B2 (ja) 2016-08-25 2022-12-26 免疫原性組成物

Publications (3)

Publication Number Publication Date
JP2019534242A JP2019534242A (ja) 2019-11-28
JP2019534242A5 JP2019534242A5 (https=) 2020-10-01
JP7203015B2 true JP7203015B2 (ja) 2023-01-12

Family

ID=57119951

Family Applications (2)

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JP2019511574A Active JP7203015B2 (ja) 2016-08-25 2017-08-25 免疫原性組成物
JP2022209044A Active JP7762643B2 (ja) 2016-08-25 2022-12-26 免疫原性組成物

Family Applications After (1)

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JP2022209044A Active JP7762643B2 (ja) 2016-08-25 2022-12-26 免疫原性組成物

Country Status (8)

Country Link
US (2) US11123422B2 (https=)
EP (1) EP3504235A1 (https=)
JP (2) JP7203015B2 (https=)
CN (1) CN109923125B (https=)
AU (3) AU2017315238A1 (https=)
CA (1) CA3034328A1 (https=)
GB (1) GB201614485D0 (https=)
WO (1) WO2018037246A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201614485D0 (en) * 2016-08-25 2016-10-12 Univ Oxford Innovation Ltd Immunogenic composition
WO2020061443A2 (en) * 2018-09-21 2020-03-26 Board Of Regents Of The University Of Nebraska Methods of making and using universal centralized influenza vaccine genes
GB2578163A (en) * 2018-10-19 2020-04-22 Univ Pretoria Plant produced avian influenza antigens and their uses in diagnostic assays and devices
GB202204478D0 (en) * 2022-03-29 2022-05-11 Univ Oxford Innovation Ltd Immunogenic compositions

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235877A (en) 1979-06-27 1980-11-25 Merck & Co., Inc. Liposome particle containing viral or bacterial antigenic subunit
CA2035576A1 (en) 1990-02-07 1991-08-08 Alexander R. Neurath Conformational epitopes of human immunodeficiency virus envelope glycoprotein gp120 hiv-1
AU727602B2 (en) 1995-09-01 2000-12-14 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
AU2003228267A1 (en) * 2002-03-05 2003-09-22 Board Of Regents, The University Of Texas System Methods of enhancing immune induction involving mda-7
AU2006236910B2 (en) * 2005-04-11 2012-06-07 Purdue Research Foundation Vaccine against pandemic strains of influenza viruses
WO2007134327A2 (en) * 2006-05-15 2007-11-22 Sea Lane Biotechnologies, Llc. Neutralizing antibodies to influenza viruses
CN104140958A (zh) * 2006-08-09 2014-11-12 米迪缪尼有限公司 流感血凝素和神经氨酸酶变体
NZ590351A (en) 2008-07-18 2012-11-30 Medicago Inc HA1 domain totally or partially free of N-linked glycosylation operatively linked to a regulatory region
WO2011126370A1 (en) 2010-04-09 2011-10-13 Universiteit Utrecht Holding B.V. Recombinant multimeric influenza proteins
CA2807664A1 (en) * 2010-08-12 2012-02-16 Theraclone Sciences, Inc. Anti-hemagglutinin antibody compositions and methods of use thereof
US8883171B2 (en) 2010-09-14 2014-11-11 University of Pittsburgh—of the Commonwealth System of Higher Education Computationally optimized broadly reactive antigens for influenza
WO2012089231A1 (en) 2010-12-30 2012-07-05 Okairòs Ag Paramyxovirus vaccines
CN104582714A (zh) * 2012-05-23 2015-04-29 斯坦福大学托管董事会 流感疫苗构建体
US8932598B2 (en) * 2012-08-28 2015-01-13 Vaxinnate Corporation Fusion proteins and methods of use
ES2803508T3 (es) 2013-03-28 2021-01-27 Medicago Inc Producción de partículas similares al virus de la gripe en plantas
GB201614485D0 (en) * 2016-08-25 2016-10-12 Univ Oxford Innovation Ltd Immunogenic composition

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Journal of Virology，2012年，Vol. 86, No. 21，p. 11686-11697
Journal of Virology，2014年，Vol. 88, No. 12，p. 6743-6750
Journal of Virology，2014年，Vol. 88, No. 13，p. 7130-7144

Also Published As

Publication number Publication date
WO2018037246A4 (en) 2018-04-19
US20190201521A1 (en) 2019-07-04
AU2026200025A1 (en) 2026-01-22
JP2019534242A (ja) 2019-11-28
JP2023052092A (ja) 2023-04-11
US20220054625A1 (en) 2022-02-24
GB201614485D0 (en) 2016-10-12
AU2017315238A1 (en) 2019-02-21
CN109923125A (zh) 2019-06-21
WO2018037246A1 (en) 2018-03-01
US11123422B2 (en) 2021-09-21
EP3504235A1 (en) 2019-07-03
AU2024227680A1 (en) 2024-11-21
JP7762643B2 (ja) 2025-10-30
US12390518B2 (en) 2025-08-19
CA3034328A1 (en) 2018-03-01
CN109923125B (zh) 2024-05-31

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