JP7164200B2 - サッカライド－ポリペプチドコンジュゲートの組成物およびその使用の方法 - Google Patents

サッカライド－ポリペプチドコンジュゲートの組成物およびその使用の方法 Download PDF

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JP7164200B2
JP7164200B2 JP2019502538A JP2019502538A JP7164200B2 JP 7164200 B2 JP7164200 B2 JP 7164200B2 JP 2019502538 A JP2019502538 A JP 2019502538A JP 2019502538 A JP2019502538 A JP 2019502538A JP 7164200 B2 JP7164200 B2 JP 7164200B2
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serotypes
polypeptide
pharmaceutical composition
saccharide
serotype
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JP2019513821A5 (enExample
JP2019513821A (ja
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ブルース ディー． フォレスト，
ジャック ディー． ラブ，
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ポゴナ， エルエルシー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2019502538A 2016-03-31 2017-03-31 サッカライド－ポリペプチドコンジュゲートの組成物およびその使用の方法 Active JP7164200B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2022111088A JP2022130741A (ja) 2016-03-31 2022-07-11 サッカライド－ポリペプチドコンジュゲートの組成物およびその使用の方法
JP2023152185A JP2023166591A (ja) 2016-03-31 2023-09-20 サッカライド－ポリペプチドコンジュゲートの組成物およびその使用の方法
JP2025095460A JP2025124888A (ja) 2016-03-31 2025-06-09 サッカライド－ポリペプチドコンジュゲートの組成物およびその使用の方法

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201662316555P 2016-03-31 2016-03-31
US62/316,555 2016-03-31
US201662330245P 2016-05-02 2016-05-02
US62/330,245 2016-05-02
US201662372263P 2016-08-08 2016-08-08
US62/372,263 2016-08-08
US201662373807P 2016-08-11 2016-08-11
US62/373,807 2016-08-11
PCT/US2017/025621 WO2017173415A2 (en) 2016-03-31 2017-03-31 Saccharide-polypeptide conjugate compositions and methods of use thereof

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JP2022111088A Division JP2022130741A (ja) 2016-03-31 2022-07-11 サッカライド－ポリペプチドコンジュゲートの組成物およびその使用の方法

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JP2019513821A JP2019513821A (ja) 2019-05-30
JP2019513821A5 JP2019513821A5 (enExample) 2020-05-14
JP7164200B2 true JP7164200B2 (ja) 2022-11-01

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JP2019502538A Active JP7164200B2 (ja) 2016-03-31 2017-03-31 サッカライド－ポリペプチドコンジュゲートの組成物およびその使用の方法
JP2022111088A Revoked JP2022130741A (ja) 2016-03-31 2022-07-11 サッカライド－ポリペプチドコンジュゲートの組成物およびその使用の方法
JP2023152185A Pending JP2023166591A (ja) 2016-03-31 2023-09-20 サッカライド－ポリペプチドコンジュゲートの組成物およびその使用の方法
JP2025095460A Pending JP2025124888A (ja) 2016-03-31 2025-06-09 サッカライド－ポリペプチドコンジュゲートの組成物およびその使用の方法

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JP2022111088A Revoked JP2022130741A (ja) 2016-03-31 2022-07-11 サッカライド－ポリペプチドコンジュゲートの組成物およびその使用の方法
JP2023152185A Pending JP2023166591A (ja) 2016-03-31 2023-09-20 サッカライド－ポリペプチドコンジュゲートの組成物およびその使用の方法
JP2025095460A Pending JP2025124888A (ja) 2016-03-31 2025-06-09 サッカライド－ポリペプチドコンジュゲートの組成物およびその使用の方法

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US (2) US11058757B2 (enExample)
EP (2) EP4488286A3 (enExample)
JP (4) JP7164200B2 (enExample)
WO (1) WO2017173415A2 (enExample)

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Publication number Publication date
JP2025124888A (ja) 2025-08-26
US11058757B2 (en) 2021-07-13
EP3436061A4 (en) 2019-12-04
US20200113993A1 (en) 2020-04-16
JP2023166591A (ja) 2023-11-21
EP4488286A2 (en) 2025-01-08
WO2017173415A2 (en) 2017-10-05
JP2022130741A (ja) 2022-09-06
US20220143167A1 (en) 2022-05-12
WO2017173415A3 (en) 2017-11-09
JP2019513821A (ja) 2019-05-30
EP4488286A3 (en) 2025-04-02
EP3436061A2 (en) 2019-02-06

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