JP7105456B1 - A food for improving poor physical condition that improves vitality, suppresses depression, and recovers from fatigue - Google Patents

A food for improving poor physical condition that improves vitality, suppresses depression, and recovers from fatigue Download PDF

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JP7105456B1
JP7105456B1 JP2021006203A JP2021006203A JP7105456B1 JP 7105456 B1 JP7105456 B1 JP 7105456B1 JP 2021006203 A JP2021006203 A JP 2021006203A JP 2021006203 A JP2021006203 A JP 2021006203A JP 7105456 B1 JP7105456 B1 JP 7105456B1
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JP2022112035A (en
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健太郎 二宮
直樹 猪狩
秀樹 片野
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Daiwa Pharmaceutical Co Ltd
Venex Co Ltd
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Abstract

【課題】活力の低下や、認知機能の低下などの体調不良が改善できるようにする。【解決手段】第1工程S101で、乾燥したホタテガイの外套膜より、窒素雰囲気下でエタノール抽出した抽出液を得る。次に、第2工程S102で、得られた抽出液を濃縮して濃縮液を得る。次に、第3工程S103で、濃縮液にオリーブオイルなどの食用油およびビタミンEなどの酸化防止剤を加えて調整する。ここでは、濃縮液にオリーブオイルおよびビタミンEを加えて、プラズマローゲン含有率が1%以上となる状態に調整する。【選択図】 図1[PROBLEMS] To improve poor physical condition such as decreased vitality and decreased cognitive function. Kind Code: A1 In a first step S101, an extract is obtained by extracting ethanol from a dried scallop mantle in a nitrogen atmosphere. Next, in a second step S102, the obtained extract is concentrated to obtain a concentrate. Next, in a third step S103, an edible oil such as olive oil and an antioxidant such as vitamin E are added to the concentrate for adjustment. Here, olive oil and vitamin E are added to the concentrate to adjust the plasmalogen content to 1% or more. [Selection diagram] Fig. 1

Description

本発明は、活力の向上や、集中力の向上などのための活力を向上しふさぎこみを抑制し疲労回復させる体調不良改善食品に関する。 TECHNICAL FIELD The present invention relates to a poor physical condition improving food that improves vitality and vitality for improving concentration, suppresses depression, and recovers from fatigue.

世界の総人口に占める65歳以上の者の割合(高齢化率)は、1950年の5.1%から2015年には8.3%に上昇している。さらに2060年には、高齢化率が17.8%にまで上昇するものと見込まれており、今後高齢化が急速に進展することになる。このような中で、近年、シニア世代を含む55歳以上の高齢者における活力の低下への対応が注目を集めている。加齢により、例えば、心身の活力(運動機能や認知機能など)が低下し、心理的な不安、体の痛みなどが出現する。また、加齢による社会技能の低下により生活機能が傷害され、心身の脆弱性が出現する。 The proportion of people aged 65 and over to the total population of the world (aging rate) has risen from 5.1% in 1950 to 8.3% in 2015. Furthermore, the aging rate is expected to rise to 17.8% in 2060, and aging will progress rapidly in the future. Under such circumstances, in recent years, attention has been focused on how to deal with the decrease in vitality of the elderly aged 55 and over, including seniors. With aging, for example, mental and physical vitality (motor function, cognitive function, etc.) decreases, and psychological anxiety, body pain, and the like appear. In addition, deterioration of social skills due to aging impairs life functions, and physical and mental vulnerability emerges.

上述した身体的な機能、認知機能などの体調不良は、高齢者に限るものではなく、改善対象の重要点として注目されている。活力などが低下する体調不良の要因は多様であるが、例えば年齢を重ねることで体力や気力が低下し、疲労が溜まりやすくなり、その回復時間が増加することは、誰にでも起こり得る。これらのことは、人に次の活動・行動の開始を躊躇させる。 Poor physical condition such as physical function and cognitive function mentioned above is not limited to elderly people, and is attracting attention as an important point to be improved. There are various factors that cause poor physical condition, such as a decrease in vitality. For example, as we age, physical strength and energy decrease, fatigue easily accumulates, and recovery time increases. These things make people hesitate to start the next activity/behavior.

また、これらのことが積み重なることで、筋力などの身体機能も低下し、身体の痛みの発症や社会技能の低下を招き、結果として活動量や食欲が低下する。活動量や食欲の低下は、さらなる活力の低下を生むという負のスパイラルを招きかねない。また、心身が徐々に弱体化し精神的な健康状態が低下すると、自信の喪失や外部との接触を低下させる要因となる。これらのことも、認知機能の低下、筋力の低下、活力の低下、食欲の低下、集中力の低下などを招き、こちらも負のスパイラルに陥ることがある。 In addition, by accumulating these factors, physical functions such as muscle strength decline, leading to the onset of physical pain and a decline in social skills, resulting in a decrease in the amount of activity and appetite. A decrease in activity level and appetite can lead to a negative spiral that creates a further decrease in vitality. In addition, the gradual weakening of the mind and body and the decline in mental health can lead to a loss of self-confidence and reduced contact with the outside world. These can also lead to a decline in cognitive function, a decline in muscle strength, a decline in vitality, a decline in appetite, a decline in concentration, etc., which can also fall into a negative spiral.

上述したように、現代の生活においては、活力の低下や、認知機能の低下などの体調不良を抑制することが、重要視されている。 As described above, in modern life, it is important to suppress poor physical condition such as a decrease in vitality and a decrease in cognitive function.

本発明は、以上のような問題点を解消するためになされたものであり、活力の低下や、認知機能の低下などの体調不良が改善できるようにすることを目的とする。 SUMMARY OF THE INVENTION The present invention has been made to solve the problems described above, and an object of the present invention is to improve poor physical condition such as decreased vitality and decreased cognitive function.

本発明に係る体調不良改善食品は、乾燥したホタテガイの外套膜より、窒素雰囲気下でエタノール抽出した抽出液を得る第1工程と、抽出液を濃縮して濃縮液を得る第2工程と、濃縮液に食用油および酸化防止剤を加えて調整する第3工程とにより生成し、体調不良改善に用いられる。 The food for improving poor physical condition according to the present invention includes a first step of obtaining an extract by ethanol extraction from a dried scallop mantle under a nitrogen atmosphere, a second step of concentrating the extract to obtain a concentrate, and a concentration. It is produced by the third step of adding edible oil and antioxidant to the liquid and used to improve poor physical condition.

上記体調不良改善食品の一構成例において、抽出液には、プラズマローゲンが含まれ、第3工程は、プラズマローゲン含有率が1%以上となる範囲で調整する。 In one structural example of the food for improving poor physical condition, the extract contains plasmalogen, and in the third step, the plasmalogen content is adjusted within a range of 1% or more.

上記体調不良改善食品の一構成例において、第1工程は、酸素を含まない雰囲気で実施する。 In one structural example of the food for improving poor physical condition, the first step is performed in an oxygen-free atmosphere.

上記体調不良改善食品の一構成例において、第1工程は、窒素雰囲気下で実施する。 In one structural example of the food for improving poor physical condition, the first step is performed under a nitrogen atmosphere.

以上説明したように、本発明によれば、乾燥したホタテガイの外套膜より、窒素雰囲気下でエタノール抽出した抽出液を濃縮した濃縮液に、食用油および酸化防止剤を加えて調整したので、体調不良改善食品を経口摂取することで、活力の低下や、認知機能の低下などの体調不良が改善できる。 As described above, according to the present invention, the extract obtained by extracting the dried scallop mantle with ethanol under a nitrogen atmosphere is concentrated, and the edible oil and the antioxidant are added to the concentrated solution, so that the physical condition is improved. Oral ingestion of food for improving poor physical condition can improve poor physical condition such as decreased vitality and decreased cognitive function.

図1は、本発明の実施の形態に係る体調不良改善食品の作製方法について説明するフローチャートである。FIG. 1 is a flow chart illustrating a method for preparing food for improving poor physical condition according to an embodiment of the present invention. 図2は、POMS2の結果について示す特性図である。FIG. 2 is a characteristic diagram showing the result of POMS2. 図3は、POMS2のVAの結果について示す特性図である。FIG. 3 is a characteristic diagram showing the result of VA of POMS2. 図4は、追加した15の設問に対する結果について示す特性図である。FIG. 4 is a characteristic diagram showing the results for the 15 additional questions. 図5は、追加設問1(頭が重い、身体が重い)の結果を示す特性図である。FIG. 5 is a characteristic diagram showing the results of additional question 1 (heavy head, heavy body). 図6は、追加設問2(人の名前が思い出せない等の物忘れが多い)の結果を示す特性図である。FIG. 6 is a characteristic diagram showing the results of additional question 2 (frequent forgetfulness, such as being unable to remember people's names). 図7は、追加設問3(集中力が持続しない、たりない)の結果を示す特性図である。FIG. 7 is a characteristic diagram showing the results of additional question 3 (cannot maintain concentration). 図8は、追加設問7(目が疲れる、目がかすむ、見えづらい)の結果を示す特性図である。FIG. 8 is a characteristic diagram showing the results of additional question 7 (eye fatigue, blurred vision, difficulty in seeing). 図9は、追加設問9(夜眠れない、寝つきが悪い)の結果を示す特性図である。FIG. 9 is a characteristic diagram showing the results of additional question 9 (I can't sleep at night, I have trouble falling asleep). 図10は、追加設問13(便秘気味だ)の結果を示す特性図である。FIG. 10 is a characteristic diagram showing the results of additional question 13 (I feel constipated).

以下、本発明の実施の形態に係る体調不良改善食品について説明する。まず、体調不良改善食品の作製方法について、図1を参照して説明する。 A food for improving poor physical condition according to an embodiment of the present invention will be described below. First, a method for preparing food for improving poor physical condition will be described with reference to FIG.

まず、第1工程S101で、乾燥したホタテガイの外套膜よりエタノール抽出した抽出液を得る。例えば、乾燥したホタテガイの外套膜90kgを、液温を20~60℃程度とした濃度95%のエタノール約100~2000kgに混合し、1~5時間撹拌する。この抽出処理は、例えば、窒素雰囲気下など、酸素が含まれない雰囲気で実施することができる。この後、エタノールよりホタテガイの外套膜を取り出し(分離し)、第1抽出液とする。次いで、取り出したホタテガイの外套膜を、再度、液温を20~60℃程度とした濃度95%のエタノール約100~2000kgに混合し、1~5時間撹拌する。この抽出処理も、例えば、窒素雰囲気下など、酸素が含まれない雰囲気で実施することができる。この後、エタノールよりホタテガイの外套膜を取り出し(分離し)、第2抽出液とする。得られた第1抽出液と第2抽出液とを混合し、この混合液を濾過することで、抽出液とする。 First, in the first step S101, an extract is obtained by ethanol extraction from the dried scallop mantle. For example, 90 kg of dried scallop mantle is mixed with about 100 to 2000 kg of 95% ethanol at a liquid temperature of about 20 to 60° C. and stirred for 1 to 5 hours. This extraction treatment can be carried out in an oxygen-free atmosphere such as, for example, a nitrogen atmosphere. Thereafter, the scallop mantle is taken out (separated) from the ethanol to obtain a first extract. Next, the mantle of the scallop taken out is again mixed with about 100 to 2000 kg of ethanol having a concentration of 95% at a liquid temperature of about 20 to 60° C. and stirred for 1 to 5 hours. This extraction treatment can also be performed in an oxygen-free atmosphere such as, for example, a nitrogen atmosphere. Thereafter, the scallop mantle is taken out (separated) from the ethanol to obtain a second extract. The obtained first extract and second extract are mixed, and the mixture is filtered to obtain an extract.

次に、第2工程S102で、得られた抽出液を濃縮して濃縮液を得る。次に、第3工程S103で、濃縮液に食用油および酸化防止剤を加えて調整する。食用油は、例えば、オリーブオイルとすることができる。また、酸化防止剤は、ビタミンEとすることができる。食用油は、オリーブオイルに限らず、大豆油、菜種油、コーンオイルなど植物油や魚油などとすることができ、また、これらを組み合わせて用いることもできる。酸化防止剤は、ビタミンEに限らず、ローズマリー抽出物やチャ抽出物などを用いることができ、またこれらを組み合わせることもできる。ここで抽出液には、プラズマローゲンが含まれており、プラズマローゲン含有率が1%以上となる範囲で、濃縮液に食用油および酸化防止剤を加えて調整する。 Next, in a second step S102, the obtained extract is concentrated to obtain a concentrate. Next, in the third step S103, the concentrate is adjusted by adding edible oil and an antioxidant. The edible oil can be, for example, olive oil. Also, the antioxidant can be vitamin E. The edible oil is not limited to olive oil, but may be vegetable oil such as soybean oil, rapeseed oil, corn oil, or fish oil, or may be used in combination. Antioxidants are not limited to vitamin E, and rosemary extracts, tea extracts, and the like can be used, and these can also be combined. Here, the extract contains plasmalogen, and an edible oil and an antioxidant are added to the concentrated solution to adjust the concentration so that the plasmalogen content is 1% or more.

実施の形態に係る体調不良改善食品は、第1工程において抽出した抽出物を有効成分として含み、体調不良改善に用いるものである。この抽出物には、プラズマローゲンを主とする脂質が含まれていることが分析の結果判明している。この抽出物による体調不良改善食品は、経口摂取により、活気や活力の向上、物忘れの改善、集中力の向上、眼精疲労の改善、睡眠の質の向上、便秘改善など、体調不良改善に用いるものである。実施の形態に係る体調不良改善食品を経口摂取することで、活気や活力の向上、物忘れの改善、集中力の向上、眼精疲労の改善、睡眠の質の向上、便秘改善など、体調不良の改善が可能となるものと考えられる。実施の形態に係る体調不良改善食品は、睡眠の質を向上させるプラズマローゲンを含有するリン脂質素材により、脳神経を亢進し、活力を向上しふさぎこみを抑制して、疲労回復させるものである。 The food for improving poor physical condition according to the embodiment contains the extract extracted in the first step as an active ingredient, and is used for improving poor physical condition. Analysis revealed that this extract contained lipids, mainly plasmalogen. This extract-based food for improving poor physical condition is used orally to improve poor physical condition, such as improvement of liveliness and vitality, improvement of forgetfulness, improvement of concentration, improvement of eye strain, improvement of sleep quality, and improvement of constipation. It is a thing. By orally ingesting the food for improving poor physical condition according to the embodiment, improvement of vitality and vitality, improvement of forgetfulness, improvement of concentration, improvement of asthenopia, improvement of sleep quality, improvement of constipation, etc. It is thought that improvement is possible. The poor physical condition improving food according to the embodiment promotes cranial nerves, improves vitality, suppresses depression, and recovers from fatigue with a phospholipid material containing plasmalogen that improves the quality of sleep.

次に、上述した本実施の形態に係る体調不良改善食品を用いた体調不良改善の効果について、実施例を用いて説明する。 Next, the effect of improving poor physical condition using the food for improving poor physical condition according to the present embodiment described above will be described using examples.

[実施例]
実施例では、実施の形態に係る体調不良改善食品を用いてヒト試験を行った。この試験では、試験内容を説明し同意を得た46名を被験者とした。被験者46名は、平均年齢43.9歳、男20名、女26名である。
[Example]
In Examples, a human test was conducted using the food for improving poor physical condition according to the embodiment. In this test, 46 subjects who explained the contents of the test and obtained consent were used as subjects. The 46 subjects had an average age of 43.9 years, 20 males and 26 females.

ソフトカプセルとした体調不良改善食品を1粒/日で、3ヶ月間摂取した。ソフトカプセルとした体調不良改善食品の1粒には、プラズマローゲン0.5mgが含まれていることが確認されている。 A soft capsule of food for improving poor physical condition was ingested at a dose of 1 tablet/day for 3 months. It has been confirmed that 0.5 mg of plasmalogen is contained in one soft capsule of food for improving poor physical condition.

また、国際的に利用されているPOMS2短縮版(設問数35)を用い、被験者に、気分、感情、情緒などの心理状態について質問してアンケートを採った。また、設問には、POMS2短縮版の設問に加え、14問のあらたな設問を追加設定した。アンケートは、試験開始時、1ヶ月後、2ヶ月後、3ヶ月後、合計4回実施した。 In addition, using the internationally used shortened version of POMS2 (number of questions: 35), the subjects were asked about their psychological states such as mood, emotion, and emotion, and a questionnaire was taken. In addition to the questions in the shortened version of POMS2, 14 new questions were added to the questions. The questionnaire was conducted four times in total, at the beginning of the test, 1 month, 2 months and 3 months later.

POMS2短縮版は、35の設問ごとに「怒り-敵意(AH)」、「混乱-当惑(CB)」、「抑うつ-落ち込み(DD)」、「疲労-無気力(FI)」、「緊張-不安(TA)」、「活気-活力(VA)」、「友好(F)」の7つの尺度に分けられており、さらにそれら因子から「総合的気分状態得点(TMD)」を算出する。AH、CB、DD、FI、TAおよびTMDについては、値が低い方が、心理状態が良好であることを表し、VAとFについては、値が高い方が、心理状態が良好であることを表す。 The shortened version of POMS2 consists of 35 questions with anger-hostility (AH), confusion-bewilderment (CB), depression-depression (DD), fatigue-lethargy (FI), and tension-anxiety. (TA)”, “Vitality-Vitality (VA)”, and “Friendship (F)”, and a “Total Mood State Score (TMD)” is calculated from these factors. For AH, CB, DD, FI, TA, and TMD, a lower value indicates a better psychological state, and for VA and F, a higher value indicates a better mental state. show.

POMSの設問以外に新たに追加した設問は以下の通りである。
1:頭が重い、身体が重い。
2:人の名前が思い出せない等の物忘れが多い。
3:集中力が持続しない、たりない。
4:食欲がない。
5:会話やテレビの音が聞こえにくい。
6:鼻が利く、においに敏感。
7:目が疲れる、目がかすむ、見えづらい。
8:頭の回転・反応速度の向上。
9:夜眠れない、寝つきが悪い。
10:夜中になんども目が覚める。
11:夜中にトイレに起きる。
12:朝寝起きが悪い、つらい。
13:便秘気味だ。
14:よく下痢をする。
The following questions were newly added in addition to the POMS questions.
1: Heavy head, heavy body.
2: Often forgetful, such as being unable to remember people's names.
3: Concentration is not sustained or insufficient.
4: No appetite.
5: It is difficult to hear conversations and TV sounds.
6: Good nose, sensitive to odors.
7: Tired eyes, blurred vision, difficulty in seeing.
8: Improve head rotation and reaction speed.
9: I can't sleep at night, and I have trouble falling asleep.
10: I wake up many times in the middle of the night.
11: I get up to go to the bathroom in the middle of the night.
12: Difficulty waking up in the morning, painful.
13: I feel constipated.
14: I often have diarrhea.

POMS2の結果について図2,図3に示す。開始時との比較で、VA(活気-活力)が1ヶ月後に活気-活力(VA)が有意に上昇した。図2では、各設問に対し、最も左の棒グラフが試験開始時、左から2つめの棒グラフが1ヶ月後、左から3つめの棒グラフが2ヶ月後、最も右の棒グラフが3ヶ月後である。 The results of POMS2 are shown in FIGS. 2 and 3. FIG. Vitality-vitality (VA) increased significantly after 1 month compared to the start time. In Figure 2, for each question, the leftmost bar graph is at the beginning of the test, the second bar graph from the left is after 1 month, the third bar graph from the left is after 2 months, and the rightmost bar graph is after 3 months. .

追加した15の設問について図4に示す。図4において、各設問に対し、最も左の棒グラフが試験開始時、左から2つめの棒グラフが1ヶ月後、左から3つめの棒グラフが2ヶ月後、最も右の棒グラフが3ヶ月後である。開始時との比較で、設問1、2、3、7、9、13に有意差が認められた。 Fig. 4 shows the 15 additional questions. In FIG. 4, for each question, the leftmost bar graph is at the start of the test, the second bar graph from the left is after 1 month, the third bar graph from the left is after 2 months, and the rightmost bar graph is after 3 months. . A significant difference was observed in questions 1, 2, 3, 7, 9, and 13 compared to the start.

追加設問1(頭が重い、身体が重い)のグラフを図5に示す。 Fig. 5 shows the graph of additional question 1 (heavy head, heavy body).

追加設問2(人の名前が思い出せない等の物忘れが多い)のグラフを図6に示す。 FIG. 6 shows a graph of additional question 2 (a lot of forgetfulness, such as being unable to remember people's names).

追加設問3(集中力が持続しない、たりない)のグラフを図7に示す。 Fig. 7 shows the graph for additional question 3 (cannot maintain concentration).

追加設問7(目が疲れる、目がかすむ、見えづらい)のグラフを図8に示す。 Fig. 8 shows the graph for additional question 7 (eye fatigue, blurred vision, difficulty seeing).

追加設問9(夜眠れない、寝つきが悪い)のグラフを図9に示す。 FIG. 9 shows a graph of additional question 9 (cannot sleep at night, difficulty falling asleep).

追加設問13(便秘気味だ)のグラフを図10に示す。 FIG. 10 shows the graph for additional question 13 (I feel constipated).

「人の名前が思い出せない等の物忘れが多い」、「目が疲れる、目がかすむ、見えづらい」の2問は1%水準で有意差が認められ、効果があることが強く示唆される。また、「頭が重い、身体が重い」、「集中力が持続しない、たりない」、「夜眠れない、寝つきが悪い」「便秘気味だ」の、4つの追加設問は5%水準で有意差が認められ、効果があることが示唆された。今回の試験により、実施の形態に係る体調不良改善食品に、心理状態の活気、活力の向上効果があることが示唆され、物忘れの改善、集中力の向上、眼精疲労の改善、睡眠の質の向上、便秘改善作用があることが示唆された。 There was a significant difference at the 1% level for the two questions, "I often forget things such as being unable to remember people's names," and "My eyes are tired, my eyes are blurred, and I have trouble seeing." In addition, there was a significant difference at the 5% level for four additional questions: "My head feels heavy, my body feels heavy," "I can't maintain or lose concentration," "I can't sleep at night, I have trouble falling asleep," and "I feel constipated." was observed and suggested to be effective. This test suggests that the food for improving poor physical condition according to the embodiment has the effect of improving mental vitality and vitality, improving forgetfulness, improving concentration, improving eye strain, and improving sleep quality. It was suggested that it has an effect of improving constipation and improving constipation.

なお、上述した体調不良改善食品は、第1工程S101,第2工程S102,第3工程S103を経ることで得られるものである。この体調不良改善食品を摂取することで、活力の低下や認知機能の低下などが改善できるようになる。ここで、本発明の体調不良改善食品の有効成分となる物質の主成分は、上述したように、プラズマローゲンを主とする脂質であることが分析の結果判明している。 The food for improving physical condition described above is obtained through the first step S101, the second step S102, and the third step S103. By ingesting this poor physical condition improvement food, it becomes possible to improve the decline of vitality and the decline of cognitive function. Here, as a result of analysis, it has been found that the main ingredient of the substance that is the active ingredient of the food for improving poor physical condition of the present invention is, as described above, a lipid mainly composed of plasmalogen.

しかしながら、プラズマローゲンを主とする脂質の全てが、上述した活力の低下や認知機能の低下などの体調不良改善の効果が得られるものとは言えない。一方、第1工程S101,第2工程S102,第3工程S103を経ることで得られる、プラズマローゲンを主とする脂質など体調不良改善食品に含まれる成分を、現時点の分析技術で完全に特定(同定)することは、不可能であると考えられる。したがって、本発明の体調不良改善食品について、本発明の効果に寄与する成分を明確に特定するなどして、体調不良改善食品をその構造または特性により直接特定することは、おおよそ実際的ではないと考えられる。 However, it cannot be said that all lipids, mainly plasmalogens, have the effect of improving poor physical condition such as the above-mentioned decrease in vitality and cognitive function. On the other hand, the ingredients contained in the food for improving poor physical condition, such as lipids, mainly plasmalogen, obtained through the first step S101, the second step S102, and the third step S103, are completely specified by the current analysis technology ( identification) would be impossible. Therefore, for the food for improving poor physical condition of the present invention, it is generally not practical to directly specify the food for improving poor physical condition by its structure or characteristics, such as by clearly specifying the ingredients that contribute to the effects of the present invention. Conceivable.

以上に説明したように、本発明によれば、乾燥したホタテガイの外套膜より、窒素雰囲気下でエタノール抽出した抽出液を濃縮した濃縮液に、食用油および酸化防止剤を加えて調整したので、体調不良改善食品を経口摂取することで、活力の低下や、認知機能の低下などの体調不良が改善できるようになる。本発明によれば、脳神経を亢進し、活力を向上しふさぎこみを抑制して、疲労回復させ、集中力を向上させることができる。 As described above, according to the present invention, an extract obtained by extracting ethanol from a dried scallop mantle under a nitrogen atmosphere is concentrated, and edible oil and an antioxidant are added to the concentrate. By orally ingesting food for improving poor physical condition, it becomes possible to improve poor physical condition such as a decrease in vitality and a decrease in cognitive function. According to the present invention, cranial nerves can be stimulated, vitality can be improved, depression can be suppressed, fatigue can be recovered, and concentration can be improved.

なお、本発明は以上に説明した実施の形態に限定されるものではなく、本発明の技術的思想内で、当分野において通常の知識を有する者により、多くの変形および組み合わせが実施可能であることは明白である。 It should be noted that the present invention is not limited to the embodiments described above, and many modifications and combinations can be implemented by those skilled in the art within the technical concept of the present invention. It is clear.

Claims (4)

乾燥したホタテガイの外套膜よりエタノール抽出した抽出液を得る第1工程と、
前記抽出液を濃縮して濃縮液を得る第2工程と、
前記濃縮液に食用油および酸化防止剤を加えて調整する第3工程と
により生成し、
体調不良改善に用いられる体調不良改善食品。
A first step of obtaining an extract obtained by ethanol extraction from the dried scallop mantle;
a second step of concentrating the extract to obtain a concentrate;
and a third step of adjusting the concentrate by adding an edible oil and an antioxidant,
A poor physical condition improving food used for improving poor physical condition.
請求項1記載の体調不良改善食品において、
前記抽出液には、プラズマローゲンが含まれ、
前記第3工程は、プラズマローゲン含有率が1%以上となる範囲で調整する
ことを特徴とする体調不良改善食品。
In the food for improving poor physical condition according to claim 1,
The extract contains plasmalogen,
The food for improving poor physical condition, wherein in the third step, the plasmalogen content is adjusted within a range of 1% or more.
請求項1または2記載の体調不良改善食品において、
前記第1工程は、酸素を含まない雰囲気で実施することを特徴とする体調不良改善食品。
In the food for improving poor physical condition according to claim 1 or 2,
The food for improving poor physical condition, wherein the first step is performed in an oxygen-free atmosphere.
請求項3記載の体調不良改善食品において、
前記第1工程は、窒素雰囲気下で実施することを特徴とする体調不良改善食品。
In the food for improving poor physical condition according to claim 3,
The food for improving poor physical condition, wherein the first step is performed in a nitrogen atmosphere.
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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019140919A (en) 2018-02-16 2019-08-29 株式会社 レオロジー機能食品研究所 Method for producing functional material containing plasmalogen
WO2019171619A1 (en) 2018-03-08 2019-09-12 日本薬品株式会社 Method for producing plasmalogen-containing composition
WO2020040291A1 (en) 2018-08-24 2020-02-27 日本薬品株式会社 Plasmalogen-containing composition for increasing memorization ability
JP2020176086A (en) 2019-04-18 2020-10-29 株式会社 レオロジー機能食品研究所 Method for producing cranial nerve inflammation inhibiting composition

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019140919A (en) 2018-02-16 2019-08-29 株式会社 レオロジー機能食品研究所 Method for producing functional material containing plasmalogen
WO2019171619A1 (en) 2018-03-08 2019-09-12 日本薬品株式会社 Method for producing plasmalogen-containing composition
WO2020040291A1 (en) 2018-08-24 2020-02-27 日本薬品株式会社 Plasmalogen-containing composition for increasing memorization ability
JP2020176086A (en) 2019-04-18 2020-10-29 株式会社 レオロジー機能食品研究所 Method for producing cranial nerve inflammation inhibiting composition

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