JP7057668B2 - 治療剤に対する抵抗性の診断に使用するためのERCC1アイソフォーム3のmRNAおよび/またはタンパク質ならびにこのmRNAおよび/またはタンパク質を使用する治療剤に対する抵抗性を診断するための方法 - Google Patents
治療剤に対する抵抗性の診断に使用するためのERCC1アイソフォーム3のmRNAおよび/またはタンパク質ならびにこのmRNAおよび/またはタンパク質を使用する治療剤に対する抵抗性を診断するための方法 Download PDFInfo
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- JP7057668B2 JP7057668B2 JP2017513004A JP2017513004A JP7057668B2 JP 7057668 B2 JP7057668 B2 JP 7057668B2 JP 2017513004 A JP2017513004 A JP 2017513004A JP 2017513004 A JP2017513004 A JP 2017513004A JP 7057668 B2 JP7057668 B2 JP 7057668B2
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6804—Nucleic acid analysis using immunogens
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- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
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- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- Chemical & Material Sciences (AREA)
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- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
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- Microbiology (AREA)
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- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14185247 | 2014-09-18 | ||
| EP14185247.5 | 2014-09-18 | ||
| PCT/EP2015/071170 WO2016042009A1 (en) | 2014-09-18 | 2015-09-16 | Mrna and/or protein of ercc1 isoform 3 for use in diagnosing a resistance against a therapeutic agent and method for diagnosing a resistance against a therapeutic agent using said mrna and/or protein |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020168483A Division JP2021019612A (ja) | 2014-09-18 | 2020-10-05 | 治療剤に対する抵抗性の診断に使用するためのERCC1アイソフォーム3のmRNAおよび/またはタンパク質ならびにこのmRNAおよび/またはタンパク質を使用する治療剤に対する抵抗性を診断するための方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017529074A JP2017529074A (ja) | 2017-10-05 |
| JP2017529074A5 JP2017529074A5 (https=) | 2018-08-23 |
| JP7057668B2 true JP7057668B2 (ja) | 2022-04-20 |
Family
ID=51542262
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017513004A Active JP7057668B2 (ja) | 2014-09-18 | 2015-09-16 | 治療剤に対する抵抗性の診断に使用するためのERCC1アイソフォーム3のmRNAおよび/またはタンパク質ならびにこのmRNAおよび/またはタンパク質を使用する治療剤に対する抵抗性を診断するための方法 |
| JP2020168483A Pending JP2021019612A (ja) | 2014-09-18 | 2020-10-05 | 治療剤に対する抵抗性の診断に使用するためのERCC1アイソフォーム3のmRNAおよび/またはタンパク質ならびにこのmRNAおよび/またはタンパク質を使用する治療剤に対する抵抗性を診断するための方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020168483A Pending JP2021019612A (ja) | 2014-09-18 | 2020-10-05 | 治療剤に対する抵抗性の診断に使用するためのERCC1アイソフォーム3のmRNAおよび/またはタンパク質ならびにこのmRNAおよび/またはタンパク質を使用する治療剤に対する抵抗性を診断するための方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20170233826A1 (https=) |
| EP (1) | EP3194616B1 (https=) |
| JP (2) | JP7057668B2 (https=) |
| WO (1) | WO2016042009A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20200377955A1 (en) * | 2017-06-20 | 2020-12-03 | Liquid Genomics, Inc. | USE OF CELL-FREE CIRCULATING RNA (cfRNA) EXPRESSION OF PD-L1 AND ERCC1 IN PLASMA TO MONITOR RESPONSE TO THERAPY IN NSCLC |
| KR102780643B1 (ko) * | 2020-11-04 | 2025-03-17 | 한국과학기술원 | 비기능성 전사체를 이용한 parp 저해제 또는 dna 손상 약물 감수성 판정방법 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE309393T1 (de) * | 2001-09-06 | 2005-11-15 | Adnagen Ag | Verfahren zum qualitativen und/oder quantitativen nachweis von zellen |
| US9702875B2 (en) * | 2006-03-14 | 2017-07-11 | Institute Gustave-Roussy | Expression of isoform 202 of ERCC1 for predicting response to cancer chemotherapy |
| EP2008102A4 (en) * | 2006-04-18 | 2009-07-08 | Wellstat Biologics Corp | DETECTION OF PROTEINS IN NEOPLASTIC CELLS IN CIRCULATION |
| EP2233589A1 (en) * | 2009-03-19 | 2010-09-29 | Institut Gustave Roussy | MSH2 and adjuvant cisplatin-based chemotherapy in non-small-cell lung cancer |
| JP2013504064A (ja) * | 2009-09-03 | 2013-02-04 | ザ スクリプス リサーチ インスティチュート | 循環腫瘍細胞を分類する方法 |
| TWI577389B (zh) * | 2010-10-14 | 2017-04-11 | 維里德克斯有限責任公司 | 使用多專一性捕捉及雞尾酒檢測試劑檢測胰臟病患之循環腫瘤細胞的方法及套組 |
-
2015
- 2015-09-16 JP JP2017513004A patent/JP7057668B2/ja active Active
- 2015-09-16 EP EP15766784.1A patent/EP3194616B1/en active Active
- 2015-09-16 WO PCT/EP2015/071170 patent/WO2016042009A1/en not_active Ceased
- 2015-09-16 US US15/511,837 patent/US20170233826A1/en not_active Abandoned
-
2020
- 2020-10-05 JP JP2020168483A patent/JP2021019612A/ja active Pending
Non-Patent Citations (2)
| Title |
|---|
| Clinical Chemistry,2014年,Vol.60,No.10,p.1282-1289 |
| The New England Journal of Medicine,2013年,Vol.368,No.12,p.1101-1110 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3194616B1 (en) | 2020-07-29 |
| US20170233826A1 (en) | 2017-08-17 |
| WO2016042009A1 (en) | 2016-03-24 |
| JP2017529074A (ja) | 2017-10-05 |
| EP3194616A1 (en) | 2017-07-26 |
| JP2021019612A (ja) | 2021-02-18 |
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